Wong, Stephen

selected publications

ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment. Nature communications. 2020 Academic Article GET IT
Times cited: 26
OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages. EBioMedicine. 2020 Academic Article GET IT
Times cited: 10
Sepsis outcomes in solid organ transplant recipients. Transplant infectious disease : an official journal of the Transplantation Society. 2019 Academic Article GET IT
Times cited: 3
Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis. Cancer research. 2019 Comment GET IT
Times cited: 64
Driver network as a biomarker: systematic integration and network modeling of multi-omics data to derive driver signaling pathways for drug combination prediction. Bioinformatics (Oxford, England). 2019 Academic Article GET IT
Times cited: 48
Anticancer Immunotherapy by MFAP5 Blockade Inhibits Fibrosis and Enhances Chemosensitivity in Ovarian and Pancreatic Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 42
Prognostic Gene Discovery in Glioblastoma Patients using Deep Learning. Cancers. 2019 Academic Article GET IT
Times cited: 39
HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway. Stem cell reports. 2017 Academic Article GET IT
Times cited: 44
Combining deep learning and coherent anti-Stokes Raman scattering imaging for automated differential diagnosis of lung cancer. Journal of biomedical optics. 2017 Academic Article GET IT
Times cited: 75
Complete Metabolic Response on Interim ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography to Predict Long-Term Survival in Patients with Breast Cancer Undergoing Neoadjuvant Chemotherapy. The oncologist. 2017 Academic Article GET IT
Times cited: 13
Correlating mammographic and pathologic findings in clinical decision support using natural language processing and data mining methods. Cancer. 2016 Academic Article GET IT
Times cited: 30
Technical Pitfalls of Signal Truncation in Perfusion MRI of Glioblastoma. Frontiers in neurology. 2016 Academic Article GET IT
Cell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cells. Scientific reports. 2016 Academic Article GET IT
Times cited: 30
Dual CARS and SHG image acquisition scheme that combines single central fiber and multimode fiber bundle to collect and differentiate backward and forward generated photons. Biomedical optics express. 2016 Academic Article GET IT
Times cited: 1
In Vivo Visualization and Characterization of Epithelial-Mesenchymal Transition in Breast Tumors. Cancer research. 2016 Academic Article GET IT
Times cited: 65
Targeting Stromal-Cancer Cell Crosstalk Networks in Ovarian Cancer Treatment. Biomolecules. 2016 Information Resource GET IT
Times cited: 43
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance. Nature. 2015 Academic Article GET IT
Times cited: 1464
A High-content screen identifies compounds promoting the neuronal differentiation and the midbrain dopamine neuron specification of human neural progenitor cells. Scientific reports. 2015 Academic Article GET IT
Times cited: 19
Epithelial derived CTGF promotes breast tumor progression via inducing EMT and collagen I fibers deposition. Oncotarget. 2015 Academic Article GET IT
Times cited: 43
A lab-on-a-chip system integrating tissue sample preparation and multiplex RT-qPCR for gene expression analysis in point-of-care hepatotoxicity assessment. Lab on a chip. 2015 Academic Article GET IT
Times cited: 12
Risk stratification in patients with advanced-stage breast cancer by pretreatment [(18) F]FDG PET/CT. Cancer. 2015 Academic Article GET IT
Times cited: 17
Molecular dynamics simulation study reveals potential substrate entry path into γ-secretase/presenilin-1. Journal of structural biology. 2015 Academic Article GET IT
Times cited: 25
METEOR: An Enterprise Health Informatics Environment to Support Evidence-Based Medicine. IEEE transactions on bio-medical engineering. 2015 Academic Article GET IT
Times cited: 27
A computational method for clinically relevant cancer stratification and driver mutation module discovery using personal genomics profiles. BMC genomics. 2015 Academic Article GET IT
Multimodal nonlinear endo-microscopy probe design for high resolution, label-free intraoperative imaging. Biomedical optics express. 2015 Academic Article GET IT
Times cited: 19
Reconstruction of four-dimensional computed tomography lung images by applying spatial and temporal anatomical constraints using a Bayesian model. Journal of medical imaging (Bellingham, Wash.). 2015 Academic Article GET IT
Times cited: 3
Optimal drug prediction from personal genomics profiles. IEEE journal of biomedical and health informatics. 2015 Academic Article GET IT
Times cited: 43
Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model. Cell reports. 2015 Academic Article GET IT
Times cited: 52
DIGRE: Drug-Induced Genomic Residual Effect Model for Successful Prediction of Multidrug Effects. CPT: pharmacometrics & systems pharmacology. 2015 Academic Article GET IT
Times cited: 30
The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells. Cancer cell. 2015 Academic Article GET IT
Times cited: 294
On translating technology research into industrial applications. SpringerPlus. 2014 Academic Article GET IT
Integration of multiscale dendritic spine structure and function data into systems biology models. Frontiers in neuroanatomy. 2014 Information Resource GET IT
Times cited: 14
How cells explore shape space: a quantitative statistical perspective of cellular morphogenesis. BioEssays : news and reviews in molecular, cellular and developmental biology. 2014 Academic Article GET IT
Times cited: 19
Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1. Stem cells (Dayton, Ohio). 2014 Academic Article GET IT
Times cited: 102
Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induced adipose inflammation. Molecular and cellular endocrinology. 2014 Academic Article GET IT
Times cited: 71
Fractional anisotropy asymmetry and the side of seizure origin for partial onset-temporal lobe epilepsy. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2014 Academic Article GET IT
Times cited: 6
Computational analysis of image-based drug profiling predicts synergistic drug combinations: applications in triple-negative breast cancer. Molecular oncology. 2014 Academic Article GET IT
Times cited: 13
DrugComboRanker: drug combination discovery based on target network analysis. Bioinformatics (Oxford, England). 2014 Academic Article GET IT
Times cited: 138
Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling. Proceedings of the National Academy of Sciences of the United States of America. 2014 Academic Article GET IT
Times cited: 91
Mechanical unloading promotes myocardial energy recovery in human heart failure. Circulation. Cardiovascular genetics. 2014 Academic Article GET IT
Times cited: 76
Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer. Stem cells translational medicine. 2014 Academic Article GET IT
Times cited: 8
Guest editorial: Computational solutions to large-scale data management and analysis in translational and personalized medicine. IEEE journal of biomedical and health informatics. 2014 Editorial Article GET IT
Times cited: 3
Old drug new use--amoxapine and its metabolites as potent bacterial β-glucuronidase inhibitors for alleviating cancer drug toxicity. Clinical cancer research : an official journal of the American Association for Cancer Research. 2014 Academic Article GET IT
Times cited: 75
Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors. Cell research. 2014 Academic Article GET IT
Times cited: 23
Functional brain interactions during reflexive micturition are absent from spinal cord injured rats with neurogenic bladder. Neurourology and urodynamics. 2014 Academic Article GET IT
Times cited: 8
Guest Editorial- special issue on ‘-omics’ based companion diagnostics for personalized medicine. IEEE transactions on biomedical circuits and systems. 2014 Editorial Article GET IT
Times cited: 1
Predictors for cortical gray matter volume in stroke patients with confluent white matter changes. Journal of the neurological sciences. 2014 Academic Article GET IT
Times cited: 2
Estimating dynamic lung images from high-dimension chest surface motion using 4D statistical model. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. 2014 Academic Article GET IT
Times cited: 4
Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts. Stem cell reports. 2013 Academic Article GET IT
Times cited: 794
A 3D multiscale model of cancer stem cell in tumor development. BMC systems biology. 2013 Academic Article GET IT
Times cited: 21
Transcriptional signaling pathways inversely regulated in Alzheimer's disease and glioblastoma multiform. Scientific reports. 2013 Academic Article GET IT
Times cited: 35
Vasodilation by in vivo activation of astrocyte endfeet via two-photon calcium uncaging as a strategy to prevent brain ischemia. Journal of biomedical optics. 2013 Academic Article GET IT
Times cited: 9
Genome-wide analysis of DNA copy number alterations and loss of heterozygosity in intracranial germ cell tumors. Pediatric blood & cancer. 2013 Academic Article GET IT
Times cited: 30
Multimodal non-linear optical imaging for label-free differentiation of lung cancerous lesions from normal and desmoplastic tissues. Biomedical optics express. 2013 Academic Article GET IT
Times cited: 35
Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines. Drug discovery today. 2013 Information Resource GET IT
Times cited: 341
A gene signature based method for identifying subtypes and subtype-specific drivers in cancer with an application to medulloblastoma. BMC bioinformatics. 2013 Academic Article GET IT
Times cited: 53
Novel modeling of cancer cell signaling pathways enables systematic drug repositioning for distinct breast cancer metastases. Cancer research. 2013 Academic Article GET IT
Times cited: 42
The miR-223/nuclear factor I-A axis regulates glial precursor proliferation and tumorigenesis in the CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2013 Academic Article GET IT
Times cited: 47
Three-dimensional vasculature reconstruction of tumour microenvironment via local clustering and classification. Interface focus. 2013 Academic Article GET IT
Times cited: 7
A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. Nature cell biology. 2013 Academic Article GET IT
Times cited: 139
DrugMap Central: an on-line query and visualization tool to facilitate drug repositioning studies. Bioinformatics (Oxford, England). 2013 Academic Article GET IT
Times cited: 33
Chapter 17: bioimage informatics for systems pharmacology. PLoS computational biology. 2013 Information Resource GET IT
Times cited: 23
Genome-wide RNAi screening identifies genes inhibiting the migration of glioblastoma cells. PloS one. 2013 Academic Article GET IT
Times cited: 28
Tract-based spatial statistics reveal altered relationship between non-verbal reasoning abilities and white matter integrity in autism spectrum disorder. Journal of the International Neuropsychological Society : JINS. 2013 Academic Article GET IT
Times cited: 11
Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 Academic Article GET IT
Times cited: 141
Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation. Cell metabolism. 2013 Academic Article GET IT
Times cited: 311
A fast CT and CT-fluoroscopy registration algorithm with respiratory motion compensation for image-guided lung intervention. IEEE transactions on bio-medical engineering. 2013 Academic Article GET IT
Times cited: 17
Nonlinear motion compensation using cubature Kalman filter for in vivo fluorescence microendoscopy in peripheral lung cancer intervention. Journal of biomedical optics. 2013 Academic Article GET IT
Times cited: 3
Differential effects of low- and high-dose GW2974, a dual epidermal growth factor receptor and HER2 kinase inhibitor, on glioblastoma multiforme invasion. Journal of neuroscience research. 2012 Academic Article GET IT
Times cited: 9
Network-based analysis reveals stronger local diffusion-based connectivity and different correlations with oral language skills in brains of children with high functioning autism spectrum disorders. Human brain mapping. 2012 Academic Article GET IT
Times cited: 50
Microenvironmental regulation of epithelial-mesenchymal transitions in cancer. Cancer research. 2012 Review GET IT
Times cited: 257
Inter-endothelial transport of microvectors using cellular shuttles and tunneling nanotubes. Small (Weinheim an der Bergstrasse, Germany). 2012 Academic Article GET IT
Times cited: 22
Activation of the ATM-Snail pathway promotes breast cancer metastasis. Journal of molecular cell biology. 2012 Academic Article GET IT
Times cited: 97
A quantitative analytic pipeline for evaluating neuronal activities by high-throughput synaptic vesicle imaging. NeuroImage. 2012 Academic Article GET IT
Times cited: 3
Activation of the inflammasome and enhanced migration of microparticle-stimulated dendritic cells to the draining lymph node. Molecular pharmaceutics. 2012 Academic Article GET IT
Times cited: 29
Differential diagnosis of lung carcinoma with three-dimensional quantitative molecular vibrational imaging. Journal of biomedical optics. 2012 Academic Article GET IT
Times cited: 11
Predictors for cognitive decline in patients with confluent white matter hyperintensities. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2012 Academic Article GET IT
Times cited: 19
Semi-automatic segmentation software for quantitative clinical brain glioblastoma evaluation. Academic radiology. 2012 Academic Article GET IT
Times cited: 36
Methods of dendritic spine detection: from Golgi to high-resolution optical imaging. Neuroscience. 2012 Information Resource GET IT
Times cited: 58
Involvement of epidermal growth factor receptor overexpression in the promotion of breast cancer brain metastasis. Cancer. 2012 Academic Article GET IT
Times cited: 46
A minimally invasive multimodality image-guided (MIMIG) system for peripheral lung cancer intervention and diagnosis. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2012 Academic Article GET IT
Times cited: 17
Identification of small molecule inhibitors of neurite loss induced by Aβ peptide using high content screening. The Journal of biological chemistry. 2012 Academic Article GET IT
Times cited: 24
CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling. Oncogene. 2012 Academic Article GET IT
Times cited: 24
γ-Secretase modulator in Alzheimer's disease: shifting the end. Journal of Alzheimer's disease : JAD. 2012 Information Resource GET IT
Times cited: 32
A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy. Cancer research. 2011 Academic Article GET IT
Times cited: 82
Aurora-B mediated ATM serine 1403 phosphorylation is required for mitotic ATM activation and the spindle checkpoint. Molecular cell. 2011 Academic Article GET IT
Times cited: 95
The kinetochore protein Bub1 participates in the DNA damage response. DNA repair. 2011 Academic Article GET IT
Times cited: 45
Image-guided fiberoptic molecular imaging in a VX2 rabbit lung tumor model. Journal of vascular and interventional radiology : JVIR. 2011 Academic Article GET IT
Times cited: 8
Real-time monitoring of cell viability using direct electrical measurement with a patch-clamp microchip. Biomedical microdevices. 2011 Academic Article GET IT
Times cited: 9
A time-series method for automated measurement of changes in mitotic and interphase duration from time-lapse movies. PloS one. 2011 Academic Article GET IT
Times cited: 13
Motion correction for cellular-resolution multi-photon fluorescence microscopy imaging of awake head-restrained mice using speed embedded HMM. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2011 Academic Article GET IT
Times cited: 4
On-the-spot lung cancer differential diagnosis by label-free, molecular vibrational imaging and knowledge-based classification. Journal of biomedical optics. 2011 Academic Article GET IT
Times cited: 30
Use of multimode optical fibers for fiber-based coherent anti-Stokes Raman scattering microendoscopy imaging. Optics letters. 2011 Academic Article GET IT
Times cited: 21
Differential diagnosis of breast cancer using quantitative, label-free and molecular vibrational imaging. Biomedical optics express. 2011 Academic Article GET IT
Times cited: 69
An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data. Bioinformatics (Oxford, England). 2011 Academic Article GET IT
Times cited: 50
Coherent anti-Stokes Raman scattering microscopy imaging with suppression of four-wave mixing in optical fibers. Optics express. 2011 Academic Article GET IT
Times cited: 28
Label-free high-resolution imaging of prostate glands and cavernous nerves using coherent anti-Stokes Raman scattering microscopy. Biomedical optics express. 2011 Academic Article GET IT
Times cited: 70
The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models. Breast cancer research and treatment. 2011 Academic Article GET IT
Times cited: 28
Drug effects analysis on cells using a high throughput microfluidic chip. Biomedical microdevices. 2011 Academic Article GET IT
Times cited: 18
Support vector machine multiparametric MRI identification of pseudoprogression from tumor recurrence in patients with resected glioblastoma. Journal of magnetic resonance imaging : JMRI. 2011 Academic Article GET IT
Times cited: 122
Characterization of a human tumorsphere glioma orthotopic model using magnetic resonance imaging. Journal of neuro-oncology. 2011 Academic Article GET IT
Times cited: 19
Tissue Probability Map Constrained 4-D Clustering Algorithm for Increased Accuracy and Robustness in Serial MR Brain Image Segmentation. International journal of medical engineering and informatics. 2011 Academic Article GET IT
Cellular uptake and imaging studies of gadolinium-loaded single-walled carbon nanotubes as MRI contrast agents. Contrast media & molecular imaging. 2010 Academic Article GET IT
Times cited: 28
A global spatial similarity optimization scheme to track large numbers of dendritic spines in time-lapse confocal microscopy. IEEE transactions on medical imaging. 2010 Academic Article GET IT
Times cited: 12
Bayesian Peptide Peak Detection for High Resolution TOF Mass Spectrometry. IEEE transactions on signal processing : a publication of the IEEE Signal Processing Society. 2010 Academic Article GET IT
MicroRNA-integrated and network-embedded gene selection with diffusion distance. PloS one. 2010 Academic Article GET IT
Times cited: 3
Diffusion tensor-based fast marching for modeling human brain connectivity network. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2010 Academic Article GET IT
Times cited: 9
Cancer stem cell, niche and EGFR decide tumor development and treatment response: A bio-computational simulation study. Journal of theoretical biology. 2010 Academic Article GET IT
Times cited: 30
Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice. Hepatology (Baltimore, Md.). 2010 Academic Article GET IT
Times cited: 87
Neuroimaging predictors for depressive symptoms in cerebral small vessel disease. International journal of geriatric psychiatry. 2010 Academic Article GET IT
Times cited: 11
Oriented Markov random field based dendritic spine segmentation for fluorescence microscopy images. Neuroinformatics. 2010 Academic Article GET IT
Times cited: 5
Using genetic and clinical factors to predict tacrolimus dose in renal transplant recipients. Pharmacogenomics. 2010 Academic Article GET IT
Times cited: 38
Executive dysfunction and left frontal white matter hyperintensities are correlated with neuropsychiatric symptoms in stroke patients with confluent white matter hyperintensities. Dementia and geriatric cognitive disorders. 2010 Academic Article GET IT
Times cited: 22
Image-based chemical screening identifies drug efflux inhibitors in lung cancer cells. Cancer research. 2010 Academic Article GET IT
Cortical and frontal atrophy are associated with cognitive impairment in age-related confluent white-matter lesion. Journal of neurology, neurosurgery, and psychiatry. 2010 Academic Article GET IT
Times cited: 45
Fabrication of localized surface plasmon resonance fiber probes using ionic self-assembled gold nanoparticles. Sensors (Basel, Switzerland). 2010 Academic Article GET IT
Times cited: 24
Reconstruction of the neuromuscular junction connectome. Bioinformatics (Oxford, England). 2010 Academic Article GET IT
Times cited: 14
An automatic and robust algorithm of reestablishment of digital dental occlusion. IEEE transactions on medical imaging. 2010 Academic Article GET IT
Times cited: 45
Delivery of picosecond lasers in multimode fibers for coherent anti-Stokes Raman scattering imaging. Optics express. 2010 Academic Article GET IT
Times cited: 20
A computational framework for studying neuron morphology from in vitro high content neuron-based screening. Journal of neuroscience methods. 2010 Academic Article GET IT
Times cited: 11
Conditional random pattern model for copy number aberration detection. BMC bioinformatics. 2010 Academic Article GET IT
Times cited: 2
A local fast marching-based diffusion tensor image registration algorithm by simultaneously considering spatial deformation and tensor orientation. NeuroImage. 2010 Academic Article GET IT
Times cited: 15
Phenotypic analysis of images of zebrafish treated with Alzheimer's gamma-secretase inhibitors. BMC biotechnology. 2010 Academic Article GET IT
Times cited: 36
Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study. European journal of cancer. 2010 Academic Article GET IT
Times cited: 33
Towards a genome-scale kinetic model of cellular metabolism. BMC systems biology. 2010 Academic Article GET IT
Times cited: 117
A neurocomputational method for fully automated 3D dendritic spine detection and segmentation of medium-sized spiny neurons. NeuroImage. 2010 Academic Article GET IT
Times cited: 33
Computer-assisted quantitative evaluation of therapeutic responses for lymphoma using serial PET/CT imaging. Academic radiology. 2010 Academic Article GET IT
Times cited: 10
Catch the wave--nanotechnology, the future is now. IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society. 2010 Conference Paper GET IT
Times cited: 1
Image segmentation by EM-based adaptive pulse coupled neural networks in brain magnetic resonance imaging. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2009 Academic Article GET IT
Times cited: 46
Cross-platform method for identifying candidate network biomarkers for prostate cancer. IET systems biology. 2009 Academic Article GET IT
Times cited: 12
Bioluminescence imaging of heme oxygenase-1 upregulation in the Gua Sha procedure. Journal of visualized experiments : JoVE. 2009 Academic Article GET IT
Times cited: 43
Joint registration and segmentation of serial lung CT images for image-guided lung cancer diagnosis and therapy. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2009 Academic Article GET IT
Times cited: 35
A hybrid approach to automatic clustering of white matter fibers. NeuroImage. 2009 Academic Article GET IT
Times cited: 61
A novel peak detection approach with chemical noise removal using short-time FFT for prOTOF MS data. Proteomics. 2009 Academic Article GET IT
Times cited: 9
A screening platform for glioma growth and invasion using bioluminescence imaging. Laboratory investigation. Journal of neurosurgery. 2009 Academic Article GET IT
Times cited: 23
Multiple nuclei tracking using integer programming for quantitative cancer cell cycle analysis. IEEE transactions on medical imaging. 2009 Academic Article GET IT
Times cited: 106
Conference Scene: Wake-up call for the engineering and biomedical science communities in nanomedicine. Nanomedicine (London, England). 2009 Conference Paper GET IT
ONLINE THREE-DIMENSIONAL DENDRITIC SPINES MOPHOLOGICAL CLASSIFICATION BASED ON SEMI-SUPERVISED LEARNING. Proceedings. IEEE International Symposium on Biomedical Imaging. 2009 Academic Article GET IT
Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein. Cancer cell international. 2009 Academic Article GET IT
Times cited: 24
Automated brain tumor segmentation using spatial accuracy-weighted hidden Markov Random Field. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2009 Academic Article GET IT
Times cited: 78
An automated pipeline for dendrite spine detection and tracking of 3D optical microscopy neuron images of in vivo mouse models. Neuroinformatics. 2009 Academic Article GET IT
Times cited: 37
An Image Driven Systems Biology Approach for Neurodegenerative Disease Studies in the TSC-mTOR Pathway. IEEE/NIH Life Science Systems and Applications Workshop. IEEE/NIH Life Science Systems and Applications Workshop. 2009 Academic Article GET IT
Pattern-selection based power analysis and discrimination of low- and high-grade myelodysplastic syndromes study using SNP arrays. PloS one. 2009 Academic Article GET IT
Identification of biomarkers for risk stratification of cardiovascular events using genetic algorithm with recursive local floating search. Proteomics. 2009 Academic Article GET IT
Times cited: 6
Online Phenotype Discovery based on Minimum Classification Error Model. Pattern recognition. 2009 Academic Article GET IT
Introduction to the special issue of "Advances in Molecular Imaging". European journal of radiology. 2009 Editorial Article GET IT
A novel cell segmentation method and cell phase identification using Markov model. IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society. 2009 Academic Article GET IT
Times cited: 69
Improved residue function and reduced flow dependence in MR perfusion using least-absolute-deviation regularization. Magnetic resonance in medicine. 2009 Academic Article GET IT
Times cited: 10
INTEGRATING MULTI-SCALE BLOB/CURVILINEAR DETECTOR TECHNIQUES AND MULTI-LEVEL SETS FOR AUTOMATED SEGMENTATION OF STEM CELL IMAGES. Proceedings. IEEE International Symposium on Biomedical Imaging. 2009 Academic Article GET IT
Multiple distinct clones may co-exist in different lineages in myelodysplastic syndromes. Leukemia research. 2008 Academic Article GET IT
Times cited: 9
Conditional random pattern algorithm for LOH inference and segmentation. Bioinformatics (Oxford, England). 2008 Academic Article GET IT
Times cited: 6
A confident scale-space shape representation framework for cell migration detection. Journal of microscopy. 2008 Academic Article GET IT
Times cited: 3
A quantitative study of factors affecting in vivo bioluminescence imaging. Luminescence : the journal of biological and chemical luminescence. 2008 Academic Article GET IT
Times cited: 32
Computational prediction models for early detection of risk of cardiovascular events using mass spectrometry data. IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society. 2008 Academic Article GET IT
Times cited: 15
Registration of 3-D CT and 2-D flat images of mouse via affine transformation. IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society. 2008 Academic Article GET IT
Times cited: 20
3D Axon structure extraction and analysis in confocal fluorescence microscopy images. Neural computation. 2008 Academic Article GET IT
Times cited: 16
Computational Systems Bioinformatics and Bioimaging for Pathway Analysis and Drug Screening. Proceedings of the IEEE. Institute of Electrical and Electronics Engineers. 2008 Academic Article GET IT
The knowledge-integrated network biomarkers discovery for major adverse cardiac events. Journal of proteome research. 2008 Academic Article GET IT
Times cited: 61
Robust 3D reconstruction and identification of dendritic spines from optical microscopy imaging. Medical image analysis. 2008 Academic Article GET IT
Times cited: 50
Reversible jump MCMC approach for peak identification for stroke SELDI mass spectrometry using mixture model. Bioinformatics (Oxford, England). 2008 Academic Article GET IT
Times cited: 16
Segmentation of touching cell nuclei using gradient flow tracking. Journal of microscopy. 2008 Academic Article GET IT
Times cited: 53
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens. BMC bioinformatics. 2008 Academic Article GET IT
Times cited: 39
MeCP2, a key contributor to neurological disease, activates and represses transcription. Science (New York, N.Y.). 2008 Academic Article GET IT
Times cited: 1481
Workflow and methods of high-content time-lapse analysis for quantifying intracellular calcium signals. Neuroinformatics. 2008 Academic Article GET IT
Times cited: 3
An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling. Journal of biomedical informatics. 2008 Academic Article GET IT
Times cited: 14
MR analysis of regional brain volume in adolescent idiopathic scoliosis: neurological manifestation of a systemic disease. Journal of magnetic resonance imaging : JMRI. 2008 Academic Article GET IT
Times cited: 42
Using nonlinear diffusion and mean shift to detect and connect cross-sections of axons in 3D optical microscopy images. Medical image analysis. 2008 Academic Article GET IT
Times cited: 23
First-pass myocardial perfusion image registration by maximization of normalized mutual information. Journal of magnetic resonance imaging : JMRI. 2008 Academic Article GET IT
Times cited: 16
Automatic segmentation of high-throughput RNAi fluorescent cellular images. IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society. 2008 Academic Article GET IT
Times cited: 145
Cellular phenotype recognition for high-content RNA interference genome-wide screening. Journal of biomolecular screening. 2008 Academic Article GET IT
Times cited: 53
Comparison of Bayesian and regression models in missing enzyme identification. International journal of bioinformatics research and applications. 2008 Academic Article GET IT
Times cited: 1
Progress of engineered antibody-targeted molecular imaging for solid tumors (Review). Molecular medicine reports. 2008 Academic Article GET IT
Reconstruction of central cortical surface from brain MRI images: method and application. NeuroImage. 2007 Academic Article GET IT
Times cited: 71
ZFIQ: a software package for zebrafish biology. Bioinformatics (Oxford, England). 2007 Academic Article GET IT
Times cited: 20
A structural basis for reading fluency: white matter defects in a genetic brain malformation. Neurology. 2007 Academic Article GET IT
Least-square conformal brain mapping with spring energy. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2007 Academic Article GET IT
Times cited: 6
Neuroimaging predictors of cognitive impairment in confluent white matter lesion: volumetric analyses of 99 brain regions. Dementia and geriatric cognitive disorders. 2007 Academic Article GET IT
Times cited: 20
Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy. Bioinformatics (Oxford, England). 2007 Academic Article GET IT
Times cited: 105
High content image analysis for human H4 neuroglioma cells exposed to CuO nanoparticles. BMC biotechnology. 2007 Academic Article GET IT
Times cited: 43
Automatic dendritic spine analysis in two-photon laser scanning microscopy images. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2007 Academic Article GET IT
Times cited: 27
Detection of blob objects in microscopic zebrafish images based on gradient vector diffusion. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2007 Academic Article GET IT
Times cited: 27
Chemically-selective imaging of brain structures with CARS microscopy. Optics express. 2007 Academic Article GET IT
Comparison of reversible-jump Markov-chain-Monte-Carlo learning approach with other methods for missing enzyme identification. Journal of biomedical informatics. 2007 Academic Article GET IT
Times cited: 5
3D cell nuclei segmentation based on gradient flow tracking. BMC cell biology. 2007 Academic Article GET IT
Times cited: 131
Detection of molecular particles in live cells via machine learning. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2007 Academic Article GET IT
Times cited: 34
Tracking molecular particles in live cells using fuzzy rule-based system. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2007 Academic Article GET IT
Times cited: 9
Brain tissue segmentation based on DTI data. NeuroImage. 2007 Academic Article GET IT
Times cited: 131
A novel computational approach for automatic dendrite spines detection in two-photon laser scan microscopy. Journal of neuroscience methods. 2007 Academic Article GET IT
Times cited: 58
An automated feedback system with the hybrid model of scoring and classification for solving over-segmentation problems in RNAi high content screening. Journal of microscopy. 2007 Academic Article GET IT
Times cited: 25
Characteristic of hypothalamic kisspeptin expression in the pubertal development of precocious female rats. Neuroscience letters. 2007 Academic Article GET IT
Times cited: 9
Dendritic spine detection using curvilinear structure detector and LDA classifier. NeuroImage. 2007 Academic Article GET IT
Times cited: 48
Molecular imaging programs in the United States: results of a national survey. Academic radiology. 2007 Academic Article GET IT
Times cited: 2
Context based mixture model for cell phase identification in automated fluorescence microscopy. BMC bioinformatics. 2007 Academic Article GET IT
Times cited: 32
Automated neurite extraction using dynamic programming for high-throughput screening of neuron-based assays. NeuroImage. 2007 Academic Article GET IT
Times cited: 38
Automated axon tracking of 3D confocal laser scanning microscopy images using guided probabilistic region merging. Neuroinformatics. 2007 Academic Article GET IT
Times cited: 13
A novel tracing algorithm for high throughput imaging Screening of neuron-based assays. Journal of neuroscience methods. 2006 Academic Article GET IT
Times cited: 54
Creutzfeldt-jakob disease involvement of rolandic cortex: a quantitative apparent diffusion coefficient evaluation. AJNR. American journal of neuroradiology. 2006 Academic Article GET IT
Times cited: 29
Repulsive force based snake model to segment and track neuronal axons in 3D microscopy image stacks. NeuroImage. 2006 Academic Article GET IT
Times cited: 45
Automated neurite labeling and analysis in fluorescence microscopy images. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2006 Academic Article GET IT
Times cited: 63
Automated segmentation, classification, and tracking of cancer cell nuclei in time-lapse microscopy. IEEE transactions on bio-medical engineering. 2006 Academic Article GET IT
Times cited: 271
Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss. Journal of neurochemistry. 2006 Academic Article GET IT
Times cited: 95
Protein structure similarity from Principle Component Correlation analysis. BMC bioinformatics. 2006 Academic Article GET IT
Times cited: 23
76-space analysis of grey matter diffusivity: methods and applications. NeuroImage. 2006 Academic Article GET IT
Times cited: 45
Bayesian variable selection for gene expression modeling with regulatory motif binding sites in neuroinflammatory events. Neuroinformatics. 2006 Academic Article GET IT
Times cited: 3
Mutual information-based feature selection in studying perturbation of dendritic structure caused by TSC2 inactivation. Neuroinformatics. 2006 Academic Article GET IT
Times cited: 11
Boosting alternating decision trees modeling of disease trait information. BMC genetics. 2005 Academic Article GET IT
Times cited: 24
Computerized image analysis for quantitative neuronal phenotyping in zebrafish. Journal of neuroscience methods. 2005 Academic Article GET IT
Times cited: 33
Parameters selection in gene selection using Gaussian kernel support vector machines by genetic algorithm. Journal of Zhejiang University. Science. B. 2005 Academic Article GET IT
Times cited: 30
Limitations of Wada memory asymmetry as a predictor of outcomes after temporal lobectomy. Neurology. 2005 Academic Article GET IT
Times cited: 46
Image segmentation feature selection and pattern classification for mammographic microcalcifications. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2005 Academic Article GET IT
Times cited: 99
Multiclass cancer classification by using fuzzy support vector machine and binary decision tree with gene selection. Journal of biomedicine & biotechnology. 2005 Academic Article GET IT
A computerized cellular imaging system for high content analysis in Monastrol suppressor screens. Journal of biomedical informatics. 2005 Academic Article GET IT
Times cited: 40
Diffusion-weighted and fluid-attenuated inversion recovery imaging in Creutzfeldt-Jakob disease: high sensitivity and specificity for diagnosis. AJNR. American journal of neuroradiology. 2005 Academic Article GET IT
Times cited: 278
DBMap: a space-conscious data visualization and knowledge discovery framework for biomedical data warehouse. IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society. 2004 Academic Article GET IT
Times cited: 5
Cancer classification and prediction using logistic regression with Bayesian gene selection. Journal of biomedical informatics. 2004 Academic Article GET IT
Times cited: 96
A neuroinformatics database system for disease-oriented neuroimaging research. Academic radiology. 2004 Academic Article GET IT
Times cited: 19
A web-based federated neuroinformatics model for surgical planning and clinical research applications in epilepsy. Neuroinformatics. 2004 Academic Article GET IT
Times cited: 3
An XML message broker framework for exchange and integration of microarray data. Bioinformatics (Oxford, England). 2003 Academic Article GET IT
Times cited: 4
Workflow-enabled distributed component-based information architecture for digital medical imaging enterprises. IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society. 2003 Academic Article GET IT
Times cited: 22
Towards effective and rewarding data sharing. Neuroinformatics. 2003 Academic Article GET IT
Times cited: 66
De-noising of left ventricular myocardial borders in magnetic resonance images. Magnetic resonance imaging. 2002 Academic Article GET IT
Times cited: 4
Design and applications of a multimodality image data warehouse framework. Journal of the American Medical Informatics Association : JAMIA. 2002 Academic Article GET IT
Times cited: 35
In vivo hippocampal glucose metabolism in mesial temporal lobe epilepsy. Neurology. 2001 Academic Article GET IT
Times cited: 56
Human Brain Program Research Progress in biomedical imaging/neuroscience, 2001. Journal of the American Medical Informatics Association : JAMIA. 2001 Article GET IT
Times cited: 3
Human brain program research progress in bioinformatics/ neuroinformatics. Journal of the American Medical Informatics Association : JAMIA. 2001 Editorial Article GET IT
Times cited: 8
Wavelet-based enhancement for detection of left ventricular myocardial boundaries in magnetic resonance images. Magnetic resonance imaging. 2000 Academic Article GET IT
Times cited: 25
Wavelet-based histogram equalization enhancement of gastric sonogram images. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 2000 Academic Article GET IT
Security for the digital information age of medicine: issues, applications, and implementation. Journal of digital imaging. 1998 Academic Article GET IT
Times cited: 25
Presurgical multimodality neuroimaging in electroencephalographic lateralized temporal lobe epilepsy. Annals of neurology. 1997 Academic Article GET IT
Times cited: 146
Magnetoencephalography in partial epilepsy: clinical yield and localization accuracy. Annals of neurology. 1997 Academic Article GET IT
Times cited: 212
A cryptologic based trust center for medical images. Journal of the American Medical Informatics Association : JAMIA. 1996 Academic Article GET IT
Times cited: 18
Design methods and architectural issues of integrated medical image data base systems. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. 1996 Academic Article GET IT
Times cited: 28
A paradigm for computer-assisted radiology resident rotation scheduling. Academic radiology. 1995 Academic Article GET IT
Times cited: 1

VIVO Weill Cornell Medical College

Stephen Wong Professor of Computer Science and Bioengineering in Radiology

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