Infection and immunity

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Chronological development of cellular immunity in human toxoplasmosis. 1981
Transiently boosting Vγ9+Vδ2+ γδ T cells early in Mtb coinfection of SIV-infected juvenile macaques does not improve Mtb host resistance. 2024
Dectin-1/CARD9 induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-Aspergillus activity in the lung. 2023
Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques.. 91. 2023
Butyrate Differentiates Permissiveness to Clostridioides difficile Infection and Influences Growth of Diverse C. difficile Isolates.. 91. 2023
Efficient 5-OP-RU-Induced Enrichment of Mucosa-Associated Invariant T Cells in the Murine Lung Does Not Enhance Control of Aerosol Mycobacterium tuberculosis Infection.. 89. 2020
Group A Streptococcus AdcR Regulon Participates in Bacterial Defense against Host-Mediated Zinc Sequestration and Contributes to Virulence.. 88. 2020
Antibiotic Degradation by Commensal Microbes Shields Pathogens.. 88. 2020
Antibiotic-Induced Shifts in Fecal Microbiota Density and Composition during Hematopoietic Stem Cell Transplantation.. 87. 2019
Diversification and Evolution of Vancomycin-Resistant Enterococcus faecium during Intestinal Domination.. 87. 2019
The Obligate Intracellular Bacterium Orientia tsutsugamushi Targets NLRC5 To Modulate the Major Histocompatibility Complex Class I Pathway.. 87. 2019
Gene Expression Differences in Host Response to Schistosoma haematobium Infection.. 87. 2018
RocA Has Serotype-Specific Gene Regulatory and Pathogenesis Activities in Serotype M28 Group A Streptococcus.. 86. 2018
Signaling by a Conserved Quorum Sensing Pathway Contributes to Growth Ex Vivo and Oropharyngeal Colonization of Human Pathogen Group A Streptococcus.. 86. 2018
Interleukin 1α Is Critical for Resistance against Highly Virulent Aspergillus fumigatus Isolates.. 85. 2017
Streptococcus pneumoniae Colonization Is Required To Alter the Nasal Microbiota in Cigarette Smoke-Exposed Mice.. 85. 2017
Increased Pilus Production Conferred by a Naturally Occurring Mutation Alters Host-Pathogen Interaction in Favor of Carriage in Streptococcus pyogenes.. 85. 2017
Gamma Interferon-Regulated Chemokines in Leishmania donovani Infection in the Liver.. 85. 2016
Genomic Landscape of Intrahost Variation in Group A Streptococcus: Repeated and Abundant Mutational Inactivation of the fabT Gene Encoding a Regulator of Fatty Acid Synthesis.. 84. 2016
Intergenic Variable-Number Tandem-Repeat Polymorphism Upstream of rocA Alters Toxin Production and Enhances Virulence in Streptococcus pyogenes.. 84. 2016
DAP12 Inhibits Pulmonary Immune Responses to Cryptococcus neoformans.. 84. 2016
The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.. 84. 2016
Outer surface protein OspC is an antiphagocytic factor that protects Borrelia burgdorferi from phagocytosis by macrophages.. 83. 2015
The majority of 9,729 group A streptococcus strains causing disease secrete SpeB cysteine protease: pathogenesis implications.. 83. 2015
A Single Amino Acid Replacement in the Sensor Kinase LiaS Contributes to a Carrier Phenotype in Group A Streptococcus.. 83. 2015
Phosphorylation events in the multiple gene regulator of group A Streptococcus significantly influence global gene expression and virulence.. 83. 2015
Natural variant of collagen-like protein a in serotype M3 group a Streptococcus increases adherence and decreases invasive potential.. 83. 2015
Granzyme-mediated regulation of host defense in the liver in experimental Leishmania donovani infection.. 83. 2014
Asymptomatic carriage of group A streptococcus is associated with elimination of capsule production.. 82. 2014
Deficiency of double-strand DNA break repair does not impair Mycobacterium tuberculosis virulence in multiple animal models of infection.. 82. 2014
Identification of point mutations in clinical Staphylococcus aureus strains that produce small-colony variants auxotrophic for menadione.. 82. 2014
Natural variation in the promoter of the gene encoding the Mga regulator alters host-pathogen interactions in group a Streptococcus carrier strains.. 81. 2013
Manganese and zinc regulate virulence determinants in Borrelia burgdorferi.. 81. 2013
Regulatory actions of Toll-like receptor 2 (TLR2) and TLR4 in Leishmania donovani infection in the liver.. 81. 2013
Hookworm excretory/secretory products induce interleukin-4 (IL-4)+ IL-10+ CD4+ T cell responses and suppress pathology in a mouse model of colitis.. 81. 2013
Intestinal microbiota containing Barnesiella species cures vancomycin-resistant Enterococcus faecium colonization.. 81. 2013
Mycobacterial trehalose dimycolate reprograms macrophage global gene expression and activates matrix metalloproteinases.. 81. 2012
Mycobacterium tuberculosis requires phosphate-responsive gene regulation to resist host immunity.. 81. 2012
Cigarette smoke increases Staphylococcus aureus biofilm formation via oxidative stress.. 80. 2012
Mycobacterium tuberculosis lacking all mycolic acid cyclopropanation is viable but highly attenuated and hyperinflammatory in mice.. 80. 2012
Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis.. 80. 2011
Spontaneous phthiocerol dimycocerosate-deficient variants of Mycobacterium tuberculosis are susceptible to gamma interferon-mediated immunity.. 79. 2011
Dispensability of surfactant proteins A and D in immune control of Mycobacterium tuberculosis infection following aerosol challenge of mice.. 79. 2011
Community-wide response of the gut microbiota to enteropathogenic Citrobacter rodentium infection revealed by deep sequencing.. 77. 2009
Role of teichoic acid choline moieties in the virulence of Streptococcus pneumoniae.. 77. 2009
Expression of B-cell activating factor enhances protective immunity of a vaccine against Pseudomonas aeruginosa.. 77. 2009
Adenovirus-mediated delivery of an anti-V antigen monoclonal antibody protects mice against a lethal Yersinia pestis challenge.. 77. 2009
Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages.. 77. 2009
Leptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways.. 77. 2008
Accelerated control of visceral Leishmania donovani infection in interleukin-6-deficient mice.. 76. 2008
Intranasal interleukin-12 therapy inhibits Mycoplasma pneumoniae clearance and sustains airway obstruction in murine pneumonia.. 76. 2007
Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis.. 75. 2007
Respiratory tract infection with Mycoplasma pneumoniae in interleukin-12 knockout mice results in improved bacterial clearance and reduced pulmonary inflammation.. 75. 2006
The circadian clock Period 2 gene regulates gamma interferon production of NK cells in host response to lipopolysaccharide-induced endotoxic shock.. 74. 2006
Responses to Leishmania donovani in mice deficient in interleukin-12 (IL-12), IL-12/IL-23, or IL-18.. 74. 2006
Visceral Leishmania donovani infection in interleukin-13-/- mice.. 74. 2006
Cytosolic phospholipase A2 enzymes are not required by mouse bone marrow-derived macrophages for the control of Mycobacterium tuberculosis in vitro.. 74. 2006
Dihydrolipoamide acyltransferase is critical for Mycobacterium tuberculosis pathogenesis.. 74. 2006
T-helper-2 cytokine responses to Sj97 predict resistance to reinfection with Schistosoma japonicum.. 74. 2006
Distinct CD4+-T-cell responses to live and heat-inactivated Aspergillus fumigatus conidia.. 73. 2005
Induction of protective immunity to anthrax lethal toxin with a nonhuman primate adenovirus-based vaccine in the presence of preexisting anti-human adenovirus immunity.. 73. 2005
Fetuin-A, a hepatocyte-specific protein that binds Plasmodium berghei thrombospondin-related adhesive protein: a potential role in infectivity.. 73. 2005
Role for nucleotide excision repair in virulence of Mycobacterium tuberculosis.. 73. 2005
Similarity of gene expression patterns in human alveolar macrophages in response to Pseudomonas aeruginosa and Burkholderia cepacia.. 73. 2005
Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis.. 73. 2005
Pseudomonas aeruginosa SoxR does not conform to the archetypal paradigm for SoxR-dependent regulation of the bacterial oxidative stress adaptive response.. 73. 2005
Chlamydia pneumoniae enhances cytokine-stimulated human monocyte matrix metalloproteinases through a prostaglandin E2-dependent mechanism.. 73. 2005
A mutant of Mycobacterium tuberculosis H37Rv that lacks expression of antigen 85A is attenuated in mice but retains vaccinogenic potential.. 72. 2004
Identification of Mycobacterium tuberculosis counterimmune (cim) mutants in immunodeficient mice by differential screening.. 72. 2004
Lack of an association between antibodies to Plasmodium falciparum glycosylphosphatidylinositols and malaria-associated placental changes in Cameroonian women with preterm and full-term deliveries.. 72. 2004
Down-modulation of lung immune responses by interleukin-10 and transforming growth factor beta (TGF-beta) and analysis of TGF-beta receptors I and II in active tuberculosis.. 72. 2004
HLA-A2-restricted CD8+-cytotoxic-T-cell responses to novel epitopes in Mycobacterium tuberculosis superoxide dismutase, alanine dehydrogenase, and glutamine synthetase.. 72. 2004
Modulation of T-cell costimulation as immunotherapy or immunochemotherapy in experimental visceral leishmaniasis.. 71. 2003
Interactions of Campylobacter jejuni cytolethal distending toxin subunits CdtA and CdtC with HeLa cells.. 71. 2003
Inactivation of the srtA gene affects localization of surface proteins and decreases adhesion of Streptococcus pneumoniae to human pharyngeal cells in vitro.. 71. 2003
Localized eosinophil degranulation mediates disease in tropical pulmonary eosinophilia.. 71. 2003
Campylobacter jejuni cytolethal distending toxin promotes DNA repair responses in normal human cells.. 71. 2003
Interleukin-1 receptor antagonist gene polymorphism, vaginal interleukin-1 receptor antagonist concentrations, and vaginal ureaplasma urealyticum colonization in pregnant women.. 71. 2003
Decreased infectivity despite unaltered C3 binding by a DeltahbhA mutant of Mycobacterium tuberculosis.. 70. 2002
Peptidoglycan N-acetylglucosamine deacetylase, a putative virulence factor in Streptococcus pneumoniae.. 70. 2002
Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy.. 70. 2002
ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response.. 70. 2002
Antigenic variation of Ehrlichia chaffeensis resulting from differential expression of the 28-kilodalton protein gene family.. 70. 2002
Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes.. 70. 2002
Cytolethal distending toxin demonstrates genotoxic activity in a yeast model.. 69. 2001
Phagocytosis of wild-type Legionella pneumophila occurs through a wortmannin-insensitive pathway.. 69. 2001
Protection against pulmonary infection with Pseudomonas aeruginosa following immunization with P. aeruginosa-pulsed dendritic cells.. 69. 2001
Cyclic nucleotide signaling in Toxoplasma gondii bradyzoite differentiation.. 69. 2001
Mononuclear cell recruitment, granuloma assembly, and response to treatment in experimental visceral leishmaniasis: intracellular adhesion molecule 1-dependent and -independent regulation.. 68. 2000
Visceral leishmaniasis in mice devoid of tumor necrosis factor and response to treatment.. 68. 2000
Disruption of the genes encoding antigen 85A and antigen 85B of Mycobacterium tuberculosis H37Rv: effect on growth in culture and in macrophages.. 68. 2000
Roles of endogenous gamma interferon and macrophage microbicidal mechanisms in host response to chemotherapy in experimental visceral leishmaniasis.. 68. 2000
Secretory leukocyte protease inhibitor interferes with uptake of lipopolysaccharide by macrophages.. 67. 1999
Deacylation of purified lipopolysaccharides by cellular and extracellular components of a sterile rabbit peritoneal inflammatory exudate.. 67. 1999
noxR3, a novel gene from Mycobacterium tuberculosis, protects Salmonella typhimurium from nitrosative and oxidative stress.. 67. 1999
Gamma interferon and interleukin-10 gene expression in synovial tissues from patients with early stages of Chlamydia-associated arthritis and undifferentiated oligoarthritis and from healthy volunteers.. 67. 1999
Green fluorescent protein as a marker in Plasmodium berghei transformation.. 67. 1999
Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila.. 66. 1998
Identification of persistent infection in experimental syphilis by PCR.. 66. 1998
Lipopolysaccharide-related stimuli induce expression of the secretory leukocyte protease inhibitor, a macrophage-derived lipopolysaccharide inhibitor.. 66. 1998
Mice are protected from Helicobacter pylori infection by nasal immunization with attenuated Salmonella typhimurium phoPc expressing urease A and B subunits.. 66. 1998
Mycobacterial growth and sensitivity to H2O2 killing in human monocytes in vitro.. 65. 1997
Evaluation of bacterial survival and phagocyte function with a fluorescence-based microplate assay.. 65. 1997
Perforin, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice.. 65. 1997
Potent CD14-mediated signalling of human leukocytes by Escherichia coli can be mediated by interaction of whole bacteria and host cells without extensive prior release of endotoxin.. 64. 1996
H2O2 induces monocyte apoptosis and reduces viability of Mycobacterium avium-M. intracellulare within cultured human monocytes.. 64. 1996
Multiple host defense defects in failure of C57BL/6 ep/ep (pale ear) mice to resolve visceral Leishmania donovani infection.. 64. 1996
Antibody-independent binding of complement component C1q by Legionella pneumophila.. 63. 1995
Reconstituted high-density lipoprotein neutralizes gram-negative bacterial lipopolysaccharides in human whole blood.. 63. 1995
Gram-positive cell walls stimulate synthesis of tumor necrosis factor alpha and interleukin-6 by human monocytes.. 62. 1994
Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis.. 62. 1994
Effector role of blood monocytes in experimental visceral leishmaniasis.. 61. 1993
Legionella pneumophila lipopolysaccharide activates the classical complement pathway.. 60. 1992
Staphylococcus aureus and derived exotoxins induce nuclear factor kappa B-like activity in murine bone marrow macrophages.. 60. 1992
Asexual development of Cryptosporidium parvum within a differentiated human enterocyte cell line.. 59. 1991
Defect in the tissue cellular immune response: experimental visceral leishmaniasis in euthymic C57BL/6 ep/ep mice.. 58. 1990
Suppression of T-lymphocyte responses to Entamoeba histolytica antigen by immune sera.. 58. 1990
pap-2-encoded fimbriae adhere to the P blood group-related glycosphingolipid stage-specific embryonic antigen 4 in the human kidney.. 58. 1990
Pathophysiologic glucocorticoid elevations promote bacterial translocation after thermal injury.. 58. 1990
Prostaglandin E2 enhances and gamma interferon inhibits germ tube formation in Candida albicans.. 58. 1990
Purified P fimbriae from two cloned gene clusters of a single pyelonephritogenic strain adhere to unique structures in the human kidney.. 57. 1989
Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages.. 57. 1989
Presence of a macrophage-mediated suppressor cell mechanism during cell-mediated immune response in experimental visceral leishmaniasis.. 54. 1986
Activation of the alternative complement pathway by pneumococcal lipoteichoic acid.. 47. 1985
Relationship between extracellular stimulation of intracellular killing and oxygen-dependent microbicidal systems of monocytes.. 47. 1985
Characterization of common virulence plasmids in Yersinia species and their role in the expression of outer membrane proteins.. 43. 1984
Reversible acquisition of a host cell surface membrane antigen by Trypanosoma cruzi.. 40. 1983
Effect of hydrocortisone on macrophage response to lymphokine.. 35. 1982
Cell-mediated immunity in American visceral leishmaniasis: reversible immunosuppression during acute infection.. 33. 1981
In vitro activation of feline complement by feline leukemia virus.. 29. 1980
Monocyte function in human neonates.. 19. 1978
Ribosomal vaccines. I. Immunogenicity of ribosomal fractions isolated from Salmonella typhimurium and Yersinia pestis.. 5. 1972

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Infection and immunity Journal

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