Endocrinology

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Inactivation of Cops5 in Smooth Muscle Cells Causes Abnormal Reproductive Hormone Homeostasis and Development in Mice.. 164. 2023
TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways.. 162. 2021
Raloxifene is a Female-specific Proteostasis Therapeutic in the Spinal Cord.. 162. 2021
SMRT Regulates Metabolic Homeostasis and Adipose Tissue Macrophage Phenotypes in Tandem.. 161. 2020
Hepatic Estrogen Sulfotransferase Distantly Sensitizes Mice to Hemorrhagic Shock-Induced Acute Lung Injury 2019
Three-Dimensional Analysis of the Human Pancreas.. 159. 2018
Regeneration of Functional Adrenal Tissue Following Bilateral Adrenalectomy.. 159. 2018
Anti-TCRβ mAb in Combination With Neurogenin3 Gene Therapy Reverses Established Overt Type 1 Diabetes in Female NOD Mice.. 158. 2017
Effects of Endogenous Oxytocin Receptor Signaling in Nucleus Tractus Solitarius on Satiation-Mediated Feeding and Thermogenic Control in Male Rats.. 158. 2017
Attenuated Effects of Bile Acids on Glucose Metabolism and Insulin Sensitivity in a Male Mouse Model of Prenatal Undernutrition.. 158. 2017
Liganded Thyroid Hormone Receptors Transactivate the DNA Methyltransferase 3a Gene in Mouse Neuronal Cells.. 157. 2016
Age-Related Hearing Loss and Degeneration of Cochlear Hair Cells in Mice Lacking Thyroid Hormone Receptor β1.. 156. 2015
Osteocalcin Effect on Human β-Cells Mass and Function.. 156. 2015
Reprogramming Mouse Cells With a Pancreatic Duct Phenotype to Insulin-Producing β-Like Cells.. 156. 2015
The ovary is an alternative site of origin for high-grade serous ovarian cancer in mice.. 156. 2015
Osteocalcin protects against nonalcoholic steatohepatitis in a mouse model of metabolic syndrome.. 155. 2014
Medial prefrontal cortical estradiol rapidly alters memory system bias in female rats: ultrastructural analysis reveals membrane-associated estrogen receptors as potential mediators.. 155. 2014
Characterization of neural estrogen signaling and neurotrophic changes in the accelerated ovarian failure mouse model of menopause.. 155. 2014
Conditional overexpression of liver receptor homolog-1 in female mouse mammary epithelium results in altered mammary morphogenesis via the induction of TGF-β.. 155. 2014
Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivo.. 155. 2014
High-fat feeding-induced hyperinsulinemia increases cardiac glucose uptake and mitochondrial function despite peripheral insulin resistance.. 154. 2013
TNF-α up-regulates protein level and cell surface expression of the leptin receptor by stimulating its export via a PKC-dependent mechanism.. 153. 2012
Estrogen receptors are found in glia and at extranuclear neuronal sites in the dorsal striatum of female rats: evidence for cholinergic but not dopaminergic colocalization.. 153. 2012
The thyroid axis is regulated by NCoR1 via its actions in the pituitary.. 153. 2012
GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation.. 153. 2012
The neural regulation of the hypothalamic-pituitary-thyroid axis. 153:4128-4135. 2012
Role of medium- and short-chain L-3-hydroxyacyl-CoA dehydrogenase in the regulation of body weight and thermogenesis.. 152. 2011
NF-kappaB-inducing kinase (NIK) mediates skeletal muscle insulin resistance: blockade by adiponectin.. 152. 2011
Absence of the glucagon-like peptide-1 receptor does not affect the metabolic phenotype of mice with liver-specific G(s)α deficiency.. 152. 2011
Maternal ghrelin deficiency compromises reproduction in female progeny through altered uterine developmental programming.. 152. 2011
Estradiol alters Fos-immunoreactivity in the hippocampus and dorsal striatum during place and response learning in middle-aged but not young adult female rats.. 152. 2011
The thyrotropin-releasing hormone gene is regulated by thyroid hormone at the level of transcription in vivo.. 151. 2009
A unique human chorionic gonadotropin antagonist suppresses ovarian hyperstimulation syndrome in rats.. 150. 2009
Cathepsin L colocalizes with chromogranin a in chromaffin vesicles to generate active peptides.. 150. 2009
A novel androgen receptor amino terminal region reveals two classes of amino/carboxyl interaction-deficient variants with divergent capacity to activate responsive sites in chromatin.. 150. 2009
Negative regulation of parathyroid hormone (PTH)-activated phospholipase C by PTH/PTH-related peptide receptor phosphorylation and protein kinase A.. 149. 2008
Bioinformatics analysis of targeted metabolomics--uncovering old and new tales of diabetic mice under medication.. 149. 2008
Nuclear and extranuclear estrogen binding sites in the rat forebrain and autonomic medullary areas.. 149. 2008
Expression, structure, function, and evolution of gonadotropin-releasing hormone (GnRH) receptors GnRH-R1SHS and GnRH-R2PEY in the teleost, Astatotilapia burtoni.. 148. 2007
Attenuation of apoptosis by chromogranin A-induced Akt and survivin pathways in prostate cancer cells.. 148. 2007
Impact of impaired receptor internalization on calcium homeostasis in knock-in mice expressing a phosphorylation-deficient parathyroid hormone (PTH)/PTH-related peptide receptor.. 147. 2006
C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts.. 147. 2006
Human chorionic gonadotropin-dependent up-regulation of genes responsible for estrogen sulfoconjugation and export in granulosa cells of luteinizing preovulatory follicles.. 147. 2006
Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activation.. 147. 2006
Stress history and pubertal development interact to shape hypothalamic-pituitary-adrenal axis plasticity.. 147. 2006
BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis.. 147. 2005
Endocrine effects of relaxin overexpression in mice.. 147. 2005
Obesity-related glomerulopathy: insights from gene expression profiles of the glomeruli derived from renal biopsy samples.. 147. 2005
Regulation of glucagon secretion at low glucose concentrations: evidence for adenosine triphosphate-sensitive potassium channel involvement.. 146. 2005
Expression and regulation of glucocorticoid receptor in human placental villous fibroblasts.. 146. 2005
The endogenous growth hormone secretagogue (ghrelin) is synthesized and secreted by chondrocytes.. 146. 2004
Genetic targeting of relaxin and insulin-like factor 3 receptors in mice.. 145. 2004
Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide.. 145. 2004
The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain.. 145. 2004
De novo testosterone production in luteinizing hormone receptor knockout mice after transplantation of leydig stem cells.. 145. 2004
Tumor necrosis factor alpha inhibits insulin-like growth factor I-induced hematopoietic cell survival and proliferation.. 145. 2004
Identification and characterization of a glucagon receptor from the goldfish Carassius auratus: implications for the evolution of the ligand specificity of glucagon receptors in vertebrates.. 145. 2004
The metabolic and cardiovascular effects of hyperthyroidism are largely independent of beta-adrenergic stimulation.. 145. 2004
Leptin signaling targets the thyrotropin-releasing hormone gene promoter in vivo.. 145. 2004
Human chorionic gonadotropin-dependent regulation of 17beta-hydroxysteroid dehydrogenase type 4 in preovulatory follicles and its potential role in follicular luteinization.. 145. 2004
Estradiol increases pre- and post-synaptic proteins in the CA1 region of the hippocampus in female rhesus macaques (Macaca mulatta).. 144. 2003
Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts.. 144. 2003
Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.. 144. 2003
Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin.. 144. 2003
Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene diepoxide exposure of female mice in vivo.. 144. 2003
Induction of hyaluronan synthase 2 by human chorionic gonadotropin in mural granulosa cells of equine preovulatory follicles.. 143. 2002
Orexin A interactions in the hypothalamo-pituitary gonadal axis.. 142. 2001
IGF-binding protein-4 expression and IGF-binding protein-4 protease activity are regulated coordinately in smooth muscle during postnatal development and after vascular injury.. 142. 2001
Targeted overexpression of IGF-I in smooth muscle cells of transgenic mice enhances neointimal formation through increased proliferation and cell migration after intraarterial injury.. 142. 2001
Follicle-stimulating hormone and leukemia inhibitory factor regulate Sertoli cell retinol metabolism.. 142. 2001
Smooth muscle-targeted overexpression of insulin-like growth factor I results in enhanced vascular contractility.. 142. 2001
Characterization of three corticotropin-releasing factor receptors in catfish: a novel third receptor is predominantly expressed in pituitary and urophysis.. 142. 2001
The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion.. 141. 2000
Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation.. 141. 2000
Mechanisms of fibroblast growth factor-2 modulation of vascular endothelial growth factor expression by osteoblastic cells.. 141. 2000
Androgen-induced growth inhibition of androgen receptor expressing androgen-independent prostate cancer cells is mediated by increased levels of neutral endopeptidase.. 141. 2000
Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats.. 141. 2000
Amphiregulin is coordinately expressed with heparin-binding epidermal growth factor-like growth factor in the interstitial smooth muscle of the human prostate.. 140. 1999
Reduced blood pressure and increased sensitivity of the vasculature to parathyroid hormone-related protein (PTHrP) in transgenic mice overexpressing the PTH/PTHrP receptor in vascular smooth muscle.. 140. 1999
Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility.. 140. 1999
Epitope tag mapping of the extracellular and cytoplasmic domains of the rat parathyroid hormone (PTH)/PTH-related peptide receptor.. 139. 1998
Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia.. 139. 1998
Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes.. 138. 1997
Lack of effect of thyroid hormone on late fetal rat brain development.. 138. 1997
Tissue-specific transcription start sites and alternative splicing of the parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor gene: a new PTH/PTHrP receptor splice variant that lacks the signal peptide.. 138. 1997
Cell-specific signal transduction of parathyroid hormone (PTH)-related protein through stably expressed recombinant PTH/PTHrP receptors in vascular smooth muscle cells.. 137. 1996
Molecular cloning of a type A chicken corticotropin-releasing factor receptor with high affinity for urotensin I.. 137. 1996
Cytokine-stimulated expression of inducible nitric oxide synthase by mouse, rat, and human osteoblast-like cells and its functional role in osteoblast metabolic activity.. 136. 1995
Parathyroid hormone (PTH)/PTH-related peptide receptor density modulates activation of phospholipase C and phosphate transport by PTH in LLC-PK1 cells.. 136. 1995
Down-regulation of the receptor for parathyroid hormone (PTH) and PTH-related peptide by transforming growth factor-beta in primary fetal rat osteoblasts.. 136. 1995
Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines.. 136. 1995
Signaling properties of mouse and human corticotropin-releasing factor (CRF) receptors: decreased coupling efficiency of human type II CRF receptor.. 136. 1995
Involvement of cell cycle and mitogen-activated pathways in induction of parathyroid hormone-related protein gene expression in rat aortic smooth muscle cells.. 136. 1995
Down-regulation of parathyroid (PTH)/PTH-related peptide receptor immunoreactivity and PTH binding in opossum kidney cells by PTH and dexamethasone.. 135. 1994
Role of the extracellular regions of the parathyroid hormone (PTH)/PTH-related peptide receptor in hormone binding.. 135. 1994
Determinants of [Arg2]PTH-(1-34) binding and signaling in the transmembrane region of the parathyroid hormone receptor.. 135. 1994
Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor and its messenger ribonucleic acid in rat aortic vascular smooth muscle cells and UMR osteoblast-like cells: cell-specific regulation by angiotensin-II and PTHrP.. 135. 1994
Interleukin-1 regulates corticosterone secretion from the rat adrenal gland through a catecholamine-dependent and prostaglandin E2-independent mechanism.. 135. 1994
Differential regulation of astrocyte plasminogen activators by insulin-like growth factor-I and epidermal growth factor.. 134. 1994
Mechanical stimuli induce vascular parathyroid hormone-related protein gene expression in vivo and in vitro.. 134. 1994
Role of protein kinase-A in homologous down-regulation of parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid in human osteoblast-like SaOS-2 cells.. 134. 1994
Mesenchymal-epithelial interactions and transforming growth factor-beta expression during mouse prostate morphogenesis.. 134. 1994
The extracellular amino-terminal region of the parathyroid hormone (PTH)/PTH-related peptide receptor determines the binding affinity for carboxyl-terminal fragments of PTH-(1-34).. 134. 1994
Regulation of parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acid by glucocorticoids and PTH in ROS 17/2.8 and OK cells.. 134. 1994
Effects of N-terminal, midregion, and C-terminal parathyroid hormone-related peptides on adenosine 3',5'-monophosphate and cytoplasmic free calcium in rat aortic smooth muscle cells and UMR-106 osteoblast-like cells.. 133. 1993
Dynamic regulation of gonadotropin-releasing hormone receptor mRNA levels in the anterior pituitary gland during the rat estrous cycle.. 133. 1993
Parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues.. 133. 1993
Estrogen increases HIP-70/PLC-alpha messenger ribonucleic acid in the rat uterus and hypothalamus.. 133. 1993
Cloned, stably expressed parathyroid hormone (PTH)/PTH-related peptide receptors activate multiple messenger signals and biological responses in LLC-PK1 kidney cells.. 132. 1993
Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor.. 132. 1993
Characterization of the affinities of insulin-like growth factor (IGF)-binding proteins 1-4 for IGF-I, IGF-II, IGF-I/insulin hybrid, and IGF-I analogs.. 132. 1993
Interleukin-1 activates protein kinase A and stimulates adrenocorticotropic hormone release from AtT-20 cells.. 132. 1993
Parathyroid hormone (PTH) stimulates adrenocorticotropin release in AtT-20 cells stably expressing a common receptor for PTH and PTH-related peptide.. 132. 1993
FOS expression in gonadotropin-releasing hormone neurons: enhancement by steroid treatment and mating.. 131. 1992
Involvement of protein kinase-C in the mitogenic effect of insulin-like growth factor-I on rat astrocytes.. 131. 1992
Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies.. 131. 1992
Prostaglandin E1 inhibits collagenase gene expression in rabbit synoviocytes and human fibroblasts.. 131. 1992
Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent and cAMP-independent regulation of parathyroid hormone receptors on UMR 106-01 osteoblastic osteosarcoma cells.. 129. 1991
Effects of flutamide and finasteride on rat testicular descent.. 129. 1991
Alpha 2-macroglobulin is not an acute-phase protein in the rat testis.. 128. 1991
Gonadotropin-releasing hormone (GnRH) agonists and GnRH antagonists do not alter endogenous GnRH secretion in short-term castrated rams.. 127. 1990
Generation of regulatory oxysterols: 26-hydroxylation of cholesterol by ovarian mitochondria.. 127. 1990
The effects of estradiol on the growth patterns of estrogen receptor-positive hypothalamic cell lines.. 126. 1990
Inactivation of pertussis toxin-sensitive guanyl nucleotide-binding proteins increase parathyroid hormone receptors and reverse agonist-induced receptor down-regulation in ROS 17/2.8 cells.. 125. 1989
Pituitary insulin-like growth factor-I gene expression: regulation by triiodothyronine and growth hormone.. 125. 1989
Non-homologous sequences of parathyroid hormone and the parathyroid hormone related peptide bind to a common receptor on ROS 17/2.8 cells.. 125. 1989
Parathyroid hormone causes translocation of protein kinase-C from cytosol to membranes in rat osteosarcoma cells.. 124. 1989
Functional and structural differences in human and rat-derived insulin receptors: characterization of the beta-subunit kinase activity.. 123. 1988
Hepatic vasopressin receptor: differential effects of divalent cations, guanine nucleotides, and N-ethylmaleimide on agonist and antagonist interactions with the V1 subtype receptor.. 123. 1988
Monoclonal antibodies against the androgen receptor: recognition of human and other mammalian androgen receptors.. 123. 1988
Regulation of pituitary insulin-like growth factor-I messenger ribonucleic acid levels in rats harboring somatomammotropic tumors: implications for growth hormone autoregulation.. 122. 1988
delta 9-[16 alpha-125I]iodo-19-nortestosterone: a gamma-emitting photoaffinity label for the progesterone receptor.. 122. 1988
Atrial natriuretic peptide inhibits the stimulation of aldosterone secretion but not the transient increase in intracellular free calcium concentration induced by angiotensin II addition.. 122. 1988
Growth hormone-releasing factor immunoreactivity in the hypothalamus and cortex of the rat: in vivo and in vitro studies.. 122. 1988
Sertoli cell-only syndrome produced by cold testicular ischemia.. 122. 1988
Presence of immunoreactive corticotropin-releasing factor in rat testis.. 122. 1988
Calcium-dependent control of corticotropin release in rat anterior pituitary cell cultures.. 121. 1987
Insulin-like growth factor I gene expression in GH3 rat pituitary cells: messenger ribonucleic acid content, immunocytochemistry, and secretion.. 120. 1987
Relative increase in insulin-like growth factor I messenger ribonucleic acid levels in compensatory renal hypertrophy.. 120. 1987
Synthetic atrial natriuretic factors (ANFs) stimulate guanine 3',5'-monophosphate production but not hormone release in rat pituitary cells: peptide contamination with a gonadotropin-releasing hormone agonist explains luteinizing hormone-releasing activity of certain ANFs.. 120. 1987
Thyrotropin-releasing hormone stimulation of prolactin secretion is coordinately but not synergistically regulated by an elevation of cytoplasmic calcium and 1,2-diacylglycerol.. 119. 1986
Role of arachidonic acid in the regulation of adrenocorticotropin release from rat anterior pituitary cell cultures.. 119. 1986
Biphasic inhibition of adrenocorticotropin release by corticosterone in cultured anterior pituitary cells.. 119. 1986
Characterization of a specific, high affinity [3H]arginine8 vasopressin-binding site on liver microsomes from different strains of rat and the role of magnesium.. 118. 1986
Somatostatin receptors are biologically active before they are inserted into the plasma membrane.. 118. 1986
Involvement of protein kinase C in the regulation of adrenocorticotropin release from rat anterior pituitary cells.. 118. 1986
Nipple differentiation in fetal male rats treated with an inhibitor of the enzyme 5 alpha-reductase: definition of a selective role for dihydrotestosterone.. 118. 1986
The effects of growth hormone, prolactin, corticotropin, and thyrotropin on the production and secretion of somatostatin by hypothalamic cells in vitro.. 117. 1985
Insulin receptors on cultured hypothalamic cells: functional and structural differences from receptors on peripheral target cells.. 116. 1985
The development of a male pseudohermaphroditic rat using an inhibitor of the enzyme 5 alpha-reductase.. 116. 1985
Demonstration of an antiglucocorticoid action of progesterone on the corticosterone inhibition of beta-endorphin release by rat anterior pituitary in primary culture.. 115. 1984
Heterogeneous deoxyribonucleic acid-binding forms of rabbit uterine progesterone receptor.. 114. 1984
Thyrotropin (TSH)-releasing hormone decreases phosphatidylinositol and increases unesterified arachidonic acid in thyrotropic cells: possible early events in stimulation of TSH secretion.. 114. 1984
Reciprocal day/night relationship between serotonin oxidation and N-acetylation products in the rat pineal gland.. 113. 1983
Somatostatin biosynthesis by cerebral cortical cells in monolayer culture.. 113. 1983
Insulin binding and degradation in vascular endothelial cells: modulation by cell growth and culture organization.. 113. 1983
Sodium- and calcium-dependent somatostatin release from dissociated cerebral cortical cells in culture.. 110. 1982
Hormone ontogeny in the ovine fetus. IX. Luteinizing hormone and follicle-stimulating hormone response to luteinizing hormone-releasing factor in mid- and late gestation and in the neonate.. 108. 1981
Hormone ontogeny in the ovine fetus. VII. Circulating luteinizing hormone and follicle-stimulating hormone in mid- and late gestation.. 108. 1981
Sertoli cell nuclear transcriptional activity: stimulation by follicle-stimulating hormone and testosterone in vitro.. 108. 1981
Circadian periodicity of epidermal growth factor and its abolition by superior cervical ganglionectomy.. 99. 1976
Adrenal epinephrine and phenylethanolamine N-methyl transferase (PNMT) activity in the rat bearing a transplantable pituitary tumor.. 83. 1968
Early Life Stress Affects the HPT Axis Response in a Sexually Dimorphic Manner.. 162. 2021
Testosterone production in the aging male: where does the slowdown occur?. 145. 2004
Adrenal Steroids and Resistance to Hormonal Blockade of Prostate and Breast Cancer. 2023

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