Visceral Leishmania donovani infection in interleukin-13-/- mice. Academic Article uri icon

Overview

abstract

  • Leishmania donovani-infected interleukin-13-/- BALB/c mice showed impaired initial gamma interferon secretion and incomplete granuloma assembly at parasitized liver foci. Nonetheless, control of early parasite replication, resolution of liver infection, and responsiveness to antileishmanial chemotherapy were intact. By itself, interleukin-13 does not appear to materially influence acquired resistance in this intracellular infection.

publication date

  • April 1, 2006

Research

keywords

  • Interleukin-13
  • Leishmania donovani
  • Leishmaniasis, Visceral

Identity

PubMed Central ID

  • PMC1418934

Scopus Document Identifier

  • 33645509111

PubMed ID

  • 16552085

Additional Document Info

volume

  • 74

issue

  • 4