Neurobiology of aging
Journal
Overview
publication venue for
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Age-related differences in perception and coding of attractive odorants in mice..
137.
2024
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In vivo tau is associated with change in memory and processing speed, but not reasoning, in cognitively unimpaired older adults..
133.
2023
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Machine learning approaches based on fibroblast morphometry do not predict ALS..
130.
2023
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Elevated levels of tripeptidyl peptidase 1 do not ameliorate pathogenesis in a mouse model of Alzheimer disease..
118.
2022
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Vascular endothelial growth factor associated dissimilar cerebrovascular phenotypes in two different mouse models of Alzheimer's Disease..
107.
2021
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Diffusion tensor-based analysis of white matter in the healthy aging canine brain..
105.
2021
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Sex differences in in vivo tau neuropathology in a multiethnic sample of late middle-aged adults..
103.
2021
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Global brain volume and N-acetyl-aspartate decline over seven decades of normal aging..
98.
2020
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Metabolic syndrome and its components in relation to in vivo brain amyloid and neurodegeneration in late middle age..
97.
2020
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Microglial activation, but not tau pathology, is independently associated with amyloid positivity and memory impairment..
85.
2019
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The relationship between white matter hyperintensities and cognitive reference abilities across the life span..
83.
2019
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Neurometabolites and associations with cognitive deficits in mild cognitive impairment: a magnetic resonance spectroscopy study at 7 Tesla..
73.
2018
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Effects of estrogen and aging on synaptic morphology and distribution of phosphorylated Tyr1472 NR2B in the female rat hippocampus..
73.
2018
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Basal forebrain septal nuclei are enlarged in healthy subjects prior to the development of Alzheimer's disease..
65.
2018
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Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models..
44.
2016
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Resveratrol attenuates peripheral and brain inflammation and reduces ischemic brain injury in aged female mice..
44.
2016
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Vagus nerve stimulation during rehabilitative training enhances recovery of forelimb function after ischemic stroke in aged rats..
43.
2016
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Differences between chronological and brain age are related to education and self-reported physical activity..
40.
2016
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The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice..
37.
2015
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Aβ-related hyperactivation in frontoparietal control regions in cognitively normal elderly..
36.
2015
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Breadth and age-dependency of relations between cortical thickness and cognition..
36.
2015
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Stratified gene expression analysis identifies major amyotrophic lateral sclerosis genes..
36.
2015
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Periodontal disease associates with higher brain amyloid load in normal elderly..
36.
2014
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Interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals..
35.
2013
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Blood pressure decrease correlates with tau pathology and memory decline in hypertensive elderly..
35.
2013
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Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents..
34.
2012
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Whole brain N-acetylaspartate concentration is conserved throughout normal aging..
33.
2012
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Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation..
33.
2011
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Blood pressure is associated with higher brain amyloid burden and lower glucose metabolism in healthy late middle-age persons..
33.
2011
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Alzheimer's disease markers, hypertension, and gray matter damage in normal elderly..
33.
2011
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Maternal age affects brain metabolism in adult children of mothers affected by Alzheimer's disease..
33.
2011
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Structural brain changes in normal individuals with a maternal history of Alzheimer's..
32.
2011
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Nonlinear time course of brain volume loss in cognitively normal and impaired elders..
33.
2010
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Accumulation of resident and peripheral dendritic cells in the aging CNS..
33.
2010
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Phosphorylated tau 231, memory decline and medial temporal atrophy in normal elders..
32.
2010
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Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal..
31.
2008
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Co-occurrence of Alzheimer's disease ß-amyloid and τ pathologies at synapses..
31.
2008
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Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model..
30.
2008
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18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease..
30.
2008
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The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease..
30.
2007
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Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment..
30.
2007
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Enhanced and bilateralized visual sensory processing in the ventral stream may be a feature of normal aging..
29.
2007
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A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice..
29.
2007
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Degradation of fibrillar forms of Alzheimer's amyloid beta-peptide by macrophages..
29.
2007
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Hippocampal hypometabolism predicts cognitive decline from normal aging..
29.
2007
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Hippocampal volumes are larger in postmenopausal women using estrogen therapy compared to past users, never users and men: a possible window of opportunity effect..
29.
2006
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Imaging markers of mild cognitive impairment: multivariate analysis of CBF SPECT..
28.
2006
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Subjective memory complaints in aging are associated with elevated cortisol levels..
26.
2005
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Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment..
27.
2005
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Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration..
27.
2005
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Mitochondrial function in fibroblasts with aging in culture and/or Alzheimer's disease..
26.
2005
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Somatic mitochondrial DNA mutations in single neurons and glia..
26.
2004
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Aging, sexual dimorphism, and hemispheric asymmetry of the cerebral cortex: replicability of regional differences in volume..
25.
2004
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Serotonin modulation of cerebral glucose metabolism in normal aging..
25.
2004
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Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease..
25.
2004
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Age-related differences in brain activation during emotional face processing..
24.
2003
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Abeta42 generation is toxic to endothelial cells and inhibits eNOS function through an Akt/GSK-3beta signaling-dependent mechanism..
24.
2003
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Hippocampal formation glucose metabolism and volume losses in MCI and AD..
22.
2001
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Familial Alzheimer's disease presenilin-1 mutants potentiate cell cycle arrest..
21.
2000
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Age-related differences in visual perception: a PET study..
21.
2000
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Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer's disease..
21.
2000
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Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease..
18.
1997
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Abnormalities in Alzheimer's disease fibroblasts bearing the APP670/671 mutation..
18.
1997
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Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease..
18.
1997
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Neurofibrillary pathology--correlation with hippocampal formation atrophy in Alzheimer disease..
17.
1996
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Memory improvement following induced hyperinsulinemia in Alzheimer's disease..
17.
1996
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Neurotoxicity of A beta amyloid protein in vitro is not altered by calcium channel blockade..
16.
1995
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Resting [Ca2+]i and [Ca2+]i transients are similar in fibroblasts from normal and Alzheimer's donors..
13.
1992
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Inositol phosphates and intracellular calcium after bradykinin stimulation in fibroblasts from young, normal aged and Alzheimer donors..
12.
1991
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Will neurotrophic agents be harmful in Alzheimer's disease?.
10.
1989
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Causes of cell damage in hypoxia/ischemia, aging and Alzheimer's disease..
10.
1989
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Altered response of fibroblasts from aged and Alzheimer donors to drugs that elevate cytosolic free calcium..
9.
1988
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Positron emission tomography with the deoxyglucose technique and the diagnosis of Alzheimer's disease..
9.
1988
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Positron emission tomography studies of normal aging: a replication of PET III and 18-FDG using PET VI and 11-CDG..
8.
1987
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Effect of age on behavioral and enzymatic changes during thiamin deficiency..
8.
1987
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Selective alteration of mouse brain neurotransmitter release with age..
8.
1987
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Reduced incidence of left-handedness in clinically diagnosed dementia of the Alzheimer type..
7.
1986
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Human red blood cell choline uptake with age and Alzheimer's disease..
7.
1986
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Subsynaptosomal distribution of calcium during aging and 3,4-diaminopyridine treatment..
6.
1985
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Amelioration of age-related neurochemical and behavioral deficits by 3,4-diaminopyridine..
4.
1983
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Central amine metabolism in Alzheimer's disease: in vivo relationship to cognitive deficit..
2.
1981
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Neurotransmitter and carbohydrate metabolism during aging and mild hypoxia..
2.
1981
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Computed tomography evaluations of brain-behavior relationships in senile dementia of the Alzheimer's type..
1.
1980
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Positron emission tomography in the study of aging and senile dementia..
1.
1980
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Oxidative stress in Alzheimer's disease..
26.
2005
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Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease.
2004
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Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia.
2005
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Calcium and the aging nervous system.
1987
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