Zhu, Yuan-Shan

Publications

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selected publications

Relationship between adipokines and androgens in children and young adults with congenital adrenal hyperplasia. Frontiers in endocrinology. 2024 Academic Article GET IT
Evidence of Pericyte Damage in a Cognitively Normal Cohort: Association With CSF and PET Biomarkers of Alzheimer's Disease. Alzheimer disease and associated disorders. 2024 Academic Article GET IT
Plasma Cell-Free Mitochondrial DNA as a Marker of Geriatric Syndromes in Older Adults With HIV. Journal of acquired immune deficiency syndromes (1999). 2022 Academic Article GET IT
Times cited: 4
Pain Is Associated With Depressive Symptoms, Inflammation, and Poorer Physical Function in Older Adults With HIV. Psychosomatic medicine. 2022 Academic Article GET IT
Times cited: 7
Links Between Inflammation, Mood, and Physical Function Among Older Adults With HIV. The journals of gerontology. Series B, Psychological sciences and social sciences. 2022 Academic Article GET IT
Times cited: 10
Molecular and cellular functions of long non-coding RNAs in prostate and breast cancer. 2021 GET IT
Urine Cell-Free Mitochondrial DNA as a Marker of Weight Loss and Body Composition in Older Adults With HIV. Journal of acquired immune deficiency syndromes (1999). 2021 Academic Article GET IT
Times cited: 7
Childhood sexual abuse history amplifies the link between disease burden and inflammation among older adults with HIV. Brain, behavior, & immunity - health. 2021 Academic Article GET IT
Times cited: 4
Tumor necrosis factor-alpha is associated with mineral bone disorder and growth impairment in children with chronic kidney disease. Pediatric nephrology (Berlin, Germany). 2021 Academic Article GET IT
Times cited: 8
Carbonyl iron and iron dextran therapies cause adverse effects on bone health in juveniles with chronic kidney disease. Kidney international. 2020 Academic Article GET IT
Times cited: 12
Intestinal Dysbiosis and Markers of Systemic Inflammation in Viscerally and Generally Obese Persons Living With HIV. Journal of acquired immune deficiency syndromes (1999). 2020 Academic Article GET IT
Times cited: 13
Long non-coding RNAs in prostate cancer: Functional roles and clinical implications. Cancer letters. 2019 Information Resource GET IT
Times cited: 22
Statins induce cell apoptosis through a modulation of AKT/FOXO1 pathway in prostate cancer cells. Cancer management and research. 2019 Academic Article GET IT
Times cited: 29
LncRNA Profile Study Reveals a Three-LncRNA Signature Associated With the Pathological Complete Response Following Neoadjuvant Chemotherapy in Breast Cancer. Frontiers in pharmacology. 2019 Academic Article GET IT
Times cited: 21
Epilepsy, depression, and growth hormone. Epilepsy & behavior : E&B. 2019 Information Resource GET IT
Times cited: 25
Polymorphisms in IGF2/H19 gene locus are associated with platinum-based chemotherapeutic response in Chinese patients with epithelial ovarian cancer. Pharmacogenomics. 2019 Academic Article GET IT
Times cited: 6
Interleukin-6 Contributes to the Development of Anemia in Juvenile CKD. Kidney international reports. 2018 Academic Article GET IT
Times cited: 38
Blood pressure and mortality in a prospective cohort of HIV-infected adults in Port-au-Prince, Haiti. Journal of hypertension. 2018 Academic Article GET IT
Times cited: 17
Emerging role of long non-coding RNAs in cisplatin resistance. OncoTargets and therapy. 2018 Information Resource GET IT
Times cited: 67
Pirfenidone inhibits cryoablation induced local macrophage infiltration along with its associated TGFb1 expression and serum cytokine level in a mouse model. Cryobiology. 2018 Academic Article GET IT
Times cited: 12
Elevated phospholipase D activity in androgen-insensitive prostate cancer cells promotes both survival and metastatic phenotypes. Cancer letters. 2018 Academic Article GET IT
Times cited: 13
Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR-Cas9 and ssODN in human cancer cells. Cell & bioscience. 2018 Academic Article GET IT
Times cited: 68
Dual action of NSC606985 on cell growth and apoptosis mediated through PKCδ in prostatic cancer cells. International journal of oncology. 2017 Academic Article GET IT
Times cited: 4
LncRNA H19 is a major mediator of doxorubicin chemoresistance in breast cancer cells through a cullin4A-MDR1 pathway. Oncotarget. 2017 Academic Article GET IT
Times cited: 80
AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling. Oncotarget. 2017 Academic Article GET IT
Times cited: 75
Long Non-Coding RNA as Potential Biomarker for Prostate Cancer: Is It Making a Difference?. International journal of environmental research and public health. 2017 Information Resource GET IT
Times cited: 40
The role of long non-coding RNAs in nasopharyngeal carcinoma: As systemic review. Oncotarget. 2017 Information Resource GET IT
Times cited: 36
DNA Methylation Status of PAX1 and ZNF582 in Esophageal Squamous Cell Carcinoma. International journal of environmental research and public health. 2017 Academic Article GET IT
Times cited: 33
Analysis of ABCG2 methylation in stool samples of Chinese healthy males by pyrosequencing. Die Pharmazie. 2016 Academic Article GET IT
Lack of hepcidin ameliorates anemia and improves growth in an adenine-induced mouse model of chronic kidney disease. American journal of physiology. Renal physiology. 2016 Academic Article GET IT
Times cited: 44
Dissociation of NSC606985 induces atypical ER-stress and cell death in prostate cancer cells. International journal of oncology. 2016 Academic Article GET IT
Times cited: 3
The impact of disease activity and tumour necrosis factor-α inhibitor therapy on cytokine levels in juvenile idiopathic arthritis. Clinical and experimental immunology. 2016 Academic Article GET IT
Times cited: 42
Androgen actions on endothelium functions and cardiovascular diseases. Journal of geriatric cardiology : JGC. 2016 Information Resource GET IT
Times cited: 42
Effect of Recombinant Human Growth Hormone and Rosiglitazone for HIV-Associated Abdominal Fat Accumulation on Adiponectin and other Markers of Inflammation. HIV clinical trials. 2016 Academic Article GET IT
Times cited: 5
Marked Alteration of Rosuvastatin Pharmacokinetics in Healthy Chinese with ABCG2 34G>A and 421C>A Homozygote or Compound Heterozygote. The Journal of pharmacology and experimental therapeutics. 2015 Academic Article GET IT
Times cited: 29
H19 lncRNA mediates 17β-estradiol-induced cell proliferation in MCF-7 breast cancer cells. Oncology reports. 2015 Academic Article GET IT
Times cited: 91
The effect of 5α-reductase-2 deficiency on human fertility. Fertility and sterility. 2014 Information Resource GET IT
Times cited: 71
The kinesin KIF16B mediates apical transcytosis of transferrin receptor in AP-1B-deficient epithelia. The EMBO journal. 2013 Academic Article GET IT
Times cited: 47
Two novel functional single nucleotide polymorphisms of ADRB3 are associated with type 2 diabetes in the Chinese population. The Journal of clinical endocrinology and metabolism. 2013 Academic Article GET IT
Times cited: 12
Suppression of DHT-induced paracrine stimulation of endothelial cell growth by estrogens via prostate cancer cells. The Prostate. 2013 Academic Article GET IT
Times cited: 15
Differential effects of estrogen receptor ligands on regulation of dihydrotestosterone-induced cell proliferation in endothelial and prostate cancer cells. International journal of oncology. 2012 Academic Article GET IT
Times cited: 12
Functional characterisation of a natural androgen receptor missense mutation (N771H) causing human androgen insensitivity syndrome. Andrologia. 2011 Academic Article GET IT
Times cited: 2
17α-Estradiol and genistein inhibit high fat diet induced prostate gene expression and prostate growth in the rat. The Journal of urology. 2011 Academic Article GET IT
Times cited: 5
Androgen stimulates endothelial cell proliferation via an androgen receptor/VEGF/cyclin A-mediated mechanism. American journal of physiology. Heart and circulatory physiology. 2011 Academic Article GET IT
Times cited: 74
Inhibition of aberrant androgen receptor induction of prostate specific antigen gene expression, cell proliferation and tumor growth by 17α-estradiol in prostate cancer. The Journal of urology. 2011 Academic Article GET IT
Times cited: 11
NSC606985 induces apoptosis, exerts synergistic effects with cisplatin, and inhibits hypoxia-stabilized HIF-1alpha protein in human ovarian cancer cells. Cancer letters. 2009 Academic Article GET IT
Times cited: 16
NSC606985, a novel camptothecin analog, induces apoptosis and growth arrest in prostate tumor cells. Cancer chemotherapy and pharmacology. 2008 Academic Article GET IT
Times cited: 19
17alpha-estradiol inhibits LAPC-4 prostatic tumor cell proliferation in cell cultures and tumor growth in xenograft animals. The Prostate. 2007 Academic Article GET IT
Times cited: 12
Sex specificity of ventral anterior cingulate cortex suppression during a cognitive task. Human brain mapping. 2007 Academic Article GET IT
Times cited: 20
Pancreaticoduodenal arterial rupture and hemoabdomen in ACI/SegHsd rats with polyarteritis nodosa. Comparative medicine. 2007 Academic Article GET IT
Times cited: 7
Subcellular proteome analysis of camptothecin analogue NSC606985-treated acute myeloid leukemic cells. Journal of proteome research. 2007 Academic Article GET IT
Times cited: 33
Inhibition of tumor growth and tumor metastasis by a Chinese herbal formula--ZYD88, in an animal model with metastatic Lewis lung carcinoma. Oncology reports. 2007 Academic Article GET IT
Times cited: 2
Therapeutic efficacy of NSC606985, a novel camptothecin analog, in a mouse model of acute promyelocytic leukemia. Leukemia research. 2007 Academic Article GET IT
Times cited: 17
In vivo antitumor activity of ZYD88, a Chinese herbal medicine, in animal models with S180 sarcoma and Ehrlich tumor. Journal of the Society for Integrative Oncology. 2007 Academic Article GET IT
Times cited: 1
Bone mineral density in the complete androgen insensitivity and 5alpha-reductase-2 deficiency syndromes. The Journal of clinical endocrinology and metabolism. 2006 Academic Article GET IT
Times cited: 78
Sex differences in mental rotation: top-down versus bottom-up processing. NeuroImage. 2006 Academic Article GET IT
Times cited: 96
Regulation of prostate 5alpha-reductase-2 gene expression and prostate weight by dietary fat and caloric intake in the rat. The Prostate. 2006 Academic Article GET IT
Times cited: 15
Effects of male sex hormones on gender identity, sexual behavior, and cognitive function. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 2006 Information Resource GET IT
Times cited: 1
Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells. Haematologica. 2005 Academic Article GET IT
Times cited: 20
Receptor isoform and ligand-specific modulation of dihydrotestosterone-induced prostate specific antigen gene expression and prostate tumor cell growth by estrogens. Journal of andrology. 2005 Academic Article GET IT
Times cited: 25
Molecular Basis of Steroid Action in the Prostate. Cellscience. 2005 Academic Article GET IT
Nanomolar concentration of NSC606985, a camptothecin analog, induces leukemic-cell apoptosis through protein kinase Cdelta-dependent mechanisms. Blood. 2005 Academic Article GET IT
Times cited: 49
5α-Reductase Isozymes in the Prostate. Journal of medical sciences (Taipei, Taiwan). 2005 Academic Article GET IT
Fetal hormones and sexual differentiation. Obstetrics and gynecology clinics of North America. 2004 Information Resource GET IT
Times cited: 24
Long-term growth hormone therapy in adulthood results in significant linear growth in siblings with a PROP-1 gene mutation. The Journal of clinical endocrinology and metabolism. 2004 Academic Article GET IT
Times cited: 4
Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1alpha. Leukemia. 2003 Academic Article GET IT
Times cited: 101
Androgen-induced prostate-specific antigen gene expression is mediated via dihydrotestosterone in LNCaP cells. Journal of andrology. 2003 Academic Article GET IT
Times cited: 43
The Chinese medicinal herbal formula ZYD88 inhibits cell growth and promotes cell apoptosis in prostatic tumor cells. Oncology reports. 2003 Academic Article GET IT
Times cited: 7
Differential interaction of estrogen receptor and thyroid hormone receptor isoforms on the rat oxytocin receptor promoter leads to differences in transcriptional regulation. Neuroendocrinology. 2001 Academic Article GET IT
Times cited: 52
Crosstalk between oestrogen receptors and thyroid hormone receptor isoforms results in differential regulation of the preproenkephalin gene. Journal of neuroendocrinology. 2001 Academic Article GET IT
Times cited: 38
Molecular analysis of estrogen induction of preproenkephalin gene expression and its modulation by thyroid hormones. Brain research. Molecular brain research. 2001 Academic Article GET IT
Times cited: 27
Thyroid hormone coadministration inhibits the estrogen-stimulated elevation of preproenkephalin mRNA in female rat hypothalamic neurons. Neuroendocrinology. 1999 Academic Article GET IT
Times cited: 25
A novel mutation in the CAG triplet region of exon 1 of androgen receptor gene causes complete androgen insensitivity syndrome in a large kindred. The Journal of clinical endocrinology and metabolism. 1999 Academic Article GET IT
Times cited: 29
Thyroid hormones and estrogen affect oxytocin gene expression in hypothalamic neurons. Journal of neuroendocrinology. 1999 Academic Article GET IT
Times cited: 62
Differential regulation of AP-1 DNA binding activity in rat hypothalamus and pituitary by estrogen. Brain research. Molecular brain research. 1998 Academic Article GET IT
Times cited: 18
The identification of 5 alpha-reductase-2 and 17 beta-hydroxysteroid dehydrogenase-3 gene defects in male pseudohermaphrodites from a Turkish kindred. The Journal of clinical endocrinology and metabolism. 1998 Academic Article GET IT
Times cited: 67
Gender-specific induction of pituitary RNA by estrogen and its modification by thyroid hormone. Journal of neuroendocrinology. 1997 Academic Article GET IT
Times cited: 12
Interactions between hormonal and environmental signals on hypothalamic neurons molecular mechanisms signaling environmental events. Trends in endocrinology and metabolism: TEM. 1997 Academic Article GET IT
Estrogen and thyroid hormone interaction on regulation of gene expression. Proceedings of the National Academy of Sciences of the United States of America. 1996 Academic Article GET IT
Times cited: 136
Thyroid hormone and estrogen interact to regulate behavior. Proceedings of the National Academy of Sciences of the United States of America. 1996 Academic Article GET IT
Times cited: 95
Hypothalamic cellular and molecular mechanisms helping to satisfy axiomatic requirements for reproduction. Journal of neuroendocrinology. 1996 Review GET IT
Times cited: 24
Meeting the constraints upon behavioral expression through neural and genomic interactive mechanisms. Progress in brain research. 1996 Review GET IT
Times cited: 1
DNA binding of hypothalamic nuclear proteins on estrogen response element and preproenkephalin promoter: modification by estrogen. Neuroendocrinology. 1995 Academic Article GET IT
Times cited: 40
Differential regulation of c-fos, proenkephalin and tyrosine hydroxylase gene expression by metrazole in the hamster adrenal and hippocampus. Neuroscience letters. 1995 Academic Article GET IT
Potential interactions between estrogen receptor and thyroid receptors relevant for neuroendocrine systems. The Journal of steroid biochemistry and molecular biology. 1995 Academic Article GET IT
Times cited: 25
Cloning and characterization of hamster proenkephalin gene. DNA and cell biology. 1994 Academic Article GET IT
Times cited: 16
Localization of a liver-specific enhancer in the apolipoprotein E/C-I/C-II gene locus. Journal of lipid research. 1993 Academic Article GET IT
Times cited: 52
Metrazole induction of c-fos and proenkephalin gene expression in the rat adrenal and hippocampus: pharmacological characterization. Brain research. Molecular brain research. 1993 Academic Article GET IT
Times cited: 15
Metrazole induces the sequential activation of c-fos, proenkephalin, and tyrosine hydroxylase gene expression in the rat adrenal gland: modulation by glucocorticoid and adrenocorticotropic hormone. Molecular pharmacology. 1993 Academic Article GET IT
Times cited: 18
Quantitation of NMDA receptor (NMDAR1) mRNA levels in the adult and developing rat CNS. Brain research. Molecular brain research. 1993 Academic Article GET IT
Times cited: 47
Induction of tyrosine hydroxylase mRNA by protein synthesis inhibitors in the rat adrenal. Molecular and cellular neurosciences. 1993 Academic Article GET IT
Times cited: 5
Quantitation of the levels of tyrosine hydroxylase and preproenkephalin mRNAs in nigrostriatal sites after 6-hydroxydopamine lesions. Life sciences. 1993 Academic Article GET IT
Times cited: 11
Time course of enkephalin mRNA and peptides in cultured rat adrenal medulla. Brain research. Molecular brain research. 1992 Academic Article GET IT
Times cited: 51
Transsynaptic activity regulates proenkephalin and tyrosine hydroxylase gene expression and the response to reserpine in the hamster adrenal. Molecular pharmacology. 1991 Academic Article GET IT
Times cited: 15
Preproenkephalin mRNA and enkephalin in normal and denervated adrenals in the Syrian hamster: comparison with central nervous system tissues. Brain research. Molecular brain research. 1991 Academic Article GET IT
Times cited: 32
Central opioid modulation of fetal cardiovascular function: role of mu- and delta-receptors. The American journal of physiology. 1990 Academic Article GET IT
Times cited: 16
Morphine-induced tachycardia in fetal lambs: a bell-shaped dose-response curve. The Journal of pharmacology and experimental therapeutics. 1989 Academic Article GET IT
Times cited: 21
Dual action of morphine on fetal breathing movements. The Journal of pharmacology and experimental therapeutics. 1988 Academic Article GET IT
Times cited: 19
Prenatal morphine exposure and sleep-wake disturbances in the fetus. Sleep. 1988 Academic Article GET IT
Times cited: 16
Cyclic variation in fetal heart rate and sympathetic activity. American journal of obstetrics and gynecology. 1987 Academic Article GET IT
Times cited: 18

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Research

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Co-investigator Network

Funding awarded

Clinical and Translational Science Center - KL2 awarded by National Center for Advancing Translational Sciences Principal Investigator 2022 - 2027
Clinical and Translational Science Center- Institutional Funding KL2 awarded by CTSC Cost Share Principal Investigator 2022 - 2027

Clinical and Translational Science Center - UL1 awarded by National Center for Advancing Translational Sciences Key Personnel 2022 - 2027
Clinical and Translational Science Center- Institutional CTSC Internal Funding UL1 awarded by CTSC Cost Share Key Personnel 2022 - 2027

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Background

education and training

Ph.D., Weill Cornell Graduate School of Medical Sciences 1992
B.M., Xiangya School of Medicine, Central South University (China) 1982

Contact

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Yuan-Shan Zhu

VIVO Weill Cornell Medical College

Yuan-Shan Zhu Professor of Research in Medicine

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name