Circulation research

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Rewiring Endothelial Sphingolipid Metabolism to Favor S1P Over Ceramide Protects From Coronary Atherosclerosis. 2024
Essential Role of Endothelial Sphingolipid Biosynthesis in Cerebrovascular Homeostasis. 2023
An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis.. 133. 2023
PPARγ and NOTCH Regulate Regional Identity in the Murine Cardiac Outflow Tract. 2022
SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells. 2022
Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome.. 129. 2021
Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury.. 129. 2021
NAD⁺ Repletion Reverses Heart Failure With Preserved Ejection Fraction.. 128. 2021
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.. 129. 2021
Endothelial S1P₁ Signaling Counteracts Infarct Expansion in Ischemic Stroke.. 128. 2020
Adrenergic Ca_V1.2 Activation via Rad Phosphorylation Converges at α_1C I-II Loop.. 128. 2020
Rapamycin-Loaded Biomimetic Nanoparticles Reverse Vascular Inflammation.. 126. 2019
Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 ^V617F Mice.. 123. 2018
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential.. 123. 2018
Down Syndrome Critical Region 1 Gene, Rcan1, Helps Maintain a More Fused Mitochondrial Network.. 122. 2018
PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics.. 121. 2017
Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides.. 121. 2017
Peripheral Blood Cytokine Levels After Acute Myocardial Infarction: IL-1β- and IL-6-Related Impairment of Bone Marrow Function.. 120. 2017
20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (G_q) to Affect Vascular Function and Trigger Hypertension.. 120. 2017
AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling.. 120. 2017
Hypertension-Linked Pathophysiological Alterations in the Gut.. 120. 2016
Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation.. 119. 2016
LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis.. 119. 2016
A Case of Sudden Death in Decameron IV.6: Aortic Dissection or Atrial Myxoma?. 119. 2016
ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.. 119. 2016
Proton Pump Inhibitors Accelerate Endothelial Senescence.. 118. 2016
Involvement of bone marrow cells and neuroinflammation in hypertension.. 117. 2015
Efficient gene disruption in cultured primary human endothelial cells by CRISPR/Cas9.. 117. 2015
Bone marrow characteristics associated with changes in infarct size after STEMI: a biorepository evaluation from the CCTRN TIME trial.. 116. 2014
Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis.. 115. 2014
Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes.. 115. 2014
Fibroblast growth factor homologous factors modulate cardiac calcium channels.. 113. 2013
Pegylation of high-density lipoprotein decreases plasma clearance and enhances antiatherogenic activity.. 113. 2013
The Congenital Heart Disease Genetic Network Study: rationale, design, and early results.. 112. 2013
Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up.. 112. 2012
Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism.. 109. 2011
Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts.. 109. 2011
Intramyocardial, autologous CD34+ cell therapy for refractory angina.. 109. 2011
Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive families.. 108. 2011
Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling.. 108. 2010
Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes.. 107. 2010
Role of cardiac myocyte CXCR4 expression in development and left ventricular remodeling after acute myocardial infarction.. 107. 2010
Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes.. 106. 2010
Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia.. 106. 2009
Dynamical mechanism for subcellular alternans in cardiac myocytes.. 105. 2009
Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis.. 105. 2009
Accessory subunit KChIP2 modulates the cardiac L-type calcium current.. 104. 2009
Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish.. 104. 2009
VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling.. 103. 2008
ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin.. 102. 2008
Hemin upregulates Egr-1 expression in vascular smooth muscle cells via reactive oxygen species ERK-1/2-Elk-1 and NF-kappaB.. 102. 2007
Cyclin A2 induces cardiac regeneration after myocardial infarction and prevents heart failure.. 100. 2007
Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy.. 100. 2007
Nonbone marrow-derived circulating progenitor cells contribute to postnatal neovascularization following tissue ischemia.. 100. 2007
Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance.. 99. 2006
Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium.. 99. 2006
Essential role of Smad3 in angiotensin II-induced vascular fibrosis.. 98. 2006
KCNQ1 assembly and function is blocked by long-QT syndrome mutations that disrupt interaction with calmodulin.. 98. 2006
FcgammaRIIB mediates C-reactive protein inhibition of endothelial NO synthase.. 97. 2005
Thrombopoietin gene transfer-mediated enhancement of angiogenic responses to acute ischemia.. 97. 2005
Prevention of cardiac hypertrophy by atorvastatin in a transgenic rabbit model of human hypertrophic cardiomyopathy.. 97. 2005
Adenovirus vector E4 gene regulates connexin 40 and 43 expression in endothelial cells via PKA and PI3K signal pathways.. 96. 2005
Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals.. 95. 2004
Platelet-derived growth factor-AB promotes the generation of adult bone marrow-derived cardiac myocytes.. 94. 2004
Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen.. 94. 2003
Novel vascular endothelial growth factor binding domains of fibronectin enhance vascular endothelial growth factor biological activity.. 91. 2002
Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells.. 90. 2002
Young adult bone marrow-derived endothelial precursor cells restore aging-impaired cardiac angiogenic function.. 90. 2002
Frequency analysis of ventricular fibrillation in Swine ventricles.. 90. 2002
Recombinant annexin II modulates impaired fibrinolytic activity in vitro and in rat carotid artery.. 89. 2001
eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization.. 89. 2001
Infection of endothelium with E1(-)E4(+), but not E1(-)E4(-), adenovirus gene transfer vectors enhances leukocyte adhesion and migration by modulation of ICAM-1, VCAM-1, CD34, and chemokine expression.. 88. 2001
Novel polymorphisms in promoter region of atp binding cassette transporter gene and plasma lipids, severity, progression, and regression of coronary atherosclerosis and response to therapy.. 88. 2001
Dynamics of intramural and transmural reentry during ventricular fibrillation in isolated swine ventricles.. 88. 2001
Cyclooxygenase-1 participates in selected vasodilator responses of the cerebral circulation.. 88. 2001
Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43.. 88. 2001
Vascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cells.. 88. 2001
cAMP pulse during preservation inhibits the late development of cardiac isograft and allograft vasculopathy.. 86. 2000
A variant of p22(phox), involved in generation of reactive oxygen species in the vessel wall, is associated with progression of coronary atherosclerosis.. 86. 2000
Antisense intercellular adhesion molecule-1 (ICAM-1) oligodeoxyribonucleotide delivered during organ preservation inhibits posttransplant ICAM-1 expression and reduces primary lung isograft failure.. 86. 2000
Reversal of GATA-6 downregulation promotes smooth muscle differentiation and inhibits intimal hyperplasia in balloon-injured rat carotid artery.. 84. 1999
Thrombin stimulates vascular smooth muscle cell polyamine synthesis by inducing cationic amino acid transporter and ornithine decarboxylase gene expression.. 83. 1998
Cardiac graft intercellular adhesion molecule-1 (ICAM-1) and interleukin-1 expression mediate primary isograft failure and induction of ICAM-1 in organs remote from the site of transplantation.. 82. 1998
Exacerbation of cerebral injury in mice that express the P-selectin gene: identification of P-selectin blockade as a new target for the treatment of stroke.. 81. 1997
Skeletal muscle-specific myosin binding protein-H is expressed in Purkinje fibers of the cardiac conduction system.. 80. 1997
Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells.. 80. 1997
cAMP-mediated vascular protection in an orthotopic rat lung transplant model. Insights into the mechanism of action of prostaglandin E1 to improve lung preservation.. 79. 1996
Differential regulation of L-arginine transport and nitric oxide production by vascular smooth muscle and endothelium.. 78. 1996
Regulated expression of the ets-1 transcription factor in vascular smooth muscle cells in vivo and in vitro.. 78. 1996
VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo.. 77. 1995
Enhanced preservation of orthotopically transplanted rat lungs by nitroglycerin but not hydralazine. Requirement for graft vascular homeostasis beyond harvest vasodilation.. 76. 1995
Characterization of thrombin receptor expression during vascular lesion formation.. 75. 1994
Expression and insulin-like growth factor-dependent proteolysis of insulin-like growth factor-binding protein-4 are regulated by cell confluence in vascular smooth muscle cells.. 74. 1994
Efficient gene transfer into myocardium by direct injection of adenovirus vectors.. 73. 1993
Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide.. 73. 1993
Developmentally regulated herpesvirus plaque formation in arterial smooth muscle cells.. 73. 1993
In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors.. 72. 1993
Nitric oxide is a mediator of hypoxic coronary vasodilatation. Relation to adenosine and cyclooxygenase-derived metabolites.. 71. 1992
Platelet-derived growth factor isoforms decrease insulin-like growth factor I gene expression in rat vascular smooth muscle cells and selectively stimulate the biosynthesis of insulin-like growth factor binding protein 4.. 71. 1992
Adenosine-sensitive afterdepolarizations and triggered activity in guinea pig ventricular myocytes.. 70. 1992
NG-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. A role for nitric oxide in the central regulation of sympathetic tone?. 70. 1992
Intrathoracic current flow during transthoracic defibrillation in dogs. Transcardiac current fraction.. 67. 1990
L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits.. 67. 1990
Relation between transcardiac and transthoracic current during defibrillation in humans.. 67. 1990
Induction of insulin-like growth factor I messenger RNA in rat aorta after balloon denudation.. 66. 1990
Calcium channel blockers enhance cholesteryl ester hydrolysis and decrease total cholesterol accumulation in human aortic tissue.. 66. 1990
N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor.. 65. 1989
Developmental changes in the electrophysiological properties and the beta-adrenergic receptor-effector complex in atrial fibers of the canine coronary sinus.. 65. 1989
Alterations in calcium antagonist receptors and sodium-calcium exchange in cardiomyopathic hamster tissues.. 65. 1989
Myogenic vasoregulation overrides local metabolic control in resting rat skeletal muscle.. 60. 1987
Effect of norepinephrine and cyclic AMP on intracellular sodium ion activity and contractile force in canine cardiac Purkinje fibers.. 59. 1986
Release of histamine by sympathetic nerve stimulation in the guinea pig heart and modulation of adrenergic responses. A physiological role for cardiac histamine?. 54. 1984
The effect of warming on adrenergic neurotransmission in canine cutaneous vein.. 54. 1984
Role of intravascular coagulation and granulocytes in lung vascular injury after bone marrow embolism.. 50. 1982
Serial evaluation of the renin-angiotensin-aldosterone system in caval dogs.. 42. 1978
Apolipoprotein B retention in the grossly normal and atherosclerotic human aorta.. 41. 1977
Quantification of apolipoprotein B in grossly normal human aorta.. 40. 1977
Localization patterns of plasma apolipoproteins in human atherosclerotic lesions.. 37. 1975
Stanford Cardiovascular Institute.. 124. 2019
Therapeutic transdifferentiation: a novel approach for vascular disease.. 112. 2013
Regenerating Hearts by Arresting Development With Hypothyroidism. 2019
Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth. 2014
Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure. 2019
Pivoting From PTH to FGF23 to Mend Breaking Hearts on Dialysis.. 128. 2021
A Missing LNC in Vascular Diseases.. 121. 2017
Introduction to the Stroke Compendium.. 120. 2017
Calcineurin finds a new partner in the L-type Ca2+ channel.. 105. 2009
Bioresorbable Scaffold: The Emerging Reality and Future Directions. 2017
Cryptogenic Stroke: Research and Practice. 2017
Brain-Gut-Bone Marrow Axis: Implications for Hypertension and Related Therapeutics. 2016
Endothelial cells derived from nuclear reprogramming. 2012
The role of dietary polyunsaturated fat in lowering blood cholesterol in man. 1978
New Directions in Therapeutic Angiogenesis and Arteriogenesis in Peripheral Arterial Disease. 2021
Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic? 2021
Inflammation and Its Role in Regeneration and Repair. 2019
Promise and Perils of Big Data and Artificial Intelligence in Clinical Medicine and Biomedical Research. 2018
Antiplatelet and anticoagulation therapy for acute coronary syndromes. 2014
Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond. 2003
Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. 2002
Molecular pathogenesis of the antiphospholipid syndrome. 2002

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Circulation research Journal

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