Estimating the persistence length of a worm-like chain molecule from force-extension measurements. Academic Article uri icon

Overview

abstract

  • We describe a simple computation of the worm-like chain model and obtain the corresponding force-versus-extension curve. We propose an improvement to the Marko and Siggia interpolation formula of Bustamante et al (Science 1994, 265:1599-1600) that is useful for fitting experimental data. We apply it to the experimental elasticity curve of single DNA molecules. Finally, we present a tool to study the agreement between the worm-like chain model and experiments.

publication date

  • January 1, 1999

Research

keywords

  • DNA

Identity

PubMed Central ID

  • PMC1302529

Scopus Document Identifier

  • 0032937079

PubMed ID

  • 9876152

Additional Document Info

volume

  • 76

issue

  • 1 Pt 1