Pharmacotherapy of bipolar disorder in old age: review and recommendations. Review uri icon

Overview

abstract

  • The authors reviewed the evidence-base for pharmacological treatment of mania and bipolar (BP) depression in late life. Treatment benefits and side effects may be modified by age-associated factors, such as neurocognitive impairments. Lithium and divalproex have most often been studied in elderly patients, and both may be efficacious in acute treatment of mania, but there are no controlled efficacy or effectiveness trials. The role of atypical antipsychotic agents remains to be clarified. Similarly, there are no systematic studies of the treatment of BP depression in elderly patients. The authors make suggestions for management and delineate priorities for research.

publication date

  • July 1, 2004

Research

keywords

  • Antipsychotic Agents
  • Bipolar Disorder
  • Lithium Carbonate

Identity

PubMed ID

  • 15249272

Additional Document Info

volume

  • 12

issue

  • 4