publication venue for
- GLUT1 overexpression enhances CAR T cell metabolic fitness and anti-tumor efficacy. 2024
- TLR9-independent CD8+ T Cell Responses in Hepatic AAV Gene Transfer Through IL-1R1-MyD88 Signaling. 2023
- Combination HSCT and intravenous AAV-mediated gene therapy in a canine model proves pivotal for translation of Krabbe disease therapy. 2023
- Casein kinase 2 activity is a host restriction factor for AAV transduction. 2023
- Ectopic clotting factor VIII expression and misfolding in hepatocytes as a cause for hepatocellular carcinoma. 2022
- WNT-modulating gene silencers as a gene therapy for osteoporosis, bone fracture, and critical-sized bone defects. 2022
- IL-15 Blockade and Rapamycin Rescue Multifactorial Loss of Factor VIII from AAV-Transduced Hepatocytes in Hemophilia A Mice. 2022
- Globin vector regulatory elements are active in early hematopoietic progenitor cells.. 30. 2022
- Dichotomous effects of cellular expression of STAT3 on tumor growth of HNSCC.. 30. 2021
- Direct Reprogramming Induces Vascular Regeneration Post Muscle Ischemic Injury. 2021
- Incorporation of bacterial immunoevasins to protect cell therapies from host antibody-mediated immune rejection. 2021
- CD8+ T Cells Impact Rising PSA in Biochemically Relapsed Cancer Patients Using Immunotherapy Targeting Tumor-Associated Antigens.. 28. 2020
- Computational Analysis Concerning the Impact of DNA Accessibility on CRISPR-Cas9 Cleavage Efficiency.. 28. 2019
- Preclinical Evaluation of ADVM-022, a Novel Gene Therapy Approach to Treating Wet Age-Related Macular Degeneration.. 27. 2018
- Low-Dose Radiation Conditioning Enables CAR T Cells to Mitigate Antigen Escape.. 26. 2018
- Autologous CD19-Targeted CAR T Cells in Patients with Residual CLL following Initial Purine Analog-Based Therapy.. 26. 2018
- HIV-Specific T Cells Generated from Naive T Cells Suppress HIV In Vitro and Recognize Wide Epitope Breadths.. 26. 2018
- Development and Evaluation of an Optimal Human Single-Chain Variable Fragment-Derived BCMA-Targeted CAR T Cell Vector.. 26. 2018
- Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy.. 26. 2018
- The Balance between CD8+ T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose.. 25. 2017
- In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy.. 24. 2016
- Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid.. 24. 2016
- Blocking the adhesion cascade at the premetastatic niche for prevention of breast cancer metastasis.. 23. 2015
- Enhancing antitumor efficacy of chimeric antigen receptor T cells through constitutive CD40L expression.. 23. 2015
- Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma.. 21. 2013
- Targeted coating with antigenic peptide renders tumor cells susceptible to CD8(+) T cell-mediated killing.. 21. 2012
- A TLR and non-TLR mediated innate response to lentiviruses restricts hepatocyte entry and can be ameliorated by pharmacological blockade.. 20. 2012
- Novel therapies, high-risk pediatric research, and the prospect of benefit: learning from the ethical disagreements.. 20. 2012
- Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs.. 19. 2011
- Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood-brain barrier endothelial cells in vitro.. 19. 2010
- Inhibition of choroidal neovascularization in a nonhuman primate model by intravitreal administration of an AAV2 vector expressing a novel anti-VEGF molecule.. 19. 2010
- Absence of systemic immune response to adenovectors after intraocular administration to children with retinoblastoma.. 18. 2010
- Transient demyelination increases the efficiency of retrograde AAV transduction.. 18. 2010
- Overexpression of sonic Hedgehog in the lung mimics the effect of lung injury and compensatory lung growth on pulmonary Sca-1 and CD34 positive cells.. 18. 2009
- Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication.. 18. 2009
- Phase I study of H5.020CMV.PDGF-beta to treat venous leg ulcer disease.. 17. 2009
- Treatment with cyclooxygenase-2 inhibitors enables repeated administration of vaccinia virus for control of ovarian cancer.. 17. 2009
- Sonic hedgehog expands diaphyseal trabecular bone altering bone marrow niche and lymphocyte compartment.. 17. 2009
- Enhancement of oncolytic properties of recombinant newcastle disease virus through antagonism of cellular innate immune responses.. 17. 2009
- A herpes oncolytic virus can be delivered via the vasculature to produce biologic changes in human colorectal cancer.. 17. 2008
- Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma.. 16. 2008
- Erythroid-specific human factor IX delivery from in vivo selected hematopoietic stem cells following nonmyeloablative conditioning in hemophilia B mice.. 16. 2008
- Mechanisms of immunization against cancer using chimeric antigens.. 16. 2008
- Rapid/sustained anti-anthrax passive immunity mediated by co-administration of Ad/AAV.. 16. 2007
- Efficient retrograde neuronal transduction utilizing self-complementary AAV1.. 16. 2007
- Safety and immunogenicity of tyrosinase DNA vaccines in patients with melanoma.. 15. 2007
- Human matrix metalloproteinase-8 gene delivery increases the oncolytic activity of a replicating adenovirus.. 15. 2007
- Lentivirally transduced recipient-derived dendritic cells serve to ex vivo expand functional FcRgamma-sufficient double-negative regulatory T cells.. 15. 2007
- Nectin-1 expression by squamous cell carcinoma is a predictor of herpes oncolytic sensitivity.. 15. 2007
- Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 rhesus macaque-derived adeno-associated virus vector.. 15. 2006
- Modulation of adenoviral transduction in vitro and in vivo by hyaluronan and its receptor CD44.. 15. 2006
- Biological response determinants in HSV-tk + ganciclovir gene therapy for prostate cancer.. 13. 2006
- High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses.. 13. 2005
- Alteration of splicing signals in a genomic/cDNA hybrid VEGF gene to modify the ratio of expressed VEGF isoforms enhances safety of angiogenic gene therapy.. 12. 2005
- Enhanced efficacy of cholesterol-minus sonic hedgehog in postnatal skin.. 12. 2005
- High-resolution imaging of bone precursor cells within the intact bone marrow cavity of living mice.. 12. 2005
- Passive immunotherapy for anthrax toxin mediated by an adenovirus expressing an anti-protective antigen single-chain antibody.. 11. 2005
- Intrapleural administration of a serotype 5 adeno-associated virus coding for alpha1-antitrypsin mediates persistent, high lung and serum levels of alpha1-antitrypsin.. 10. 2004
- Oncolytic vaccinia virus expressing the human somatostatin receptor SSTR2: molecular imaging after systemic delivery using 111In-pentetreotide.. 10. 2004
- Adenovirus-mediated transfer of a minigene expressing multiple isoforms of VEGF is more effective at inducing angiogenesis than comparable vectors expressing individual VEGF cDNAs.. 9. 2004
- In vivo trans-splicing of 5' and 3' segments of pre-mRNA directed by corresponding DNA sequences delivered by gene transfer.. 8. 2003
- Cationic lipid and polymer-based gene delivery to human pancreatic islets.. 7. 2003
- Impact of preimmunization on adenoviral vector expression and toxicity in a subcutaneous mouse cancer model.. 6. 2002
- In vivo enhanced expression of patched dampens the sonic hedgehog pathway.. 6. 2002
- Effect of adenovirus gene transfer vectors on the immunologic functions of mouse dendritic cells.. 5. 2002
- Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle.. 4. 2001
- TNFalpha and IFNgamma induced by innate anti-adenoviral immune responses inhibit adenovirus-mediated transgene expression.. 3. 2001
- Enhanced therapeutic effect of HSV-tk+GCV gene therapy and ionizing radiation for prostate cancer.. 3. 2001
- In vivo surgical resection plus adjuvant gene therapy in the treatment of mammary and prostate cancer.. 3. 2001
- Host responses and persistence of vector genome following intrabronchial administration of an E1(-)E3(-) adenovirus gene transfer vector to normal individuals.. 3. 2001
- Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene.. 3. 2001
- DNA/dendrimer complexes mediate gene transfer into murine cardiac transplants ex vivo.. 2. 2000
- Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo.. 2. 2000
- Downregulation of CXCR4 gene expression in primary human endothelial cells following infection with E1(-)E4(+) adenovirus gene transfer vectors.. 2. 2000
- Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.. 1. 2000
- Free cholesterol enhances adenoviral vector gene transfer and expression in CAR-deficient cells.. 1. 2000
- Fluorescence methods reveal intracellular trafficking of gene transfer vectors: the light toward the end of the tunnel.. 1. 2000
- Treatment of chronic lymphocytic leukemia with genetically targeted autologous T cells: case report of an unforeseen adverse event in a phase I clinical trial. 2010
- Genome editing technologies: defining a path to clinic. 2015
- T-cell immunotherapy: looking forward. 2014
- CARs on track in the clinic. 2011
- AAV and hepatitis: Cause or coincidence? 2022
- Liver gene therapy and hepatocellular carcinoma: A complex web.. 29. 2021
- Modeling Unique Patients in Humanized Mice: Toward a Curative Strategy for HIV.. 26. 2018
- A New Induction to the Gene and Cell Therapy Hall Of Fame: Genome Editing.. 24. 2016
- The challenge of using gene- or cell-based therapies to treat lung disease.. 20. 2012
- The need for genetically engineering therapeutic pluripotent stem cells.. 18. 2010
- Translating stem cell therapy to the clinic: déjà vu all over again.. 17. 2009
- A "vector drain" in US gene therapy development?. 16. 2008
- Immune Responses to Viral Gene Therapy Vectors. 2020
- Chimeric Antigen Receptors: A Cell and Gene Therapy Perspective. 2017
- ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities. 2014
- Supplying clotting factors from hematopoietic stem cell-derived erythroid and megakaryocytic lineage cells. 2009
- Human embryonic stem cells and gene therapy. 2007
- The genetic engineering of hematopoietic stem cells: the rise of lentiviral vectors, the conundrum of the ltr, and the promise of lineage-restricted vectors. 2007
- American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells. 2003
- Sturm und drang over suicidal lymphocytes. 2002
- Evaluating the State of the Science for Adeno-Associated Virus (AAV) Integration:An Integrated Perspective. 2022
- Multipurposing CARs: Same engine, different vehicles. 2022
- Molecular therapies for colorectal cancer metastatic to the liver. 2002