publication venue for
- Author Correction: Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors. 2024
- Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor-immune hubs. 2024
- Simultaneous single-cell analysis of 5mC and 5hmC with SIMPLE-seq. 2024
- Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons. 2024
- Generation of precision preclinical cancer models using regulated in vivo base editing. 2023
- Engineered phage with antibacterial CRISPR-Cas selectively reduce E. coli burden in mice. 2023
- A relay velocity model infers cell-dependent RNA velocity. 2023
- Accurate isoform discovery with IsoQuant using long reads. 2023
- Integration of whole transcriptome spatial profiling with protein markers. 2023
- Nanobody-tethered transposition enables multifactorial chromatin profiling at single-cell resolution. 2022
- High-throughput retrieval of target sequences from complex clone libraries using CRISPRi.. 41. 2022
- Identifying synergistic high-order 3D chromatin conformations from genome-scale nanopore concatemer sequencing. 2022
- Inferring gene expression from cell-free DNA fragmentation profiles.. 40. 2022
- Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue.. 40. 2022
- Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells.. 40. 2022
- Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants. 2022
- Curated variation benchmarks for challenging medically relevant autosomal genes. 2022
- Improved prediction of immune checkpoint blockade efficacy across multiple cancer types. 2021
- Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing.. 39. 2021
- Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study.. 39. 2021
- Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing.. 39. 2021
- Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology.. 39. 2021
- Voices of biotech research.. 39. 2021
- A robust benchmark for detection of germline large deletions and insertions.. 38. 2020
- The therapeutic landscape for cells engineered with chimeric antigen receptors.. 38. 2020
- Highly efficient expression of circular RNA aptamers in cells using autocatalytic transcripts.. 37. 2019
- Best practices for benchmarking germline small-variant calls in human genomes.. 37. 2019
- NFIA is a gliogenic switch enabling rapid derivation of functional human astrocytes from pluripotent stem cells.. 37. 2019
- Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells. 2018
- Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.. 36. 2018
- Optimized base editors enable efficient editing in cells, organoids and mice.. 36. 2018
- Antigen receptor repertoire profiling from RNA-seq data.. 35. 2017
- An atlas of B-cell clonal distribution in the human body.. 35. 2017
- Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer.. 35. 2017
- Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells.. 35. 2017
- A recellularized human colon model identifies cancer driver genes.. 34. 2016
- Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.. 34. 2015
- Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.. 33. 2015
- Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.. 33. 2015
- Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events.. 33. 2015
- Inducible in vivo genome editing with CRISPR-Cas9.. 33. 2015
- Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells.. 32. 2014
- Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells.. 32. 2014
- Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials.. 32. 2014
- A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium.. 32. 2014
- Detecting and correcting systematic variation in large-scale RNA sequencing data.. 32. 2014
- Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study.. 32. 2014
- Normalization of RNA-seq data using factor analysis of control genes or samples.. 32. 2014
- Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer.. 32. 2014
- Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.. 31. 2013
- Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.. 31. 2013
- A single-molecule long-read survey of the human transcriptome.. 31. 2013
- Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy.. 31. 2013
- Single-base resolution methylomes of tomato fruit development reveal epigenome modifications associated with ripening.. 31. 2013
- High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire.. 31. 2013
- Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells.. 31. 2012
- Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression.. 30. 2012
- Three-dimensional reconstruction of protein networks provides insight into human genetic disease.. 30. 2012
- De novo genome sequencing and comparative genomics of date palm (Phoenix dactylifera).. 29. 2011
- Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells.. 29. 2010
- Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi.. 29. 2010
- The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models.. 28. 2010
- Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells.. 28. 2010
- Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling.. 28. 2010
- Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system.. 28. 2010
- Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent.. 28. 2010
- Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells.. 27. 2009
- Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs.. 27. 2009
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.. 27. 2009
- Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.. 27. 2008
- Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.. 26. 2008
- Tumor immunotherapy across MHC barriers using allogeneic T-cell precursors.. 26. 2008
- Human embryonic stem cell derivation from poor-quality embryos.. 26. 2008
- Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo.. 26. 2008
- Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells.. 25. 2007
- Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.. 25. 2007
- Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities.. 24. 2006
- Stem cell-derived erythroid cells mediate long-term systemic protein delivery.. 24. 2006
- Sequencing genomes from single cells by polymerase cloning.. 24. 2006
- A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference.. 24. 2005
- Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors.. 22. 2004
- Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord.. 22. 2004
- Probing the precision of the mitotic clock with a live-cell fluorescent biosensor.. 22. 2004
- Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.. 21. 2003
- Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes.. 21. 2003
- Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing.. 21. 2003
- Fingerprinting the circulating repertoire of antibodies from cancer patients.. 21. 2002
- Protein-dependent ribozymes report molecular interactions in real time.. 20. 2002
- Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta /CD28 receptor.. 20. 2002
- High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain.. 19. 2001
- Universal DNA array detection of small insertions and deletions in BRCA1 and BRCA2.. 18. 2000
- Induction of human cytotoxic T lymphocytes by artificial antigen-presenting cells.. 18. 2000
- Augmentation of blood platelet levels by intratracheal administration of an adenovirus vector encoding human thrombopoietin cDNA.. 15. 1997
- Spatial dynamics of GFP-tagged proteins investigated by local fluorescence enhancement.. 14. 1996
- Small molecule nerve growth factor analogs image receptors in vivo.. 14. 1996
- The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing.. 38. 2020
- Chinese scientists and US leadership in the life sciences.. 37. 2019
- Software tools for single-cell tracking and quantification of cellular and molecular properties.. 34. 2016
- Good laboratory practice for clinical next-generation sequencing informatics pipelines.. 33. 2015
- Transforming lymph nodes into tissue factories.. 30. 2012
- Tracing cancer networks with phosphoproteomics.. 28. 2010
- High-content imaging.. 28. 2010
- Do-it-yourself (DIY) pathology.. 26. 2008
- The terminology of teratocarcinomas and teratomas.. 25. 2007
- An open-source oligomicroarray standard for human and mouse.. 20. 2002
- Sweet surrender to chemical genetics.. 20. 2002
- Happy coupling: recruiting both antigen and effector function.. 15. 1997
- Reigning in regulatory T-cell function. 2015
- A dynamic picture of protein behavior in cells. 2015
- Scalable, accessible and reproducible reference genome assembly and evaluation in Galaxy. 2024
- The GA4GH Phenopacket schema defines a computable representation of clinical data. 2022
- Clarity and claims in variation/mutation databasing. 2011
- The ABCs of artificial antigen presentation. 2004
- Medicare price negotiation and pharmaceutical innovation following the Inflation Reduction Act. 2024