European journal of pharmacology

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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR).. 945. 2023
Effect of metformin on intact mitochondria from liver and brain: Concept revisited.. 931. 2022
A druggable pocket on PSMD10^Gankyrin that can accommodate an interface peptide and doxorubicin.. 915. 2021
Lacosamide diminishes dryness-induced hyperexcitability of corneal cold sensitive nerve terminals.. 787. 2016
K303⁶·⁵⁸ in the μ opioid (MOP) receptor is important in conferring selectivity for covalent binding of β-funaltrexamine (β-FNA).. 748. 2014
Cardioprotection of the enkephalin analog Eribis peptide 94 in a rat model of ischemia and reperfusion is highly dependent on dosing regimen and timing of administration.. 747. 2014
Adenosine prevents isoprenaline-induced cardiac contractile and electrophysiological dysfunction.. 718. 2013
Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells.. 637. 2010
Pitavastatin suppresses mitogen activated protein kinase-mediated Erg-1 induction in human vascular smooth muscle cells.. 606. 2009
Effects of a Western diet versus high glucose on endothelium-dependent relaxation in murine micro- and macro-vasculature.. 601. 2008
Acute and chronic heroin dependence in mice: contribution of opioid and excitatory amino acid receptors.. 586. 2008
A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.. 584. 2008
Therapeutic effect of epigallocatechin-3-gallate in a mouse model of colitis.. 579. 2007
Increased oxidative stress in the streptozotocin-induced diabetic apoE-deficient mouse: changes in expression of NADPH oxidase subunits and eNOS.. 561. 2007
Calcium-activated potassium channel and connexin expression in small mesenteric arteries from eNOS-deficient (eNOS-/-) and eNOS-expressing (eNOS+/+) mice.. 560. 2007
Nitrosothiol stores in vascular tissue: modulation by ultraviolet light, acetylcholine and ionomycin.. 560. 2007
Pharmacological characteristics of endothelium-derived hyperpolarizing factor-mediated relaxation of small mesenteric arteries from db/db mice.. 551. 2006
Effects of genetic background and null mutation of 5-HT1A receptors on basal and stress-induced body temperature: modulation by serotonergic and GABAA-ergic drugs.. 550. 2006
GR 63799X, an EP3 receptor agonist, induced S phase arrest and 3T6 fibroblast growth inhibition.. 529. 2005
Activation and inactivation of neuronal nitric oxide synthase: characterization of Ca(2+)-dependent [125I]Calmodulin binding.. 435. 2002
Novel selective hypotensive vasopressin peptides: cardiovascular and structure-activity-relationship studies.. 419. 2001
Nucleotide-evoked ion transport and [Ca(2+)](i) changes in normal and hyperhidrotic human sweat gland cells.. 403. 2000
Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374).. 383. 1999
Neuroprotection by the NMDA receptor-associated open-channel blocker memantine in a photothrombotic model of cerebral focal ischemia in neonatal rat.. 375. 1999
Ketoprofen S(+) enantiomer inhibits prostaglandin production and cell growth in 3T6 fibroblast cultures.. 370. 1999
High antagonist potency of GT-2227 and GT-2331, new histamine H3 receptor antagonists, in two functional models.. 351. 1998
Involvement of nitrosothiols, nitric oxide and voltage-gated K+ channels in photorelaxation of vascular smooth muscle.. 347. 1998
Chronic naltrexone differentially affects supraspinal delta-opioid receptor-mediated antinociception.. 345. 1998
Lecithinized superoxide dismutase attenuates phorbol myristate acetate-induced injury in isolated dog lung.. 344. 1998
Monitoring of antisense effects of oligonucleotides targeted to the neuropeptide Y Y1 receptor gene.. 330. 1997
Pyrrolidine dithiocarbamate inhibits immunostimulant-induced tetrahydrobiopterin synthesis in rat vascular smooth muscle.. 296. 1996
The effect of the irreversible mu-opioid receptor antagonist clocinnamox on morphine potency, receptor binding and receptor mRNA.. 287. 1995
Lipid A and the lipid A analogue anti-tumour compound ONO-4007 induce nitric oxide synthase in vitro and in vivo.. 291. 1995
Adaptive changes in the NMDA receptor complex in rat hippocampus after chronic treatment with CGP 39551.. 271. 1994
Hypoxic coronary vasodilatation and cGMP overproduction are blocked by a nitric oxide synthase inhibitor, but not by a guanylyl cyclase ANF receptor antagonist.. 256. 1994
Prolonged tolerance, dependence and abstinence following subcutaneous morphine pellet implantation in the rat.. 253. 1994
Pressor responses to the alpha 1-adrenoceptor agonist cirazoline: effects of captopril, phenoxybenzamine and nifedipine.. 251. 1994
Interleukin-1 contributes to the induction of nitric oxide synthase by endotoxin in vivo.. 250. 1993
The induction of nitric oxide synthase activity is inhibited by TGF-beta 1, PDGFAB and PDGFBB in vascular smooth muscle cells.. 216. 1992
Morphine-induced immunomodulation is not related to serum morphine concentrations.. 149. 1988
Pharmacological properties of a proenkephalin A-derived opioid peptide: BAM 18.. 138. 1987
Renal vasoconstrictive effect of kinins mediated by B1-kinin receptors.. 130. 1986
The effect of the calcium channel agonist, Bay K-8644 on human vascular smooth muscle.. 113. 1985
Two 5-HT receptors linked to adenylate cyclase in guinea pig hippocampus are discriminated by 5-carboxamidotryptamine and spiperone.. 109. 1985
Effects of phencyclidine on cardiac action potential: pH dependence and structure-activity relationships.. 88. 1983
Vascular responses of human skin to injection of substance P and mechanism of action.. 87. 1983
Heroin: analgesia, toxicity and disposition in the mouse.. 85. 1982
Adenosine triphosphate-evoked vascular changes in human skin: mechanism of action.. 76. 1981
In vivo intraneuronal MAO inhibition in rat brain SKF 64139, comparison to other potent PNMT inhibitors.. 70. 1981
Binding of 3H-beta-endorphin to rat brain membranes: characterization of opiate properties and interaction with ACTH.. 64. 1980
Cardiac anaphylaxis: SRS-A potentiates and extends the effects of released histamine.. 62. 1980
Selective impairment of atrioventricular conduction by 2-(2-pyridyl)-ethylamine and 2-(2-thiazolyl)-ethylamine, two histamine H1-receptor agonists.. 34. 1975
The influence of metiamide on ouabain cardiotoxicity.. 34. 1975
Effect of benzodiazepine compounds on brain amine metabolism.. 32. 1975
Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-and H2-receptor agonists and antagonists.. 30. 1975
Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-receptor antagonists.. 27. 1974
Cholinolytic action of phencyclidine derivatives.. 25. 1974
The diuretic effect of morphine in the chicken.. 5. 1968
Studies on the antidiuretic action of morphine in the rat.. 2. 1968
Glucocorticoid antagonists in neuropsychiatric [corrected] disorders. 2008
5-HT1A receptor knockout mouse as a genetic model of anxiety. 2003
Flavonoids attenuate cancer metabolism by modulating Lipid metabolism, amino acids, ketone bodies and redox state mediated by Nrf2. 2023
Interferon therapy in patients with SARS, MERS, and COVID-19: A systematic review and meta-analysis of clinical studies. 2021
Angiotensin-converting enzyme 2 (ACE2) receptor and SARS-CoV-2: Potential therapeutic targeting. 2020
Current approaches for neoadjuvant chemotherapy in breast cancer. 2013
Effects of deficiency of the G protein Gsα on energy and glucose homeostasis. 2011

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