Lu, Theresa T.

Publications

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Langerhans cells regulate immunity in adulthood by regulating postnatal dermal lymphatic development. 2024 GET IT
The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus. eLife. 2024 Academic Article GET IT
Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load. Cell reports. 2024 Academic Article GET IT
Nogo-A reduces ceramide de novo biosynthesis to protect from heart failure. Cardiovascular research. 2022 Academic Article GET IT
Mammalian Target of Rapamycin Pathway Assessment in Antiphospholipid Antibody Positive Patients with Livedo. The Journal of rheumatology. 2022 Academic Article GET IT
Mammalian Target of Rapamycin Pathway Assessment in Antiphospholipid Antibody Positive Patients with Livedo. The Journal of rheumatology. 2022 Academic Article
Advances in understanding and examining lymphatic function: relevance for understanding autoimmunity. Current opinion in rheumatology. 2021 Information Resource GET IT
Advances in understanding and examining lymphatic function: relevance for understanding autoimmunity. Current opinion in rheumatology. 2021 Information Resource GET IT
Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Science signaling. 2021 Academic Article GET IT
Times cited: 14
Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype. The Journal of biological chemistry. 2021 Academic Article GET IT
Times cited: 7
Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype. The Journal of biological chemistry. 2021 Academic Article GET IT
Times cited: 7
Immune Cell-Stromal Circuitry in Lupus Photosensitivity. Journal of immunology (Baltimore, Md. : 1950). 2021 Information Resource GET IT
Immune Cell-Stromal Circuitry in Lupus Photosensitivity. Journal of immunology (Baltimore, Md. : 1950). 2021 Information Resource GET IT
T2B or not to B: Calming neutrophils offshore. 2021 Editorial Article
Fibroblast subtypes in tissues affected by autoimmunity: with lessons from lymph node fibroblasts. Current opinion in immunology. 2020 Information Resource GET IT
Times cited: 4
Lymph node stromal CCL2 limits antibody responses. Science immunology. 2020 Academic Article GET IT
Times cited: 24
Adaptive and innate immune cell responses in tendons and lymph nodes after tendon injury and repair. Journal of applied physiology (Bethesda, Md. : 1985). 2020 Academic Article GET IT
Times cited: 20
Disruption of the Gut Microbiome Increases the Risk of Periprosthetic Joint Infection in Mice. Clinical orthopaedics and related research. 2019 Academic Article GET IT
Times cited: 33
Role of type I interferons and innate immunity in systemic sclerosis: unbalanced activities on distinct cell types?. Current opinion in rheumatology. 2019 Information Resource GET IT
Times cited: 11
The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair. Immunity. 2019 Academic Article GET IT
Times cited: 99
Immunopathogenesis of Juvenile Systemic Sclerosis. Frontiers in immunology. 2019 Information Resource GET IT
Times cited: 24
Immunopathogenesis of Pediatric Localized Scleroderma. Frontiers in immunology. 2019 Information Resource GET IT
Times cited: 61
Lymphatic Function in Autoimmune Diseases. Frontiers in immunology. 2019 Information Resource GET IT
Times cited: 32
A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity. Science translational medicine. 2018 Academic Article GET IT
Times cited: 47
The roles of dermal white adipose tissue loss in scleroderma skin fibrosis. Current opinion in rheumatology. 2017 Information Resource GET IT
Times cited: 15
Tertiary lymphoid organs in systemic autoimmune diseases: pathogenic or protective?. F1000Research. 2017 Information Resource GET IT
Times cited: 27
Dendritic cells maintain dermal adipose-derived stromal cells in skin fibrosis. The Journal of clinical investigation. 2016 Academic Article GET IT
Times cited: 40
Regulation of Lymph Node Vascular-Stromal Compartment by Dendritic Cells. Trends in immunology. 2016 Information Resource GET IT
Times cited: 21
Update on macrophages and innate immunity in scleroderma. Current opinion in rheumatology. 2015 Information Resource GET IT
Times cited: 36
A dendritic-cell-stromal axis maintains immune responses in lymph nodes. Immunity. 2015 Academic Article GET IT
Times cited: 69
Multiple CD11c+ cells collaboratively express IL-1β to modulate stromal vascular endothelial growth factor and lymph node vascular-stromal growth. Journal of immunology (Baltimore, Md. : 1950). 2014 Academic Article GET IT
Times cited: 33
Role of the Lymphotoxin/LIGHT System in the Development and Maintenance of Reticular Networks and Vasculature in Lymphoid Tissues. Frontiers in immunology. 2014 Information Resource GET IT
Times cited: 71
Optical projection tomography reveals dynamics of HEV growth after immunization with protein plus CFA and features shared with HEVs in acute autoinflammatory lymphadenopathy. Frontiers in immunology. 2012 Academic Article GET IT
Times cited: 42
Lymph node vascular-stromal growth and function as a potential target for controlling immunity. Clinical immunology (Orlando, Fla.). 2012 Information Resource GET IT
Times cited: 13
Normalization of the lymph node T cell stromal microenvironment in lpr/lpr mice is associated with SU5416-induced reduction in autoantibodies. PloS one. 2012 Academic Article GET IT
Times cited: 8
Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity. The Journal of experimental medicine. 2012 Academic Article GET IT
Times cited: 57
Dendritic cells: novel players in fibrosis and scleroderma. Current rheumatology reports. 2012 Information Resource GET IT
Times cited: 33
Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells. Journal of immunology (Baltimore, Md. : 1950). 2011 Academic Article GET IT
Times cited: 102
IL-17, a new kid on the block of tertiary lymphoid organs. Cellular & molecular immunology. 2011 Article GET IT
Times cited: 2
Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth. Journal of the National Cancer Institute. 2010 Academic Article GET IT
Times cited: 55
CD11c(hi) dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes. Journal of immunology (Baltimore, Md. : 1950). 2010 Academic Article GET IT
Times cited: 37
Overlap between systemic lupus erythematosus and Kikuchi Fujimoto disease: a clinical pathology conference held by the Department of Rheumatology at Hospital for Special Surgery. HSS journal : the musculoskeletal journal of Hospital for Special Surgery. 2009 Conference Paper GET IT
Times cited: 16
Fibroblast-type reticular stromal cells regulate the lymph node vasculature. Journal of immunology (Baltimore, Md. : 1950). 2008 Academic Article GET IT
Times cited: 112
Regulation of lymph node vascular growth by dendritic cells. The Journal of experimental medicine. 2006 Academic Article GET IT
Times cited: 163
IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity. 2006 Academic Article GET IT
Times cited: 290
Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells. Immunity. 2005 Academic Article GET IT
Times cited: 246
Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone. Nature immunology. 2004 Academic Article GET IT
Times cited: 324
Integrin-dependence of lymphocyte entry into the splenic white pulp. The Journal of experimental medicine. 2003 Academic Article GET IT
Times cited: 142
Integrin-mediated long-term B cell retention in the splenic marginal zone. Science (New York, N.Y.). 2002 Academic Article GET IT
Times cited: 307
A coordinated change in chemokine responsiveness guides plasma cell movements. The Journal of experimental medicine. 2001 Academic Article GET IT
Times cited: 540
Discontinuation of methotrexate treatment in juvenile rheumatoid arthritis. Pediatrics. 1997 Academic Article GET IT
Times cited: 55
Platelet endothelial cell adhesion molecule-1 is phosphorylatable by c-Src, binds Src-Src homology 2 domain, and exhibits immunoreceptor tyrosine-based activation motif-like properties. The Journal of biological chemistry. 1997 Academic Article GET IT
Times cited: 89
Platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) tyrosine phosphorylation state changes during vasculogenesis in the murine conceptus. The American journal of pathology. 1997 Academic Article GET IT
Times cited: 64
Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1. Proceedings of the National Academy of Sciences of the United States of America. 1996 Academic Article GET IT
Times cited: 99
Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Academic Article
Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Academic Article
Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Academic Article
Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Academic Article
Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Academic Article
Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype. Academic Article
Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype. Academic Article
T2B or not to B: Calming neutrophils offshore. Editorial Article
T2B or not to B: Calming neutrophils offshore. Editorial Article
T2B or not to B: Calming neutrophils offshore. Editorial Article

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Background

education and training

M.D., Ph.D., Yale University School of Medicine , PhD in Lab of Joseph Madri 1988 - 1995
M.D., Ph.D., Yale University School of Medicine 1995
B.S., Yale University 1988
Children's Hospital of Philadelphia , Residency in Pediatrics 1995 - 1998
University of California, San Francisco , Postdoc, lab of Jason Cyster 2000 - 2003
University of California, San Francisco , Fellowship in Pediatric Rheumatology 1999 - 2003

Contact

full name

Theresa T. Lu

primary email

thl2005@med.cornell.edu

webpage

https://www.hss.edu/research-staff_lu-theresa.asp
https://www.theresalulab.com/

VIVO Weill Cornell Medical College

Theresa T. Lu Professor of Microbiology and Immunology

Publications

selected publications

Background

education and training

Contact

full name

primary email

webpage