Successful Treatment of a Patient with Glioblastoma and a Germline POLE Mutation: Where Next? uri icon

Overview

abstract

  • Hypermutation and elevated neoantigen count in glioblastoma occurred in a patient harboring a germline POLE mutation and are associated with a clinical and antitumor immune response to PD-1 blockade. Cancer Discov; 6(11); 1210-11. ©2016 AACR.See related article by Johanns et al., p. 1230.

publication date

  • November 1, 2016

Research

keywords

  • DNA Polymerase II
  • Glioblastoma
  • Programmed Cell Death 1 Receptor

Identity

PubMed Central ID

  • PMC5109825

Scopus Document Identifier

  • 84995470056

PubMed ID

  • 27807100

Additional Document Info

volume

  • 6

issue

  • 11