Eagar, Todd

Publications

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selected publications

Treatment of Coronavirus Disease 2019 (COVID-19) Patients with Convalescent Plasma. The American journal of pathology. 2020 Academic Article GET IT
Times cited: 192
Population Genomic Analysis of 1,777 Extended-Spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Isolates, Houston, Texas: Unexpected Abundance of Clonal Group 307. mBio. 2017 Academic Article GET IT
Times cited: 87
A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB1*03:01 by a Murine TCR. PloS one. 2016 Academic Article GET IT
Times cited: 6
T cell subsets and their signature cytokines in autoimmune and inflammatory diseases. Cytokine. 2014 Information Resource GET IT
Times cited: 743
Testing effects of glatiramer acetate and fingolimod in an infectious model of CNS immune surveillance. Journal of neuroimmunology. 2014 Academic Article GET IT
Immune surveillance of the central nervous system in multiple sclerosis--relevance for therapy and experimental models. Journal of neuroimmunology. 2014 Information Resource GET IT
Times cited: 25
A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease. Journal of neuroimmunology. 2012 Academic Article GET IT
Times cited: 28
Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet. Journal of neuroinflammation. 2011 Academic Article GET IT
Times cited: 32
DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation. Cellular and molecular neurobiology. 2011 Academic Article GET IT
Times cited: 40
Rituximab therapy reduces organ-specific T cell responses and ameliorates experimental autoimmune encephalomyelitis. PloS one. 2011 Academic Article GET IT
Times cited: 70
Memory B cells from a subset of treatment-naïve relapsing-remitting multiple sclerosis patients elicit CD4(+) T-cell proliferation and IFN-γ production in response to myelin basic protein and myelin oligodendrocyte glycoprotein. European journal of immunology. 2010 Academic Article GET IT
Times cited: 97
Reversible alopecia associated with glatiramer acetate. Archives of neurology. 2010 Article GET IT
Times cited: 4
Translational research in neurology and neuroscience 2010: multiple sclerosis. Archives of neurology. 2010 Information Resource GET IT
Times cited: 14
Analysis of three plasmid systems for use in DNA A beta 42 immunization as therapy for Alzheimer's disease. Vaccine. 2010 Academic Article GET IT
Times cited: 30
Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling. Brain : a journal of neurology. 2010 Academic Article GET IT
Times cited: 29
DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model. JAMA. 2009 Academic Article GET IT
Times cited: 47
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nature immunology. 2009 Academic Article GET IT
Times cited: 604
Direct and consensual murine pupillary reflex metrics: establishing normative values. Autonomic neuroscience : basic & clinical. 2009 Academic Article GET IT
Times cited: 20
200 years after Darwin. JAMA. 2009 Academic Article GET IT
200 years after Darwin. Archives of neurology. 2009 Editorial Article GET IT
Times cited: 1
PEG minocycline-liposomes ameliorate CNS autoimmune disease. PloS one. 2009 Academic Article GET IT
Times cited: 46
Immunologic mechanisms of multiple sclerosis. Neuroimaging clinics of North America. 2008 Information Resource GET IT
Times cited: 21
Quinpramine is a novel compound effective in ameliorating brain autoimmune disease. Experimental neurology. 2008 Academic Article GET IT
Times cited: 11
Decrease in the numbers of dendritic cells and CD4+ T cells in cerebral perivascular spaces due to natalizumab. Archives of neurology. 2008 Academic Article GET IT
Times cited: 117
DNA-based vaccines: the future of multiple sclerosis therapy?. Expert review of neurotherapeutics. 2008 Information Resource GET IT
Times cited: 10
DNA plasmid vaccination for multiple sclerosis. Archives of neurology. 2007 Editorial Article GET IT
Times cited: 5
Prion proteins: physiological functions and role in neurological disorders. Journal of the neurological sciences. 2007 Information Resource GET IT
Times cited: 29
Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway. The Journal of experimental medicine. 2006 Academic Article GET IT
Times cited: 263
Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 2005 Academic Article GET IT
Times cited: 81
CTLA-4 regulates expansion and differentiation of Th1 cells following induction of peripheral T cell tolerance. Journal of immunology (Baltimore, Md. : 1950). 2004 Academic Article GET IT
Times cited: 27
Notch 1 signaling regulates peripheral T cell activation. Immunity. 2004 Academic Article GET IT
Times cited: 128
Functional activation of myelin-specific T cells by virus-induced molecular mimicry. Journal of immunology (Baltimore, Md. : 1950). 2002 Academic Article GET IT
Times cited: 52
The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance. European journal of immunology. 2002 Academic Article GET IT
Times cited: 92
Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis. The Journal of clinical investigation. 2001 Academic Article GET IT
Times cited: 111
CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitis. Journal of neuroimmunology. 2000 Academic Article GET IT
Times cited: 47
Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). 2000 Academic Article GET IT
Times cited: 172
Tissue-specific up-regulation of B7-1 expression and function during the course of murine relapsing experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). 1998 Academic Article GET IT
Times cited: 59
Activation of antigen-specific T cells in vivo induced by tolerogenic encounter with antigen-coupled splenocytes. FASEB Journal. 1998 Article

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Background

education and training

Ph.D., Northwestern University Medical School 2002
B.S., Brigham Young University 1993

Contact

full name

Todd Eagar

VIVO Weill Cornell Medical College

Todd Eagar Assistant Professor of Pathology and Laboratory Medicine

Publications

selected publications

Background

education and training

Contact

full name