Monoclonal antibody-based therapy of neuroblastoma. Review uri icon

Overview

abstract

  • The curative potential of mAbs in the treatment of patients with metastatic neuroblastoma is increasingly evident. The idiotype network appears to represent one component of a complex mechanism for success with mAb-based immunotherapy. Ongoing strategies to modify or reconstruct mAbs, to engage them with cytokines, or to unite them with T cells open new avenues for harnessing the unique forces of the immune system against some of the most deadly pediatric cancers.

publication date

  • October 1, 2001

Research

keywords

  • Antibodies, Anti-Idiotypic
  • Antibodies, Monoclonal
  • Immunotherapy, Active
  • Neuroblastoma

Identity

Scopus Document Identifier

  • 0035672513

PubMed ID

  • 11765377

Additional Document Info

volume

  • 15

issue

  • 5