Cancer discovery
Journal
Overview
publication venue for
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The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients.
2019
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Chromothripsis-mediated small cell lung carcinoma.
2024
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Iron Chelation Therapy Elicits Innate Immune Control of Metastatic Ovarian Cancer.
2024
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A classical epithelial state drives acute resistance to KRAS inhibition in pancreas cancer.
2024
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Clonal Lineage Tracing with Somatic Delivery of Recordable Barcodes Reveals Migration Histories of Metastatic Prostate Cancer.
2024
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CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype Specific Vulnerability in IDH2- and TET2-Mutant Cells.
2024
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A next-generation BRAF inhibitor overcomes resistance to BRAF inhibition in patients with BRAF-mutant cancers using pharmacokinetics-informed dose escalation.
2024
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ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer.
2024
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Elucidating the Cell Surfaceome to Accelerate Cancer Drug Development..
14.
2024
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Glioblastoma: Not Just Another Cancer..
14.
2024
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Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data.
2024
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Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy.
2024
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Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms.
2024
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Non-invasive detection of neuroendocrine prostate cancer through targeted cell-free DNA methylation.
2024
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Cancer Evolution: A Multifaceted Affair.
2023
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ESR1 F404 mutations and acquired resistance to fulvestrant in ESR1 mutant breast cancer.
2023
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Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma.
2023
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Disruption of SUV39H1-mediated H3K9 methylation sustains CAR T cell function.
2023
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Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer.
2023
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Molecular characterization of endometrial carcinomas in Black and White patients reveals disparate drivers with therapeutic implications.
2023
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Dynamic glycoprotein hyposialylation promotes chemotherapy evasion and metastatic seeding of quiescent circulating tumor cell clusters in breast cancer.
2023
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Moving Spatially Resolved Multiplexed Protein Profiling toward Clinical Oncology..
13.
2023
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Programming CAR T Cell Tumor Recognition: Tuned Antigen Sensing and Logic Gating..
13.
2023
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LKB1-dependent regulation of TPI1 creates a divergent metabolic liability between human and mouse lung adenocarcinoma.
2023
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Molecular Characterization of Acquired Resistance to KRASG12C-EGFR Inhibition in Colorectal Cancer..
13.
2023
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Genetic Ancestry Correlates with Somatic Differences in a Real-World Clinical Cancer Sequencing Cohort..
12.
2022
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The AACR Journals: Advancing Progress Toward the AACR's 115-Year Mission..
12.
2022
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A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma..
12.
2022
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Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation..
12.
2022
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The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation..
12.
2022
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African Ancestry Associated Gene Expression Profiles in Triple Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent.
2022
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Small-molecule inhibition of the acyl-lysine reader ENL as a strategy against acute myeloid leukemia.
2022
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PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry.
2022
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BCL10 mutations define distinct dependencies guiding precision therapy for DLBCL.
2022
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Enhancing the Trajectories of Cancer Health Disparities Research: Improving Clinical Applications of Diversity, Equity, Inclusion, and Accessibility..
12.
2022
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Tumor-derived Lysophosphatidic Acid Blunts Protective Type-I Interferon Responses in Ovarian Cancer.
2022
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SETD2 haploinsufficiency enhances germinal center-associated AICDA somatic hypermutation to drive B cell lymphomagenesis.
2022
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Cancer Causative Mutations Occurring in Early Embryogenesis.
2021
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Multiomic Analysis of Lung Tumors Defines Pathways Activated in Neuroendocrine Transformation..
11.
2021
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Rlf-Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer..
11.
2021
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Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma.
2021
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Prolonged SARS-CoV-2 Infection in Patients with Lymphoid Malignancies..
12.
2021
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Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis..
12.
2021
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Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung..
12.
2021
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INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors..
12.
2021
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AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia..
11.
2021
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CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory..
11.
2021
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Retraction: Increased Levels of COX-2 and Prostaglandin E2 Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women..
11.
2021
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Genomics and Cancer Disparities: The Justice and Power of Inclusion..
11.
2021
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Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis..
11.
2021
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LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms..
11.
2021
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Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium..
11.
2021
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Clinical and Biological Subtypes of B-cell Lymphoma Revealed by Microenvironmental Signatures..
11.
2021
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Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence..
11.
2021
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A Call to Action: Dismantling Racial Injustices in Preclinical Research and Clinical Care of Black Patients Living with Small Cell Lung Cancer..
11.
2020
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SWI/SNF Complex Mutations Promote Thyroid Tumor Progression and Insensitivity to Redifferentiation Therapies..
11.
2020
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The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells..
11.
2020
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TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors..
11.
2020
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Deep Learning to Estimate RECIST in Patients with NSCLC Treated with PD-1 Blockade..
11.
2020
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Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML..
10.
2020
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An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants..
10.
2020
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Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy..
10.
2020
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PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2V617F-Mutant MPN..
10.
2020
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Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition..
10.
2020
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Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition..
10.
2020
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Lineage Reversion Drives WNT Independence in Intestinal Cancer..
10.
2020
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The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer..
10.
2020
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EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer..
10.
2020
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Impact of PD-1 Blockade on Severity of COVID-19 in Patients with Lung Cancers..
10.
2020
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Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis..
10.
2020
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Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas..
10.
2020
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HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers..
10.
2020
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Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization..
10.
2020
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Pan-Cancer Efficacy of Vemurafenib in BRAF V600-Mutant Non-Melanoma Cancers..
10.
2020
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Characteristics and Outcome of AKT1 E17K-Mutant Breast Cancer Defined through AACR Project GENIE, a Clinicogenomic Registry..
10.
2020
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Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma..
10.
2020
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Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer..
10.
2019
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Distinct Colorectal Cancer-Associated APC Mutations Dictate Response to Tankyrase Inhibition..
9.
2019
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Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis..
9.
2019
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V211D Mutation in MEK1 Causes Resistance to MEK Inhibitors in Colon Cancer..
9.
2019
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Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia..
9.
2019
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Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML..
9.
2019
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A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation..
9.
2019
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Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis..
9.
2019
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Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer..
9.
2019
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BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress..
9.
2019
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Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition..
9.
2019
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Transcriptomic Profiling of the Tumor Microenvironment Reveals Distinct Subgroups of Clear Cell Renal Cell Cancer: Data from a Randomized Phase III Trial..
9.
2019
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A Phase I/Ib Trial of the VEGFR-Sparing Multikinase RET Inhibitor RXDX-105..
9.
2018
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EGFR and MET Amplifications Determine Response to HER2 Inhibition in ERBB2-Amplified Esophagogastric Cancer..
9.
2018
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Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models..
9.
2018
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Integrative Molecular Characterization of Malignant Pleural Mesothelioma..
8.
2018
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EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC..
9.
2018
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TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis..
8.
2018
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The Genetic Landscape and Clonal Evolution of Breast Cancer Resistance to Palbociclib plus Fulvestrant in the PALOMA-3 Trial..
8.
2018
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Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins..
8.
2018
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Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma..
8.
2018
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MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors..
8.
2018
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Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia..
8.
2018
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Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer..
8.
2018
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STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma..
8.
2018
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Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers..
8.
2018
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Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties..
8.
2018
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Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAFV600E-Mutant Colorectal Cancer..
8.
2018
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MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia..
8.
2018
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Accelerating Discovery of Functional Mutant Alleles in Cancer..
8.
2017
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First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study..
8.
2017
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Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple-Negative Breast Cancer..
8.
2017
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FOXF1 Defines the Core-Regulatory Circuitry in Gastrointestinal Stromal Tumor..
8.
2017
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Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer..
8.
2017
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Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma..
7.
2017
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A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors..
7.
2017
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Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations..
7.
2017
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Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers..
7.
2017
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Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies..
7.
2017
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Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine..
7.
2017
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Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity..
7.
2017
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BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells..
7.
2017
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Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia..
7.
2017
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Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1)..
7.
2017
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The Genetic Basis of Hepatosplenic T-cell Lymphoma..
7.
2017
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Activating ESR1 Mutations Differentially Affect the Efficacy of ER Antagonists..
7.
2016
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Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers..
7.
2016
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The Master Neural Transcription Factor BRN2 Is an Androgen Receptor-Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer..
7.
2016
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CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas..
7.
2016
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A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer..
6.
2016
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Systematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer..
6.
2016
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Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma..
6.
2016
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DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia..
6.
2016
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Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms..
6.
2015
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NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition..
5.
2015
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PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex..
5.
2015
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Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in EGFR-Mutant Lung Cancer..
5.
2015
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Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping..
5.
2015
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Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases..
5.
2015
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MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2..
5.
2015
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Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma..
5.
2015
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Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis..
5.
2015
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The genetics of splicing in neuroblastoma..
5.
2015
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Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth..
5.
2015
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JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response..
5.
2015
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Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders..
5.
2014
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Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes..
4.
2014
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Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma..
4.
2014
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Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma..
4.
2014
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Dual inhibition of EGFR with afatinib and cetuximab in kinase inhibitor-resistant EGFR-mutant lung cancer with and without T790M mutations..
4.
2014
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Synthetic lethality in ATM-deficient RAD50-mutant tumors underlies outlier response to cancer therapy..
4.
2014
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Acquired initiating mutations in early hematopoietic cells of CLL patients..
4.
2014
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Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition..
4.
2014
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A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity..
4.
2014
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Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer..
4.
2014
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Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion..
4.
2014
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RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis..
4.
2014
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Rapid induction of apoptosis by PI3K inhibitors is dependent upon their transient inhibition of RAS-ERK signaling..
4.
2014
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Towards a unified model of RAF inhibitor resistance..
4.
2014
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Androgen receptor signaling regulates DNA repair in prostate cancers..
3.
2013
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Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma..
3.
2013
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ERK pathway inhibitors: how low should we go?.
3.
2013
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ZNF365 promotes stability of fragile sites and telomeres..
3.
2013
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Unbiased metabolite profiling indicates that a diminished thymidine pool is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine..
3.
2013
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Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1..
3.
2013
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Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas..
3.
2013
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TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia..
3.
2013
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First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement..
3.
2013
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Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression..
3.
2012
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Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention..
3.
2012
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Metabolomics strategy reveals subpopulation of liposarcomas sensitive to gemcitabine treatment..
2.
2012
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Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia..
2.
2012
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Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer..
2.
2012
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Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors..
2.
2012
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HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation..
2.
2012
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microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma..
2.
2012
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Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent..
2.
2012
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Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors..
2.
2012
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Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen..
2.
2012
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miR-23a promotes the transition from indolent to invasive colorectal cancer..
2.
2012
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Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women..
2.
2012
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MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer..
2.
2012
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Genomic complexity and AKT dependence in serous ovarian cancer..
2.
2012
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Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas..
1.
2011
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Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer..
1.
2011
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High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing..
2.
2011
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Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets..
1.
2011
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An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway..
1.
2011
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Ovarian cancer spheroids use myosin-generated force to clear the mesothelium..
1.
2011
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mTOR kinase inhibition causes feedback-dependent biphasic regulation of AKT signaling..
1.
2011
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Characterization of KRAS rearrangements in metastatic prostate cancer..
1.
2011
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PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network..
1.
2011
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mRNA Export as a Novel Cancer-Specific Dependency.
2021
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Suppressing Nucleotide Exchange to Inhibit KRAS-Mutant Tumors.
2021
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Overcoming Antigen Escape with CAR T-cell Therapy.
2015
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MYC, MAX, and small cell lung cancer.
2014
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Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.
2013
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All the World's a Stage: Facilitating Discovery Science and Improved Cancer Care through the Global Alliance for Genomics and Health.
2015
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ADCs or: How I Learned to Stop Worrying and Love Chemotherapy..
13.
2023
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Oncogenic IDH1 Mutation Imparts Therapeutically Targetable Metabolic Dysfunction in Multiple Tumor Types..
13.
2023
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Vive la Résistance: T-cell Immunity in the Protection against SARS-CoV-2 Infection..
12.
2022
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WNT as a Driver and Dependency in Cancer.
2021
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Artificial Intelligence in Cancer Research and Precision Medicine.
2021
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Diffuse Glioma Heterogeneity and Its Therapeutic Implications.
2021
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The Expanding World of N-MYC-Driven Tumors.
2018
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Targeting ALK: Precision Medicine Takes on Drug Resistance.
2017
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Mesothelin-Targeted CARs: Driving T Cells to Solid Tumors.
2015
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The basic principles of chimeric antigen receptor design.
2013
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Negative feedback and adaptive resistance to the targeted therapy of cancer.
2012
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Metastasis-Initiating Cells and Ecosystems.
2021
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Altered RNA Processing in Cancer Pathogenesis and Therapy.
2019
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Patient-derived xenograft models: an emerging platform for translational cancer research.
2014
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