Alpha-mediated vasoconstriction: transmembrane signalling and receptor reclassification.

Overview

Apparent differences in the usage of different calcium pools for the processes of excitation-contraction provides support for further sub-classification of the alpha-adrenoceptors in blood vessels. Presently we have addressed this question by assessing the routes of calcium utilization and the involvement of G-proteins in mediating vasoconstriction in situ.