Karim, Salim

Publications

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selected publications

Evaluating diagnostic accuracy of an RT-PCR test for the detection of SARS-CoV-2 in saliva. Diagnostic and prognostic research. 2024 Academic Article GET IT
Circulating immunoglobulins and transient lymphocytopenia in a sub-study of CAPRISA 012B, testing HIV monoclonal antibodies in a phase 1 trial. Scientific reports. 2024 Academic Article GET IT
Incidence of herpes simplex virus type 2 positivity among women living with human immunodeficiency virus in South Africa. International journal of STD & AIDS. 2023 Academic Article GET IT
Field evaluations of four SARS-CoV-2 rapid antigen tests during SARS-CoV-2 Delta variant wave in South Africa. Diagnostic and prognostic research. 2023 Academic Article GET IT
Times cited: 137
Vaccine inequity and hesitancy persist-we must tackle both. BMJ (Clinical research ed.). 2023 Editorial Article GET IT
Times cited: 3
Building on Pasteur's legacy: producing vaccines in Africa. Lancet (London, England). 2022 Academic Article GET IT
Times cited: 1
A multinational Delphi consensus to end the COVID-19 public health threat. Nature. 2022 Academic Article GET IT
Clinical Evaluation of Severe Acute Respiratory Syndrome Coronavirus 2 Rapid Antigen Tests During the Omicron Wave in South Africa. The Journal of infectious diseases. 2022 Academic Article GET IT
Times cited: 6
The Lancet Commission on lessons for the future from the COVID-19 pandemic. Lancet (London, England). 2022 Review GET IT
Times cited: 418
Mortality in HIV and tuberculosis patients following implementation of integrated HIV-TB treatment: Results from an open-label cluster-randomized trial. EClinicalMedicine. 2022 Academic Article GET IT
Times cited: 3
Omicron infection of vaccinated individuals enhances neutralizing immunity against the Delta variant. 2022 GET IT
Times cited: 357
SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape. Cell host & microbe. 2022 Academic Article GET IT
Times cited: 144
SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity. 2021 GET IT
Institutional and behaviour-change interventions to support COVID-19 public health measures: a review by the Lancet Commission Task Force on public health measures to suppress the pandemic. International health. 2021 Review GET IT
Times cited: 39
A cluster-randomized controlled trial to improve the quality of integrated HIV-tuberculosis services in primary healthcareclinics in South Africa. Journal of the International AIDS Society. 2021 Academic Article GET IT
Times cited: 6
Recent Semen Exposure Impacts the Cytokine Response and Bacterial Vaginosis in Women. Frontiers in immunology. 2021 Academic Article GET IT
Times cited: 10
Vaccines and SARS-CoV-2 variants: the urgent need for a correlate of protection. Lancet (London, England). 2021 Letter GET IT
Times cited: 41
Genital and systemic immune effects of the injectable, contraceptive norethisterone enanthate (NET-EN), in South African women. American journal of reproductive immunology (New York, N.Y. : 1989). 2021 Academic Article GET IT
Times cited: 1
Future scenarios for the COVID-19 pandemic. Lancet (London, England). 2021 Academic Article GET IT
Times cited: 128
SARS-CoV-2 variants and ending the COVID-19 pandemic. Lancet (London, England). 2021 Academic Article GET IT
Times cited: 414
Improving survival with tuberculosis & HIV treatment integration: A mini-review. The Indian journal of medical research. 2019 Review GET IT
Times cited: 5
Detection of Tuberculosis Recurrence, Diagnosis and Treatment Response by a Blood Transcriptomic Risk Signature in HIV-Infected Persons on Antiretroviral Therapy. Frontiers in microbiology. 2019 Academic Article GET IT
Times cited: 35
Optimising the accuracy of HIV drug resistance assays. The lancet. HIV. 2018 Comment GET IT
Acceptability of Early Antiretroviral Therapy Among South African Women. AIDS and behavior. 2018 Academic Article GET IT
Times cited: 19
Genital inflammation undermines the effectiveness of tenofovir gel in preventing HIV acquisition in women. Nature medicine. 2018 Academic Article GET IT
Times cited: 93
Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization. 2017 GET IT
Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope. Journal of virology. 2017 Academic Article GET IT
Times cited: 30
Closing the NIH Fogarty Center threatens US and global health. Lancet (London, England). 2017 Letter GET IT
Times cited: 2
Transmission networks and risk of HIV infection in KwaZulu-Natal, South Africa: a community-wide phylogenetic study. The lancet. HIV. 2016 Academic Article GET IT
Times cited: 218
Assessing progress with HIV incidence in national cohorts. The lancet. HIV. 2016 Comment GET IT
Times cited: 2
Efficacy and safety of tenofovir-containing antiretroviral therapy in women who acquired HIV while enrolled in tenofovir gel prophylaxis trials. Antiviral therapy. 2016 Academic Article GET IT
Times cited: 2
Broadly neutralizing antibody specificities detected in the genital tract of HIV-1 infected women. AIDS (London, England). 2016 Academic Article GET IT
Times cited: 15
Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel. Mucosal immunology. 2016 Academic Article GET IT
Times cited: 11
Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell reports. 2015 Academic Article GET IT
Times cited: 43
Restoration of CD4+ Responses to Copathogens in HIV-Infected Individuals on Antiretroviral Therapy Is Dependent on T Cell Memory Phenotype. Journal of immunology (Baltimore, Md. : 1950). 2015 Academic Article GET IT
Times cited: 22
South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication. Retrovirology. 2015 Academic Article GET IT
Times cited: 18
Appeal to global donors to save the Treatment Action Campaign. Lancet (London, England). 2014 Letter GET IT
Times cited: 2
Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies. Cell host & microbe. 2014 Academic Article GET IT
Times cited: 120
HIV infection in high school students in rural South Africa: role of transmissions among students. AIDS research and human retroviruses. 2014 Academic Article GET IT
Times cited: 18
HIV-1 specific IgA detected in vaginal secretions of HIV uninfected women participating in a microbicide trial in Southern Africa are primarily directed toward gp120 and gp140 specificities. PloS one. 2014 Academic Article GET IT
Times cited: 29
Assessing adherence in the CAPRISA 004 tenofovir gel HIV prevention trial: results of a nested case-control study. AIDS and behavior. 2014 Academic Article GET IT
Times cited: 9
Impact of an adherence intervention on the effectiveness of tenofovir gel in the CAPRISA 004 trial. AIDS and behavior. 2014 Academic Article GET IT
Times cited: 21
Measuring adherence by visual inspection of returned empty gel applicators in the CAPRISA 004 microbicide trial. AIDS and behavior. 2014 Academic Article GET IT
Times cited: 6
Trial participation disclosure and gel use behavior in the CAPRISA 004 tenofovir gel trial. AIDS care. 2014 Academic Article GET IT
Times cited: 15
Identification of broadly neutralizing antibody epitopes in the HIV-1 envelope glycoprotein using evolutionary models. Virology journal. 2013 Academic Article GET IT
Times cited: 13
Changes to antiretroviral drug regimens during integrated TB-HIV treatment: results of the SAPiT trial. Antiviral therapy. 2013 Academic Article GET IT
Times cited: 19
No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial. PloS one. 2013 Academic Article GET IT
Times cited: 10
Changes in Natural Killer cell activation and function during primary HIV-1 Infection. PloS one. 2013 Academic Article GET IT
Times cited: 49
Vertical T cell immunodominance and epitope entropy determine HIV-1 escape. The Journal of clinical investigation. 2012 Academic Article GET IT
Times cited: 160
Intersubtype differences in the effect of a rare p24 gag mutation on HIV-1 replicative fitness. Journal of virology. 2012 Academic Article GET IT
Times cited: 10
Safety of tenofovir gel, a vaginal microbicide, in South African women: results of the CAPRISA 004 Trial. Antiviral therapy. 2012 Academic Article GET IT
Times cited: 17
CAPRISA 004 tenofovir microbicide trial: no impact of tenofovir gel on the HIV transmission bottleneck. The Journal of infectious diseases. 2012 Academic Article GET IT
Times cited: 15
HIV prevalence among high school learners - opportunities for school-based HIV testing programmes and sexual reproductive health services. World health & population. 2012 Academic Article GET IT
Times cited: 6
HIV prevention transformed: the new prevention research agenda. Lancet (London, England). 2011 Review GET IT
Times cited: 230
Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2011 Academic Article GET IT
Times cited: 66
Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection. Journal of virology. 2010 Academic Article GET IT
Times cited: 69
Uptake of provider-initiated HIV testing and counseling among women attending an urban sexually transmitted disease clinic in South Africa - missed opportunities for early diagnosis of HIV infection. AIDS care. 2010 Academic Article GET IT
Times cited: 32
Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin. Virology. 2010 Academic Article GET IT
Times cited: 92
Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression. AIDS (London, England). 2010 Academic Article GET IT
Times cited: 171
AIDS research must link to local policy. Nature. 2010 Academic Article GET IT
Times cited: 11
Salim "Slim" Abdool Karim: attacking AIDS in South Africa. Interview by Amy Maxmen. The Journal of experimental medicine. 2009 Article GET IT
Times cited: 1
Achieving the health Millennium Development Goals for South Africa: challenges and priorities. Lancet (London, England). 2009 Review GET IT
Times cited: 186
Interleukin-10 promoter polymorphisms influence HIV-1 susceptibility and primary HIV-1 pathogenesis. The Journal of infectious diseases. 2009 Academic Article GET IT
Times cited: 66
Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection. The Journal of infectious diseases. 2009 Academic Article GET IT
Times cited: 46
Re: "Enhancement of HIV infection by cellulose sulfate," by Tao et al. AIDS research and human retroviruses. 2009 Letter GET IT
Times cited: 1
Scientists stand by decision to join Mbeki's AIDS panel. Nature. 2009 Letter GET IT
Times cited: 1
Conserved positive selection signals in gp41 across multiple subtypes and difference in selection signals detectable in gp41 sequences sampled during acute and chronic HIV-1 subtype C infection. Virology journal. 2008 Academic Article GET IT
Times cited: 4
Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia. Journal of virology. 2008 Academic Article GET IT
Times cited: 507
Relationship between levels of inflammatory cytokines in the genital tract and CD4+ cell counts in women with acute HIV-1 infection. The Journal of infectious diseases. 2008 Academic Article GET IT
Times cited: 63
Apnea and its possible relationship to immunization in ex-premature infants. Vaccine. 2008 Academic Article GET IT
Times cited: 15
Perspective conducting HIV prevention research in South Africa. IAVI report : newsletter on international AIDS vaccine research. 2008 Article GET IT
Response to Brown et al., 'Incident and prevalent herpes simplex virus type 2 infection increases risk of HIV acquisition among women in Uganda and Zimbabwe'. AIDS (London, England). 2007 Letter GET IT
Times cited: 1
Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection. Journal of virology. 2007 Academic Article GET IT
Times cited: 107
Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection. Journal of virology. 2007 Academic Article GET IT
Times cited: 245
Utilizing nucleic acid amplification to identify acute HIV infection. AIDS (London, England). 2007 Letter GET IT
Times cited: 11
HIV incidence estimates are key to understanding the changing HIV epidemic in South Africa. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 2007 Editorial Article GET IT
Times cited: 2
Durban 2000 to Toronto 2006: the evolving challenges in implementing AIDS treatment in Africa. AIDS (London, England). 2006 Academic Article GET IT
Times cited: 6
Increasing burden of pulmonary tuberculosis in young women. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 2006 Letter GET IT
Times cited: 1
Enrolling adolescents in research on HIV and other sensitive issues: lessons from South Africa. PLoS medicine. 2006 Academic Article GET IT
Times cited: 46
The impact of incident and prevalent herpes simplex virus-2 infection on the incidence of HIV-1 infection among commercial sex workers in South Africa. Journal of acquired immune deficiency syndromes (1999). 2005 Academic Article GET IT
Times cited: 59
Heterosexual transmission of multiple highly conserved viral variants in HIV-1 subtype C-infected seronegative women. AIDS (London, England). 2004 Academic Article GET IT
Times cited: 6
Dual HIV-1 infection associated with rapid disease progression. Lancet (London, England). 2004 Academic Article GET IT
Times cited: 170
Who infects whom? HIV-1 concordance and discordance among migrant and non-migrant couples in South Africa. AIDS (London, England). 2003 Academic Article GET IT
Times cited: 234
Report from the Tenth Retrovirus Conference. Vaccines and microbicides. AIDS clinical care. 2003 Conference Paper GET IT
Safety and tolerability of vaginal PRO 2000 gel in sexually active HIV-uninfected and abstinent HIV-infected women. AIDS (London, England). 2003 Academic Article GET IT
Times cited: 103
Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial. Lancet (London, England). 2002 Academic Article GET IT
Times cited: 714
A randomized controlled trial of azithromycin versus doxycycline/ciprofloxacin for the syndromic management of sexually transmitted infections in a resource-poor setting. The Journal of antimicrobial chemotherapy. 2002 Academic Article GET IT
Times cited: 34
High incidence of HIV-1 in South Africa using a standardized algorithm for recent HIV seroconversion. Journal of acquired immune deficiency syndromes (1999). 2002 Academic Article GET IT
Times cited: 45
Socioeconomic and cultural influence in the causation of burns in the urban children of Bangladesh. The Journal of burn care & rehabilitation. 2001 Academic Article GET IT
Times cited: 62
HIV surveillance results--little grounds for optimism yet. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 2000 Academic Article GET IT
Times cited: 10
Hospital inpatient audit--information for action. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1998 Editorial Article GET IT
Times cited: 1
Is there a cure for AIDS?. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1996 Conference Paper GET IT
Potential savings from generic prescribing and generic substitution in South Africa. Health policy and planning. 1996 Academic Article GET IT
Times cited: 48
Putting the records straight--a plea for improved abortion data. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1995 Editorial Article GET IT
Times cited: 2

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Background

education and training

M.B.,Ch.B., University of KwaZulu-Natal, Nelson R. Mandela School of Medicine (South Africa) 83
Ph.D., University of Natal (South Africa) 1999
M.S., Columbia University 1988

Contact

full name

Salim Karim

VIVO Weill Cornell Medical College

Salim Karim Adjunct Professor of Medicine

Publications

selected publications

Background

education and training

Contact

full name

Phone

Publications

selected publications

Background

education and training

Contact

full name