Kushner, Brian Harris

Publications

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selected publications

Long-term Pulmonary Outcomes in Pediatric Survivors of High-risk Neuroblastoma. Journal of pediatric hematology/oncology. 2017 Academic Article GET IT
Times cited: 10
A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors. PloS one. 2017 Academic Article GET IT
Times cited: 33
A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma. International journal of cancer. 2016 Academic Article GET IT
Times cited: 41
Local Control With 21-Gy Radiation Therapy for High-Risk Neuroblastoma. International journal of radiation oncology, biology, physics. 2016 Academic Article GET IT
Times cited: 42
Lack of survival advantage with autologous stem-cell transplantation in high-risk neuroblastoma consolidated by anti-GD2 immunotherapy and isotretinoin. Oncotarget. 2016 Academic Article GET IT
Times cited: 54
Arsenic Trioxide as a Radiation Sensitizer for 131I-Metaiodobenzylguanidine Therapy: Results of a Phase II Study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2016 Academic Article GET IT
Times cited: 16
Salvage rates after progression of high-risk neuroblastoma with a soft tissue mass. Journal of pediatric surgery. 2015 Academic Article GET IT
Times cited: 7
Prolonged progression-free survival after consolidating second or later remissions of neuroblastoma with Anti-G_D2 immunotherapy and isotretinoin: a prospective Phase II study. Oncoimmunology. 2015 Academic Article GET IT
Myeloablative chemotherapy with autologous stem cell transplant for desmoplastic small round cell tumor. Sarcoma. 2015 Academic Article GET IT
Times cited: 20
When overall survival fails to confirm event-free survival, should the latter be used to set the standard of care?. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2014 Article GET IT
Times cited: 6
Key role for myeloid cells: phase II results of anti-G(D2) antibody 3F8 plus granulocyte-macrophage colony-stimulating factor for chemoresistant osteomedullary neuroblastoma. International journal of cancer. 2014 Academic Article GET IT
Times cited: 85
Striking dichotomy in outcome of MYCN-amplified neuroblastoma in the contemporary era. Cancer. 2014 Academic Article GET IT
Times cited: 36
Posterior reversible encephalopathy syndrome in neuroblastoma patients receiving anti-GD2 3F8 monoclonal antibody. Cancer. 2013 Academic Article GET IT
Times cited: 26
Anti-GD2 antibody 3F8 and barley-derived (1 → 3),(1 → 4)-β-D-glucan: A Phase I study in patients with chemoresistant neuroblastoma. Oncoimmunology. 2013 Academic Article GET IT
Reply to L. Moreno et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2013 Article GET IT
Times cited: 1
5-day/5-drug myeloablative outpatient regimen for resistant neuroblastoma. Bone marrow transplantation. 2012 Academic Article GET IT
Times cited: 3
Reduced toxicity with intensity modulated radiation therapy (IMRT) for desmoplastic small round cell tumor (DSRCT): an update on the whole abdominopelvic radiation therapy (WAP-RT) experience. International journal of radiation oncology, biology, physics. 2012 Academic Article GET IT
Times cited: 40
Murine anti-GD2 monoclonal antibody 3F8 combined with granulocyte-macrophage colony-stimulating factor and 13-cis-retinoic acid in high-risk patients with stage 4 neuroblastoma in first remission. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2012 Academic Article GET IT
Times cited: 222
Plerixafor plus granulocyte-colony stimulating factor for autologous hematopoietic stem cell mobilization in patients with metastatic neuroblastoma. Pediatric blood & cancer. 2011 Academic Article GET IT
Times cited: 23
High-dose carboplatin-irinotecan-temozolomide: treatment option for neuroblastoma resistant to topotecan. Pediatric blood & cancer. 2011 Academic Article GET IT
Times cited: 22
Successful multifold dose escalation of anti-GD2 monoclonal antibody 3F8 in patients with neuroblastoma: a phase I study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2011 Academic Article GET IT
Times cited: 51
High-dose cyclophosphamide-irinotecan-vincristine for primary refractory neuroblastoma. European journal of cancer. 2010 Academic Article GET IT
Times cited: 13
Preliminary results of a phase I trial of prophylactic ethanol-lock administration to prevent mediport catheter-related bloodstream infections. Journal of pediatric surgery. 2010 Academic Article GET IT
Times cited: 38
Hypothyroidism after 131I-monoclonal antibody treatment of neuroblastoma. Pediatric blood & cancer. 2010 Academic Article GET IT
Times cited: 5
Differential impact of high-dose cyclophosphamide, topotecan, and vincristine in clinical subsets of patients with chemoresistant neuroblastoma. Cancer. 2010 Academic Article GET IT
Times cited: 30
Whole neuraxis irradiation to address central nervous system relapse in high-risk neuroblastoma. International journal of radiation oncology, biology, physics. 2010 Academic Article GET IT
Times cited: 8
Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma. Journal of neuro-oncology. 2009 Academic Article GET IT
Times cited: 203
Reduced risk of secondary leukemia with fewer cycles of dose-intensive induction chemotherapy in patients with neuroblastoma. Pediatric blood & cancer. 2009 Academic Article GET IT
Times cited: 38
Hyperfractionated low-dose (21 Gy) radiotherapy for cranial skeletal metastases in patients with high-risk neuroblastoma. International journal of radiation oncology, biology, physics. 2009 Academic Article GET IT
Times cited: 8
Specific gene expression profiles and chromosomal abnormalities are associated with infant disseminated neuroblastoma. BMC cancer. 2009 Academic Article GET IT
Times cited: 26
Sensitivity of surveillance studies for detecting asymptomatic and unsuspected relapse of high-risk neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2009 Academic Article GET IT
Times cited: 70
Management and outcome of stage 3 neuroblastoma. European journal of cancer. 2008 Academic Article GET IT
Times cited: 38
Brain-sparing radiotherapy for neuroblastoma skull metastases. Pediatric blood & cancer. 2008 Academic Article GET IT
Times cited: 8
Transient sialoadenitis: a complication of 131I-metaiodobenzylguanidine therapy. Pediatric blood & cancer. 2008 Academic Article GET IT
Times cited: 30
Neuroblastoma--linking a common allele to a rare disease. The New England journal of medicine. 2008 Editorial Article GET IT
Times cited: 4
High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy. Pediatric blood & cancer. 2007 Academic Article GET IT
Times cited: 20
Irinotecan plus temozolomide for relapsed or refractory neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2006 Academic Article GET IT
Times cited: 96
Ototoxicity from high-dose use of platinum compounds in patients with neuroblastoma. Cancer. 2006 Academic Article GET IT
Times cited: 100
FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2006 Academic Article GET IT
Times cited: 86
What factors predict a favorable outcome in young children with disseminated neuroblastoma?. Nature clinical practice. Oncology. 2006 Academic Article GET IT
Topotecan, thiotepa, and carboplatin for neuroblastoma: failure to prevent relapse in the central nervous system. Bone marrow transplantation. 2006 Academic Article GET IT
Times cited: 23
Long-term complications in survivors of advanced stage neuroblastoma. Pediatric blood & cancer. 2005 Academic Article GET IT
Times cited: 124
Reduction from seven to five cycles of intensive induction chemotherapy in children with high-risk neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2004 Academic Article GET IT
Times cited: 84
Neuroblastoma: a disease requiring a multitude of imaging studies. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2004 Review GET IT
Times cited: 192
The impact of gross total resection on local control and survival in high-risk neuroblastoma. Journal of pediatric surgery. 2004 Academic Article GET IT
Times cited: 134
Camptothecin analogs (irinotecan or topotecan) plus high-dose cyclophosphamide as preparative regimens for antibody-based immunotherapy in resistant neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2004 Academic Article GET IT
Times cited: 37
Neuroblastoma in adolescents and adults: the Memorial Sloan-Kettering experience. Medical and pediatric oncology. 2003 Academic Article GET IT
Times cited: 62
Early molecular response of marrow disease to biologic therapy is highly prognostic in neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2003 Academic Article GET IT
Times cited: 41
Long-term event-free survival after intensive chemotherapy for Ewing's family of tumors in children and young adults. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2003 Academic Article GET IT
Times cited: 132
Oral topotecan for refractory and relapsed neuroblastoma: a retrospective analysis. Journal of pediatric hematology/oncology. 2003 Academic Article GET IT
Times cited: 24
Curability of recurrent disseminated disease after surgery alone for local-regional neuroblastoma using intensive chemotherapy and anti-G(D2) immunotherapy. Journal of pediatric hematology/oncology. 2003 Academic Article GET IT
Times cited: 19
Impact of metaiodobenzylguanidine scintigraphy on assessing response of high-risk neuroblastoma to dose-intensive induction chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2003 Academic Article GET IT
Times cited: 49
Quantitation of GD2 synthase mRNA by real-time reverse transcriptase polymerase chain reaction: clinical utility in evaluating adjuvant therapy in neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2003 Academic Article GET IT
Times cited: 45
Should we replace bone scintigraphy plus CT with MR imaging for staging of neuroblastoma?. Radiology. 2003 Article GET IT
Times cited: 4
Chronic neuroblastoma. Cancer. 2002 Academic Article GET IT
Times cited: 23
Whole abdominopelvic radiotherapy for desmoplastic small round-cell tumor. International journal of radiation oncology, biology, physics. 2002 Academic Article GET IT
Times cited: 65
Quantitation of GD2 synthase mRNA by real-time reverse transcription-polymerase chain reaction: utility in bone marrow purging of neuroblastoma by anti-GD2 antibody 3F8. Cancer. 2002 Academic Article GET IT
Times cited: 19
Phase II trial of the anti-G(D2) monoclonal antibody 3F8 and granulocyte-macrophage colony-stimulating factor for neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2001 Academic Article GET IT
Times cited: 161
Monoclonal antibody-based therapy of neuroblastoma. Hematology/oncology clinics of North America. 2001 Information Resource GET IT
Times cited: 32
Topotecan combined with myeloablative doses of thiotepa and carboplatin for neuroblastoma, brain tumors, and other poor-risk solid tumors in children and young adults. Bone marrow transplantation. 2001 Academic Article GET IT
Times cited: 50
Extending positron emission tomography scan utility to high-risk neuroblastoma: fluorine-18 fluorodeoxyglucose positron emission tomography as sole imaging modality in follow-up of patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2001 Academic Article GET IT
Times cited: 138
Hyperfractionated low-dose radiotherapy for high-risk neuroblastoma after intensive chemotherapy and surgery. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2001 Academic Article GET IT
Times cited: 99
How effective is dose-intensive/myeloablative therapy against Ewing's sarcoma/primitive neuroectodermal tumor metastatic to bone or bone marrow? The Memorial Sloan-Kettering experience and a literature review. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2001 Information Resource GET IT
Times cited: 108
Granulocyte-colony stimulating factor and multiple cycles of strongly myelosuppressive alkylator-based combination chemotherapy in children with neuroblastoma. Cancer. 2000 Academic Article GET IT
Times cited: 17
Successful treatment of metastatic retinoblastoma. Cancer. 2000 Academic Article GET IT
Times cited: 80
Pilot study of topotecan and high-dose cyclophosphamide for resistant pediatric solid tumors. Medical and pediatric oncology. 2000 Academic Article GET IT
Times cited: 61
Local control with multimodality therapy for stage 4 neuroblastoma. International journal of radiation oncology, biology, physics. 2000 Academic Article GET IT
Times cited: 63
Clinically critical impact of molecular genetic studies in pediatric solid tumors. Medical and pediatric oncology. 1999 Academic Article GET IT
Times cited: 31
Oral etoposide for refractory and relapsed neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1999 Academic Article GET IT
Effect of low-dose radiation therapy when combined with surgical resection for Ewing sarcoma. Medical and pediatric oncology. 1999 Academic Article GET IT
Times cited: 28
Detection of neuroblastoma in bone marrow by immunocytology: is a single marrow aspirate adequate?. Medical and pediatric oncology. 1999 Academic Article GET IT
Times cited: 12
Neuroblastoma and treatment-related myelodysplasia/leukemia: the Memorial Sloan-Kettering experience and a literature review. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1998 Information Resource GET IT
Anti-G(D2) antibody treatment of minimal residual stage 4 neuroblastoma diagnosed at more than 1 year of age. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1998 Academic Article GET IT
Clinical, pathologic, and molecular spectrum of tumors associated with t(11;22)(p13;q12): desmoplastic small round-cell tumor and its variants. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1998 Academic Article GET IT
Times cited: 311
Disialoganglioside G(D2) loss following monoclonal antibody therapy is rare in neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 1998 Academic Article GET IT
Times cited: 46
High risk of leukemia after short-term dose-intensive chemotherapy in young patients with solid tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1998 Academic Article GET IT
Desmoplastic small round cell tumors: prognostic indicators and results of surgical management. Annals of surgical oncology. 1998 Academic Article GET IT
Times cited: 81
3F8 monoclonal antibody treatment of patients with stage 4 neuroblastoma: a phase II study. International journal of oncology. 1998 Academic Article GET IT
Times cited: 82
Detection of metastatic neuroblastoma in bone marrow: when is routine marrow histology insensitive?. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1997 Academic Article GET IT
International neuroblastoma staging system stage 1 neuroblastoma: a prospective study and literature review. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1996 Information Resource GET IT
Allelic loss of chromosome 1p in neuroblastoma. The New England journal of medicine. 1996 Article GET IT
Desmoplastic small round-cell tumor: prolonged progression-free survival with aggressive multimodality therapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1996 Academic Article GET IT
Survival from locally invasive or widespread neuroblastoma without cytotoxic therapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1996 Academic Article GET IT
Very-high-dose short-term chemotherapy for poor-risk peripheral primitive neuroectodermal tumors, including Ewing's sarcoma, in children and young adults. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1995 Academic Article GET IT
Times cited: 137
Highly effective induction therapy for stage 4 neuroblastoma in children over 1 year of age. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1994 Academic Article GET IT
Times cited: 149
Stage 4 neuroblastoma diagnosed at more than 1 year of age: gross total resection and clinical outcome. Journal of pediatric surgery. 1994 Academic Article GET IT
Times cited: 72
Antibody response to murine anti-GD2 monoclonal antibodies: correlation with patient survival. Cancer research. 1994 Academic Article GET IT
Times cited: 71
3F8 monoclonal antibody treatment of patients with stage IV neuroblastoma: a phase II study. Progress in clinical and biological research. 1994 Academic Article GET IT
Times cited: 14
Rethinking management of localized neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1993 Article GET IT
Times cited: 3
Clinically effective monoclonal antibody 3F8 mediates nonoxidative lysis of human neuroectodermal tumor cells by polymorphonuclear leukocytes. Cancer research. 1991 Academic Article GET IT
Times cited: 40
High-dose melphalan with 6-hydroxydopamine-purged autologous bone marrow transplantation for poor-risk neuroblastoma. Cancer. 1991 Academic Article GET IT
Times cited: 18
Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 1991 Academic Article GET IT
Times cited: 77
Extracranial primitive neuroectodermal tumors. The Memorial Sloan-Kettering Cancer Center experience. Cancer. 1991 Academic Article GET IT
Times cited: 193
Cyclophosphamide and the heart. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1991 Article GET IT
Times cited: 4
Myeloablative combination chemotherapy without total body irradiation for neuroblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1991 Academic Article GET IT
Times cited: 84
131I-3F8: clinical validation of imaging studies and therapeutic applications. Progress in clinical and biological research. 1991 Academic Article GET IT
Times cited: 6
Monoclonal antibody 3F8 can effect durable remissions in neuroblastoma patients refractory to chemotherapy: a phase II trial. Progress in clinical and biological research. 1991 Academic Article GET IT
Times cited: 24
Stage IV neuroblastoma more than 1 year of age at diagnosis: major response to chemotherapy and survival durations correlated strongly with dose intensity. Progress in clinical and biological research. 1991 Academic Article GET IT
Times cited: 9
Dose-intensive use of cyclophosphamide in ablation of neuroblastoma. Cancer. 1990 Academic Article GET IT
Times cited: 51
Autografting with bone marrow exposed to multiple courses of very high dose cyclophosphamide in vivo and to 4-hydroperoxycyclophosphamide in vitro. Medical and pediatric oncology. 1990 Academic Article GET IT
Times cited: 8
GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma. Blood. 1989 Academic Article GET IT
Times cited: 151
Second malignancies after childhood Hodgkin's disease. The Memorial Sloan-Kettering Cancer Center experience. Cancer. 1988 Review GET IT
Times cited: 57
Neuroblastoma. Pediatric annals. 1988 Information Resource GET IT
Times cited: 12
Anti-tumor efficacy of interleukin-2-activated killer cells in human neuroblastoma ex vivo. Experimental cell biology. 1988 Academic Article GET IT
Times cited: 2
Coordinated use of sequentially escalated cyclophosphamide and cell-cycle-specific chemotherapy (N4SE protocol) for advanced neuroblastoma: experience with 100 patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 1987 Academic Article GET IT
Times cited: 44
Juvenile chronic myeloid leukemia: therapeutic insights. Leukemia. 1987 Academic Article GET IT
Times cited: 7
Myeloablation with diaziquone: in vitro assessment. Blood. 1987 Academic Article GET IT
Times cited: 3
Preclinical assessment of purging with VP-16-213: key role for long-term marrow cultures. Blood. 1987 Academic Article GET IT
Times cited: 15
Metastatic neuroblastoma after 52 years of apparent dormancy. The New England journal of medicine. 1986 Article GET IT
Times cited: 2
Familial neuroblastoma. Case reports, literature review, and etiologic considerations. 1986 GET IT
Times cited: 121
Metastatic neuroblastoma and testicular involvement. Cancer. 1985 Academic Article GET IT
Times cited: 29
Monozygotic siblings discordant for neuroblastoma: etiologic implications. 1985 GET IT
Times cited: 20
Synchronous neuroblastoma and von Recklinghausen's disease: a review of the literature. 1985 GET IT
Times cited: 49

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Background

education and training

M.D., The Johns Hopkins University School of Medicine 1976
A.B., Harvard University 1972

Contact

full name

Brian Harris Kushner

VIVO Weill Cornell Medical College

Brian Harris Kushner Professor of Clinical Pediatrics

Publications

selected publications

Background

education and training

Contact

full name