Biophysical journal

publication venue for

Introduction to Biophysics Week: What is Biophysics? 2017
Molecular Simulations and NMR Reveal How Lipid Fluctuations Affect Membrane Mechanics. 2022
Conformational transitions in BTG1 antiproliferative protein and their modulation by disease mutants. 2022
Ca²⁺-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide.. 120. 2021
Mycobacterial STAND adenylyl cyclases: The HTH domain binds DNA to form biocrystallized nucleoids.. 120. 2020
Molecular Mechanism for Gramicidin Dimerization and Dissociation in Bilayers of Different Thickness.. 117. 2019
Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles.. 116. 2019
A New Computational Method for Membrane Compressibility: Bilayer Mechanical Thickness Revisited.. 116. 2019
Light-Activated Dynamic Clamp Using iPSC-Derived Cardiomyocytes.. 115. 2018
Accurate In Silico Modeling of Asymmetric Bilayers Based on Biophysical Principles.. 115. 2018
Fluorinated Alcohols' Effects on Lipid Bilayer Properties.. 115. 2018
A Protofilament-Protofilament Interface in the Structure of Mouse α-Synuclein Fibrils.. 114. 2018
Thermodynamic Coupling Function Analysis of Allosteric Mechanisms in the Human Dopamine Transporter.. 114. 2017
Cholesterol Promotes Protein Binding by Affecting Membrane Electrostatics and Solvation Properties.. 113. 2017
Lysenin Toxin Membrane Insertion Is pH-Dependent but Independent of Neighboring Lysenins.. 113. 2017
Exchange of Gramicidin between Lipid Bilayers: Implications for the Mechanism of Channel Formation.. 113. 2017
Influence of Protein Scaffold on Side-Chain Transfer Free Energies.. 113. 2017
Gramicidin A Channel Formation Induces Local Lipid Redistribution I: Experiment and Simulation.. 112. 2017
Gramicidin A Channel Formation Induces Local Lipid Redistribution II: A 3D Continuum Elastic Model.. 112. 2017
Glycan Determinants of Heparin-Tau Interaction.. 112. 2017
The nhTMEM16 Scramblase Is Also a Nonselective Ion Channel.. 111. 2016
Illuminating Myocyte-Fibroblast Homotypic and Heterotypic Gap Junction Dynamics Using Dynamic Clamp.. 111. 2016
Effect of Statins on the Nanomechanical Properties of Supported Lipid Bilayers.. 111. 2016
Multiscale Simulations Reveal Key Aspects of the Proton Transport Mechanism in the ClC-ec1 Antiporter.. 110. 2016
Direct Measurement of the Structure of Reconstituted High-Density Lipoproteins by Cryo-EM.. 110. 2015
Predicting first traversal times for virions and nanoparticles in mucus with slowed diffusion.. 109. 2015
Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis.. 108. 2015
Structural, mechanical, and dynamical variability of the actin cortex in living cells.. 108. 2015
Synaptic activity regulates the abundance and binding of complexin.. 108. 2015
Quantifying the entropy of binding for water molecules in protein cavities by computing correlations.. 108. 2015
Tau binds to lipid membrane surfaces via short amphipathic helices located in its microtubule-binding repeats.. 107. 2014
Light harvesting by lamellar chromatophores in Rhodospirillum photometricum.. 106. 2014
Voltage and calcium dynamics both underlie cellular alternans in cardiac myocytes.. 106. 2014
Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.. 106. 2014
Ion-induced defect permeation of lipid membranes.. 106. 2014
Active-site structure of the thermophilic Foc-subunit ring in membranes elucidated by solid-state NMR.. 106. 2014
Microvascular endothelial cells migrate upstream and align against the shear stress field created by impinging flow.. 106. 2014
Optoporation and genetic manipulation of cells using femtosecond laser pulses.. 105. 2013
Small-molecule photostabilizing agents are modifiers of lipid bilayer properties.. 104. 2013
Ion-controlled conformational dynamics in the outward-open transition from an occluded state of LeuT.. 103. 2012
Multi-ion distributions in the cytoplasmic domain of inward rectifier potassium channels.. 103. 2012
Residues at the outer mouth of Kir1.1 determine K-dependent gating.. 102. 2012
Influence of hydrophobic mismatch on structures and dynamics of gramicidin a and lipid bilayers.. 102. 2012
Qualitative network modeling of the Myc-p53 control system of cell proliferation and differentiation.. 101. 2011
Quantitative modeling of membrane deformations by multihelical membrane proteins: application to G-protein coupled receptors.. 101. 2011
Alcohol's effects on lipid bilayer properties.. 101. 2011
Modulation of Kir1.1 inactivation by extracellular Ca and Mg.. 100. 2011
Conformational rearrangements to the intracellular open states of the LeuT and ApcT transporters are modulated by common mechanisms.. 99. 2010
Counting bungarotoxin binding sites of nicotinic acetylcholine receptors in mammalian cells with high signal/noise ratios.. 99. 2010
Anthropomorphizing the mouse cardiac action potential via a novel dynamic clamp method.. 97. 2009
Energy transfer in light-adapted photosynthetic membranes: from active to saturated photosynthesis.. 97. 2009
Modeling membrane deformations and lipid demixing upon protein-membrane interaction: the BAR dimer adsorption.. 97. 2009
Contact-mode high-resolution high-speed atomic force microscopy movies of the purple membrane.. 97. 2009
An intersubunit salt bridge near the selectivity filter stabilizes the active state of Kir1.1.. 97. 2009
Structural information, resolution, and noise in high-resolution atomic force microscopy topographs.. 96. 2009
Mitigating unwanted photophysical processes for improved single-molecule fluorescence imaging.. 96. 2009
Cardiac myocyte excitation by ultrashort high-field pulses.. 96. 2009
Protein-protein interaction investigated by steered molecular dynamics: the TCR-pMHC complex.. 95. 2008
Mutations affecting the oligomerization interface of G-protein-coupled receptors revealed by a novel de novo protein design framework.. 94. 2008
Protein diffusion on charged membranes: a dynamic mean-field model describes time evolution and lipid reorganization.. 94. 2007
Rows of ATP synthase dimers in native mitochondrial inner membranes.. 93. 2007
Action potential duration dispersion and alternans in simulated heterogeneous cardiac tissue with a structural barrier.. 92. 2006
Lateral organization in lipid-cholesterol mixed bilayers.. 92. 2006
Dynamics and diffusion in photosynthetic membranes from rhodospirillum photometricum.. 91. 2006
Localization of the pH gate in Kir1.1 channels.. 91. 2006
The DNA binding activity of p53 displays reaction-diffusion kinetics.. 91. 2006
Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy.. 90. 2006
Role of conserved glycines in pH gating of Kir1.1 (ROMK).. 90. 2006
Ion permeation through a narrow channel: using gramicidin to ascertain all-atom molecular dynamics potential of mean force methodology and biomolecular force fields.. 90. 2006
Subcellular in vivo 1H MR spectroscopy of Xenopus laevis oocytes.. 90. 2005
Detection of forces and displacements along the axial direction in an optical trap.. 90. 2005
Action potential morphology influences intracellular calcium handling stability and the occurrence of alternans.. 90. 2005
pH dependence of amide chemical shifts in natively disordered polypeptides detects medium-range interactions with ionizable residues.. 89. 2005
Structural locus of the pH gate in the Kir1.1 inward rectifier channel.. 88. 2005
Liganded hemoglobin structural perturbations by the allosteric effector L35.. 88. 2004
A single-molecule technique to study sequence-dependent transcription pausing.. 87. 2004
Potassium-dependent slow inactivation of Kir1.1 (ROMK) channels.. 86. 2004
Liquid-liquid phase separation in hemoglobins: distinct aggregation mechanisms of the beta6 mutants.. 86. 2004
Energetic and structural considerations for the mechanism of protein sliding along DNA in the nonspecific BamHI-DNA complex.. 84. 2003
Role of hyperpolarization-activated currents for the intrinsic dynamics of isolated retinal neurons.. 84. 2003
Cholesterol-induced protein sorting: an analysis of energetic feasibility.. 84. 2003
MC-PHS: a Monte Carlo implementation of the primary hydration shell for protein folding and design.. 84. 2003
Permeant cations and blockers modulate pH gating of ROMK channels.. 84. 2003
Probing protein-DNA interactions by unzipping a single DNA double helix.. 83. 2002
Regulation of ROMK by extracellular cations.. 80. 2001
Inclusion-induced bilayer deformations: effects of monolayer equilibrium curvature.. 79. 2000
Molecular dynamics simulations predict a tilted orientation for the helical region of dynorphin A(1-17) in dimyristoylphosphatidylcholine bilayers.. 79. 2000
The use of pHluorins for optical measurements of presynaptic activity.. 79. 2000
Binding mechanisms of TATA box-binding proteins: DNA kinking is stabilized by specific hydrogen bonds.. 78. 2000
Stretching of single collapsed DNA molecules.. 78. 2000
Ca2+-dependent gating mechanisms for dSlo, a large-conductance Ca2+-activated K+ (BK) channel.. 76. 1999
The role of a conserved proline residue in mediating conformational changes associated with voltage gating of Cx32 gap junctions.. 76. 1999
Structural determinants of gating in inward-rectifier K+ channels.. 76. 1999
Electrostatically balanced subnanometer imaging of biological specimens by atomic force microscope.. 76. 1999
Spring constants for channel-induced lipid bilayer deformations. Estimates using gramicidin channels.. 76. 1999
Estimating the persistence length of a worm-like chain molecule from force-extension measurements.. 76. 1999
Interaction of alpha-tocopherol with model human high-density lipoproteins.. 75. 1998
Selective binding of the TATA box-binding protein to the TATA box-containing promoter: analysis of structural and energetic factors.. 75. 1998
Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog.. 75. 1998
A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif.. 75. 1998
Progressive DNA bending is made possible by gradual changes in the torsion angle of the glycosyl bond.. 74. 1998
Energetics of inclusion-induced bilayer deformations.. 74. 1998
Structure and dynamics of calmodulin in solution.. 74. 1998
Asymmetrical distribution of Ca-activated Cl channels in Xenopus oocytes.. 74. 1998
Surface properties of native human plasma lipoproteins and lipoprotein models.. 74. 1998
Gramicidin channel kinetics under tension.. 74. 1998
Gramicidin channels in phospholipid bilayers with unsaturated acyl chains.. 73. 1997
Does TATA matter? A structural exploration of the selectivity determinants in its complexes with TATA box-binding protein.. 73. 1997
Ionization, partitioning, and dynamics of tryptophan octyl ester: implications for membrane-bound tryptophan residues.. 73. 1997
Spontaneous transfer of monoacyl amphiphiles between lipid and protein surfaces.. 72. 1997
Stretching DNA with optical tweezers.. 72. 1997
13C NMR of Nephila clavipes major ampullate silk gland.. 71. 1996
Photophysics of a neurotransmitter: ionization and spectroscopic properties of serotonin.. 71. 1996
Multiple residues specify external tetraethylammonium blockade in voltage-gated potassium channels.. 69. 1995
Environments of the four tryptophans in the extracellular domain of human tissue factor: comparison of results from absorption and fluorescence difference spectra of tryptophan replacement mutants with the crystal structure of the wild-type protein.. 69. 1995
Functional role of a conserved aspartate in the external mouth of voltage-gated potassium channels.. 68. 1995
Intracellular calcium levels correlate with speed and persistent forward motion in migrating neutrophils.. 68. 1995
Asymmetric gramicidin channels: heterodimeric channels with a single F6Val1 residue.. 66. 1994
Evidence of an associative intermediate on the myoglobin refolding pathway.. 65. 1993
A dipolar amino acid substitution induces voltage-dependent transitions between two stable conductance states in gramicidin channels.. 62. 1992
Amino acid substitutions and ion channel function. Model-dependent conclusions.. 62. 1992
Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains.. 62. 1992
Formation of non-beta 6.3-helical gramicidin channels between sequence-substituted gramicidin analogues.. 62. 1992
The role of Pro/Hyp-kinks in determining the transmembrane helix length and gating mechanism of a [Leu]zervamicin channel.. 62. 1992
On the supramolecular organization of gramicidin channels. The elementary conducting unit is a dimer.. 61. 1992
Gramicidins A, B, and C form structurally equivalent ion channels.. 58. 1990
Gramicidin single-channel properties show no solvent-history dependence.. 57. 1990
Interactions of amiloride and small monovalent cations with the epithelial sodium channel. Inferences about the nature of the channel pore.. 55. 1989
Thermodynamic parameters for the binding of divalent cations to gramicidin A incorporated into a lipid environment by Tl-205 nuclear magnetic resonance.. 55. 1989
TI-205 nuclear magnetic resonance determination of the thermodynamic parameters for the binding of monovalent cations to gramicidins A and C.. 54. 1988
23Na-nuclear magnetic resonance investigation of gramicidin-induced ion transport through membranes under equilibrium conditions.. 53. 1988
On the conductance heterogeneity in membrane channels formed by gramicidin A. A cooperative study.. 51. 1987
Equilibrium binding constants for the group I metal cations with gramicidin-A determined by competition studies and T1+-205 nuclear magnetic resonance spectroscopy.. 50. 1986
Single-channel studies on linear gramicidins with altered amino acid side chains. Effects of altering the polarity of the side chain at position 1 in gramicidin A.. 49. 1986
Equilibrium binding constants for Tl+ with gramicidins A, B and C in a lysophosphatidylcholine environment determined by 205Tl nuclear magnetic resonance spectroscopy.. 49. 1986
Structural information from functional measurements: single-channel studies on gramicidin analogues.. 49. 1986
Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11.. 45. 1984
Nonequilibrium thermodynamic model of the rat proximal tubule epithelium.. 44. 1983
Ion movement through gramicidin A channels. Interfacial polarization effects on single-channel current measurements.. 41. 1983
Ion movement through gramicidin A channels. Single-channel measurements at very high potentials.. 41. 1983
Ion movement through gramicidin A channels. Studies on the diffusion-controlled association step.. 41. 1983
Lipoprotein Lipase Interaction with Synthetic N-Dansyl Fragments of Apolipoprotein C-II.. 37. 1982
Mechanism of association of human plasma apolipoproteins with dimyristoylphosphatidylcholine: effect of lipid clusters on reaction rates.. 37. 1982
Thermodynamics of lipid-protein association in human plasma lipoproteins.. 37. 1982
Coupled water transport in standing gradient models of the lateral intercellular space.. 35. 1981
Structural dynamics of liganded myoglobin.. 32. 1980
A method of nonlinear analysis in the frequency domain.. 29. 1980
Electrolyte transport across a simple epithelium. Steady-state and transient analysis.. 27. 1979
On the adsorption of phloretin onto a black lipid membrane.. 25. 1979
Electrostatic interactions among hydrophobic ions in lipid bilayer membranes.. 21. 1978
Potential energy barriers to ion transport within lipid bilayers. Studies with tetraphenylborate.. 15. 1975
A comment on nonlinear analysis.. 35. 1981
External K activation of Kir1.1 depends on the pH gate. 2007
Models for gramicidin channels. 1992
Dimer versus tetramer. 1992
Introduction to Biophysics Week: What is Biophysics?. 110. 2016
Not just an oil slick: how the energetics of protein-membrane interactions impacts the function and organization of transmembrane proteins. 2014
Sequencing and the single channel. 1999

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