Biochemical and biophysical research communications

publication venue for

HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320.. 691. 2023
TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization.. 531. 2020
Therapeutic efficacy of modified anti-miR21 in metastatic prostate cancer.. 529. 2020
Uremic toxins promote accumulation of oxidized protein and increased sensitivity to hydrogen peroxide in endothelial cells by impairing the autophagic flux.. 523. 2019
Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13.. 521. 2019
Resveratrol loaded oxidized mesoporous carbon nanoparticles: A promising tool to treat triple negative breast cancer.. 519. 2019
FGF8 and FGFR3 are up-regulated in hypertrophic chondrocytes: Association with chondrocyte death in deep zone of Kashin-Beck disease.. 500. 2018
Carbon monoxide regulates glycolysis-dependent NLRP3 inflammasome activation in macrophages.. 493. 2017
CD40 agonist converting CTL exhaustion via the activation of the mTORC1 pathway enhances PD-1 antagonist action in rescuing exhausted CTLs in chronic infection.. 484. 2017
A telomerase-derived peptide regulates reactive oxygen species and hepatitis C virus RNA replication in HCV-infected cells via heat shock protein 90.. 471. 2016
Threonine 576 residue of amyloid-β precursor protein regulates its trafficking and processing.. 467. 2015
Targeted disruption of fibrinogen like protein-1 accelerates hepatocellular carcinoma development.. 465. 2015
Detection of huntingtin exon 1 phosphorylation by Phos-Tag SDS-PAGE: Predominant phosphorylation on threonine 3 and regulation by IKKβ.. 463. 2015
A PKM2 signature in the failing heart.. 459. 2015
C-terminal motif within Sec7 domain regulates guanine nucleotide exchange activity via tuning protein conformation.. 446. 2014
CD19 target-engineered T-cells accumulate at tumor lesions in human B-cell lymphoma xenograft mouse models.. 438. 2013
Development of temperature-sensitive mutants of the Drosophila melanogaster P-TEFb (Cyclin T/CDK9) heterodimer using yeast two-hybrid screening.. 433. 2013
Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family.. 430. 2012
Phosphorylation of α-synuclein is crucial in compensating for proteasomal dysfunction.. 424. 2012
Relevance of the OCT1 transporter to the antineoplastic effect of biguanides.. 414. 2011
Glutathione is essential for early embryogenesis--analysis of a glutathione synthetase knockout mouse.. 412. 2011
Effects of 3T3 adipocytes on interleukin-6 expression and insulin signaling in L6 skeletal muscle cells.. 410. 2011
Augmented oxygen-mediated transcriptional activation of cytochrome P450 (CYP)1A expression and increased susceptibilities to hyperoxic lung injury in transgenic mice carrying the human CYP1A1 or mouse 1A2 promoter in vivo.. 407. 2011
Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis.. 407. 2011
The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis.. 405. 2011
An ELISA-based method to quantify osteocalcin carboxylation in mice.. 397. 2010
The prostaglandin transporter PGT transports PGH(2).. 395. 2010
Overexpression of F(0)F(1)-ATP synthase alpha suppresses mutant huntingtin aggregation and toxicity in vitro.. 390. 2009
Kinase suppressor of Ras transphosphorylates c-Raf-1.. 390. 2009
Abnormal serum concentrations of proteins in Parkinson's disease.. 389. 2009
Inducing rigid local structure around the zinc-binding region by hydrophobic interactions enhances the homotrimerization and apoptotic activity of zinc-free TRAIL.. 362. 2007
Carbon monoxide dehydrogenase in mycobacteria possesses a nitric oxide dehydrogenase activity.. 362. 2007
Particulate and soluble adenylyl cyclases participate in the sperm acrosome reaction.. 358. 2007
Chip-based detection of hepatitis C virus using RNA aptamers that specifically bind to HCV core antigen.. 358. 2007
Differential regulation of protein phosphatase-1(I) by neurabin.. 358. 2007
Imaging of multiple mRNA targets using quantum dot based in situ hybridization and spectral deconvolution in clinical biopsies.. 348. 2006
Characterization of an equine mannose-binding lectin and its roles in disease.. 343. 2006
Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson's disease.. 342. 2006
A new method for analysis of mitochondrial DNA point mutations and assess levels of heteroplasmy.. 342. 2006
Amyloid fibril formation by macrophage migration inhibitory factor.. 338. 2005
Tetradecanoyl phorbol acetate induces expression of Toll-like receptor 2 in U937 cells: involvement of PKC, ERK, and NF-kappaB.. 328. 2005
Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells.. 323. 2004
Up-regulation of human beta-defensin 2 by interleukin-1beta in A549 cells: involvement of PI3K, PKC, p38 MAPK, JNK, and NF-kappaB.. 320. 2004
Potential for germ line transmission after intramyocardial gene delivery by adeno-associated virus.. 313. 2004
A new human peptide deformylase inhibitable by actinonin.. 312. 2003
Increased severity of reperfusion arrhythmias in mouse hearts lacking histamine H3-receptors.. 306. 2003
Compromised calnexin function in calreticulin-deficient cells.. 304. 2003
Regulation of myeloma cell growth through Akt/Gsk3/forkhead signaling pathway.. 297. 2002
Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression.. 296. 2002
The effects of centrally administered apelin-13 on food intake, water intake and pituitary hormone release in rats.. 291. 2002
A significant role for the heme oxygenase-1 gene in endothelial cell cycle progression.. 291. 2002
Sequence analysis of the entire mitochondrial genome in Parkinson's disease.. 290. 2002
CEA is the major PHA-L-reactive glycoprotein in colon carcinoma cell lines and tumors: relationship between K-ras activation and beta1-6 branching of N-linked carbohydrate on CEA.. 273. 2000
Characterization of lectin resistant cell populations derived from human colon carcinoma: correlation of K-Ras with beta1-6 branching of N-linked carbohydrate and CEA production.. 259. 1999
Glycated serum albumin-induced nitric oxide production in vascular smooth muscle cells by nuclear factor kappaB-dependent transcriptional activation of inducible nitric oxide synthase.. 259. 1999
Changes in expression of the 44-kilodalton outer surface membrane antigen (p44 kD) for monitoring progression of infection and antimicrobial susceptibility of the human granulocytic ehrlichiosis (HGE) agent in HL-60 cells.. 257. 1999
Homologue scanning mutagenesis of heregulin reveals receptor specific binding epitopes.. 251. 1998
Renin inhibits the vasorelaxation induced by nitroso albumin.. 250. 1998
Radiation-induced micronuclei formation in human breast cancer cells: dependence on serum and cell cycle distribution.. 237. 1997
Cellular changes and induction of apoptosis in human promyelocytic HL-60 cells infected with the agent of human granulocytic ehrlichiosis (HGE).. 232. 1997
Biochemical evidence for orphanin FQ/nociceptin receptor heterogeneity in mouse brain.. 230. 1997
IL-6 stimulation of insulin-like growth factor binding protein (IGFBP)-1 production.. 228. 1996
Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.. 219. 1996
Effect of lipopolysaccharide treatment in vivo on tissue expression of argininosuccinate synthetase and argininosuccinate lyase mRNAs: relationship to nitric oxide synthase.. 215. 1995
Beta 1-6 branching of N-linked carbohydrate is associated with K-ras mutation in human colon carcinoma cell lines.. 212. 1995
Modular structure of neuronal nitric oxide synthase: localization of the arginine binding site and modulation by pterin.. 210. 1995
Substance P and bradykinin are natural inhibitors of CD13/aminopeptidase N.. 208. 1995
Nitric oxide activates metalloprotease enzymes in articular cartilage.. 206. 1995
Regulation of transforming growth factor-beta 1 (TGF-beta 1) expression with a novel TGF-beta 1 complementary DNA.. 204. 1994
The tumor protein MAGE-1 is located in the cytosol of human melanoma cells.. 204. 1994
Loss of heterozygosity and decreased expression of NME genes correlate with teratomatous differentiation in human male germ cell tumors.. 202. 1994
The primary structure of a human MAP kinase activated protein kinase 2.. 200. 1994
Attenuation of the neurotoxic effect of A beta amyloid peptide by apolipoprotein E.. 199. 1994
The association between CD45 and lck does not require CD4 or CD8 and is independent of T cell receptor stimulation.. 198. 1994
Nitrite production by stimulated human polymorphonuclear leukocytes supplemented with azide and catalase.. 197. 1993
GTP cyclohydrolase I mRNA is induced by LPS in vascular smooth muscle: characterization, sequence and relationship to nitric oxide synthase.. 195. 1993
Endothelin-1 and endothelin receptor mRNA expression in normal and atherosclerotic human arteries.. 191. 1993
Myocardial phosphoinositides do not share the same fatty acid profile.. 191. 1993
Cholesterol enrichment of arterial smooth muscle cells upregulates cytokine-induced nitric oxide synthesis.. 191. 1993
Fucoidan is a non-anticoagulant inhibitor of intimal hyperplasia.. 184. 1992
Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells.. 184. 1992
The role of phosphorylation in development of tight junctions in cultured renal epithelial (MDCK) cells.. 181. 1991
Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages.. 178. 1991
Complementary DNA sequence of human neutrophil azurocidin, an antibiotic with extensive homology to serine proteases.. 177. 1991
Arachidonic acid metabolism by dioxin-induced cytochrome P-450: a new hypothesis on the role of P-450 in dioxin toxicity.. 172. 1990
Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis.. 172. 1990
Message amplification phenotyping of an inherited delta-aminolevulinate dehydratase deficiency in a family with acute hepatic porphyria.. 172. 1990
Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine.. 170. 1990
FAD and GSH participate in macrophage synthesis of nitric oxide.. 168. 1990
Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells.. 166. 1990
Phorbol ester-mediated induction of HIV-1 from a chronically infected promonocyte clone: blockade by protein kinase inhibitors and relationship to tat-directed trans-activation.. 166. 1990
Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells.. 165. 1989
The distribution of glycosyl-phosphatidylinositol anchored proteins is differentially regulated by serum and insulin.. 164. 1989
Observation of arginyl-deoxyoligonucleotide interactions in Taq I endonuclease by detection of specific 1H NMR signals from 140kD [N eta 1, N eta 2, 15N Arg]Taq I/oligomer complexes.. 164. 1989
L-arginine availability determines the duration of acetylcholine-induced systemic vasodilation in vivo.. 163. 1989
Inhibition of ubiquitin-dependent proteolysis by des-Gly-Gly-ubiquitin: implications for the mechanism of polyubiquitin synthesis.. 162. 1989
Synthesis of nitrogen oxides from L-arginine by macrophage cytosol: requirement for inducible and constitutive components.. 161. 1989
NG-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo?. 160. 1989
The insulin-like growth factor binding protein BP-25 is expressed by human breast cancer cells.. 158. 1989
A23187 and protein kinase C activators stimulate phosphatidylinositol metabolism and prostaglandin synthesis in a human lung cancer cell line.. 156. 1988
Effect of retinoic acid on cAMP dependent protein phosphorylation in psoriatic fibroblasts.. 156. 1988
Fura-2 used as a probe to show elevated intracellular free calcium in platelets of Dahl-sensitive rats fed a high salt diet.. 154. 1988
Immunochemical detection of cytochrome P450C-M/F and NADPH-cytochrome P450 reductase in rat liver and kidney.. 150. 1988
Tin-protoporphyrin inhibits heme oxygenase and prevents the decline in hepatic heme and cytochrome P-450 contents produced in nude mice by tumor transplantation.. 150. 1988
Isolation and partial characterization of plasma membrane fatty acid binding proteins from myocardium and adipose tissue and their relationship to analogous proteins in liver and gut.. 148. 1987
Partial purification of cytochrome P450 from rat brain and demonstration of estradiol hydroxylation.. 147. 1987
Mitogenic activity and inositide metabolism in thrombin-stimulated pig aorta endothelial cells.. 145. 1987
Stimulation of procollagenase synthesis parallels increases in cellular procollagenase mRNA in human articular chondrocytes exposed to recombinant interleukin 1 beta or phorbol ester.. 144. 1987
Drug metabolism by the human hepatoma cell, Hep G2.. 143. 1987
Phospholipase C-diglyceride lipase is a major pathway for arachidonic acid release in macrophages.. 141. 1986
Arachidonic acid releasing systems in pig aorta endothelial cells.. 139. 1986
Apolipoprotein E-mediated binding of hypertriglyceridemic very low density lipoproteins to isolated low density lipoprotein receptors detected by ligand blotting.. 139. 1986
Binding of apoA-IV-phospholipid complexes to plasma membranes of rat liver.. 139. 1986
The helical hydrophobic moment avoids prolines in phospholipid-binding proteins.. 139. 1986
Role of methionine-1 in ubiquitin conformation and activity.. 138. 1986
Intracellular Ca2+ requirements for zymosan-stimulated phosphoinositide hydrolysis in mouse peritoneal macrophages.. 134. 1986
Abnormal interaction of the human apolipoprotein A-I variant [Lys107----0] with high density lipoproteins.. 133. 1985
The human apolipoprotein B-100 gene: a highly polymorphic gene that maps to the short arm of chromosome 2.. 133. 1985
Ganglioside GD2 specificity of monoclonal antibodies to human neuroblastoma cell.. 127. 1985
The potent induction of intestinal heme oxygenase by the organotin compound, bis(tri-n-butyltin)oxide.. 119. 1984
In vitro transfer of phosphatidylcholines and their ether analogs by a human and rat plasma exchange factor.. 119. 1984
Identification of proapoa-I in rat lymph and plasma: metabolic conversion to "mature" apoA-I.. 116. 1983
Apolipoprotein-E degradation in human very low density lipoproteins by plasma protease(s): chemical and biological consequences.. 109. 1982
Interaction of vitamin E with saturated phospholipid bilayers.. 106. 1982
Fluorescent cholesteryl esters in the core of low density lipoprotein.. 105. 1982
Human plasma high density apolipoprotein A-I: effect of protein-protein interactions on the spontaneous formation of a lipid-protein recombinant.. 99. 1981
Phosphorylation of the IgE receptor from ionophore A23187 stimulated intact rat mast cells.. 98. 1981
Lipolysis of ApoC-II deficient very low density lipoproteins: enhancement of lipoprotein lipase action by synthetic fragments of apoC-II.. 89. 1979
Insulin stimulation of amino acid transport in isolated rat hepatocytes is independent of hormone internalization.. 88. 1979
Apo B concentration in the normal human aorta.. 85. 1978
Lipoprotein-apoprotein exchange in aqueous systems: relevance to the occurrence of apoA-I and apoC proteins in a common particle.. 85. 1978
Release of low density lipoprotein receptors from human fibroblasts or HeLa cells by tryptic digestion.. 84. 1978
7,8-Benzoflavone stimulates the metabolic activation of aflatoxin B1 to mutagens by human liver.. 82. 1978
The cyanogen bromide peptides of the apoprotein of low density lipoprotein (ApoB): its molecular weight from a chemical view.. 81. 1978
Atomic coordinates for triose phosphate isomerase from chicken muscle.. 72. 1976
Inhibition of chemical induction of porphyrin synthesis in chick embryo liver cells by partially purified human chorionic gonadotropin.. 68. 1976
Effects of maleylation on the lipid-binding and immunochemical properties of human plasma high density apolipoprotein-A-II.. 61. 1974
The requirement for lipid fluidity in the formation and structure of lipoproteins: thermotropic analysis of apolipoprotein-alanine binding to dimyristoyl phosphatidylcholine.. 60. 1974
The interaction of tetraiodofluorescein with aspartate transcarbamylase.. 55. 1973
Isolation of a helical, lipid-binding fragment from the human plasma high density lipoprotein, apoLP GLN-I.. 49. 1972
Identification of the lipid-binding cyanogen bromide fragment from the cystine-containing high density apolipoprotein, APOLP-GLN-II.. 49. 1972
Interaction between proflavine and deoxyribonucleic acid influence of DNA base composition.. 47. 1972
Stimulation of lac mRNA synthesis by cyclic AMP in cell free extracts of Escherichia coli.. 38. 1970
Application of electron spin resonance to the study of the structure of human serum lipoproteins.. 37. 1969
The structure and properties of human beta-lipoprotein and beta-apoprotein.. 31. 1968
Human serum beta-lipoprotein: preparation and properties of a delipidated, soluble derivative.. 31. 1968
The nature of an amino acid residue at the active center of fumarase.. 28. 1967
Induction of fructose-1,6-diphosphatase activity in Escherichia coli.. 9. 1962
Emerging roles of Lipasin as a critical lipid regulator. 2013

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