selected publications
- A triple hormone receptor ER, AR, and VDR signature is a robust prognosis predictor in breast cancer. Breast cancer research : BCR. 2024 Academic Article GET IT
- HPV-YAP1 oncogenic alliance drives malignant transformation of fallopian tube epithelial cells. EMBO reports. 2024 Academic Article GET IT
- C-terminally phosphorylated p27 activates self-renewal driver genes to program cancer stem cell expansion, mammary hyperplasia and cancer. Nature communications. 2024 Academic Article GET IT
- Cell-of-Origin Targeted Drug Repurposing for Triple-Negative and Inflammatory Breast Carcinoma with HDAC and HSP90 Inhibitors Combined with Niclosamide. Cancers. 2023 Academic Article GET IT
- Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis. Cell reports. 2022 Academic Article GET IT
- ZNF92, an unexplored transcription factor with remarkably distinct breast cancer over-expression associated with prognosis and cell-of-origin. NPJ breast cancer. 2022 Academic Article GET IT
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Targeting BET Proteins BRD2 and BRD3 in Combination with PI3K-AKT Inhibition as a Therapeutic Strategy for Ovarian Clear Cell Carcinoma.
Molecular cancer therapeutics.
2021
Academic Article
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Times cited: 21 -
Transient commensal clonal interactions can drive tumor metastasis.
Nature communications.
2020
Academic Article
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Times cited: 30 - Micron scale electromagnetic viable tumor cell capture and release. Microfluidics and Nanofluidics. 2020 Article GET IT
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BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer.
EBioMedicine.
2020
Academic Article
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Times cited: 27 -
The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development.
Cell metabolism.
2020
Academic Article
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Times cited: 13 -
HDAC7 regulates histone 3 lysine 27 acetylation and transcriptional activity at super-enhancer-associated genes in breast cancer stem cells.
Oncogene.
2019
Academic Article
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Times cited: 22 -
Ovarian Cancer Treatment Stratification Using Ex Vivo Drug Sensitivity Testing.
Anticancer research.
2019
Academic Article
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Times cited: 11 - Mutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition. JCI Insight. 2019 Article GET IT
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Dual Src and MEK Inhibition Decreases Ovarian Cancer Growth and Targets Tumor Initiating Stem-Like Cells.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018
Academic Article
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Times cited: 56 -
Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma.
Proceedings of the National Academy of Sciences of the United States of America.
2017
Academic Article
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Times cited: 104 -
VEGFA activates an epigenetic pathway upregulating ovarian cancer-initiating cells.
EMBO molecular medicine.
2017
Academic Article
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Times cited: 58 - Rare Cell Immobilization on MEMS Scale Sensors Using Micro-Electromagnets. IEEE Sensors Journal. 2016 Article GET IT
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Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer.
Oncogene.
2016
Academic Article
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Times cited: 136 -
Reference-free deconvolution of DNA methylation data and mediation by cell composition effects.
BMC bioinformatics.
2016
Academic Article
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Times cited: 176 -
Breast cancers from black women exhibit higher numbers of immunosuppressive macrophages with proliferative activity and of crown-like structures associated with lower survival compared to non-black Latinas and Caucasians.
Breast cancer research and treatment.
2016
Academic Article
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Times cited: 90 -
Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer.
Breast cancer research and treatment.
2016
Academic Article
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Times cited: 58 -
Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b-Mediated Malignant Progression.
Cancer research.
2016
Academic Article
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Times cited: 91 -
MAPK Activation Predicts Poor Outcome and the MEK Inhibitor, Selumetinib, Reverses Antiestrogen Resistance in ER-Positive High-Grade Serous Ovarian Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2015
Academic Article
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Times cited: 54 -
Of mice and women: a comparative tissue biology perspective of breast stem cells and differentiation.
Journal of mammary gland biology and neoplasia.
2015
Information Resource
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Times cited: 51 -
Heat shock factor 1 induces cancer stem cell phenotype in breast cancer cell lines.
Breast cancer research and treatment.
2015
Academic Article
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Times cited: 37 -
Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours.
Nature communications.
2015
Academic Article
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Times cited: 144 -
Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation.
Oncogene.
2015
Academic Article
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Times cited: 99 -
Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells.
Oncogene.
2014
Academic Article
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Times cited: 21 -
Mesenchymal gene program-expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance.
The Journal of clinical investigation.
2014
Academic Article
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Times cited: 111 -
Taxonomy of breast cancer based on normal cell phenotype predicts outcome.
The Journal of clinical investigation.
2014
Academic Article
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Times cited: 158 -
Rb suppresses collective invasion, circulation and metastasis of breast cancer cells in CD44-dependent manner.
PloS one.
2013
Academic Article
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Times cited: 18 -
Gene expression signature of normal cell-of-origin predicts ovarian tumor outcomes.
PloS one.
2013
Academic Article
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Times cited: 39 -
A genome-wide siRNA screen identifies proteasome addiction as a vulnerability of basal-like triple-negative breast cancer cells.
Cancer cell.
2013
Academic Article
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Times cited: 139 -
Chaperone-mediated autophagy degrades mutant p53.
Genes & development.
2013
Academic Article
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Times cited: 172 -
PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy.
Breast cancer research and treatment.
2013
Academic Article
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Times cited: 45 -
Retraction. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis.
Cancer cell.
2013
Article
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Times cited: 1 -
Defined, serum-free conditions for in vitro culture of primary human T-ALL blasts.
Leukemia.
2012
Article
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Times cited: 14 -
Src Inhibition with saracatinib reverses fulvestrant resistance in ER-positive ovarian cancer models in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2012
Academic Article
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Times cited: 57 -
HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers.
Cell.
2012
Academic Article
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Times cited: 538 -
Reproducibility of endometrial intraepithelial neoplasia diagnosis is good, but influenced by the diagnostic style of pathologists.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2012
Academic Article
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Times cited: 21 -
High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer.
Proceedings of the National Academy of Sciences of the United States of America.
2011
Academic Article
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Times cited: 244 -
Ovarian cancer spheroids use myosin-generated force to clear the mesothelium.
Cancer discovery.
2011
Academic Article
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Times cited: 244 -
Differentiation of NUT midline carcinoma by epigenomic reprogramming.
Cancer research.
2011
Academic Article
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Times cited: 181 -
Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective.
Histopathology.
2009
Article
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Times cited: 20 -
Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells.
Nature biotechnology.
2009
Academic Article
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Times cited: 386 -
Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2009
Academic Article
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Times cited: 253 -
Squamous morules are functionally inert elements of premalignant endometrial neoplasia.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2008
Academic Article
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Times cited: 46 -
Do-it-yourself (DIY) pathology.
Nature biotechnology.
2008
Article
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Times cited: 30 -
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression.
Cell.
2008
Academic Article
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Times cited: 369 -
Systemic endocrine instigation of indolent tumor growth requires osteopontin.
Cell.
2008
Academic Article
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Times cited: 363 -
Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective.
Histopathology.
2008
Information Resource
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Times cited: 82 -
Human embryonic stem cell derivation from poor-quality embryos.
Nature biotechnology.
2008
Academic Article
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Times cited: 80 -
Reprogramming of human somatic cells to pluripotency with defined factors.
Nature.
2007
Academic Article
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Times cited: 2274 -
Over 60% of NIH extramural funding involves animal-related research.
Veterinary pathology.
2007
Article
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Times cited: 14 -
The terminology of teratocarcinomas and teratomas.
Nature biotechnology.
2007
Article
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Times cited: 31 -
Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes.
Cancer cell.
2007
Academic Article
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Times cited: 244 -
From whence will they come? - A perspective on the acute shortage of pathologists in biomedical research.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
2007
Article
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Times cited: 24 -
The distal fallopian tube: a new model for pelvic serous carcinogenesis.
Current opinion in obstetrics & gynecology.
2007
Information Resource
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Times cited: 349 - I enjoyed the article about reserve cells. Human pathology. 2005 Letter GET IT
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Prediction of endometrial carcinoma by subjective endometrial intraepithelial neoplasia diagnosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.
2005
Academic Article
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Times cited: 128 -
Microglandular hyperplasia: a model for the de novo emergence and evolution of endocervical reserve cells.
Human pathology.
2005
Academic Article
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Times cited: 29 -
Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer.
Nature medicine.
2004
Academic Article
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Times cited: 470 -
Uterine leiomyomata with t(10;17) disrupt the histone acetyltransferase MORF.
Cancer research.
2004
Academic Article
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Times cited: 78 - Telomerase: promise and challenge. Human pathology. 2004 Editorial Article GET IT
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Biomarkers in diagnostic obstetric and gynecologic pathology: a review.
Advances in anatomic pathology.
2003
Information Resource
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Times cited: 39 -
Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis.
Cancer cell.
2003
Academic Article
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Times cited: 280 -
Loss of p63 expression is associated with tumor progression in bladder cancer.
The American journal of pathology.
2002
Academic Article
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Times cited: 232 -
p63 Coordinates anogenital modeling and epithelial cell differentiation in the developing female urogenital tract.
The American journal of pathology.
2002
Academic Article
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Times cited: 91 -
Functional genomics and the breast cancer problem.
Cancer cell.
2002
Information Resource
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Times cited: 18 -
Optimization of a versatile in vitro transcription assay for the expression of multiple start site TATA-less promoters.
Biochemistry.
2001
Academic Article
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Times cited: 12 -
Molecular identification of latent precancers in histologically normal endometrium.
Cancer research.
2001
Academic Article
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Times cited: 181 -
Transcriptional repression by p53 through direct binding to a novel DNA element.
The Journal of biological chemistry.
2001
Academic Article
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Times cited: 129 -
Surrogate biomarkers of HPV infection in cervical neoplasia screening and diagnosis.
Advances in anatomic pathology.
2001
Information Resource
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Times cited: 94 -
Stable transfection of the P-glycoprotein promoter reproduces the endogenous overexpression phenotype: the role of MED-1.
Cancer research.
1996
Academic Article
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Times cited: 16 -
A conserved downstream element defines a new class of RNA polymerase II promoters.
The Journal of biological chemistry.
1995
Academic Article
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Times cited: 137 -
Differential utilization of multiple transcription start points accompanies the overexpression of the P-glycoprotein-encoding gene in Chinese hamster lung cells.
Gene.
1995
Academic Article
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Times cited: 25