HLA-A2-restricted CD8+-cytotoxic-T-cell responses to novel epitopes in Mycobacterium tuberculosis superoxide dismutase, alanine dehydrogenase, and glutamine synthetase. Academic Article uri icon

Overview

abstract

  • Major histocompatibility complex class I-restricted CD8(+) cytotoxic T lymphocytes (CTL) are implicated in protective Th1 immunity to Mycobacterium tuberculosis infection. We report the identification of three novel HLA-A*0201-restricted CTL epitopes within mycobacterial superoxide dismutase (SodA), L-alanine dehydrogenase (AlaDH), and L-glutamine synthetase (GlnS) proteins.

publication date

  • April 1, 2004

Research

keywords

  • Amino Acid Oxidoreductases
  • Epitopes, T-Lymphocyte
  • Glutamate-Ammonia Ligase
  • HLA-A2 Antigen
  • Mycobacterium tuberculosis
  • Superoxide Dismutase
  • T-Lymphocytes, Cytotoxic

Identity

PubMed Central ID

  • PMC375155

Scopus Document Identifier

  • 1842588003

PubMed ID

  • 15039371

Additional Document Info

volume

  • 72

issue

  • 4