Houvras, Yariv

Publications

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selected publications

Linvoseltamab for Treatment of Relapsed/Refractory Multiple Myeloma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2024 Academic Article GET IT
Depletion of tet2 results in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome. Frontiers in hematology. 2023 Academic Article GET IT
Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes. 2023 GET IT
Common and rare variant associations with clonal haematopoiesis phenotypes. Nature. 2022 Academic Article GET IT
Times cited: 103
A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish. Hepatology communications. 2022 Academic Article GET IT
Safety and efficacy of pralsetinib in RET fusion-positive non-small-cell lung cancer including as first-line therapy: update from the ARROW trial. Annals of oncology : official journal of the European Society for Medical Oncology. 2022 Academic Article GET IT
Times cited: 30
Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer. The Journal of experimental medicine. 2022 Academic Article GET IT
Times cited: 9
PPP6C, a serine-threonine phosphatase, regulates melanocyte differentiation and contributes to melanoma tumorigenesis through modulation of MITF activity. Scientific reports. 2022 Academic Article GET IT
RET Fusion-Positive Papillary Thyroid Cancers are Associated with a More Aggressive Phenotype. Annals of surgical oncology. 2022 Academic Article GET IT
Times cited: 7
Histone 3 Methyltransferases Alter Melanoma Initiation and Progression Through Discrete Mechanisms. Frontiers in cell and developmental biology. 2022 Academic Article GET IT
Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing. The oncologist. 2021 Academic Article GET IT
Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood. The Journal of clinical investigation. 2020 Academic Article GET IT
Times cited: 33
Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair. Nucleic acids research. 2020 Academic Article GET IT
Times cited: 28
Oxidative Phosphorylation Promotes Primary Melanoma Invasion. The American journal of pathology. 2020 Academic Article GET IT
Times cited: 15
Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. 2019 Academic Article GET IT
Times cited: 75
Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth. The EMBO journal. 2018 Academic Article GET IT
Times cited: 75
Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma. The Journal of clinical investigation. 2017 Academic Article GET IT
Times cited: 40
Identification and characterization of T reg-like cells in zebrafish. The Journal of experimental medicine. 2017 Academic Article GET IT
Times cited: 59
Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression. eLife. 2017 Academic Article GET IT
Times cited: 48
Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 2016 Academic Article GET IT
Times cited: 49
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature cell biology. 2016 Academic Article GET IT
Times cited: 167
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish. Nature communications. 2016 Academic Article GET IT
Times cited: 74
Uncharted Waters: Zebrafish Cancer Models Navigate a Course for Oncogene Discovery. 2016 GET IT
Times cited: 2
SPOP mutation leads to genomic instability in prostate cancer. eLife. 2015 Academic Article GET IT
Times cited: 144
Multiplexing of ChIP-Seq Samples in an Optimized Experimental Condition Has Minimal Impact on Peak Detection. PloS one. 2015 Academic Article GET IT
RSK1 activation promotes invasion in nodular melanoma. The American journal of pathology. 2015 Academic Article GET IT
Times cited: 23
Optimized cell transplantation using adult rag2 mutant zebrafish. Nature methods. 2014 Academic Article GET IT
Times cited: 111
Efatutazone, an oral PPAR-γ agonist, in combination with paclitaxel in anaplastic thyroid cancer: results of a multicenter phase 1 trial. The Journal of clinical endocrinology and metabolism. 2013 Academic Article GET IT
Times cited: 95
Screening for melanoma modifiers using a zebrafish autochthonous tumor model. Journal of visualized experiments : JoVE. 2012 Academic Article GET IT
Times cited: 23
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell. 2012 Academic Article GET IT
Times cited: 655
Hooked on zebrafish: insights into development and cancer of endocrine tissues. Endocrine-related cancer. 2011 Review GET IT
Times cited: 11
Cabozantinib in medullary thyroid carcinoma: time to focus the spotlight on this rare disease. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Editorial Article GET IT
Times cited: 8
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature. 2011 Academic Article GET IT
Times cited: 424
Melanoma biology and the promise of zebrafish. Zebrafish. 2008 Review GET IT
Times cited: 40
The effect of a depth gradient on the mating behavior, oviposition site preference, and embryo production in the zebrafish, Danio rerio. Zebrafish. 2008 Academic Article GET IT
Times cited: 33
BRCA1 physically and functionally interacts with ATF1. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 52
Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1. Nature. 1997 Academic Article GET IT
Times cited: 470

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Background

education and training

M.D., Mount Sinai School of Medicine 2001
Ph.D., Mount Sinai School of Medicine 2001
B.S., University of Michigan 1992

Contact

full name

Yariv Houvras

primary email

yah9014@med.cornell.edu

VIVO Weill Cornell Medical College

Yariv Houvras Clinical Associate Professor of Medicine (Courtesy)

Publications

selected publications

Background

education and training

Contact

full name

primary email