Adenovirus-based genetic vaccines for biodefense. Review uri icon

Overview

abstract

  • The robust host responses elicited against transgenes encoded by (E1-)(E3-) adenovirus (Ad) gene transfer vectors can be used to develop Ad-based vectors as platform technologies for vaccines against potential bioterror pathogens. This review focuses on pathogens of major concern as bioterror agents and why Ad vectors are ideal as anti-bioterror vaccine platforms, providing examples from our laboratories of using Ad vectors as vaccines against potential bioterror pathogens and how Ad vectors can be developed to enhance vaccine efficacy in the bioterror war.

publication date

  • February 1, 2005

Research

keywords

  • AIDS Vaccines
  • Adenoviridae
  • Bioterrorism
  • Communicable Disease Control
  • Genetic Therapy
  • HIV Infections

Identity

Scopus Document Identifier

  • 14844303332

PubMed ID

  • 15761256

Additional Document Info

volume

  • 16

issue

  • 2