Jiang, Xiuju

Publications

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selected publications

Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB. PLoS pathogens. 2020 Academic Article GET IT
Times cited: 9
Evidence for dispensability of protein kinase R in host control of tuberculosis. European journal of immunology. 2018 Academic Article GET IT
Times cited: 8
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. ACS infectious diseases. 2018 Academic Article GET IT
Times cited: 18
Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes. Nature communications. 2017 Academic Article GET IT
Times cited: 46
Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT
Times cited: 60
Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome. ACS infectious diseases. 2016 Academic Article GET IT
Times cited: 21
Immunoproteasome β5i-Selective Dipeptidomimetic Inhibitors. ChemMedChem. 2016 Academic Article GET IT
Times cited: 28
Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis. PloS one. 2015 Academic Article GET IT
Times cited: 18
Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells. Cell host & microbe. 2015 Academic Article GET IT
Times cited: 85
Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis. ACS chemical biology. 2014 Academic Article GET IT
Times cited: 28
Benzimidazole-based compounds kill Mycobacterium tuberculosis. European journal of medicinal chemistry. 2014 Academic Article GET IT
Times cited: 33
Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis. PloS one. 2013 Academic Article GET IT
Times cited: 63
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. Proceedings of the National Academy of Sciences of the United States of America. 2012 Academic Article GET IT
Times cited: 94
Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R. PloS one. 2012 Academic Article GET IT
Times cited: 36
Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistance. Journal of medicinal chemistry. 2009 Academic Article GET IT
Times cited: 107
Mycobacterium tuberculosis expresses methionine sulphoxide reductases A and B that protect from killing by nitrite and hypochlorite. Molecular microbiology. 2009 Academic Article GET IT
Times cited: 68
Identification of a copper-binding metallothionein in pathogenic mycobacteria. Nature chemical biology. 2008 Academic Article GET IT
Times cited: 176
Selective killing of nonreplicating mycobacteria. Cell host & microbe. 2008 Academic Article GET IT
Times cited: 159
A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium. The Journal of cell biology. 2007 Academic Article GET IT
Times cited: 143

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Research

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Funding awarded

Studies of lipoamide dehydrogenase tight binding inhibition in tuberculous and non-tuberculous mycobacteria awarded by National Institute of Allergy & Infectious Diseases Key Personnel 2023 - 2028
Phosphopantetheinyl transferase (PptT) inhibitors for treatment of TB- INV-040480 awarded by Bill & Melinda Gates Foundation Key Personnel 2022 - 2024

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Background

education and training

M.S., Liaoning Normal University (China) 1990
B.A., Liaoning Normal University (China) 1987

Contact

full name

Xiuju Jiang

primary email

xij2002@med.cornell.edu

VIVO Weill Cornell Medical College

Xiuju Jiang Senior Research Associate in Microbiology and Immunology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email