JCO precision oncology
Journal
Overview
publication venue for
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Germline SMARCA4 Deletion as a Driver of Uterine Cancer: An Atypical Presentation.
2022
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Genomic Characterization of a RET Inhibitor-Resistant RET Fusion-Positive Lung Cancer by CSF Cell-Free DNA Hybrid Capture-Based Sequencing.
2020
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Lorlatinib and Bevacizumab Activity in ALK-Rearranged Lung Cancers After Lorlatinib Progression.
2020
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Acquisition of APOBEC Mutagenesis and Microsatellite Instability Signatures in the Development of Brain Metastases in Low-Grade, Early-Stage Endometrioid Endometrial Carcinoma.
2020
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FGFR1 Rearrangement Guides Diagnosis and Treatment of a Trilineage B, T, and Myeloid Mixed Phenotype Acute Leukemia.
2020
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Pathogenic Loss-of-Function Germline TERT Mutations in Patients With Solid Tumors.
2019
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Larotrectinib Demonstrates CNS Efficacy in TRK Fusion-Positive Solid Tumors.
2019
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Concordance in Oncogenic Alterations Between the Primary Tumor and Advanced Disease: Insights Into the Heterogeneity of Intrahepatic Cholangiocarcinoma..
8.
2024
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Cellular Mass Response to Therapy Correlates With Clinical Response for a Range of Malignancies..
8.
2024
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Germline Pathogenic Variants and Genetic Counseling by Ancestry in Patients With Epithelial Ovarian Cancer..
7.
2023
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Pan-Cancer Prevalence of Microsatellite Instability-High (MSI-H) Identified by Circulating Tumor DNA and Associated Real-World Clinical Outcomes..
7.
2023
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Targeted Molecular Profiling of Circulating Cell-Free DNA in Patients With Advanced Hepatocellular Carcinoma..
7.
2023
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Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors..
7.
2023
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Clinical and Genomic Features of Response and Toxicity to Sotorasib in a Real-World Cohort of Patients With Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer..
7.
2023
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Genomics of ERBB2-Positive Breast Cancer in Young Women Before and After Exposure to Chemotherapy Plus Trastuzumab..
7.
2023
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Cyclin-Dependent Kinase 4/6 Inhibitors Beyond Progression in Metastatic Breast Cancer: A Retrospective Real-World Biomarker Analysis..
7.
2023
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Prevalence and Clinical Implications of Mismatch Repair-Proficient Colorectal Cancer in Patients With Lynch Syndrome..
7.
2023
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Clinical Targeted Next-Generation Panel Sequencing Reveals MYC Amplification Is a Poor Prognostic Factor in Osteosarcoma..
7.
2023
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Pathway Alterations in Stage II/III Primary Melanoma..
7.
2023
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Clinicopathologic and Molecular Analysis of Normal Karyotype Therapy-Related and De Novo Acute Myeloid Leukemia: A Multi-Institutional Study by the Bone Marrow Pathology Group..
7.
2023
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Analysis of Circulating Tumor DNA to Predict Risk of Recurrence in Patients With Esophageal and Gastric Cancers..
6.
2022
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Germline Genetic and Treatment-Related Risk Factors for Diabetes Mellitus in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study and St Jude Lifetime Cohorts..
6.
2022
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Rare FGFR Oncogenic Alterations in Sequenced Pediatric Solid and Brain Tumors Suggest FGFR Is a Relevant Molecular Target in Childhood Cancer..
6.
2022
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Histology-Specific Prognostication for Radiation-Associated Soft Tissue Sarcoma..
6.
2022
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Addition of Germline Testing to Tumor-Only Sequencing Improves Detection of Pathogenic Germline Variants in Men With Advanced Prostate Cancer..
6.
2022
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Prospective Clinical Genomic Profiling of Ewing Sarcoma: ERF and FGFR1 Mutations as Recurrent Secondary Alterations of Potential Biologic and Therapeutic Relevance..
6.
2022
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SRC Family Kinase Inhibition Targets YES1 and YAP1 as Primary Drivers of Lung Cancer and as Mediators of Acquired Resistance to ALK and Epidermal Growth Factor Receptor Inhibitors..
6.
2022
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Matched Molecular Profiling of Cell-Free DNA and Tumor Tissue in Patients With Advanced Clear Cell Renal Cell Carcinoma..
6.
2022
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Longitudinal Shifts of Solid Tumor and Liquid Biopsy Sequencing Concordance in Metastatic Breast Cancer..
6.
2022
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Clinical and Genomic Characterization of Bladder Carcinomas With Glandular Phenotype..
6.
2022
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Genomic Landscape of Advanced Solid Tumors in Circulating Tumor DNA and Correlation With Tissue Sequencing: A Single Institution's Experience..
6.
2022
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Selpercatinib-Induced Hypothyroidism Through Off-Target Inhibition of Type 2 Iodothyronine Deiodinase..
6.
2022
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Mutant PPM1D- and TP53-Driven Hematopoiesis Populates the Hematopoietic Compartment in Response to Peptide Receptor Radionuclide Therapy..
6.
2022
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Germline Sequencing Improves Tumor-Only Sequencing Interpretation in a Precision Genomic Study of Patients With Pediatric Solid Tumor..
5.
2021
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Germline Testing Data Validate Inferences of Mutational Status for Variants Detected From Tumor-Only Sequencing..
5.
2021
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TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence..
5.
2021
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Differential Activity of PARP Inhibitors in BRCA1- Versus BRCA2-Altered Metastatic Castration-Resistant Prostate Cancer..
5.
2021
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Longitudinal Dynamics of Circulating Tumor Cells and Circulating Tumor DNA for Treatment Monitoring in Metastatic Breast Cancer..
5.
2021
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Tumor-Infiltrating Lymphocytes, Tumor Mutational Burden, and Genetic Alterations in Microsatellite Unstable, Microsatellite Stable, or Mutant POLE/POLD1 Colon Cancer..
5.
2021
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Differential Impact of ALK Mutations in Neuroblastoma..
5.
2021
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Prevalence and Characterization of Biallelic and Monoallelic NTHL1 and MSH3 Variant Carriers From a Pan-Cancer Patient Population..
5.
2021
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Utility of Serial cfDNA NGS for Prospective Genomic Analysis of Patients on a Phase I Basket Study..
5.
2021
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Identification of a Microsatellite Stable, EGFR-Mutant Lung Adenocarcinoma Developing in a Patient With Lynch Syndrome..
4.
2020
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Germ Cell Tumor Molecular Heterogeneity Revealed Through Analysis of Primary and Metastasis Pairs..
4.
2020
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Prospective Multicenter Study of Circulating Tumor Cell AR-V7 and Taxane Versus Hormonal Treatment Outcomes in Metastatic Castration-Resistant Prostate Cancer..
4.
2020
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Dickkopf-1 Can Lead to Immune Evasion in Metastatic Castration-Resistant Prostate Cancer..
4.
2020
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Genomic Alterations as Potential Therapeutic Targets in Extramammary Paget's Disease of the Vulva..
4.
2020
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Systematic Assessment of Tumor Purity and Its Clinical Implications..
4.
2020
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CNS Metastases in Patients With MET Exon 14-Altered Lung Cancers and Outcomes With Crizotinib..
4.
2020
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BRCA Mutations, Homologous DNA Repair Deficiency, Tumor Mutational Burden, and Response to Immune Checkpoint Inhibition in Recurrent Ovarian Cancer..
4.
2020
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P2RY8-CRLF2Fusion-Positive Acute Myeloid Leukemia With Myelodysplasia-Related Changes: Response to Novel Therapy..
4.
2020
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Circulating Tumor DNA Profiling of Advanced Biliary Tract Cancers..
3.
2019
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Identifying ERBB2 Activating Mutations in HER2-Negative Breast Cancer: Clinical Impact of Institute-Wide Genomic Testing and Enrollment in Matched Therapy Trials..
3.
2019
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Harmonization of Tumor Mutational Burden Quantification and Association With Response to Immune Checkpoint Blockade in Non-Small-Cell Lung Cancer..
3.
2019
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Genomic Characterization of ERBB2-Driven Biliary Cancer and a Case of Response to Ado-Trastuzumab Emtansine..
3.
2019
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Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer..
3.
2019
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Cancer-Specific Thresholds Adjust for Whole Exome Sequencing-based Tumor Mutational Burden Distribution..
3.
2019
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Real-World Outcomes of an Automated Physician Support System for Genome-Driven Oncology..
3.
2019
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Response to Selective RET Inhibition With LOXO-292 in a Patient With RET Fusion-Positive Lung Cancer With Leptomeningeal Metastases..
3.
2019
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Immunophenotype and Response to Immunotherapy of RET-Rearranged Lung Cancers..
3.
2019
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Acquired MET Exon 14 Alteration Drives Secondary Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in EGFR-Mutated Lung Cancer..
3.
2019
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Understanding inherited risk in unselected newly diagnosed patients with endometrial cancer..
3.
2019
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Harnessing Clinical Sequencing Data for Survival Stratification of Patients with Metastatic Lung Adenocarcinomas..
3.
2019
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Majority of B2M-Mutant and -Deficient Colorectal Carcinomas Achieve Clinical Benefit From Immune Checkpoint Inhibitor Therapy and Are Microsatellite Instability-High..
3.
2019
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Targeting HER2/neu Oncogene Overexpression With Ado-Trastuzumab Emtansine in the Treatment of Metastatic Salivary Gland Neoplasms: A Single-Institution Experience..
3.
2019
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Targeted Next-Generation Sequencing Reveals Clinically Actionable BRAF and ESR1 Mutations in Low-Grade Serous Ovarian Carcinoma..
2018.
2018
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Dramatic Response to Sequential BRAF Inhibition in BRAF V600E-Mutant Metastatic Lung Adenocarcinoma..
2.
2018
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Elevated Levels of BRAFV600 Mutant Circulating Tumor DNA and Circulating Hepatocyte Growth Factor Are Associated With Poor Prognosis in Patients With Metastatic Melanoma..
2.
2018
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Entrectinib in Two Pediatric Patients With Inflammatory Myofibroblastic Tumors Harboring ROS1 or ALK Gene Fusions..
2.
2018
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Acquired ALK and RET Gene Fusions as Mechanisms of Resistance to Osimertinib in EGFR-Mutant Lung Cancers..
2.
2018
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Evolving Intersection Between Inherited Cancer Genetics and Therapeutic Clinical Trials in Prostate Cancer: A White Paper From the Germline Genetics Working Group of the Prostate Cancer Clinical Trials Consortium..
2018.
2018
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Genomic Heterogeneity Underlies Mixed Response to Tropomyosin Receptor Kinase Inhibition in Recurrent Glioma..
2.
2018
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Impact of the SPOP Mutant Subtype on the Interpretation of Clinical Parameters in Prostate Cancer..
2018.
2018
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Clinicopathologic Features of Non-Small-Cell Lung Cancer Harboring an NTRK Gene Fusion..
2018.
2018
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BRCA2-Associated Prostate Cancer in a Patient With Spinal and Bulbar Muscular Atrophy..
2.
2018
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Real-Time Genomic Characterization of Metastatic Pancreatic Neuroendocrine Tumors Has Prognostic Implications and Identifies Potential Germline Actionability..
2018.
2018
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Acquired Resistance to Poly (ADP-ribose) Polymerase Inhibitor Olaparib in BRCA2-Associated Prostate Cancer Resulting From Biallelic BRCA2 Reversion Mutations Restores Both Germline and Somatic Loss-of-Function Mutations..
2.
2018
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Genomic Characterization of Upper-Tract Urothelial Carcinoma in Patients With Lynch Syndrome..
2018.
2018
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Specifying the True- and False-Positive Rates in Basket Trials..
1.
2017
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DNA Methylation-Based Classifier for Accurate Molecular Diagnosis of Bone Sarcomas..
2017.
2017
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Reliable Pan-Cancer Microsatellite Instability Assessment by Using Targeted Next-Generation Sequencing Data..
2017.
2017
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Successful Targeted Therapy of Refractory Pediatric ETV6-NTRK3 Fusion-Positive Secretory Breast Carcinoma..
2017.
2017
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PTEN Loss-of-Function Alterations Are Associated With Intrinsic Resistance to BRAF Inhibitors in Metastatic Melanoma..
1.
2017
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Next-Generation Rapid Autopsies Enable Tumor Evolution Tracking and Generation of Preclinical Models..
2017.
2017
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Personalized Medicine in the Oncology Clinic: Implementation and Outcomes of the Johns Hopkins Molecular Tumor Board..
2017.
2017
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Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making..
2017.
2017
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Plasma DNA-based molecular diagnosis, prognostication, and monitoring of patients with EWSR1 fusion-positive sarcomas..
2017.
2017
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OncoKB: A Precision Oncology Knowledge Base..
2017.
2017
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Persistent Severe Hyperlactatemia and Metabolic Derangement in Lethal SDHB-Mutated Metastatic Kidney Cancer: Clinical Challenges and Examples of Extreme Warburg Effect.
2017
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Intermittent Treatment With MEK Inhibitors in Patients With Oncogenic RAF-Driven Tumors: A Potential Strategy to Manage Toxicity and Maintain Efficacy.
2018
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Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care.
2022
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Impact of Circulating Tumor DNA-Based Detection of Molecular Residual Disease on the Conduct and Design of Clinical Trials for Solid Tumors.
2022
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