medRxiv : the preprint server for health sciences
Journal
Overview
publication venue for
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Leveraging DNA methylation to create Epigenetic Biomarker Proxies that inform clinical care: A new framework for Precision Medicine.
2024
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A Multicenter Retrospective Observational Cohort Study of Seizure Freedom before Lennox-Gastaut Syndrome (the "Gap"). Opportunities for Prevention.
2024
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Negative BOLD Responses Surpass Positive Responses in Task Specificity, Reflecting Neural Reconfigurations Better Than Functional Connectivity.
2024
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Genome-wide studies define new genetic mechanisms of IgA vasculitis.
2024
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Alpha coherence is a network signature of cognitive recovery from disorders of consciousness.
2024
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Prevalence and Determinants of Prehospital Impression of Stroke in Ischemic Stroke Patients.
2024
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Measurable imaging-based changes in enhancement of intrahepatic cholangiocarcinoma after radiotherapy reflect physical mechanisms of response.
2024
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Early drivers of clonal hematopoiesis shape the evolutionary trajectories of de novo acute myeloid leukemia.
2024
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Gene Signature for Predicting Metastasis in Prostate Cancer Using Primary Tumor Expression Profiles.
2024
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Longer interval between maternal RSV vaccination and birth increases placental transfer efficiency.
2024
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Using a mixed-reality headset to elicit and track clinically relevant movement in the clinic.
2024
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Intratumoral T-cell composition predicts epcoritamab-based treatment efficacy in B-cell non-Hodgkin lymphomas.
2024
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Somatic instability of the FGF14 -SCA27B GAA•TTC repeat reveals a marked expansion bias in the cerebellum.
2024
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Complement 3a Receptor 1 on Macrophages and Kupffer cells is not required for the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease.
2024
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Clinical Utility of the Molecular Microscope Diagnostic System in a Real-World Transplant Cohort: Moving Towards a New Paradigm.
2024
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Skeletal effects of sleeve gastrectomy, by sex and menopausal status and in comparison to Roux-en-Y gastric bypass surgery.
2024
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Predictors of Clinical Outcomes among People with HIV and Tuberculosis Symptoms after Rapid Treatment Initiation in Haiti.
2024
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Emergence of transmissible SARS-CoV-2 variants with decreased sensitivity to antivirals in immunocompromised patients with persistent infections.
2024
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Transferrin receptor-based circulating tumor cell enrichment provides a snapshot of the molecular landscape of solid tumors and correlates with clinical outcomes.
2024
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Differences in HIV-1 reservoir size, landscape characteristics and decay dynamics in acute and chronic treated HIV-1 Clade C infection.
2024
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ACK1 and BRK non-receptor tyrosine kinase deficiencies are associated with familial systemic lupus and involved in efferocytosis.
2024
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Pediatric Gastrointestinal Outcomes During the Post-Acute Phase of COVID-19.
2024
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A Natural History Study of Timothy Syndrome.
2024
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Effect of Montelukast vs Placebo on Time to Sustained Recovery in Outpatients with COVID-19: The ACTIV-6 Randomized Clinical Trial.
2024
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Multiomic foundations of human prefrontal cortex tissue function.
2024
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Preliminary findings from the Dynamics of the Immune Responses to Repeat Influenza Vaccination Exposures (DRIVE I) Study: a Randomized Controlled Trial.
2024
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Cost-Effectiveness of Screening Asymptomatic Carotid Stenosis by Atherosclerotic Cardiovascular Risk.
2024
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United States Provider Experiences with Telemedicine for Hepatitis C Treatment: A Nationwide Survey.
2024
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HIV BG505 SOSIP.664 trimer with 3M-052-AF/alum induces human autologous tier-2 neutralizing antibodies.
2024
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ALLIANCE A022104/NRG-GI010: The Janus Rectal Cancer Trial: a randomized phase II/III trial testing the efficacy of triplet versus doublet chemotherapy regarding clinical complete response and disease-free survival in patients with locally advanced rectal cancer.
2024
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Long-Term Follow-Up Defines the Population That Benefits from Early Interception in a High-Risk Smoldering Multiple Myeloma Clinical Trial Using the Combination of Ixazomib, Lenalidomide, and Dexamethasone.
2024
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Computational Deconvolution of Cell Type-Specific Gene Expression in COPD and IPF Lungs Reveals Disease Severity Associations.
2024
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The Burden of Cancer and Pre-cancerous Conditions Among Transgender Individuals in a Large Healthcare Network.
2024
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Quantitative transport mapping of multi-delay arterial spin labeling MRI detects early blood perfusion alteration in Alzheimer's disease.
2024
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Risk factors for breast cancer subtypes by race and ethnicity: A scoping review of the literature.
2024
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Translational modeling-based evidence for enhanced efficacy of standard-of-care drugs in combination with anti-microRNA-155 in non-small-cell lung cancer.
2024
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Corticosteroids for infectious critical illness: A multicenter target trial emulation stratified by predicted organ dysfunction trajectory.
2024
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Circulating CD4+ T cells in people with HIV and history of pulmonary tuberculosis have more intact HIV DNA.
2024
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Utility of skin tone on pulse oximetry in critically ill patients: a prospective cohort study.
2024
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Increased Frequency of Clonal Hematopoiesis of Indeterminate Potential in Bloom Syndrome Probands and Carriers.
2024
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Discovery of Oncogenic Mediator Genes in Rectal Cancer Chemotherapy Response using Gene Expression Data from Matched Tumor and Patient-Derived Organoid.
2024
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Enhancing Chemotherapy Response Prediction via Matched Colorectal Tumor-Organoid Gene Expression Analysis and Network-Based Biomarker Selection.
2024
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Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
2024
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Effect of Paxlovid Treatment on Long COVID Onset: An EHR-Based Target Trial Emulation from N3C.
2024
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Validation of International Classification of Diseases, 10 th Edition, Clinical Modification (ICD-10-CM) Code I68.0 for Cerebral Amyloid Angiopathy.
2024
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Genome-wide SNP-sex interaction analysis of susceptibility to idiopathic pulmonary fibrosis.
2024
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First-in-human imaging with [89Zr]Zr-DFO-SC16.56 anti-DLL3 antibody in patients with high-grade neuroendocrine tumors of the lung and prostate.
2024
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Investigative needle core biopsies for multi-omics in Glioblastoma.
2023
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Potential Utility of C-reactive Protein for Tuberculosis Risk Stratification among Patients with Non-Meningitic Symptoms at HIV Diagnosis in Low- and Middle-Income Countries.
2023
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Urinary Cell Gene Signature of Acute Rejection in Kidney Allografts.
2023
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Normative Values of Echocardiographic Chamber Size and Function in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis.
2023
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A Modified Mediterranean Ketogenic Diet mitigates modifiable risk factors of Alzheimer's Disease: a serum and CSF-based metabolic analysis.
2023
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SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease.
2023
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Clinical practice recommendations on lipoprotein apheresis for children with homozygous familial hypercholesterolemia: an expert consensus statement from ERKNet and ESPN.
2023
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Real-world Effectiveness of BNT162b2 Against Infection and Severe Diseases in Children and Adolescents.
2023
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Cost-effectiveness of broadly neutralizing antibodies for infant HIV prophylaxis in settings with high HIV burdens: a simulation modeling study.
2023
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Validation and Responsiveness of the English version of the Chemotherapy-Induced Alopecia Distress Scale (CADS) in Breast Cancer Patients.
2023
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Acute myeloid leukemia with mixed phenotype is characterized by stemness transcriptomic signatures and limited lineage plasticity.
2023
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The qMini assay identifies an overlooked class of splice variants.
2023
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Determinants of mosaic chromosomal alteration fitness.
2023
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Subarachnoid Hemorrhage Trials: Cutting, Sliding, or Keeping mRS Scores and WFNS Grades.
2023
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Trends in Healthcare Service Disruptions and Associations with COVID-19 Outcomes among Patients with SMI vs. Non-SMI during COVID-19.
2023
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Usage of Mineralocorticoids and Isotonic Crystalloids in Subarachnoid Hemorrhage Patients in the United States.
2023
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A Retrospective Case Study of Successful Translational Research: Cardiovascular Disease Risk Assessment, Experiences in Community Engagement.
2023
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Longitudinal Trajectories of Symptom Change During Antidepressant Treatment Among Managed Care Patients with Co-Occurring Depression and Anxiety.
2023
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Microstructure-Informed Myelin Mapping (MIMM) from Gradient Echo MRI using Stochastic Matching Pursuit.
2023
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In utero human cytomegalovirus infection expands NK cell-like FcγRIII-expressing CD8+ T cells that mediate antibody-dependent functions.
2023
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Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data.
2023
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Machine Learning Reveals Synovial Fibroblast Genes Associated with Pain Affect Sensory Nerve Growth in Rheumatoid Arthritis.
2023
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Timing dependent synergies between motor cortex and posterior spinal stimulation in humans.
2023
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Pulmonary Artery Pressures and Mortality during VA ECMO: An ELSO Registry Analysis.
2023
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The Relationship of Duffy Gene Polymorphism, High Sensitivity C-Reactive Protein, and Long-term Outcomes.
2023
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Identification of Outcome-Oriented Progression Subtypes from Mild Cognitive Impairment to Alzheimer's Disease Using Electronic Health Records.
2023
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Instability in longitudinal sleep duration predicts cognitive impairment in aged participants of the Seattle Longitudinal Study.
2023
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Natural Language Processing Can Automate Extraction of Barrett's Esophagus Endoscopy Quality Metrics.
2023
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Measuring up: A Comparison of Tapestation 4200 and Bioanalyzer 2100 as Measurement Tools for RNA Quality in Postmortem Human Brain Samples.
2023
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From Answers to Insights: Unveiling the Strengths and Limitations of ChatGPT and Biomedical Knowledge Graphs.
2023
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Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.
2023
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Integrating 4 Measures to Evaluate Physical Function in Patients with Cancer (In4M): Protocol for a prospective study.
2023
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Circulating tumor DNA association with residual cancer burden after neoadjuvant chemotherapy in triple-negative breast cancer in TBCRC 030.
2023
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A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection.
2023
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Omicron infection of vaccinated individuals enhances neutralizing immunity against the Delta variant.
2022
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SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity.
2021
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The emergence and ongoing convergent evolution of the N501Y lineages coincides with a major global shift in the SARS-CoV-2 selective landscape.
2021
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Hyperglycemia in Acute COVID-19 is Characterized by Adipose Tissue Dysfunction and Insulin Resistance.
2021
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Do Pandemics Obey the Elliott Wave Principle of Financial Markets?
2021
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Dysregulated immunity in SARS-CoV-2 infected pregnant women.
2020
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Innate immunity plays a key role in controlling viral load in COVID-19: mechanistic insights from a whole-body infection dynamics model.
2020
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Test sensitivity is secondary to frequency and turnaround time for COVID-19 surveillance.
2020
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WT1 Tumor Antigen is Overexpressed in Kaposi Sarcoma and is Regulated by KSHV vFLIP
2021
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