selected publications
- AAVrh.10 Delivery of Novel APOE2-Christchurch Variant Suppresses Amyloid and Tau Pathology in Alzheimer's Disease Mice. Molecular therapy : the journal of the American Society of Gene Therapy. 2024 Academic Article GET IT
- Suppression of CNS APOE4 Expression by miRNAs Delivered by the S2 AAVrh.10 Capsid-modified AAV Vector. Human gene therapy. 2024 Academic Article GET IT
- Angiogenic Gene Therapy for Refractory Angina: Results of the EXACT Phase 2 Trial. Circulation. Cardiovascular interventions. 2024 Academic Article GET IT
- Management of Select Adverse Events Following Delandistrogene Moxeparvovec Gene Therapy for Patients With Duchenne Muscular Dystrophy. Journal of neuromuscular diseases. 2024 Academic Article GET IT
- Expression and processing of mature human frataxin after gene therapy in mice. Scientific reports. 2024 Academic Article GET IT
- Expression and processing of mature human frataxin after gene therapy in mice. 2023 GET IT
- Predicted deleterious variants in the human genome relevant to gene therapy with adeno-associated virus vectors. Molecular therapy. Methods & clinical development. 2023 Academic Article GET IT
- Assessment of Safety and Biodistribution of AAVrh.10hCLN2 Following Intracisternal Administration in Nonhuman Primates for the Treatment of CLN2 Batten Disease. Human gene therapy. 2023 Academic Article GET IT
- Positron Emission Tomography Quantitative Assessment of Off-Target Whole-Body Biodistribution of I-124-labeled Adeno-associated Virus Capsids Administered to Cerebral Spinal Fluid. Human gene therapy. 2023 Academic Article GET IT
- Serial Sampling of the Small Airway Epithelium to Identify Persistent Smoking-dysregulated Genes. American journal of respiratory and critical care medicine. 2023 Academic Article GET IT
- EXACT Trial: Results of the Phase 1 Dose-Escalation Study. Circulation. Cardiovascular interventions. 2023 Academic Article GET IT
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High apoptotic endothelial microparticle levels measured in asthma with elevated IgE and eosinophils.
Respiratory research.
2023
Letter
GET IT
Times cited: 4 - Assessment of Residual Full-Length SV40 Large T Antigen in Clinical-grade Adeno-associated Virus Vectors Produced in 293T Cells. Human gene therapy. 2023 Academic Article GET IT
- Identification of Safe and Effective Intravenous Dose of AAVrh.10hFXN to Treat the Cardiac Manifestations of Friedreich's Ataxia. Human gene therapy. 2023 Academic Article GET IT
- Use of the Iron Chelator Deferiprone to Restore Function in BAL Fluid Macrophages in Smoking and Chronic Obstructive Pulmonary Disease. American journal of respiratory cell and molecular biology. 2023 Letter GET IT
- Gene Therapy to Treat Osteopenia Associated With Chronic Ethanol Consumption and Aldehyde Dehydrogenase 2 Deficiency. JBMR plus. 2023 Academic Article GET IT
- Safety of Intravenous Administration of an AAV8 Vector Coding for an Oxidation Resistant Human α1-antitrypsin for the Treatment of α1-antitrypsin Deficiency. Human gene therapy. 2023 Academic Article GET IT
- Oral Epithelium Response of Electronic Cigarette Users to Electronic Cigarette. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2022 Academic Article GET IT
- Mixed-Substituted Single-Source Precursors for Si1-xGex Thin Film Deposition. Inorganic chemistry. 2022 Academic Article GET IT
- Evaluating the State of the Science for Adeno-Associated Virus (AAV) Integration:An Integrated Perspective. Molecular therapy : the journal of the American Society of Gene Therapy. 2022 Review GET IT
- Novel MYO5B mutation in microvillous inclusion disease of Syrian ancestry. Cold Spring Harbor molecular case studies. 2022 Academic Article GET IT
- Impaired differentiation of small airway basal stem/progenitor cells in people living with HIV. Scientific reports. 2022 Academic Article GET IT
-
Metabolic and Metabo-Clinical Signatures of Type 2 Diabetes, Obesity, Retinopathy, and Dyslipidemia.
Diabetes.
2022
Academic Article
GET IT
Times cited: 42 - The QChip1 knowledgebase and microarray for precision medicine in Qatar. NPJ genomic medicine. 2022 Academic Article GET IT
- Genetic Modification of the AAV5 Capsid with Lysine Residues Results in a Lung-tropic, Liver-detargeted Gene Transfer Vector. Human gene therapy. 2022 Academic Article GET IT
- Can gene therapy be used to prevent cancer? Gene therapy for aldehyde dehydrogenase 2 deficiency. Cancer gene therapy. 2021 Review GET IT
- Gene therapy in a murine model of chronic eosinophilic leukemia-not otherwise specified (CEL-NOS). Leukemia. 2021 Academic Article GET IT
- Long-term functional correction of cystathionine β-synthase deficiency in mice by adeno-associated viral gene therapy. Journal of inherited metabolic disease. 2021 Academic Article GET IT
- Smoking shifts human small airway epithelium club cells toward a lesser differentiated population. NPJ genomic medicine. 2021 Academic Article GET IT
- Up-regulation of ACE2, the SARS-CoV-2 receptor, in asthmatics on maintenance inhaled corticosteroids. Respiratory research. 2021 Academic Article GET IT
- Epicardial delivery of XC001 gene therapy for refractory angina coronary treatment (The EXACT Trial): Rationale, design, and clinical considerations. American heart journal. 2021 Academic Article GET IT
-
Automated Retinal Layer Segmentation in CLN2-Associated Disease: Commercially Available Software Characterizing a Progressive Maculopathy.
Translational vision science & technology.
2021
Academic Article
GET IT
Times cited: 4 - Gene therapy for a murine model of eosinophilic esophagitis. Allergy. 2021 Academic Article GET IT
-
CREB-dependent LPA-induced signaling initiates a pro-fibrotic feedback loop between small airway basal cells and fibroblasts.
Respiratory research.
2021
Academic Article
GET IT
Times cited: 7 -
Safety of Direct Intraparenchymal AAVrh.10-Mediated Central Nervous System Gene Therapy for Metachromatic Leukodystrophy.
Human gene therapy.
2021
Academic Article
GET IT
Times cited: 24 - Extracellular vesicles from human airway basal cells respond to cigarette smoke extract and affect vascular endothelial cells. Scientific reports. 2021 Academic Article GET IT
-
HIV induces airway basal progenitor cells to adopt an inflammatory phenotype.
Scientific reports.
2021
Academic Article
GET IT
Times cited: 10 -
Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2.
Science translational medicine.
2020
Academic Article
GET IT
Times cited: 49 -
Quantitative Whole-Body Imaging of I-124-Labeled Adeno-Associated Viral Vector Biodistribution in Nonhuman Primates.
Human gene therapy.
2020
Academic Article
GET IT
Times cited: 23 - Cocaine vaccine dAd5GNE protects against moderate daily and high-dose "binge" cocaine use. PloS one. 2020 Academic Article GET IT
- Active immunotherapy and alternative therapeutic modalities for Alzheimer's disease. Alzheimer's & dementia (New York, N. Y.). 2020 Academic Article GET IT
- Reply to Sharma and Zeki: Does Vaping Increase Susceptibility to COVID-19?. American journal of respiratory and critical care medicine. 2020 Article GET IT
-
Association of vitamin D3 and its metabolites in patients with and without type 2 diabetes and their relationship to diabetes complications.
Therapeutic advances in chronic disease.
2020
Academic Article
GET IT
Times cited: 22 -
Dysregulation of club cell biology in idiopathic pulmonary fibrosis.
PloS one.
2020
Academic Article
GET IT
Times cited: 27 -
Gene therapy for alpha 1-antitrypsin deficiency with an oxidant-resistant human alpha 1-antitrypsin.
JCI insight.
2020
Academic Article
GET IT
Times cited: 13 -
Stress-Induced Mouse Model of the Cardiac Manifestations of Friedreich's Ataxia Corrected by AAV-mediated Gene Therapy.
Human gene therapy.
2020
Academic Article
GET IT
Times cited: 2 -
Cell-specific expression of lung disease risk-related genes in the human small airway epithelium.
Respiratory research.
2020
Academic Article
GET IT
Times cited: 24 -
Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium.
American journal of respiratory and critical care medicine.
2020
Academic Article
GET IT
Times cited: 179 -
Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS.
Scientific reports.
2020
Academic Article
GET IT
Times cited: 14 - Qatari Genotype May Contribute to Complications in Type 2 Diabetes. Journal of diabetes research. 2020 Academic Article GET IT
-
Association of vitamin D2 and D3 with type 2 diabetes complications.
BMC endocrine disorders.
2020
Academic Article
GET IT
Times cited: 25 -
Identifying novel associations in GWAS by hierarchical Bayesian latent variable detection of differentially misclassified phenotypes.
BMC bioinformatics.
2020
Academic Article
GET IT
Times cited: 4 - Single-Cell Transcriptome Analysis of Mouse Liver Cell-Specific Tropism and Transcriptional Dysregulation Following Intravenous Administration of AAVrh.10 Vectors. Human gene therapy. 2020 Academic Article GET IT
-
Association of Differing Qatari Genotypes with Vitamin D Metabolites.
International journal of endocrinology.
2020
Academic Article
GET IT
Times cited: 1 -
Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture.
Scientific reports.
2020
Academic Article
GET IT
Times cited: 42 -
Alveolar Macrophage Immunometabolism and Lung Function Impairment in Smoking and Chronic Obstructive Pulmonary Disease.
American journal of respiratory and critical care medicine.
2020
Letter
GET IT
Times cited: 44 - My Pathway to Gene Therapy. Human gene therapy. 2020 Academic Article GET IT
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Systemic Adeno-Associated Virus-Mediated Gene Therapy Prevents the Multiorgan Disorders Associated with Aldehyde Dehydrogenase 2 Deficiency and Chronic Ethanol Ingestion.
Human gene therapy.
2020
Academic Article
GET IT
Times cited: 6 -
Symmetric Age Association of Retinal Degeneration in Patients with CLN2-Associated Batten Disease.
Ophthalmology. Retina.
2020
Academic Article
GET IT
Times cited: 17 -
Anti-Phospho-Tau Gene Therapy for Chronic Traumatic Encephalopathy.
Human gene therapy.
2019
Academic Article
GET IT
Times cited: 4 -
Point of Care Exome Sequencing Reveals Allelic and Phenotypic Heterogeneity Underlying Mendelian disease in Qatar.
Human molecular genetics.
2019
Academic Article
GET IT
Times cited: 2 -
Gene Therapy Correction of Aldehyde Dehydrogenase 2 Deficiency.
Molecular therapy. Methods & clinical development.
2019
Academic Article
GET IT
Times cited: 25 -
Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity.
Respiratory research.
2019
Academic Article
GET IT
Times cited: 35 -
Role of KRAS in regulating normal human airway basal cell differentiation.
Respiratory research.
2019
Academic Article
GET IT
Times cited: 4 -
Exaggerated BMP4 signalling alters human airway basal progenitor cell differentiation to cigarette smoking-related phenotypes.
The European respiratory journal.
2019
Academic Article
GET IT
Times cited: 29 -
Gene therapy for C1 esterase inhibitor deficiency in a Murine Model of Hereditary angioedema.
Allergy.
2019
Academic Article
GET IT
Times cited: 36 -
Ambient Pollution-related Reprogramming of the Human Small Airway Epithelial Transcriptome.
American journal of respiratory and critical care medicine.
2018
Academic Article
GET IT
Times cited: 19 -
Corneal confocal microscopy: Neurologic disease biomarker in Friedreich ataxia.
Annals of neurology.
2018
Academic Article
GET IT
Times cited: 24 -
Ontogeny and Biology of Human Small Airway Epithelial Club Cells.
American journal of respiratory and critical care medicine.
2018
Academic Article
GET IT
Times cited: 72 -
Whole-methylome analysis of circulating monocytes in acute diabetic Charcot foot reveals differentially methylated genes involved in the formation of osteoclasts.
Epigenomics.
2018
Academic Article
GET IT
Times cited: 11 -
Untargeted Metabolite Profiling of Cerebrospinal Fluid Uncovers Biomarkers for Severity of Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2, Batten Disease).
Scientific reports.
2018
Academic Article
GET IT
Times cited: 20 -
Exome sequencing-based identification of novel type 2 diabetes risk allele loci in the Qatari population.
PloS one.
2018
Academic Article
GET IT
Times cited: 7 -
Genome-wide association study of lung function and clinical implication in heavy smokers.
BMC medical genetics.
2018
Academic Article
GET IT
Times cited: 25 -
Disease characteristics and progression in patients with late-infantile neuronal ceroid lipofuscinosis type 2 (CLN2) disease: an observational cohort study.
The Lancet. Child & adolescent health.
2018
Academic Article
GET IT
Times cited: 96 -
Rural Residence and Chronic Obstructive Pulmonary Disease Exacerbations. Analysis of the SPIROMICS Cohort.
Annals of the American Thoracic Society.
2018
Academic Article
GET IT
Times cited: 33 -
At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease.
American journal of respiratory and critical care medicine.
2018
Academic Article
GET IT
Times cited: 202 -
In Vivo Potency Assay for Adeno-Associated Virus-Based Gene Therapy Vectors Using AAVrh.10 as an Example.
Human gene therapy methods.
2018
Academic Article
GET IT
Times cited: 8 -
Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes.
Respiratory research.
2018
Academic Article
GET IT
Times cited: 98 -
p63 Silencing induces reprogramming of cardiac fibroblasts into cardiomyocyte-like cells.
The Journal of thoracic and cardiovascular surgery.
2018
Academic Article
GET IT
Times cited: 14 -
Attenuation of the Niemann-Pick type C2 disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2.
Experimental neurology.
2018
Academic Article
GET IT
Times cited: 10 -
Point-of-care whole-exome sequencing of idiopathic male infertility.
Genetics in medicine : official journal of the American College of Medical Genetics.
2018
Academic Article
GET IT
Times cited: 35 -
AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease.
Human gene therapy. Clinical development.
2018
Academic Article
GET IT
Times cited: 114 -
Mandatory role of HMGA1 in human airway epithelial normal differentiation and post-injury regeneration.
Oncotarget.
2018
Academic Article
GET IT
Times cited: 7 -
A systematic review on the genetics of male infertility in the era of next-generation sequencing.
Arab journal of urology.
2018
Academic Article
GET IT
Times cited: 35 -
Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population.
Nature communications.
2018
Academic Article
GET IT
Times cited: 50 -
Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort.
The Lancet. Respiratory medicine.
2017
Academic Article
GET IT
Times cited: 227 -
Smoking-Dependent Distal-to-Proximal Repatterning of the Adult Human Small Airway Epithelium.
American journal of respiratory and critical care medicine.
2017
Academic Article
GET IT
Times cited: 65 -
Intracerebral gene therapy in children with mucopolysaccharidosis type IIIB syndrome: an uncontrolled phase 1/2 clinical trial.
The Lancet. Neurology.
2017
Academic Article
GET IT
Times cited: 78 -
Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium.
Autophagy.
2017
Academic Article
GET IT
Times cited: 49 -
An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait loci.
PLoS computational biology.
2017
Academic Article
GET IT
Times cited: 8 -
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue-Destructive Phenotype.
Cell reports.
2017
Academic Article
GET IT
Times cited: 11 -
Endothelial Cell Mediated Promotion of Ciliated Cell Differentiation of Human Airway Basal Cells via Insulin and Insulin-Like Growth Factor 1 Receptor Mediated Signaling.
Stem cell reviews and reports.
2017
Academic Article
GET IT
Times cited: 11 -
Waterpipe smoking induces epigenetic changes in the small airway epithelium.
PloS one.
2017
Academic Article
GET IT
Times cited: 27 -
Radioiodinated Capsids Facilitate In Vivo Non-Invasive Tracking of Adeno-Associated Gene Transfer Vectors.
Scientific reports.
2017
Academic Article
GET IT
Times cited: 19 -
Genetic Modification of the Lung Directed Toward Treatment of Human Disease.
Human gene therapy.
2017
Information Resource
GET IT
Times cited: 23 -
Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2016
Academic Article
GET IT
Times cited: 55 -
Compelling evidence for the efficacy of α1-antitrypsin augmentation treatment for α1-antitrypsin deficiency.
The Lancet. Respiratory medicine.
2016
Article
GET IT
Times cited: 2 -
EGF-Amphiregulin Interplay in Airway Stem/Progenitor Cells Links the Pathogenesis of Smoking-Induced Lesions in the Human Airway Epithelium.
Stem cells (Dayton, Ohio).
2016
Academic Article
GET IT
Times cited: 50 -
Gene therapy for metachromatic leukodystrophy.
Journal of neuroscience research.
2016
Review
GET IT
Times cited: 71 -
Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma.
PloS one.
2016
Academic Article
GET IT
Times cited: 18 -
Efficacy of an adenovirus-based anti-cocaine vaccine to reduce cocaine self-administration and reacqusition using a choice procedure in rhesus macaques.
Pharmacology, biochemistry, and behavior.
2016
Academic Article
GET IT
Times cited: 24 -
In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration.
The Journal of thoracic and cardiovascular surgery.
2016
Academic Article
GET IT
Times cited: 43 -
Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers.
American journal of respiratory and critical care medicine.
2016
Academic Article
GET IT
Times cited: 25 -
Correction: Type 2 Diabetes Risk Allele Loci in the Qatari Population.
2016
GET IT
Times cited: 1 -
Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.
PLoS genetics.
2016
Review
GET IT
Times cited: 79 -
JAG1-Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium.
Stem cell reviews and reports.
2016
Academic Article
GET IT
Times cited: 20 -
Sarcoidosis in America. Analysis Based on Health Care Use.
Annals of the American Thoracic Society.
2016
Academic Article
GET IT
Times cited: 106 -
Persistence of circulating endothelial microparticles in COPD despite smoking cessation.
Thorax.
2016
Academic Article
GET IT
Times cited: 42 -
Type 2 Diabetes Risk Allele Loci in the Qatari Population.
PloS one.
2016
Academic Article
GET IT
Times cited: 23 -
The Qatar genome: a population-specific tool for precision medicine in the Middle East.
Human genome variation.
2016
Academic Article
GET IT
Times cited: 87 -
Anti-hIgE gene therapy of peanut-induced anaphylaxis in a humanized murine model of peanut allergy.
The Journal of allergy and clinical immunology.
2016
Academic Article
GET IT
Times cited: 18 -
The Role of Interleukin-23 in the Early Development of Emphysema in HIV1(+) Smokers.
Journal of immunology research.
2016
Academic Article
GET IT
Times cited: 10 -
Progression to COPD in smokers with normal spirometry/low DLCO using different methods to determine normal levels.
The European respiratory journal.
2016
Article
GET IT
Times cited: 3 -
Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.
Neurobiology of aging.
2016
Academic Article
GET IT
Times cited: 31 -
Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort.
Thorax.
2016
Academic Article
GET IT
Times cited: 19 -
POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes.
Journal of immunology (Baltimore, Md. : 1950).
2016
Academic Article
GET IT
Times cited: 42 -
Smoking-Associated Disordering of the Airway Basal Stem/Progenitor Cell Metabotype.
American journal of respiratory cell and molecular biology.
2016
Academic Article
GET IT
Times cited: 29 -
Brain Region-Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease).
AJNR. American journal of neuroradiology.
2016
Academic Article
GET IT
Times cited: 20 -
Cigarette Smoking Induces Changes in Airway Epithelial Expression of Genes Associated with Monogenic Lung Disorders.
American journal of respiratory and critical care medicine.
2016
Article
GET IT
Times cited: 8 -
Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations.
Genome research.
2016
Academic Article
GET IT
Times cited: 72 -
Serum Metabolite Biomarkers Discriminate Healthy Smokers from COPD Smokers.
PloS one.
2015
Academic Article
GET IT
Times cited: 42 -
Risk of COPD with obstruction in active smokers with normal spirometry and reduced diffusion capacity.
The European respiratory journal.
2015
Academic Article
GET IT
Times cited: 109 -
Copy number variations in the genome of the Qatari population.
BMC genomics.
2015
Academic Article
GET IT
Times cited: 9 -
Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells.
Journal of cell science.
2015
Academic Article
GET IT
Times cited: 12 -
Augmentation treatment for α1 antitrypsin deficiency.
Lancet (London, England).
2015
Article
GET IT
Times cited: 6 -
Intracerebral Gene Therapy Using AAVrh.10-hARSA Recombinant Vector to Treat Patients with Early-Onset Forms of Metachromatic Leukodystrophy: Preclinical Feasibility and Safety Assessments in Nonhuman Primates.
Human gene therapy. Clinical development.
2015
Academic Article
GET IT
Times cited: 48 -
Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.
PloS one.
2015
Academic Article
GET IT
Times cited: 61 -
Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.
PloS one.
2015
Academic Article
GET IT
Times cited: 54 -
Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population.
Journal of translational medicine.
2015
Academic Article
GET IT
Times cited: 14 -
Evaluation of compounded bevacizumab prepared for intravitreal injection.
JAMA ophthalmology.
2015
Academic Article
GET IT
Times cited: 32 -
Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma.
Cancer gene therapy.
2014
Academic Article
GET IT
Times cited: 19 -
SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1.
EMBO reports.
2014
Academic Article
GET IT
Times cited: 20 -
FOXJ1 prevents cilia growth inhibition by cigarette smoke in human airway epithelium in vitro.
American journal of respiratory cell and molecular biology.
2014
Academic Article
GET IT
Times cited: 69 -
Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine.
2014
Article
GET IT
Times cited: 85 -
Intra-arterial delivery of AAV vectors to the mouse brain after mannitol mediated blood brain barrier disruption.
Journal of controlled release : official journal of the Controlled Release Society.
2014
Academic Article
GET IT
Times cited: 76 -
Smoking accelerates aging of the small airway epithelium.
Respiratory research.
2014
Academic Article
GET IT
Times cited: 62 -
Phase I/II study of intrapleural administration of a serotype rh.10 replication-deficient adeno-associated virus gene transfer vector expressing the human α1-antitrypsin cDNA to individuals with α1-antitrypsin deficiency.
Human gene therapy. Clinical development.
2014
Academic Article
GET IT
Times cited: 15 -
Comparative efficacy and safety of multiple routes of direct CNS administration of adeno-associated virus gene transfer vector serotype rh.10 expressing the human arylsulfatase A cDNA to nonhuman primates.
Human gene therapy. Clinical development.
2014
Academic Article
GET IT
Times cited: 54 -
AAV-mediated persistent bevacizumab therapy suppresses tumor growth of ovarian cancer.
Gynecologic oncology.
2014
Academic Article
GET IT
Times cited: 25 -
Gene therapy: charting a future course--summary of a National Institutes of Health Workshop, April 12, 2013.
Human gene therapy.
2014
Review
GET IT
Times cited: 13 -
Intracerebral administration of adeno-associated viral vector serotype rh.10 carrying human SGSH and SUMF1 cDNAs in children with mucopolysaccharidosis type IIIA disease: results of a phase I/II trial.
Human gene therapy.
2014
Academic Article
GET IT
Times cited: 149 -
Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia.
Nature medicine.
2014
Academic Article
GET IT
Times cited: 117 -
"Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors.
The Journal of thoracic and cardiovascular surgery.
2014
Academic Article
GET IT
Times cited: 34 -
Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus serotype rh.10 vector expressing the human CLN3 gene.
Human gene therapy.
2014
Academic Article
GET IT
Times cited: 34 -
Fate of systemically administered cocaine in nonhuman primates treated with the dAd5GNE anticocaine vaccine.
Human gene therapy. Clinical development.
2014
Academic Article
GET IT
Times cited: 29 -
Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.
PloS one.
2014
Academic Article
GET IT
Times cited: 61 -
Intraflagellar transport gene expression associated with short cilia in smoking and COPD.
PloS one.
2014
Academic Article
GET IT
Times cited: 62 -
Adenovirus: the first effective in vivo gene delivery vector.
Human gene therapy.
2014
Information Resource
GET IT
Times cited: 270 -
Basal cell origins of smoking-induced airway epithelial disorders.
Cell cycle (Georgetown, Tex.).
2013
Editorial Article
GET IT
Times cited: 20 -
HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors.
Bioinformatics (Oxford, England).
2013
Academic Article
GET IT
Times cited: 17 -
Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity.
Respiratory research.
2013
Academic Article
GET IT
Times cited: 100 -
Are the smoking-induced diseases an acquired form of cystic fibrosis?.
American journal of respiratory and critical care medicine.
2013
Editorial Article
GET IT
Times cited: 3 -
Intrapleural administration of an AAVrh.10 vector coding for human α1-antitrypsin for the treatment of α1-antitrypsin deficiency.
Human gene therapy. Clinical development.
2013
Academic Article
GET IT
Times cited: 39 -
Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function.
BMC medical genetics.
2013
Academic Article
GET IT
Times cited: 9 -
Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.
Human molecular genetics.
2013
Academic Article
GET IT
Times cited: 110 -
Cannulation of the internal carotid artery in mice: a novel technique for intra-arterial delivery of therapeutics.
Journal of neuroscience methods.
2013
Academic Article
GET IT
Times cited: 8 -
Exome sequencing identifies potential risk variants for Mendelian disorders at high prevalence in Qatar.
Human mutation.
2013
Academic Article
GET IT
Times cited: 43 -
Gene therapy to stimulate angiogenesis to treat diffuse coronary artery disease.
Human gene therapy.
2013
Review
GET IT
Times cited: 19 -
Prevalence of the apolipoprotein E Arg145Cys dyslipidemia at-risk polymorphism in African-derived populations.
The American journal of cardiology.
2013
Academic Article
GET IT
Times cited: 14 -
High correlation of the response of upper and lower lobe small airway epithelium to smoking.
PloS one.
2013
Academic Article
GET IT
Times cited: 5 -
Innate immunity and chronic obstructive pulmonary disease: a mini-review.
Gerontology.
2013
Information Resource
GET IT
Times cited: 64 -
Airway basal cells of healthy smokers express an embryonic stem cell signature relevant to lung cancer.
Stem cells (Dayton, Ohio).
2013
Academic Article
GET IT
Times cited: 28 -
Smoking-induced CXCL14 expression in the human airway epithelium links chronic obstructive pulmonary disease to lung cancer.
American journal of respiratory cell and molecular biology.
2013
Academic Article
GET IT
Times cited: 33 -
Spectrum of ocular manifestations in CLN2-associated batten (Jansky-Bielschowsky) disease correlate with advancing age and deteriorating neurological function.
PloS one.
2013
Academic Article
GET IT
Times cited: 38 -
Differential expression of vitamin E and selenium-responsive genes by disease severity in chronic obstructive pulmonary disease.
COPD.
2013
Academic Article
GET IT
Times cited: 9 -
RGD capsid modification enhances mucosal protective immunity of a non-human primate adenovirus vector expressing Pseudomonas aeruginosa OprF.
Clinical and experimental immunology.
2013
Academic Article
GET IT
Times cited: 18 -
Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression.
Human molecular genetics.
2013
Academic Article
GET IT
Times cited: 91 -
RFX3 modulation of FOXJ1 regulation of cilia genes in the human airway epithelium.
Respiratory research.
2013
Academic Article
GET IT
Times cited: 66 -
EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Academic Article
GET IT
Times cited: 82 -
Suppression of nicotine-induced pathophysiology by an adenovirus hexon-based antinicotine vaccine.
Human gene therapy.
2013
Academic Article
GET IT
Times cited: 16 -
Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2013
Academic Article
GET IT
Times cited: 41 -
Lung adenocarcinoma subtypes based on expression of human airway basal cell genes.
The European respiratory journal.
2013
Academic Article
GET IT
Times cited: 34 -
Alpha-1 antitrypsin augmentation therapy.
COPD.
2013
Information Resource
GET IT
Times cited: 27 -
Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats.
Human gene therapy. Clinical development.
2013
Academic Article
GET IT
Times cited: 9 -
Lumbar spine intervertebral disc gene delivery: a pilot study in lewis rats.
HSS journal : the musculoskeletal journal of Hospital for Special Surgery.
2013
Academic Article
GET IT
Times cited: 6 -
Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity.
Human gene therapy.
2012
Academic Article
GET IT
Times cited: 21 -
Long-term follow-up assessment of a phase 1 trial of angiogenic gene therapy using direct intramyocardial administration of an adenoviral vector expressing the VEGF121 cDNA for the treatment of diffuse coronary artery disease.
Human gene therapy.
2012
Academic Article
GET IT
Times cited: 43 -
In vivo cardiac cellular reprogramming efficacy is enhanced by angiogenic preconditioning of the infarcted myocardium with vascular endothelial growth factor.
Journal of the American Heart Association.
2012
Academic Article
GET IT
Times cited: 117 -
Exome sequencing of only seven Qataris identifies potentially deleterious variants in the Qatari population.
PloS one.
2012
Academic Article
GET IT
Times cited: 16 -
Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis.
Human gene therapy methods.
2012
Academic Article
GET IT
Times cited: 84 -
Assessment of disease severity in late infantile neuronal ceroid lipofuscinosis using multiparametric MR imaging.
AJNR. American journal of neuroradiology.
2012
Academic Article
GET IT
Times cited: 17 -
Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.
Human genetics.
2012
Academic Article
GET IT
Times cited: 39 -
Airway epithelial expression of TLR5 is downregulated in healthy smokers and smokers with chronic obstructive pulmonary disease.
Journal of immunology (Baltimore, Md. : 1950).
2012
Academic Article
GET IT
Times cited: 26 -
Correction of brain oligodendrocytes by AAVrh.10 intracerebral gene therapy in metachromatic leukodystrophy mice.
Human gene therapy.
2012
Academic Article
GET IT
Times cited: 75 -
AAV-directed persistent expression of a gene encoding anti-nicotine antibody for smoking cessation.
Science translational medicine.
2012
Academic Article
GET IT
Times cited: 48 -
Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations.
BMC genetics.
2012
Academic Article
GET IT
Times cited: 49 -
In vivo gene transfer strategies to achieve partial correction of von Willebrand disease.
Human gene therapy.
2012
Academic Article
GET IT
Times cited: 17 -
Empirical Bayes conditional independence graphs for regulatory network recovery.
Bioinformatics (Oxford, England).
2012
Academic Article
GET IT
Times cited: 5 -
Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers.
BMC medical genomics.
2012
Academic Article
GET IT
Times cited: 46 -
Novel therapies, high-risk pediatric research, and the prospect of benefit: learning from the ethical disagreements.
Molecular therapy : the journal of the American Society of Gene Therapy.
2012
Academic Article
GET IT
Times cited: 2 -
The challenge of using gene- or cell-based therapies to treat lung disease.
Molecular therapy : the journal of the American Society of Gene Therapy.
2012
Editorial Article
GET IT
Times cited: 2 -
AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior.
Human gene therapy.
2012
Academic Article
GET IT
Times cited: 39 -
Cardiac biointerventions: whatever happened to stem cell and gene therapy?.
Innovations (Philadelphia, Pa.).
2012
Information Resource
GET IT
Times cited: 10 -
Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells.
Cellular and molecular life sciences : CMLS.
2012
Academic Article
GET IT
Times cited: 22 -
RNA-Seq quantification of the human small airway epithelium transcriptome.
BMC genomics.
2012
Academic Article
GET IT
Times cited: 96 -
Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization.
Cell.
2011
Academic Article
GET IT
Times cited: 415 -
Persistent suppression of ocular neovascularization with intravitreal administration of AAVrh.10 coding for bevacizumab.
Human gene therapy.
2011
Academic Article
GET IT
Times cited: 21 -
Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2011
Academic Article
GET IT
Times cited: 74 -
Biologic phenotyping of the human small airway epithelial response to cigarette smoking.
PloS one.
2011
Academic Article
GET IT
Times cited: 63 -
When ethics constrains clinical research: trial design of control arms in "greater than minimal risk" pediatric trials.
Human gene therapy.
2011
Academic Article
GET IT
Times cited: 12 -
The human airway epithelial basal cell transcriptome.
PloS one.
2011
Academic Article
GET IT
Times cited: 154 -
Down-regulation of the canonical Wnt β-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD.
PloS one.
2011
Academic Article
GET IT
Times cited: 90 -
Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers.
American journal of respiratory and critical care medicine.
2011
Academic Article
GET IT
Times cited: 199 -
Glutathione S-transferase copy number variation alters lung gene expression.
The European respiratory journal.
2011
Academic Article
GET IT
Times cited: 18 -
Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer.
Cancer research.
2011
Academic Article
GET IT
Times cited: 35 -
Protective anti-Pseudomonas aeruginosa humoral and cellular mucosal immunity by AdC7-mediated expression of the P. aeruginosa protein OprF.
Vaccine.
2011
Academic Article
GET IT
Times cited: 32 -
Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs.
Molecular therapy : the journal of the American Society of Gene Therapy.
2011
Academic Article
GET IT
Times cited: 56 -
Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium.
Respiratory research.
2010
Academic Article
GET IT
Times cited: 21 -
The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia.
American journal of physiology. Lung cellular and molecular physiology.
2010
Academic Article
GET IT
Times cited: 286 -
Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo.
Cellular and molecular life sciences : CMLS.
2010
Academic Article
GET IT
Times cited: 172 -
Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals.
Chest.
2010
Academic Article
GET IT
Times cited: 47 -
Threshold of biologic responses of the small airway epithelium to low levels of tobacco smoke.
American journal of respiratory and critical care medicine.
2010
Academic Article
GET IT
Times cited: 72 -
Gene therapy for late infantile neuronal ceroid lipofuscinosis: neurosurgical considerations.
Journal of neurosurgery. Pediatrics.
2010
Academic Article
GET IT
Times cited: 60 -
AAVrh.10-mediated genetic delivery of bevacizumab to the pleura to provide local anti-VEGF to suppress growth of metastatic lung tumors.
Gene therapy.
2010
Academic Article
GET IT
Times cited: 44 -
Protective immunity against a lethal respiratory Yersinia pestis challenge induced by V antigen or the F1 capsular antigen incorporated into adenovirus capsid.
Human gene therapy.
2010
Academic Article
GET IT
Times cited: 32 -
Population genetic structure of the people of Qatar.
American journal of human genetics.
2010
Academic Article
GET IT
Times cited: 92 -
Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome?.
American journal of respiratory cell and molecular biology.
2010
Academic Article
GET IT
Times cited: 129 -
Persistent expression of biologically active anti-HER2 antibody by AAVrh.10-mediated gene transfer.
Cancer gene therapy.
2010
Academic Article
GET IT
Times cited: 22 -
Affinity maturation of an anti-V antigen IgG expressed in situ through adenovirus gene delivery confers enhanced protection against Yersinia pestis challenge.
Gene therapy.
2010
Academic Article
GET IT
Times cited: 19 -
Mesothelioma: an inviting but challenging target for gene therapy.
American journal of respiratory cell and molecular biology.
2010
Editorial Article
GET IT
Times cited: 1 -
Smoking is associated with shortened airway cilia.
PloS one.
2009
Academic Article
GET IT
Times cited: 171 -
Disparate oxidant gene expression of airway epithelium compared to alveolar macrophages in smokers.
Respiratory research.
2009
Academic Article
GET IT
Times cited: 19 -
Identification of an exonic splicing silencer in exon 6A of the human VEGF gene.
BMC molecular biology.
2009
Academic Article
GET IT
Times cited: 7 -
Quality control in microarray assessment of gene expression in human airway epithelium.
BMC genomics.
2009
Academic Article
GET IT
Times cited: 74 -
Adenovirus vectors block human immunodeficiency virus-1 replication in human alveolar macrophages by inhibition of the long terminal repeat.
American journal of respiratory cell and molecular biology.
2009
Academic Article
GET IT
Times cited: 4 -
Translating stem cell therapy to the clinic: déjà vu all over again.
Molecular therapy : the journal of the American Society of Gene Therapy.
2009
Editorial Article
GET IT
Times cited: 6 -
Transient overexpression of sonic hedgehog alters the architecture and mechanical properties of trabecular bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
2009
Academic Article
GET IT
Times cited: 19 -
Trachea epithelium as a "canary" for cigarette smoking-induced biologic phenotype of the small airway epithelium.
Clinical and translational science.
2009
Academic Article
GET IT
Times cited: 14 -
Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease.
Journal of immunology (Baltimore, Md. : 1950).
2009
Academic Article
GET IT
Times cited: 330 -
Up-regulation of alveolar macrophage matrix metalloproteinases in HIV1(+) smokers with early emphysema.
Journal of leukocyte biology.
2009
Academic Article
GET IT
Times cited: 42 -
A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.
Nature cell biology.
2009
Academic Article
GET IT
Times cited: 571 -
Genetic delivery of bevacizumab to suppress vascular endothelial growth factor-induced high-permeability pulmonary edema.
Human gene therapy.
2009
Academic Article
GET IT
Times cited: 25 -
Sonic hedgehog expands diaphyseal trabecular bone altering bone marrow niche and lymphocyte compartment.
Molecular therapy : the journal of the American Society of Gene Therapy.
2009
Academic Article
GET IT
Times cited: 11 -
Expression of B-cell activating factor enhances protective immunity of a vaccine against Pseudomonas aeruginosa.
Infection and immunity.
2009
Academic Article
GET IT
Times cited: 23 -
Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells.
Respiratory research.
2009
Academic Article
GET IT
Times cited: 31 -
Coordinate control of expression of Nrf2-modulated genes in the human small airway epithelium is highly responsive to cigarette smoking.
Molecular medicine (Cambridge, Mass.).
2009
Academic Article
GET IT
Times cited: 81 -
Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing.
Human gene therapy.
2009
Academic Article
GET IT
Times cited: 56 -
Cigarette smoking induces overexpression of a fat-depleting gene AZGP1 in the human.
Chest.
2009
Academic Article
GET IT
Times cited: 33 -
Emphysema mediated by lung overexpression of ADAM10.
Clinical and translational science.
2009
Academic Article
GET IT
Times cited: 9 -
Adenovirus-mediated delivery of an anti-V antigen monoclonal antibody protects mice against a lethal Yersinia pestis challenge.
Infection and immunity.
2009
Academic Article
GET IT
Times cited: 30 -
Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine.
2008
Academic Article
GET IT
Times cited: 159 -
Decreased expression of intelectin 1 in the human airway epithelium of smokers compared to nonsmokers.
Journal of immunology (Baltimore, Md. : 1950).
2008
Academic Article
GET IT
Times cited: 38 -
Dysfunctional glycogen storage in a mouse model of alpha1-antitrypsin deficiency.
American journal of respiratory cell and molecular biology.
2008
Academic Article
GET IT
Times cited: 9 -
Overexpression of apoptotic cell removal receptor MERTK in alveolar macrophages of cigarette smokers.
American journal of respiratory cell and molecular biology.
2008
Academic Article
GET IT
Times cited: 50 -
Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV.
Virology.
2008
Academic Article
GET IT
Times cited: 44 -
Treatment of late infantile neuronal ceroid lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA.
Human gene therapy.
2008
Academic Article
GET IT
Times cited: 295 -
Survival advantage of neonatal CNS gene transfer for late infantile neuronal ceroid lipofuscinosis.
Experimental neurology.
2008
Academic Article
GET IT
Times cited: 60 -
Variability in small airway epithelial gene expression among normal smokers.
Chest.
2008
Academic Article
GET IT
Times cited: 47 -
Genetic delivery of the murine equivalent of bevacizumab (avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice.
Human gene therapy.
2008
Academic Article
GET IT
Times cited: 13 -
Progress and prospects: gene therapy for performance and appearance enhancement.
Gene therapy.
2008
Information Resource
GET IT
Times cited: 11 -
Rapid/sustained anti-anthrax passive immunity mediated by co-administration of Ad/AAV.
Molecular therapy : the journal of the American Society of Gene Therapy.
2007
Academic Article
GET IT
Times cited: 36 -
Ablation of tumor-derived stem cells transplanted to the central nervous system by genetic modification of embryonic stem cells with a suicide gene.
Human gene therapy.
2007
Academic Article
GET IT
Times cited: 38 -
Protective immunity to pseudomonas aeruginosa induced with a capsid-modified adenovirus expressing P. aeruginosa OprF.
Journal of virology.
2007
Academic Article
GET IT
Times cited: 54 -
Neurological deterioration in late infantile neuronal ceroid lipofuscinosis.
Neurology.
2007
Academic Article
GET IT
Times cited: 69 -
Assessing disease severity in late infantile neuronal ceroid lipofuscinosis using quantitative MR diffusion-weighted imaging.
AJNR. American journal of neuroradiology.
2007
Academic Article
GET IT
Times cited: 25 -
Intracellular trafficking of adenovirus: many means to many ends.
Advanced drug delivery reviews.
2007
Information Resource
GET IT
Times cited: 81 -
Human embryonic stem cells and gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy.
2007
Information Resource
GET IT
Times cited: 45 -
Upregulation of pirin expression by chronic cigarette smoking is associated with bronchial epithelial cell apoptosis.
Respiratory research.
2007
Academic Article
GET IT
Times cited: 60 -
Interaction of Pneumocystis carinii with dendritic cells and resulting host responses to P. carinii.
Journal of immunotherapy (Hagerstown, Md. : 1997).
2007
Academic Article
GET IT
Times cited: 9 -
Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 rhesus macaque-derived adeno-associated virus vector.
Molecular therapy : the journal of the American Society of Gene Therapy.
2006
Academic Article
GET IT
Times cited: 125 -
Responses of the human airway epithelium transcriptome to in vivo injury.
Physiological genomics.
2006
Academic Article
GET IT
Times cited: 36 -
Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers.
Cancer research.
2006
Academic Article
GET IT
Times cited: 62 -
Modification of gene expression of the small airway epithelium in response to cigarette smoking.
Journal of molecular medicine (Berlin, Germany).
2006
Academic Article
GET IT
Times cited: 152 -
Neutralized adenovirus-immune complexes can mediate effective gene transfer via an Fc receptor-dependent infection pathway.
Journal of virology.
2006
Academic Article
GET IT
Times cited: 32 -
Protective immunity against respiratory tract challenge with Yersinia pestis in mice immunized with an adenovirus-based vaccine vector expressing V antigen.
The Journal of infectious diseases.
2006
Academic Article
GET IT
Times cited: 44 -
A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes.
Journal of virology.
2006
Academic Article
GET IT
Times cited: 49 -
Epitopes expressed in different adenovirus capsid proteins induce different levels of epitope-specific immunity.
Journal of virology.
2006
Academic Article
GET IT
Times cited: 62 -
Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes.
Nature medicine.
2006
Academic Article
GET IT
Times cited: 579 -
Correction of a murine model of von Willebrand disease by gene transfer.
Blood.
2006
Academic Article
GET IT
Times cited: 27 -
Adenoviral gene transfer of stromal cell-derived factor-1 to murine tumors induces the accumulation of dendritic cells and suppresses tumor growth.
Cancer research.
2006
Academic Article
GET IT
Times cited: 27 -
Genetic medicines: treatment strategies for hereditary disorders.
Nature reviews. Genetics.
2006
Information Resource
GET IT
Times cited: 124 -
Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking.
Journal of molecular medicine (Berlin, Germany).
2006
Academic Article
GET IT
Times cited: 78 -
Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro.
Bone.
2006
Academic Article
GET IT
Times cited: 122 -
Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2006
Academic Article
GET IT
Times cited: 118 -
Genetic medicine strategies to protect against bioterrorism.
Transactions of the American Clinical and Climatological Association.
2006
Review
GET IT
Times cited: 4 -
Safety of direct administration of AAV2(CU)hCLN2, a candidate treatment for the central nervous system manifestations of late infantile neuronal ceroid lipofuscinosis, to the brain of rats and nonhuman primates.
Human gene therapy.
2005
Academic Article
GET IT
Times cited: 39 -
High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses.
Molecular therapy : the journal of the American Society of Gene Therapy.
2005
Academic Article
GET IT
Times cited: 98 -
AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL.
Gene therapy.
2005
Academic Article
GET IT
Times cited: 58 -
Alteration of splicing signals in a genomic/cDNA hybrid VEGF gene to modify the ratio of expressed VEGF isoforms enhances safety of angiogenic gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy.
2005
Academic Article
GET IT
Times cited: 25 -
Induction of protective immunity to anthrax lethal toxin with a nonhuman primate adenovirus-based vaccine in the presence of preexisting anti-human adenovirus immunity.
Infection and immunity.
2005
Academic Article
GET IT
Times cited: 52 -
Intrapleural 'outside-in' gene therapy: therapeutics for organs of the chest via gene transfer to the pleura.
Current opinion in molecular therapeutics.
2005
Information Resource
GET IT
Times cited: 6 -
Osteopetrotic mouse stroma with thrombopoietin, c-kit ligand, and flk-2 ligand supports long-term mobilized CD34+ hematopoiesis in vitro.
Stem cells and development.
2005
Academic Article
GET IT
Times cited: 21 -
Gene transfer of the vascular endothelial growth factor receptor flt-1 suppresses pulmonary metastasis associated with lung growth.
American journal of respiratory cell and molecular biology.
2005
Academic Article
GET IT
Times cited: 12 -
Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders.
Human gene therapy.
2005
Review
GET IT
Times cited: 27 -
Enhanced efficacy of cholesterol-minus sonic hedgehog in postnatal skin.
Molecular therapy : the journal of the American Society of Gene Therapy.
2005
Academic Article
GET IT
Times cited: 7 -
Similarity of gene expression patterns in human alveolar macrophages in response to Pseudomonas aeruginosa and Burkholderia cepacia.
Infection and immunity.
2005
Academic Article
GET IT
Times cited: 7 -
Thrombopoietin gene transfer-mediated enhancement of angiogenic responses to acute ischemia.
Circulation research.
2005
Academic Article
GET IT
Times cited: 23 -
VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedema.
The European respiratory journal.
2005
Academic Article
GET IT
Times cited: 47 -
Identification of murine CD8 T cell epitopes in codon-optimized SARS-associated coronavirus spike protein.
Virology.
2005
Academic Article
GET IT
Times cited: 65 -
Adenovirus vector E4 gene regulates connexin 40 and 43 expression in endothelial cells via PKA and PI3K signal pathways.
Circulation research.
2005
Academic Article
GET IT
Times cited: 21 -
Mortality in individuals with severe deficiency of alpha1-antitrypsin: findings from the National Heart, Lung, and Blood Institute Registry.
Chest.
2005
Academic Article
GET IT
Times cited: 59 -
Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid.
The Journal of clinical investigation.
2005
Academic Article
GET IT
Times cited: 96 -
Neurotrophins promote revascularization by local recruitment of TrkB+ endothelial cells and systemic mobilization of hematopoietic progenitors.
The Journal of clinical investigation.
2005
Academic Article
GET IT
Times cited: 219 -
Protective immunity against alpha-cobratoxin following a single administration of a genetic vaccine encoding a non-toxic cobratoxin variant.
Human gene therapy.
2005
Academic Article
GET IT
Times cited: 6 -
Adenovirus-based genetic vaccines for biodefense.
Human gene therapy.
2005
Review
GET IT
Times cited: 42 -
Passive immunotherapy for anthrax toxin mediated by an adenovirus expressing an anti-protective antigen single-chain antibody.
Molecular therapy : the journal of the American Society of Gene Therapy.
2005
Academic Article
GET IT
Times cited: 26 -
Gene transfer-mediated pre-mRNA segmental trans-splicing as a strategy to deliver intracellular toxins for cancer therapy.
Cancer research.
2005
Academic Article
GET IT
Times cited: 23 -
Intrapleural administration of a serotype 5 adeno-associated virus coding for alpha1-antitrypsin mediates persistent, high lung and serum levels of alpha1-antitrypsin.
Molecular therapy : the journal of the American Society of Gene Therapy.
2004
Academic Article
GET IT
Times cited: 39 -
The bronchopulmonary pathology of alpha-1 antitrypsin (AAT) deficiency: findings of the Death Review Committee of the national registry for individuals with Severe Deficiency of Alpha-1 Antitrypsin.
Human pathology.
2004
Academic Article
GET IT
Times cited: 49 -
Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis.
Human gene therapy.
2004
Academic Article
GET IT
Times cited: 100 -
Coexpression of herpesviral thymidine kinase reporter gene and VEGF gene for noninvasive monitoring of therapeutic gene transfer: an in vitro evaluation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2004
Academic Article
GET IT
Times cited: 18 -
Homozygous deletion of early growth response 1 gene and critical limb ischemia after vascular ligation in mice: evidence for a central role in vascular homeostasis.
The Journal of thoracic and cardiovascular surgery.
2004
Academic Article
GET IT
Times cited: 19 -
Macaque model for severe acute respiratory syndrome.
Journal of virology.
2004
Academic Article
GET IT
Times cited: 107 -
Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.
Journal of virology.
2004
Academic Article
GET IT
Times cited: 115 -
Cytoplasmic dynein mediates adenovirus binding to microtubules.
Journal of virology.
2004
Academic Article
GET IT
Times cited: 119 -
Effect of inhibition of multiple steps of angiogenesis in syngeneic murine pleural mesothelioma.
The Annals of thoracic surgery.
2004
Academic Article
GET IT
Times cited: 19 -
Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
2004
Academic Article
GET IT
Times cited: 152 -
Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium.
Circulation.
2004
Academic Article
GET IT
Times cited: 98 -
Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells.
Journal of virology.
2004
Academic Article
GET IT
Times cited: 57 -
Trans-splicing repair of CD40 ligand deficiency results in naturally regulated correction of a mouse model of hyper-IgM X-linked immunodeficiency.
Nature medicine.
2004
Academic Article
GET IT
Times cited: 72 -
Angiogenic pretreatment improves the efficacy of cellular cardiomyoplasty performed with fetal cardiomyocyte implantation.
The Journal of thoracic and cardiovascular surgery.
2004
Academic Article
GET IT
Times cited: 65 -
Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses.
Journal of virology.
2004
Academic Article
GET IT
Times cited: 76 -
Adenoviral-mediated transfer of vascular endothelial growth factor 121 cDNA enhances myocardial perfusion and exercise performance in the nonischemic state.
The Journal of thoracic and cardiovascular surgery.
2004
Academic Article
GET IT
Times cited: 17 -
Augmenting major histocompatibility complex class I expression by murine tumors in vivo enhances antitumor immunity induced by an active immunotherapy strategy.
The Journal of thoracic and cardiovascular surgery.
2004
Academic Article
GET IT
Times cited: 17 -
Adenovirus-mediated transfer of a minigene expressing multiple isoforms of VEGF is more effective at inducing angiogenesis than comparable vectors expressing individual VEGF cDNAs.
Molecular therapy : the journal of the American Society of Gene Therapy.
2004
Academic Article
GET IT
Times cited: 46 -
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis.
Nature medicine.
2003
Academic Article
GET IT
Times cited: 598 -
Adenovirus E4 gene promotes selective endothelial cell survival and angiogenesis via activation of the vascular endothelial-cadherin/Akt signaling pathway.
The Journal of biological chemistry.
2003
Academic Article
GET IT
Times cited: 38 -
Association of adenovirus with the microtubule organizing center.
Journal of virology.
2003
Academic Article
GET IT
Times cited: 45 -
In vivo trans-splicing of 5' and 3' segments of pre-mRNA directed by corresponding DNA sequences delivered by gene transfer.
Molecular therapy : the journal of the American Society of Gene Therapy.
2003
Academic Article
GET IT
Times cited: 27 -
Protective immunity evoked against anthrax lethal toxin after a single intramuscular administration of an adenovirus-based vaccine encoding humanized protective antigen.
Human gene therapy.
2003
Academic Article
GET IT
Times cited: 58 -
Cisplatin augments cytotoxic T-lymphocyte-mediated antitumor immunity in poorly immunogenic murine lung cancer.
The Journal of thoracic and cardiovascular surgery.
2003
Academic Article
GET IT
Times cited: 37 -
Sampling-dependent up-regulation of gene expression in sequential samples of human airway epithelial cells.
Molecular medicine (Cambridge, Mass.).
2003
Academic Article
GET IT
Times cited: 9 -
Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
2003
Academic Article
GET IT
Times cited: 146 -
In vivo gene transfer of pigment epithelium-derived factor inhibits tumor growth in syngeneic murine models of thoracic malignancies.
The Journal of thoracic and cardiovascular surgery.
2003
Academic Article
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Times cited: 45 -
Green fluorescent protein selectively induces HSP70-mediated up-regulation of COX-2 expression in endothelial cells.
Blood.
2003
Academic Article
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Times cited: 46 -
Augmentation therapy with alpha1-antitrypsin: patterns of use and adverse events.
Chest.
2003
Academic Article
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Times cited: 74 -
Variability of antioxidant-related gene expression in the airway epithelium of cigarette smokers.
American journal of respiratory cell and molecular biology.
2003
Academic Article
GET IT
Times cited: 174 -
Monoallelic up-regulation of the imprinted H19 gene in airway epithelium of phenotypically normal cigarette smokers.
Cancer research.
2003
Academic Article
GET IT
Times cited: 51 -
Asthma features in severe alpha1-antitrypsin deficiency: experience of the National Heart, Lung, and Blood Institute Registry.
Chest.
2003
Academic Article
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Times cited: 63 -
Intratumoral expression of macrophage-derived chemokine induces CD4+ T cell-independent antitumor immunity in mice.
Journal of immunotherapy (Hagerstown, Md. : 1997).
2003
Academic Article
GET IT
Times cited: 12 -
Localized eosinophil degranulation mediates disease in tropical pulmonary eosinophilia.
Infection and immunity.
2003
Academic Article
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Times cited: 36 -
Adenoviral-mediated gene transfer of vascular endothelial growth factor in critical limb ischemia: safety results from a phase I trial.
Vascular medicine (London, England).
2003
Academic Article
GET IT
Times cited: 60 -
Adenovirus vector-mediated overexpression of a truncated form of the p65 nuclear factor kappa B cDNA in dendritic cells enhances their function resulting in immune-mediated suppression of preexisting murine tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2002
Academic Article
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Times cited: 13 -
Apoptosis induced by Pseudomonas aeruginosa in antigen presenting cells is diminished by genetic modification with CD40 ligand.
Pediatric research.
2002
Academic Article
GET IT
Times cited: 19 -
Phase I study of direct administration of a replication deficient adenovirus vector containing the vascular endothelial growth factor cDNA (CI-1023) to patients with claudication.
The American journal of cardiology.
2002
Academic Article
GET IT
Times cited: 49 -
Gene transfer to the pleural mesothelium as a strategy to deliver proteins to the lung parenchyma.
Human gene therapy.
2002
Academic Article
GET IT
Times cited: 16 -
In vivo enhanced expression of patched dampens the sonic hedgehog pathway.
Molecular therapy : the journal of the American Society of Gene Therapy.
2002
Academic Article
GET IT
Times cited: 10 -
Inhibition of HIV-1 replication in alveolar macrophages by adenovirus gene transfer vectors.
American journal of respiratory cell and molecular biology.
2002
Academic Article
GET IT
Times cited: 2 -
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment.
Nature medicine.
2002
Academic Article
GET IT
Times cited: 566 -
Fatty acid modification of the coxsackievirus and adenovirus receptor.
Journal of virology.
2002
Academic Article
GET IT
Times cited: 28 -
Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac performance in a pacing model of congestive heart failure.
The Journal of thoracic and cardiovascular surgery.
2002
Academic Article
GET IT
Times cited: 37 -
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand.
Cell.
2002
Academic Article
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Times cited: 1552 - Predicting tuberculosis at hospital admission. Archives of internal medicine. 2002 Article GET IT
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Effect of adenovirus gene transfer vectors on the immunologic functions of mouse dendritic cells.
Molecular therapy : the journal of the American Society of Gene Therapy.
2002
Academic Article
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Times cited: 45 - Adenovirus vector-mediated transfer of the vascular endothelial growth factor cDNA to healing abdominal fascia enhances vascularity and bursting strength in mice with normal and impaired wound healing. Surgery. 2002 Academic Article GET IT
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Ex vivo expansion of stem and progenitor cells in co-culture of mobilized peripheral blood CD34+ cells on human endothelium transfected with adenovectors expressing thrombopoietin, c-kit ligand, and Flt-3 ligand.
Journal of hematotherapy & stem cell research.
2002
Academic Article
GET IT
Times cited: 23 -
Formation of vascularized meniscal tissue by combining gene therapy with tissue engineering.
Tissue engineering.
2002
Academic Article
GET IT
Times cited: 85 -
Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions.
Human gene therapy.
2002
Academic Article
GET IT
Times cited: 71 -
Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions.
Human gene therapy.
2002
Academic Article
GET IT
Times cited: 123 - Effect of adenovirus-mediated expression of Sonic hedgehog gene on hair regrowth in mice with chemotherapy-induced alopecia. Journal of the National Cancer Institute. 2001 Academic Article GET IT
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Intratumoral administration of low doses of an adenovirus vector encoding tumor necrosis factor alpha together with naive dendritic cells elicits significant suppression of tumor growth without toxicity.
Human gene therapy.
2001
Academic Article
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Times cited: 37 -
Feasibility of gene therapy for late neuronal ceroid lipofuscinosis.
Archives of neurology.
2001
Information Resource
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Times cited: 24 -
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth.
Nature medicine.
2001
Academic Article
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Times cited: 1638 -
Upregulation of transcription factors in lung in the early phase of postpneumonectomy lung growth.
American journal of physiology. Lung cellular and molecular physiology.
2001
Academic Article
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Times cited: 41 -
Combined intratumoral injection of bone marrow-derived dendritic cells and systemic chemotherapy to treat pre-existing murine tumors.
Cancer research.
2001
Academic Article
GET IT
Times cited: 110 -
Adenovirus gene transfer vectors inhibit growth of lymphatic tumor metastases independent of a therapeutic transgene.
Human gene therapy.
2001
Academic Article
GET IT
Times cited: 11 -
Antigen-pulsed dendritic cells expressing macrophage-derived chemokine elicit Th2 responses and promote specific humoral immunity.
The Journal of clinical investigation.
2001
Academic Article
GET IT
Times cited: 37 -
Enhanced matrix synthesis and in vitro formation of cartilage-like tissue by genetically modified chondrocytes expressing BMP-7.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
2001
Academic Article
GET IT
Times cited: 63 -
Adenovirus-mediated gene transfer of VEGF(121) improves lower-extremity endothelial function and flow reserve.
Circulation.
2001
Academic Article
GET IT
Times cited: 111 -
Apical localization of the coxsackie-adenovirus receptor by glycosyl-phosphatidylinositol modification is sufficient for adenovirus-mediated gene transfer through the apical surface of human airway epithelia.
Journal of virology.
2001
Academic Article
GET IT
Times cited: 48 -
Cross-strain protection against clinical and laboratory strains of Pseudomonas aeruginosa mediated by dendritic cells genetically modified to express CD40 ligand and pulsed with specific strains of Pseudomonas aeruginosa.
Human gene therapy.
2001
Academic Article
GET IT
Times cited: 11 -
Protection against pulmonary infection with Pseudomonas aeruginosa following immunization with P. aeruginosa-pulsed dendritic cells.
Infection and immunity.
2001
Academic Article
GET IT
Times cited: 45 -
Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle.
Molecular therapy : the journal of the American Society of Gene Therapy.
2001
Academic Article
GET IT
Times cited: 81 -
Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells.
Blood.
2001
Academic Article
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Times cited: 451 -
The use of the L-plastin promoter for adenoviral-mediated, tumor-specific gene expression in ovarian and bladder cancer cell lines.
Cancer research.
2001
Academic Article
GET IT
Times cited: 60 -
Infection of endothelium with E1(-)E4(+), but not E1(-)E4(-), adenovirus gene transfer vectors enhances leukocyte adhesion and migration by modulation of ICAM-1, VCAM-1, CD34, and chemokine expression.
Circulation research.
2001
Academic Article
GET IT
Times cited: 27 -
Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells.
The Journal of experimental medicine.
2001
Academic Article
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Times cited: 622 - Are fewer patient isolations justified for active tuberculosis?. Archives of internal medicine. 2001 Article GET IT
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Compartmentalization of vascular endothelial growth factor to the epithelial surface of the human lung.
Molecular medicine (Cambridge, Mass.).
2001
Academic Article
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Times cited: 109 -
Research opportunities and advances in lung disease.
JAMA.
2001
Academic Article
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Times cited: 11 -
Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein.
Journal of virology.
2001
Academic Article
GET IT
Times cited: 121 -
Host responses and persistence of vector genome following intrabronchial administration of an E1(-)E3(-) adenovirus gene transfer vector to normal individuals.
Molecular therapy : the journal of the American Society of Gene Therapy.
2001
Academic Article
GET IT
Times cited: 27 -
Percutaneous endocardial transfer and expression of genes to the myocardium utilizing fluoroscopic guidance.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.
2001
Academic Article
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Times cited: 26 -
Rapid assessment of adenovirus serum neutralizing antibody titer based on quantitative, morphometric evaluation of capsid binding and intracellular trafficking: population analysis of adenovirus capsid association with cells is predictive of adenovirus infectivity.
Journal of virology.
2001
Academic Article
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Times cited: 20 - Adenoviral-vector-mediated gene transfer to dendritic cells. Methods in molecular medicine. 2001 Academic Article GET IT
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Manipulation of the cytoplasmic and transmembrane domains alters cell surface levels of the coxsackie-adenovirus receptor and changes the efficiency of adenovirus infection.
Human gene therapy.
2001
Academic Article
GET IT
Times cited: 22 -
Persistent, antigen-specific, therapeutic antitumor immunity by dendritic cells genetically modified with an adenoviral vector to express a model tumor antigen.
Gene therapy.
2000
Academic Article
GET IT
Times cited: 20 -
Use of quantitative TaqMan real-time PCR to track the time-dependent distribution of gene transfer vectors in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy.
2000
Academic Article
GET IT
Times cited: 46 -
Tumor regression induced by intratumor administration of adenovirus vector expressing CD40 ligand and naive dendritic cells.
Cancer research.
2000
Academic Article
GET IT
Times cited: 57 -
Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4+ T cells.
Nature medicine.
2000
Academic Article
GET IT
Times cited: 73 -
Downregulation of CXCR4 gene expression in primary human endothelial cells following infection with E1(-)E4(+) adenovirus gene transfer vectors.
Molecular therapy : the journal of the American Society of Gene Therapy.
2000
Academic Article
GET IT
Times cited: 8 -
Evaluation of clinical parameters to predict Mycobacterium tuberculosis in inpatients.
Archives of internal medicine.
2000
Academic Article
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Times cited: 61 -
Adenoviral vector-mediated gene transfer to primitive human hematopoietic progenitor cells: assessment of transduction and toxicity in long-term culture.
Blood.
2000
Academic Article
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Times cited: 24 -
Dendritic cells modified to express CD40 ligand elicit therapeutic immunity against preexisting murine tumors.
Blood.
2000
Academic Article
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Times cited: 121 -
Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema.
American journal of respiratory cell and molecular biology.
2000
Academic Article
GET IT
Times cited: 227 -
Nerve growth factor-induced neuronal differentiation requires generation of Rac1-regulated reactive oxygen species.
The Journal of biological chemistry.
2000
Academic Article
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Times cited: 218 -
Macrophage inflammatory protein 3alpha transgene attracts dendritic cells to established murine tumors and suppresses tumor growth.
The Journal of clinical investigation.
2000
Academic Article
GET IT
Times cited: 153 -
Human gene marker/therapy clinical protocols.
Human gene therapy.
2000
Academic Article
GET IT
Times cited: 38 -
Adenovirus vector-mediated gene transfer to regional lymph nodes.
Human gene therapy.
2000
Academic Article
GET IT
Times cited: 28 -
Feasibility of a clinical trial of augmentation therapy for alpha(1)-antitrypsin deficiency. The Alpha 1-Antitrypsin Deficiency Registry Study Group.
American journal of respiratory and critical care medicine.
2000
Academic Article
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Times cited: 56 - Immunolocalization of proliferating cells in the rabbit iliac artery after balloon angioplasty. Journal of vascular and interventional radiology : JVIR. 2000 Academic Article GET IT
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Coarse spray delivery to a localized region of the pulmonary airways for gene therapy.
Human gene therapy.
2000
Academic Article
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Times cited: 22 -
Dynein- and microtubule-mediated translocation of adenovirus serotype 5 occurs after endosomal lysis.
Human gene therapy.
2000
Academic Article
GET IT
Times cited: 212 -
Free cholesterol enhances adenoviral vector gene transfer and expression in CAR-deficient cells.
Molecular therapy : the journal of the American Society of Gene Therapy.
2000
Academic Article
GET IT
Times cited: 35 -
Human gene marker/therapy clinical protocols.
Human gene therapy.
1999
Academic Article
GET IT
Times cited: 31 -
Bad for cats, good for humans? Modified feline immunodeficiency virus for gene therapy.
The Journal of clinical investigation.
1999
Article
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Times cited: 6 -
Granulocyte-macrophage colony-stimulating factor gene transfer to dendritic cells or epidermal cells augments their antigen-presenting function including induction of anti-tumor immunity.
The Journal of investigative dermatology.
1999
Academic Article
GET IT
Times cited: 22 -
Induction of endogenous genes following infection of human endothelial cells with an E1(-) E4(+) adenovirus gene transfer vector.
Journal of virology.
1999
Academic Article
GET IT
Times cited: 28 -
Cellular immune responses of healthy individuals to intradermal administration of an E1-E3- adenovirus gene transfer vector.
Human gene therapy.
1999
Academic Article
GET IT
Times cited: 62 -
Enhanced liver uptake of opsonized red blood cells after in vivo transfer of FcgammaRIIA cDNA to the liver.
Blood.
1999
Academic Article
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Times cited: 3 -
Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus.
The Journal of clinical investigation.
1999
Academic Article
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Times cited: 210 -
Regional treatment of hepatic micrometastasis by adenovirus vector-mediated delivery of interleukin-2 and interleukin-12 cDNAs to the hepatic parenchyma.
Cancer gene therapy.
1999
Academic Article
GET IT
Times cited: 18 -
Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog.
The Journal of clinical investigation.
1999
Academic Article
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Times cited: 224 -
Specific binding of the adenovirus capsid to the nuclear envelope.
Human gene therapy.
1999
Academic Article
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Times cited: 30 -
Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease.
Circulation.
1999
Academic Article
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Times cited: 590 -
Augmentation of pulmonary host defense against Pseudomonas by FcgammaRIIA cDNA transfer to the respiratory epithelium.
The Journal of clinical investigation.
1999
Academic Article
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Times cited: 5 -
Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs.
Journal of virology.
1999
Academic Article
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Times cited: 135 -
Exogenous control of cardiac gene therapy: evidence of regulated myocardial transgene expression after adenovirus and adeno-associated virus transfer of expression cassettes containing corticosteroid response element promoters.
The Journal of thoracic and cardiovascular surgery.
1999
Academic Article
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Times cited: 17 -
Expression and use of human immunodeficiency virus type 1 coreceptors by human alveolar macrophages.
Journal of virology.
1999
Academic Article
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Times cited: 50 -
Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors.
Journal of virology.
1999
Academic Article
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Times cited: 135 -
Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibrosis.
Journal of applied physiology (Bethesda, Md. : 1985).
1999
Academic Article
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Times cited: 103 -
Inhibition of tumor necrosis factor alpha by an adenovirus-encoded soluble fusion protein extends transgene expression in the liver and lung.
Journal of virology.
1999
Academic Article
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Times cited: 35 -
Anti-tumor immunity induced by in vivo adenovirus vector-mediated expression of CD40 ligand in tumor cells.
Human gene therapy.
1999
Academic Article
GET IT
Times cited: 81 -
Safety of direct myocardial administration of an adenovirus vector encoding vascular endothelial growth factor 121.
Human gene therapy.
1999
Academic Article
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Times cited: 47 -
Adenovirus-mediated expression of interleukin-12 induces natural killer cell activity and complements adenovirus-directed gp75 treatment of melanoma lung metastases.
American journal of respiratory cell and molecular biology.
1999
Academic Article
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Times cited: 14 -
E1(-)E4(+) adenoviral gene transfer vectors function as a "pro-life" signal to promote survival of primary human endothelial cells.
Blood.
1999
Academic Article
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Times cited: 32 -
Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor.
American journal of respiratory cell and molecular biology.
1999
Academic Article
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Times cited: 71 -
Use of L-plastin promoter to develop an adenoviral system that confers transgene expression in ovarian cancer cells but not in normal mesothelial cells.
Cancer gene therapy.
1999
Academic Article
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Times cited: 56 -
CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts.
The Journal of clinical investigation.
1999
Academic Article
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Times cited: 195 -
Therapeutic angiogenesis: protein and gene therapy delivery strategies.
Journal of cardiovascular risk.
1999
Information Resource
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Times cited: 46 -
Selective expansion of alveolar macrophages in vivo by adenovirus-mediated transfer of the murine granulocyte-macrophage colony-stimulating factor cDNA.
Blood.
1999
Academic Article
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Times cited: 37 -
Adenovirus vector-mediated perforin expression driven by a glucocorticoid-inducible promoter inhibits tumor growth in vivo.
American journal of respiratory cell and molecular biology.
1998
Academic Article
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Times cited: 8 -
Construction and characterization of hexon-chimeric adenoviruses: specification of adenovirus serotype.
Journal of virology.
1998
Academic Article
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Times cited: 90 -
[Adenovirus long-term expression of thrombopoietin in vivo: a new model for myeloproliferative syndrome and osteomyelofibrosis].
Schweizerische medizinische Wochenschrift.
1998
Academic Article
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Times cited: 13 -
Reversal of CPT-11 resistance of lung cancer cells by adenovirus-mediated gene transfer of the human carboxylesterase cDNA.
Cancer research.
1998
Academic Article
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Times cited: 37 -
Intermittent, repetitive corticosteroid-induced upregulation of platelet levels after adenovirus-mediated transfer to the liver of a chimeric glucocorticoid-responsive promoter controlling the thrombopoietin cDNA.
Blood.
1998
Academic Article
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Times cited: 12 -
Cytosine deaminase adenoviral vector and 5-fluorocytosine selectively reduce breast cancer cells 1 million-fold when they contaminate hematopoietic cells: a potential purging method for autologous transplantation.
Blood.
1998
Academic Article
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Times cited: 34 -
Adenovirus-mediated expression of melanoma antigen gp75 as immunotherapy for metastatic melanoma.
Gene therapy.
1998
Academic Article
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Times cited: 32 -
Gene therapy for oxidant injury-related diseases: adenovirus-mediated transfer of superoxide dismutase and catalase cDNAs protects against hyperoxia but not against ischemia-reperfusion lung injury.
Human gene therapy.
1998
Academic Article
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Times cited: 85 - Re: Gene therapy strategies for tumor antiangiogenesis. Journal of the National Cancer Institute. 1998 Article GET IT
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Survival and FEV1 decline in individuals with severe deficiency of alpha1-antitrypsin. The Alpha-1-Antitrypsin Deficiency Registry Study Group.
American journal of respiratory and critical care medicine.
1998
Academic Article
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Times cited: 398 -
Similarity of strain- and route-dependent murine responses to an adenovirus vector using the homologous thrombopoietin cDNA as the reporter genes.
Human gene therapy.
1998
Academic Article
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Times cited: 21 - Molecular therapy for cancer. The cancer journal from Scientific American. 1998 Academic Article GET IT
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High-efficiency gene transfer into ex vivo expanded human hematopoietic progenitors and precursor cells by adenovirus vectors.
Blood.
1998
Academic Article
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Times cited: 73 -
In vivo human carboxylesterase cDNA gene transfer to activate the prodrug CPT-11 for local treatment of solid tumors.
The Journal of clinical investigation.
1998
Academic Article
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Times cited: 74 -
Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor.
Human gene therapy.
1998
Academic Article
GET IT
Times cited: 172 -
Pulmonary cell biology.
American journal of respiratory and critical care medicine.
1998
Information Resource
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Times cited: 17 -
Regional 'pro-drug' gene therapy: intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma.
Gene therapy.
1998
Academic Article
GET IT
Times cited: 76 -
Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion.
Journal of vascular surgery.
1998
Academic Article
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Times cited: 127 -
Gene therapy strategies for tumor antiangiogenesis.
Journal of the National Cancer Institute.
1998
Information Resource
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Times cited: 165 -
Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells.
Human gene therapy.
1998
Academic Article
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Times cited: 205 -
Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: insights into the pathophysiology of osteomyelofibrosis.
Journal of immunology (Baltimore, Md. : 1950).
1998
Academic Article
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Times cited: 72 -
Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart.
The Journal of thoracic and cardiovascular surgery.
1998
Academic Article
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Times cited: 294 -
Pharmacological expression in rat hepatocytes of a gene transferred by an adenovirus vector enabled by a chimeric promoter containing multiple cyclic adenosine monophosphate response elements.
Hepatology (Baltimore, Md.).
1998
Academic Article
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Times cited: 7 -
Results of retroviral and adenoviral approaches to cancer gene therapy.
Stem cells (Dayton, Ohio).
1998
Information Resource
GET IT
Times cited: 20 -
The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro.
Gene therapy.
1998
Academic Article
GET IT
Times cited: 103 -
Human gene marker/therapy clinical protocols.
Human gene therapy.
1997
Academic Article
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Times cited: 23 -
Ability of a chimeric cAMP-responsive promoter to confer pharmacologic control of CFTR cDNA expression and cAMP-mediated Cl- secretion.
Gene therapy.
1997
Academic Article
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Times cited: 9 -
Construction of an adenovirus type 7a E1A- vector.
Journal of virology.
1997
Academic Article
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Times cited: 40 -
Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic antitumor immunity.
The Journal of experimental medicine.
1997
Academic Article
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Times cited: 359 -
Adenovirus-mediated gene transfer of fibroblast growth factor-1: angiogenesis and tumorigenicity in nude mice.
International journal of cancer.
1997
Academic Article
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Times cited: 7 -
Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract.
Human gene therapy.
1997
Academic Article
GET IT
Times cited: 115 -
Tumor necrosis factor alpha plays a central role in immune-mediated clearance of adenoviral vectors.
Proceedings of the National Academy of Sciences of the United States of America.
1997
Academic Article
GET IT
Times cited: 130 -
Inhibition of vascular smooth muscle cell proliferation and neointimal accumulation by adenovirus-mediated gene transfer of cytosine deaminase.
Circulation.
1997
Academic Article
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Times cited: 60 -
Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors.
Human gene therapy.
1997
Academic Article
GET IT
Times cited: 64 -
Adenoviral thymidine kinase prodrug gene therapy inhibits sarcoma growth in vivo.
The Journal of surgical research.
1997
Academic Article
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Times cited: 4 -
Augmentation of blood platelet levels by intratracheal administration of an adenovirus vector encoding human thrombopoietin cDNA.
Nature biotechnology.
1997
Academic Article
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Times cited: 19 -
Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine.
Human gene therapy.
1997
Academic Article
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Times cited: 120 - Quality control of spirometry testing in the registry for patients with severe alpha1-antitrypsin deficiency. alpha1-Antitrypsin Deficiency Registry Study Group. Chest. 1997 Academic Article GET IT
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alpha1-antitrypsin gene mutation hot spot associated with the formation of a retained and degraded null variant [corrected; erratum to be published].
American journal of respiratory cell and molecular biology.
1997
Academic Article
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Times cited: 27 -
Delayed-type hypersensitivity response to high doses of adenoviral vectors.
Human gene therapy.
1997
Academic Article
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Times cited: 12 -
Baseline characteristics of enrollees in the National Heart, Lung and Blood Institute Registry of alpha 1-antitrypsin deficiency. Alpha 1-Antitrypsin Deficiency Registry Study Group.
Chest.
1997
Academic Article
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Times cited: 174 -
Regional angiogenesis induced in nonischemic tissue by an adenoviral vector expressing vascular endothelial growth factor.
Human gene therapy.
1997
Academic Article
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Times cited: 79 -
Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype.
Human gene therapy.
1997
Academic Article
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Times cited: 171 -
Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ.
Journal of virology.
1997
Academic Article
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Times cited: 193 -
Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.
Human gene therapy.
1997
Academic Article
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Times cited: 413 -
Activated neutrophils secrete stored alpha 1-antitrypsin.
American journal of respiratory and critical care medicine.
1996
Academic Article
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Times cited: 40 -
Clinical features of individuals with PI*SZ phenotype of alpha 1-antitrypsin deficiency. alpha 1-Antitrypsin Deficiency Registry Study Group.
American journal of respiratory and critical care medicine.
1996
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Times cited: 144 -
Human gene marker/therapy clinical protocols.
Human gene therapy.
1996
Academic Article
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Times cited: 13 -
Transfer of a gene encoding the anticandidal protein histatin 3 to salivary glands.
Human gene therapy.
1996
Academic Article
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Times cited: 69 -
Superoxide-mediated actin response in post-hypoxic endothelial cells.
The Journal of biological chemistry.
1996
Academic Article
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Times cited: 79 -
Regulatable promoters for use in gene therapy applications: modification of the 5'-flanking region of the CFTR gene with multiple cAMP response elements to support basal, low-level gene expression that can be upregulated by exogenous agents that raise intracellular levels of cAMP.
Human gene therapy.
1996
Academic Article
GET IT
Times cited: 24 -
Human gene marker/therapy clinical protocols.
Human gene therapy.
1996
Academic Article
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Times cited: 13 -
Regional delivery of an adenovirus vector containing the Escherichia coli cytosine deaminase gene to provide local activation of 5-fluorocytosine to suppress the growth of colon carcinoma metastatic to liver.
Human gene therapy.
1996
Academic Article
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Times cited: 77 -
Direct in vivo gene transfer to canine myocardium using a replication-deficient adenovirus vector.
The Annals of thoracic surgery.
1996
Academic Article
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Times cited: 70 -
In vivo adenovirus vector-mediated transfer of the human thrombopoietin cDNA maintains platelet levels during radiation-and chemotherapy-induced bone marrow suppression.
Blood.
1996
Academic Article
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Times cited: 47 -
Limited heterogeneity of biased T-cell receptor V beta gene usage in lung but not blood T cells in active pulmonary sarcoidosis.
Immunology.
1996
Academic Article
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Times cited: 41 -
In vivo replication-deficient adenovirus vector-mediated transduction of the cytosine deaminase gene sensitizes glioma cells to 5-fluorocytosine.
Human gene therapy.
1996
Academic Article
GET IT
Times cited: 79 -
Ectopic expression of thyrotropin releasing hormone (TRH) receptors in liver modulates organ function to regulate blood glucose by TRH.
Nature genetics.
1996
Academic Article
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Times cited: 7 -
Uptake of fluorescent dyes associated with the functional expression of the cystic fibrosis transmembrane conductance regulator in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America.
1996
Academic Article
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Times cited: 19 -
Safety and efficacy of in vivo gene transfer into the porcine heart with replication-deficient, recombinant adenovirus vectors.
Gene therapy.
1996
Academic Article
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Times cited: 112 -
"Sero-switch" adenovirus-mediated in vivo gene transfer: circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype.
Human gene therapy.
1996
Academic Article
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Times cited: 180 -
Quantitative assessment of the epithelial and inflammatory cell populations in large airways of normals and individuals with cystic fibrosis.
American journal of respiratory and critical care medicine.
1996
Academic Article
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Times cited: 58 -
Adenovirus-mediated gene transfer of dopamine D2 receptor cDNA into rat striatum.
Brain research. Molecular brain research.
1995
Academic Article
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Times cited: 33 -
Retrograde transfer of replication deficient recombinant adenovirus vector in the central nervous system for tracing studies.
Brain research.
1995
Academic Article
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Times cited: 50 -
VEGF165 expressed by a replication-deficient recombinant adenovirus vector induces angiogenesis in vivo.
Circulation research.
1995
Academic Article
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Times cited: 146 -
In vivo angiogenesis induced by recombinant adenovirus vectors coding either for secreted or nonsecreted forms of acidic fibroblast growth factor.
Human gene therapy.
1995
Academic Article
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Times cited: 66 -
Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector.
Human gene therapy.
1995
Academic Article
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Times cited: 119 -
In vivo adenovirus-mediated gene transfer of the Escherichia coli cytosine deaminase gene to human colon carcinoma-derived tumors induces chemosensitivity to 5-fluorocytosine.
Human gene therapy.
1995
Academic Article
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Times cited: 184 -
Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis.
Human gene therapy.
1995
Academic Article
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Times cited: 32 -
Human CC10 gene expression in airway epithelium and subchromosomal locus suggest linkage to airway disease.
The American journal of physiology.
1995
Academic Article
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Times cited: 68 -
Polarity of secretion of alpha 1-antitrypsin by human respiratory epithelial cells after adenoviral transfer of a human alpha 1-antitrypsin cDNA.
American journal of respiratory cell and molecular biology.
1995
Academic Article
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Times cited: 22 -
IL-6 release and airway administration of human CFR cDNA adenovirus vector.
Nature medicine.
1995
Article
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Times cited: 66 -
In vitro and in vivo transfer and expression of human surfactant SP-A- and SP-B-associated protein cDNAs mediated by replication-deficient, recombinant adenoviral vectors.
Human gene therapy.
1995
Academic Article
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Times cited: 61 -
Modulation of gene expression after replication-deficient, recombinant adenovirus-mediated gene transfer by the product of a second adenovirus vector.
Gene therapy.
1995
Academic Article
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Times cited: 132 -
Identification of a 27 bp 5'-flanking region element responsible for the low level constitutive expression of the human cytosolic phospholipase A2 gene.
Nucleic acids research.
1995
Academic Article
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Times cited: 60 -
Stimulation of erythropoiesis by in vivo gene therapy: physiologic consequences of transfer of the human erythropoietin gene to experimental animals using an adenovirus vector.
Blood.
1994
Academic Article
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Times cited: 72 -
In vivo suppression of injury-induced vascular smooth muscle cell accumulation using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene.
Proceedings of the National Academy of Sciences of the United States of America.
1994
Academic Article
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Times cited: 180 -
Transfer of a constitutive viral promoter-cystic fibrosis transmembrane conductance regulator cDNA to human epithelial cells conveys resistance to down-regulation of cAMP-regulated Cl- secretion in the presence of inflammatory stimuli.
Nucleic acids research.
1994
Academic Article
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Times cited: 3 - Enhancer function of a 53-bp repetitive element in the 5' flanking region of the human neutrophil elastase gene. Biochemical and biophysical research communications. 1994 Academic Article GET IT
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A registry of patients with severe deficiency of alpha 1-antitrypsin. Design and methods. The Alpha 1-Antitrypsin Deficiency Registry Study Group.
Chest.
1994
Academic Article
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Times cited: 47 -
Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis.
Nature genetics.
1994
Academic Article
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Times cited: 764 -
Evaluation of the respiratory epithelium of normals and individuals with cystic fibrosis for the presence of adenovirus E1a sequences relevant to the use of E1a- adenovirus vectors for gene therapy for the respiratory manifestations of cystic fibrosis.
Human gene therapy.
1994
Academic Article
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Times cited: 34 -
Increasing expression of the normal human CFTR cDNA in cystic fibrosis epithelial cells results in a progressive increase in the level of CFTR protein expression, but a limit on the level of cAMP-stimulated chloride secretion.
Human gene therapy.
1994
Academic Article
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Times cited: 12 -
Suppression of in vivo tumorigenicity of human lung cancer cells by retrovirus-mediated transfer of the human tumor necrosis factor-alpha cDNA.
American journal of respiratory cell and molecular biology.
1994
Academic Article
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Times cited: 28 -
Acute responses of non-human primates to airway delivery of an adenovirus vector containing the human cystic fibrosis transmembrane conductance regulator cDNA.
Human gene therapy.
1994
Academic Article
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Times cited: 138 -
Modulation of secretory leukoprotease inhibitor gene expression in human bronchial epithelial cells by phorbol ester.
The Journal of clinical investigation.
1994
Academic Article
GET IT
Times cited: 54 -
Protease-antiprotease imbalance in the lungs of children with cystic fibrosis.
American journal of respiratory and critical care medicine.
1994
Academic Article
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Times cited: 324 -
Adenovirus-mediated transfer of human lipase complementary DNA to the gallbladder.
Gastroenterology.
1994
Academic Article
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Times cited: 41 -
Direct in vivo adenovirus-mediated gene transfer to salivary glands.
The American journal of physiology.
1994
Academic Article
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Times cited: 120 -
In vivo adenovirus-mediated gene transfer to lungs via pulmonary artery.
Journal of applied physiology (Bethesda, Md. : 1985).
1994
Academic Article
GET IT
Times cited: 47 -
Direct in vivo gene transfer and expression in malignant cells using adenovirus vectors.
Human gene therapy.
1994
Academic Article
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Times cited: 58 -
Ex vivo and in vivo gene transfer to the skin using replication-deficient recombinant adenovirus vectors.
The Journal of investigative dermatology.
1994
Academic Article
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Times cited: 94 -
Intraperitoneal in vivo gene therapy to deliver alpha 1-antitrypsin to the systemic circulation.
American journal of respiratory cell and molecular biology.
1994
Academic Article
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Times cited: 93 -
Gene transfer to freshly isolated human respiratory epithelial cells in vitro using a replication-deficient adenovirus containing the human cystic fibrosis transmembrane conductance regulator cDNA.
Human gene therapy.
1994
Academic Article
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Times cited: 48 -
Mechanism of enhancement of DNA expression consequent to cointernalization of a replication-deficient adenovirus and unmodified plasmid DNA.
Journal of virology.
1994
Academic Article
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Times cited: 61 -
Vulnerability of the human airway epithelium to hyperoxia. Constitutive expression of the catalase gene in human bronchial epithelial cells despite oxidant stress.
The Journal of clinical investigation.
1994
Academic Article
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Times cited: 50 -
Efficient and selective adenovirus-mediated gene transfer into vascular neointima.
Circulation.
1993
Academic Article
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Times cited: 154 -
Efficient gene transfer into myocardium by direct injection of adenovirus vectors.
Circulation research.
1993
Academic Article
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Times cited: 218 -
Systemic deficiency of glutathione in cystic fibrosis.
Journal of applied physiology (Bethesda, Md. : 1985).
1993
Academic Article
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Times cited: 331 -
A mutation in CFTR produces different phenotypes depending on chromosomal background.
Nature genetics.
1993
Academic Article
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Times cited: 341 -
Correction of glutathione deficiency in the lower respiratory tract of HIV seropositive individuals by glutathione aerosol treatment.
Thorax.
1993
Academic Article
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Times cited: 42 -
Gene therapy for pulmonary diseases.
Pathologie-biologie.
1993
Information Resource
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Times cited: 15 -
Pharmacokinetics of recombinant secretory leukoprotease inhibitor aerosolized to normals and individuals with cystic fibrosis.
The American review of respiratory disease.
1993
Academic Article
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Times cited: 104 -
Pulmonary Langerhans cell granulomatosis (histiocytosis X). A clinicopathologic study of 48 cases.
The American journal of surgical pathology.
1993
Academic Article
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Times cited: 259 -
Aerosolization of superoxide dismutase. Augmentation of respiratory epithelial lining fluid antioxidant screen by aerosolization of recombinant human Cu++/Zn++ superoxide dismutase.
Chest.
1993
Academic Article
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Times cited: 30 -
In vivo antioxidant gene expression in human airway epithelium of normal individuals exposed to 100% O2.
Journal of applied physiology (Bethesda, Md. : 1985).
1993
Academic Article
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Times cited: 68 -
Recombinant secretory leukoprotease inhibitor augments glutathione levels in lung epithelial lining fluid.
Journal of applied physiology (Bethesda, Md. : 1985).
1993
Academic Article
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Times cited: 56 -
In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors.
Circulation research.
1993
Academic Article
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Times cited: 245 -
Protection of human endothelial cells from oxidant injury by adenovirus-mediated transfer of the human catalase cDNA.
Nucleic acids research.
1993
Academic Article
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Times cited: 103 -
Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors.
Nature genetics.
1993
Academic Article
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Times cited: 326 -
Adenovirus-mediated augmentation of cell transfection with unmodified plasmid vectors.
The Journal of biological chemistry.
1993
Academic Article
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Times cited: 92 -
Activation of alveolar macrophages in asymptomatic HIV-infected individuals.
Journal of immunology (Baltimore, Md. : 1950).
1993
Academic Article
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Times cited: 79 -
Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA.
Nature genetics.
1993
Academic Article
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Times cited: 423 -
Alternative splicing of intron 23 of the human cystic fibrosis transmembrane conductance regulator gene resulting in a novel exon and transcript coding for a shortened intracytoplasmic C terminus.
The Journal of biological chemistry.
1993
Academic Article
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Times cited: 20 -
Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer.
The Journal of clinical investigation.
1993
Academic Article
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Times cited: 201 -
Tumor necrosis factor modulation of expression of the cystic fibrosis transmembrane conductance regulator gene.
FEBS letters.
1992
Academic Article
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Times cited: 41 -
Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor.
The Journal of clinical investigation.
1992
Academic Article
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Times cited: 267 -
Extensive posttranscriptional deletion of the coding sequences for part of nucleotide-binding fold 1 in respiratory epithelial mRNA transcripts of the cystic fibrosis transmembrane conductance regulator gene is not associated with the clinical manifestations of cystic fibrosis.
The Journal of clinical investigation.
1992
Academic Article
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Times cited: 111 -
Aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis.
The New England journal of medicine.
1992
Article
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Times cited: 7 -
Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.
The Journal of biological chemistry.
1992
Academic Article
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Times cited: 29 -
Adenovirus-mediated in vivo gene transfer and expression in normal rat liver.
Nature genetics.
1992
Academic Article
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Times cited: 414 -
Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America.
1992
Academic Article
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Times cited: 187 -
Intravenous recombinant secretory leukoprotease inhibitor augments antineutrophil elastase defense.
Journal of applied physiology (Bethesda, Md. : 1985).
1992
Academic Article
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Times cited: 24 -
Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer.
Nucleic acids research.
1992
Academic Article
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Times cited: 184 -
Transcriptional and posttranscriptional modulation of human neutrophil elastase gene expression.
Blood.
1992
Academic Article
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Times cited: 25 -
Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line.
The Journal of clinical investigation.
1992
Academic Article
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Times cited: 445 -
T-lymphocytes that accumulate in the lung in sarcoidosis have evidence of recent stimulation of the T-cell antigen receptor.
The American review of respiratory disease.
1992
Academic Article
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Times cited: 76 -
The promoter of the human cystic fibrosis transmembrane conductance regulator gene directing SV40 T antigen expression induces malignant proliferation of ependymal cells in transgenic mice.
Oncogene.
1992
Academic Article
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Times cited: 10 -
Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations.
Molecular and cellular biology.
1992
Academic Article
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Times cited: 36 -
A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis.
The New England journal of medicine.
1992
Academic Article
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Times cited: 163 -
Endothelial fenestration of the alveolar capillaries in interstitial fibrotic lung diseases.
Acta pathologica japonica.
1992
Academic Article
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Times cited: 24 -
In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium.
Cell.
1992
Academic Article
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Times cited: 840 -
Cystic fibrosis transmembrane conductance regulator (CFTR) gene transcripts.
The EMBO journal.
1992
Article
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Times cited: 5 -
Altered chloride ion channel kinetics associated with the delta F508 cystic fibrosis mutation.
Nature.
1991
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Times cited: 524 -
Severe deficiency of cystic fibrosis transmembrane conductance regulator messenger RNA carrying nonsense mutations R553X and W1316X in respiratory epithelial cells of patients with cystic fibrosis.
The Journal of clinical investigation.
1991
Academic Article
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Times cited: 129 -
Augmentation of functional prostaglandin E levels on the respiratory epithelial surface by aerosol administration of prostaglandin E.
The American review of respiratory disease.
1991
Academic Article
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Times cited: 116 -
Interleukin-8 gene expression in human bronchial epithelial cells.
The Journal of biological chemistry.
1991
Academic Article
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Times cited: 222 -
Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin.
Nucleic acids research.
1991
Academic Article
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Times cited: 149 -
Respiratory tract gene transfer. Transplantation of genetically modified T-lymphocytes directly to the respiratory epithelial surface.
The Journal of biological chemistry.
1991
Academic Article
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Times cited: 12 -
Alpha 1-antitrypsin is present within the primary granules of human polymorphonuclear leukocytes.
The American journal of pathology.
1991
Academic Article
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Times cited: 40 -
Neutrophil accumulation in the lung in alpha 1-antitrypsin deficiency. Spontaneous release of leukotriene B4 by alveolar macrophages.
The Journal of clinical investigation.
1991
Academic Article
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Times cited: 195 -
Use of a highly purified alpha 1-antitrypsin standard to establish ranges for the common normal and deficient alpha 1-antitrypsin phenotypes.
Chest.
1991
Academic Article
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Times cited: 133 -
Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis.
Proceedings of the National Academy of Sciences of the United States of America.
1991
Academic Article
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Times cited: 224 -
Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis.
Lancet (London, England).
1991
Academic Article
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Times cited: 170 -
Organ specific cytokine therapy. Local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-gamma to the human lung.
The Journal of clinical investigation.
1991
Academic Article
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Times cited: 132 -
Human neutrophils express the alpha 1-antitrypsin gene and produce alpha 1-antitrypsin.
Blood.
1991
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Times cited: 70 -
Down-regulation of cystic fibrosis gene mRNA transcript levels and induction of the cystic fibrosis chloride secretory phenotype in epithelial cells by phorbol ester.
The Journal of biological chemistry.
1991
Academic Article
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Times cited: 72 -
Characterization of the molecular basis of the alpha 1-antitrypsin F allele.
American journal of human genetics.
1991
Academic Article
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Times cited: 26 -
Expression of the secretory leukoprotease inhibitor gene in epithelial cells.
The Journal of clinical investigation.
1991
Academic Article
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Times cited: 133 -
Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium.
The EMBO journal.
1991
Academic Article
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Times cited: 149 -
The cystic fibrosis gene has a "housekeeping"-type promoter and is expressed at low levels in cells of epithelial origin.
The Journal of biological chemistry.
1991
Academic Article
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Times cited: 138 -
Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo.
Science (New York, N.Y.).
1991
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Times cited: 649 -
Preferential usage of the T-cell antigen receptor beta-chain constant region C beta 1 element by lung T-lymphocytes of patients with pulmonary sarcoidosis.
The American review of respiratory disease.
1991
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Times cited: 25 -
Risk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase.
The Journal of clinical investigation.
1991
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Times cited: 84 -
Aerosol alpha 1-antitrypsin treatment for cystic fibrosis.
Lancet (London, England).
1991
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Times cited: 294 -
Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor.
The Journal of clinical investigation.
1991
Academic Article
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Times cited: 166 -
Aerosolization of recombinant SLPI to augment antineutrophil elastase protection of pulmonary epithelium.
Journal of applied physiology (Bethesda, Md. : 1985).
1990
Academic Article
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Times cited: 55 -
Molecular analysis of the heterogeneity among the P-family of alpha-1-antitrypsin alleles.
The American review of respiratory disease.
1990
Academic Article
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Times cited: 24 -
Persistent lower respiratory tract inflammation associated with interstitial lung disease in patients with tropical pulmonary eosinophilia following conventional treatment with diethylcarbamazine.
The American review of respiratory disease.
1990
Academic Article
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Times cited: 46 -
Alpha 1-antitrypsin Null(isola di procida): an alpha 1-antitrypsin deficiency allele caused by deletion of all alpha 1-antitrypsin coding exons.
American journal of human genetics.
1990
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Times cited: 40 -
Antioxidant macromolecules in the epithelial lining fluid of the normal human lower respiratory tract.
The Journal of clinical investigation.
1990
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Times cited: 116 -
Alpha 1-antitrypsin Wbethesda: molecular basis of an unusual alpha 1-antitrypsin deficiency variant.
Biochemical and biophysical research communications.
1990
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Times cited: 16 -
Intraluminal fibrosis and elastic fiber degradation lead to lung remodeling in pulmonary Langerhans cell granulomatosis (histiocytosis X).
The American journal of pathology.
1990
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Diversity in junctional sequences associated with the common human V gamma 9 and V delta 2 gene segments in normal blood and lung compared with the limited diversity in a granulomatous disease.
The Journal of experimental medicine.
1990
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Times cited: 93 -
Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol.
Proceedings of the National Academy of Sciences of the United States of America.
1990
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Upregulation of platelet-derived growth factor-A and -B gene expression in alveolar macrophages of individuals with idiopathic pulmonary fibrosis.
The Journal of clinical investigation.
1990
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Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy.
The Journal of clinical investigation.
1990
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Increased numbers of T lymphocytes with gamma delta-positive antigen receptors in a subgroup of individuals with pulmonary sarcoidosis.
The Journal of clinical investigation.
1990
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Times cited: 100 -
Biased accumulation of T lymphocytes with "memory"-type CD45 leukocyte common antigen gene expression on the epithelial surface of the human lung.
The Journal of experimental medicine.
1990
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Times cited: 139 -
Characterization of the normal alpha 1-antitrypsin allele Vmunich: a variant associated with a unique protein isoelectric focusing pattern.
American journal of human genetics.
1990
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Times cited: 10 -
Glutathione deficiency and HIV.
Lancet (London, England).
1990
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Regulation of insulin-like growth factor I gene expression in the human macrophage-like cell line U937.
The Journal of clinical investigation.
1990
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Molecular basis of alpha 1-antitrypsin deficiency and emphysema associated with the alpha 1-antitrypsin Mmineral springs allele.
Molecular and cellular biology.
1990
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Strategies for aerosol therapy of alpha 1-antitrypsin deficiency by the aerosol route.
Lung.
1990
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Systemic glutathione deficiency in symptom-free HIV-seropositive individuals.
Lancet (London, England).
1989
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Characterization of the intracellular mechanism causing the alpha-1-antitrypsin Nullgranite falls deficiency state.
The American review of respiratory disease.
1989
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Times cited: 11 -
Characterization of the sequence of the normal alpha-1-antitrypsin M3 allele and function of the M3 protein.
American journal of respiratory cell and molecular biology.
1989
Academic Article
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Times cited: 3 -
Morphologic characterization of alveolar macrophages from subjects with occupational exposure to inorganic particles.
The American review of respiratory disease.
1989
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Tropical pulmonary eosinophilia: analysis of antifilarial antibody localized to the lung.
The Journal of infectious diseases.
1989
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Guidelines for the approach to the patient with severe hereditary alpha-1-antitrypsin deficiency. American Thoracic Society.
The American review of respiratory disease.
1989
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Recombinant DNA-produced alpha 1-antitrypsin administered by aerosol augments lower respiratory tract antineutrophil elastase defenses in individuals with alpha 1-antitrypsin deficiency.
The Journal of clinical investigation.
1989
Academic Article
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Times cited: 100 -
Ribonuclease A cleavage combined with the polymerase chain reaction for detection of the Z mutation of the alpha-1-antitrypsin gene.
American journal of respiratory cell and molecular biology.
1989
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Times cited: 4 -
Characterization of the coding sequence of the normal M4 alpha 1-antitrypsin gene.
Biochemical and biophysical research communications.
1989
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Anti-neutrophil-elastase defenses of the lower respiratory tract in alpha 1-antitrypsin deficiency directly augmented with an aerosol of alpha 1-antitrypsin.
Annals of internal medicine.
1989
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Rapid, nonradioactive detection of mutations in the human genome by allele-specific amplification.
The Journal of laboratory and clinical medicine.
1989
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Expression of HLA class II genes in alveolar macrophages of patients with sarcoidosis.
The American review of respiratory disease.
1989
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Serum alpha 1-antitrypsin deficiency associated with the common S-type (Glu264----Val) mutation results from intracellular degradation of alpha 1-antitrypsin prior to secretion.
The Journal of biological chemistry.
1989
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Maintenance of alveolitis in patients with chronic beryllium disease by beryllium-specific helper T cells.
The New England journal of medicine.
1989
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Expression of the neutrophil elastase gene during human bone marrow cell differentiation.
The Journal of experimental medicine.
1989
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A Pro----Leu substitution in codon 369 of the alpha-1-antitrypsin deficiency variant PI MHeerlen.
Human genetics.
1989
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Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis.
The American review of respiratory disease.
1989
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Fate of aerosolized recombinant DNA-produced alpha 1-antitrypsin: use of the epithelial surface of the lower respiratory tract to administer proteins of therapeutic importance.
Proceedings of the National Academy of Sciences of the United States of America.
1989
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Repair of the secretion defect in the Z form of alpha 1-antitrypsin by addition of a second mutation.
Science (New York, N.Y.).
1988
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Alveolar macrophages release an insulin-like growth factor I-type molecule.
The Journal of clinical investigation.
1988
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Evaluation of fibronectin gene expression by in situ hybridization. Differential expression of the fibronectin gene among populations of human alveolar macrophages.
The American journal of pathology.
1988
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Evaluation of the in vitro and in vivo effects of cyclosporine on the lung T-lymphocyte alveolitis of active pulmonary sarcoidosis.
The American review of respiratory disease.
1988
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Characterization of the gene and protein of the alpha 1-antitrypsin "deficiency" allele Mprocida.
The Journal of biological chemistry.
1988
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Structure of the human neutrophil elastase gene.
The Journal of biological chemistry.
1988
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Bias toward use of a specific T cell receptor beta-chain variable region in a subgroup of individuals with sarcoidosis.
The Journal of clinical investigation.
1988
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Molecular genetics in pulmonary emphysema.
The American review of respiratory disease.
1988
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Cloning and characterization of an alpha 1-antitrypsin like gene 12 KB downstream of the genuine alpha 1-antitrypsin gene.
Biochemical and biophysical research communications.
1988
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Biochemical efficacy and safety of monthly augmentation therapy for alpha 1-antitrypsin deficiency.
JAMA.
1988
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Characterization of the gene and protein of the common alpha 1-antitrypsin normal M2 allele.
American journal of human genetics.
1988
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Differential expression of the tumor necrosis factor/cachectin gene by blood and lung mononuclear phagocytes.
The American review of respiratory disease.
1988
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Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 receptors on T lymphocytes in the blood of individuals with active pulmonary sarcoidosis.
The Journal of clinical investigation.
1988
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Clinical features and history of the destructive lung disease associated with alpha-1-antitrypsin deficiency of adults with pulmonary symptoms.
The American review of respiratory disease.
1988
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Demonstration by in situ hybridization of dissimilar IL-1 beta gene expression in human alveolar macrophages and blood monocytes in response to lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950).
1988
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High levels of transforming growth factor-beta are present in the epithelial lining fluid of the normal human lower respiratory tract.
The American review of respiratory disease.
1988
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Sarcoidosis is not associated with a generalized defect in T cell suppressor function.
Journal of immunology (Baltimore, Md. : 1950).
1988
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Functional significance of anti-T-lymphocyte antibodies in sarcoidosis.
The American review of respiratory disease.
1988
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GET IT
Times cited: 1 -
Myelomonocytic cell lineage expression of the neutrophil elastase gene.
The Journal of biological chemistry.
1988
Academic Article
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Times cited: 83 -
Accumulation of Langerhans' cells on the epithelial surface of the lower respiratory tract in normal subjects in association with cigarette smoking.
The American review of respiratory disease.
1988
Academic Article
GET IT
Times cited: 151 -
Evaluation of the S-type of alpha-1-antitrypsin as an in vivo and in vitro inhibitor of neutrophil elastase.
The American review of respiratory disease.
1988
Academic Article
GET IT
Times cited: 31 -
T lymphocytes compartmentalized on the epithelial surface of the lower respiratory tract express the very late activation antigen complex VLA-1.
Clinical immunology and immunopathology.
1988
Academic Article
GET IT
Times cited: 61 -
Colchicine suppresses the release of fibroblast growth factors from alveolar macrophages in vitro. The basis of a possible therapeutic approach ot the fibrotic disorders.
The American review of respiratory disease.
1988
Academic Article
GET IT
Times cited: 70 -
Does de novo immunoglobulin synthesis occur on the epithelial surface of the human lower respiratory tract?.
The American review of respiratory disease.
1988
Academic Article
GET IT
Times cited: 14 -
Characterization of the lower respiratory tract inflammation of nonsmoking individuals with interstitial lung disease associated with chronic inhalation of inorganic dusts.
The American review of respiratory disease.
1987
Academic Article
GET IT
Times cited: 169 -
Modulation of fibronectin gene expression in human mononuclear phagocytes.
The Journal of clinical investigation.
1987
Academic Article
GET IT
Times cited: 39 -
Augmentation of lung antineutrophil elastase capacity with recombinant human alpha-1-antitrypsin.
Journal of applied physiology (Bethesda, Md. : 1985).
1987
Academic Article
GET IT
Times cited: 55 -
Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase.
The Journal of clinical investigation.
1987
Academic Article
GET IT
Times cited: 134 -
Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase.
The Journal of clinical investigation.
1987
Academic Article
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Times cited: 175 -
alpha 1-Antitrypsin nullGranite Falls, a nonexpressing alpha 1-antitrypsin gene associated with a frameshift to stop mutation in a coding exon.
The Journal of biological chemistry.
1987
Academic Article
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Times cited: 48 -
Characterization of the M1(Ala213) type of alpha 1-antitrypsin, a newly recognized, common "normal" alpha 1-antitrypsin haplotype.
Biochemistry.
1987
Academic Article
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Times cited: 37 -
Clonal gene therapy: transplanted mouse fibroblast clones express human alpha 1-antitrypsin gene in vivo.
Science (New York, N.Y.).
1987
Academic Article
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Times cited: 87 -
Corticosteroid therapy suppresses spontaneous interleukin 2 release and spontaneous proliferation of lung T lymphocytes of patients with active pulmonary sarcoidosis.
Journal of immunology (Baltimore, Md. : 1950).
1987
Academic Article
GET IT
Times cited: 63 -
Mechanisms of macrophage accumulation in the lungs of asbestos-exposed subjects.
The American review of respiratory disease.
1987
Academic Article
GET IT
Times cited: 36 -
Pharmacologic suppression of the neutrophil component of the alveolitis in idiopathic pulmonary fibrosis.
The American review of respiratory disease.
1987
Academic Article
GET IT
Times cited: 48 - Exaggerated spontaneous release of platelet-derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosis. The New England journal of medicine. 1987 Academic Article GET IT
-
Evaluation of alveolar macrophages in normals and individuals with active pulmonary sarcoidosis for the spontaneous expression of the interleukin-1 beta gene.
Cellular immunology.
1987
Academic Article
GET IT
Times cited: 20 -
Normal alveolar epithelial lining fluid contains high levels of glutathione.
Journal of applied physiology (Bethesda, Md. : 1985).
1987
Academic Article
GET IT
Times cited: 665 - Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis. The Journal of clinical investigation. 1987 Academic Article GET IT
- Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema. The New England journal of medicine. 1987 Academic Article GET IT
-
Evaluation of tamoxifen as a therapy to augment alpha-1-antitrypsin concentrations in Z homozygous alpha-1-antitrypsin-deficient subjects.
The American review of respiratory disease.
1987
Academic Article
GET IT
Times cited: 22 -
Production of glycosylated physiologically "normal" human alpha 1-antitrypsin by mouse fibroblasts modified by insertion of a human alpha 1-antitrypsin cDNA using a retroviral vector.
Proceedings of the National Academy of Sciences of the United States of America.
1987
Academic Article
GET IT
Times cited: 51 -
Susceptibility to experimental interstitial lung disease is modified by immune- and non-immune-related genes.
The American review of respiratory disease.
1987
Academic Article
GET IT
Times cited: 62 -
Clonal gene therapy: in vivo expression of a transplanted monoclonal population of murine fibroblasts containing a retrovirus inserted human alpha 1-antitrypsin gene.
Transactions of the Association of American Physicians.
1987
Academic Article
GET IT
Times cited: 3 -
Cyclooxygenase metabolites are compartmentalized in the human lower respiratory tract.
Journal of applied physiology (Bethesda, Md. : 1985).
1987
Academic Article
GET IT
Times cited: 41 -
Identification of a second mutation in the protein-coding sequence of the Z type alpha 1-antitrypsin gene.
The Journal of biological chemistry.
1986
Academic Article
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Times cited: 79 -
Compartmentalized activation of the interleukin 2 gene by lung T lymphocytes in active pulmonary sarcoidosis.
Journal of immunology (Baltimore, Md. : 1950).
1986
Academic Article
GET IT
Times cited: 104 -
RNA structural elements for expression in Escherichia coli. Alpha 1-antitrypsin synthesis using translation control elements based on the cII ribosome-binding site of phage lambda.
FEBS letters.
1986
Academic Article
GET IT
Times cited: 15 -
Altered specificities of genetically engineered alpha 1 antitrypsin variants.
Protein engineering.
1986
Academic Article
GET IT
Times cited: 51 -
Antiprotease targeting: altered specificity of alpha 1-antitrypsin by amino acid replacement at the reactive centre.
Revue francaise de transfusion et immuno-hematologie.
1986
Academic Article
GET IT
Times cited: 2 -
Evaluation of danazol therapy for patients with PiZZ alpha-1-antitrypsin deficiency.
The American review of respiratory disease.
1986
Academic Article
GET IT
Times cited: 36 -
Bronchoalveolar lavage. The report of an international conference.
Chest.
1986
Academic Article
GET IT
Times cited: 78 - Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages. The Journal of clinical investigation. 1986 Academic Article GET IT
- Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individuals. The Journal of clinical investigation. 1986 Academic Article GET IT
- Spontaneous release of interleukin 2 by lung T lymphocytes in active pulmonary sarcoidosis is primarily from the Leu3+DR+ T cell subset. The Journal of clinical investigation. 1986 Academic Article GET IT
-
Human type III collagen gene expression is coordinately modulated with the type I collagen genes during fibroblast growth.
Biochemistry.
1986
Academic Article
GET IT
Times cited: 88 -
Intraluminal fibrosis in interstitial lung disorders.
The American journal of pathology.
1986
Academic Article
GET IT
Times cited: 227 - Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators. The Journal of clinical investigation. 1986 Academic Article GET IT
-
Expression of the transferrin receptor gene during the process of mononuclear phagocyte maturation.
Journal of immunology (Baltimore, Md. : 1950).
1986
Academic Article
GET IT
Times cited: 71 -
Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution.
Journal of applied physiology (Bethesda, Md. : 1985).
1986
Academic Article
GET IT
Times cited: 849 - Evaluation of "at risk" alpha 1-antitrypsin genotype SZ with synthetic oligonucleotide gene probes. The Journal of clinical investigation. 1986 Academic Article GET IT
-
Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity.
Nature.
1986
Academic Article
GET IT
Times cited: 234 -
Urinary excretion of desmosine (elastin cross-links) in subjects with PiZZ alpha-1-antitrypsin deficiency, a phenotype associated with hereditary predisposition to pulmonary emphysema.
The American review of respiratory disease.
1985
Academic Article
GET IT
Times cited: 37 -
Evaluation of recombinant DNA-directed E.coli produced alpha 1-antitrypsin as an anti-neutrophil elastase for potential use as replacement therapy of alpha 1-antitrypsin deficiency.
Biochemical and biophysical research communications.
1985
Academic Article
GET IT
Times cited: 27 -
Gamma interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis.
The Journal of clinical investigation.
1985
Academic Article
GET IT
Times cited: 390 -
Evidence for chronic inflammation as a component of the interstitial lung disease associated with progressive systemic sclerosis.
The American review of respiratory disease.
1985
Academic Article
GET IT
Times cited: 94 -
Patterns of pulmonary structural remodeling after experimental paraquat toxicity. The morphogenesis of intraalveolar fibrosis.
The American journal of pathology.
1985
Academic Article
GET IT
Times cited: 158 -
"Interstitial pathology': an overview of the chronic interstitial lung disorders.
International archives of allergy and applied immunology.
1985
Academic Article
GET IT
Times cited: 12 -
Characterization of mononuclear phagocyte subpopulations in the human lung by using monoclonal antibodies: changes in alveolar macrophage phenotype associated with pulmonary sarcoidosis.
Journal of immunology (Baltimore, Md. : 1950).
1985
Academic Article
GET IT
Times cited: 96 - Enhanced alveolar macrophage-mediated antigen-induced T-lymphocyte proliferation in sarcoidosis. The Journal of clinical investigation. 1985 Academic Article GET IT
-
Experimental polymyxin B-induced interstitial lung disease characterized by an accumulation of cytotoxic eosinophils in the alveolar structures.
The American review of respiratory disease.
1985
Academic Article
GET IT
Times cited: 21 -
Motheaten mice--an animal model with an inherited form of interstitial lung disease.
The American review of respiratory disease.
1985
Academic Article
GET IT
Times cited: 29 -
Pulmonary sarcoidosis: pathogenesis, staging and therapy.
International archives of allergy and applied immunology.
1985
Academic Article
GET IT
Times cited: 6 -
Synthesis in E. coli of alpha 1-antitrypsin variants of therapeutic potential for emphysema and thrombosis.
Nature.
1985
Academic Article
GET IT
Times cited: 89 - Normal human alveolar macrophages obtained by bronchoalveolar lavage have a limited capacity to release interleukin-1. The Journal of clinical investigation. 1984 Academic Article GET IT
-
Accurate quantification of cells recovered by bronchoalveolar lavage.
The American review of respiratory disease.
1984
Academic Article
GET IT
Times cited: 137 -
Alveolar macrophages in idiopathic pulmonary fibrosis have glucocorticoid receptors, but glucocorticoid therapy does not suppress alveolar macrophage release of fibronectin and alveolar macrophage derived growth factor.
The American review of respiratory disease.
1984
Academic Article
GET IT
Times cited: 30 -
Natural killer cells are present in the normal human lung but are functionally impotent.
The Journal of clinical investigation.
1984
Academic Article
GET IT
Times cited: 103 -
Pathogenesis of the granulomatous lung diseases.
The American review of respiratory disease.
1984
Information Resource
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Times cited: 108 - Alveolar macrophage replication. One mechanism for the expansion of the mononuclear phagocyte population in the chronically inflamed lung. The Journal of clinical investigation. 1984 Academic Article GET IT
-
Development of elastic fibers of nuchal ligament, aorta, and lung of fetal and postnatal sheep: an ultrastructural and electron microscopic immunohistochemical study.
The American journal of anatomy.
1984
Academic Article
GET IT
Times cited: 48 -
Role of pleural mesothelial cells in the production of the submesothelial connective tissue matrix of lung.
The American review of respiratory disease.
1984
Academic Article
GET IT
Times cited: 94 - Eosinophil-mediated injury to lung parenchymal cells and interstitial matrix. A possible role for eosinophils in chronic inflammatory disorders of the lower respiratory tract. The Journal of clinical investigation. 1984 Academic Article GET IT
- Elastin mRNA levels during foetal development of sheep nuchal ligament and lung. Hybridization to complementary and cloned DNA. The Biochemical journal. 1984 Academic Article GET IT
-
Sheep elastin genes. Isolation and preliminary characterization of a 9.9-kilobase genomic clone.
The Biochemical journal.
1984
Academic Article
GET IT
Times cited: 11 -
Lysosomal function in the degradation of defective collagen in cultured lung fibroblasts.
Biochemistry.
1984
Academic Article
GET IT
Times cited: 26 - Hereditary emphysema in the tight-skin mouse. Evaluation of pathogenesis. The American review of respiratory disease. 1984 Academic Article GET IT
-
Importance of the lower respiratory tract in oxygen transfer. Exercise testing in patients with interstitial and destructive lung disease.
The American review of respiratory disease.
1984
Academic Article
GET IT
Times cited: 51 -
Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract.
The New England journal of medicine.
1984
Information Resource
GET IT
Times cited: 250 -
Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract (first of two parts).
The New England journal of medicine.
1984
Information Resource
GET IT
Times cited: 421 -
Current concepts of the pathogenesis of fibrosis: lessons from pulmonary fibrosis.
Progress in clinical and biological research.
1984
Information Resource
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Times cited: 18 -
Paraquat-induced pulmonary fibrosis. Role of the alveolitis in modulating the development of fibrosis.
The American review of respiratory disease.
1984
Academic Article
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Times cited: 76 -
Response of the lower respiratory tract to injury. Mechanisms of repair of the parenchymal cells of the alveolar wall.
Chest.
1983
Information Resource
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Times cited: 26 -
Role of fibronectin as a growth factor for fibroblasts.
The Journal of cell biology.
1983
Academic Article
GET IT
Times cited: 220 -
Cigarette smoking and lung destruction. Accumulation of neutrophils in the lungs of cigarette smokers.
The American review of respiratory disease.
1983
Academic Article
GET IT
Times cited: 382 -
Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders.
The Journal of clinical investigation.
1983
Academic Article
GET IT
Times cited: 152 -
Ascorbate deficiency results in decreased collagen production: under-hydroxylation of proline leads to increased intracellular degradation.
Archives of biochemistry and biophysics.
1983
Academic Article
GET IT
Times cited: 51 -
Pulmonary oxygen toxicity. Early reversible changes in human alveolar structures induced by hyperoxia.
The New England journal of medicine.
1983
Academic Article
GET IT
Times cited: 206 -
Fibronectin mediates cell attachment to C1q: a mechanism for the localization of fibrosis in inflammatory disease.
Clinical and experimental immunology.
1983
Academic Article
GET IT
Times cited: 17 -
The alveolitis of pulmonary sarcoidosis. Evaluation of natural history and alveolitis-dependent changes in lung function.
The American review of respiratory disease.
1983
Academic Article
GET IT
Times cited: 133 -
The development of alveolar septa in fetal sheep lung. An ultrastructural and immunohistochemical study.
The American journal of anatomy.
1983
Academic Article
GET IT
Times cited: 47 -
Fibroblasts: important producers and targets of inflammatory prostaglandins in the lungs.
Chest.
1983
Academic Article
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Times cited: 2 -
Pulmonary oxygen toxicity. Bronchoalveolar lavage demonstration of early parameters of alveolitis.
Chest.
1983
Academic Article
GET IT
Times cited: 9 -
Role of fibronectin in fibrotic lung disease. A growth factor for human lung fibroblasts.
Chest.
1983
Academic Article
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Times cited: 7 -
Role of proteolytic and oxidative products of the neutrophil in determining the specificity of the pulmonary lesion in fibrotic and destructive lung disease.
Chest.
1983
Academic Article
GET IT
Times cited: 5 -
Spontaneous release of interleukin-2 by lung T lymphocytes in active pulmonary sarcoidosis.
The New England journal of medicine.
1983
Academic Article
GET IT
Times cited: 251 -
Hypersensitivity pneumonitis in man. Light- and electron-microscopic studies of 18 lung biopsies.
The American journal of pathology.
1983
Academic Article
GET IT
Times cited: 130 -
Experience with replacement therapy in the destructive lung disease associated with severe alpha-1-antitrypsin deficiency.
The American review of respiratory disease.
1983
Academic Article
GET IT
Times cited: 36 - Effect of intermittent high dose parenteral corticosteroids on the alveolitis of idiopathic pulmonary fibrosis. The American review of respiratory disease. 1983 Academic Article GET IT
-
Regional localization of the human alpha 2(I) collagen gene on chromosome 7 by molecular hybridization.
Cytogenetics and cell genetics.
1983
Academic Article
GET IT
Times cited: 37 -
Copy number of a human type I alpha 2 collagen gene.
The Journal of biological chemistry.
1982
Academic Article
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Times cited: 27 -
Role of alveolar macrophages in asbestosis: modulation of neutrophil migration to the lung after acute asbestos exposure.
Thorax.
1982
Academic Article
GET IT
Times cited: 38 -
Characterization of a signal peptide sequence in the cell-free translation product of sheep elastin mRNA.
Archives of biochemistry and biophysics.
1982
Academic Article
GET IT
Times cited: 14 -
Human alveolar macrophage growth factor for fibroblasts. Regulation and partial characterization.
The Journal of clinical investigation.
1982
Academic Article
GET IT
Times cited: 175 -
The collagen alpha-2 chain gene.
The Journal of investigative dermatology.
1982
Academic Article
GET IT
Times cited: 2 -
The molecular aspects of elastin gene expression.
The Journal of investigative dermatology.
1982
Academic Article
GET IT
Times cited: 7 - Modulation of collagen production by fibroblasts. Effects of chronic exposure to agonists that increase intracellular cyclic AMP. The Biochemical journal. 1982 Academic Article GET IT
- Interstitial lung disease: aggressive clinical management versus diagnostic and therapeutic nihilism. The Western journal of medicine. 1982 Academic Article GET IT
-
Regulation of elastin synthesis in developing sheep nuchal ligament by elastin mRNA levels.
The Journal of biological chemistry.
1982
Academic Article
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Times cited: 45 -
Alveolitis: the key to the interstitial lung disorders.
Thorax.
1982
Information Resource
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Times cited: 128 -
Fibronectin in human bronchopulmonary lavage fluid. Elevation in patients with interstitial lung disease.
The Journal of clinical investigation.
1982
Academic Article
GET IT
Times cited: 107 - Lung inflammation in sarcoidosis: comparison of serum angiotensin-converting enzyme levels with bronchoalveolar lavage and gallium-67 scanning assessment of the T lymphocyte alveolitis. Thorax. 1982 Academic Article GET IT
-
Structure of alveolar epithelial cells in patients with fibrotic lung disorders.
Laboratory investigation; a journal of technical methods and pathology.
1982
Academic Article
GET IT
Times cited: 146 -
Modulation of tropoelastin production and elastin messenger ribonucleic acid activity in developing sheep lung.
Biochemistry.
1981
Academic Article
GET IT
Times cited: 44 -
Oxidant injury of lung parenchymal cells.
The Journal of clinical investigation.
1981
Academic Article
GET IT
Times cited: 122 -
Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases.
Proceedings of the National Academy of Sciences of the United States of America.
1981
Academic Article
GET IT
Times cited: 244 -
Replacement therapy of alpha 1-antitrypsin deficiency. Reversal of protease-antiprotease imbalance within the alveolar structures of PiZ subjects.
The Journal of clinical investigation.
1981
Academic Article
GET IT
Times cited: 224 - Antielastases of the human alveolar structures. Implications for the protease-antiprotease theory of emphysema. The Journal of clinical investigation. 1981 Academic Article GET IT
-
Procollagen messenger RNA levels and activity and collagen synthesis during the fetal development of sheep lung, tendon, and skin.
The Journal of biological chemistry.
1981
Academic Article
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Times cited: 39 -
Environmental lung disease and the interstitium.
Clinics in chest medicine.
1981
Information Resource
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Times cited: 18 -
Safety of fiberoptic bronchoalveolar lavage in evaluation of interstitial lung disease.
Chest.
1981
Academic Article
GET IT
Times cited: 77 -
Pulmonary sarcoidosis: a disorder mediated by excess helper T-lymphocyte activity at sites of disease activity.
The New England journal of medicine.
1981
Academic Article
GET IT
Times cited: 570 -
Asbestos stimulates alveolar macrophages to release a factor causing human lung fibroblasts to replicate.
Chest.
1981
Academic Article
GET IT
Times cited: 6 -
Inflammation and asbestosis: characterization and maintenance of alveolitis following acute asbestos exposure.
Chest.
1981
Academic Article
GET IT
Times cited: 7 -
Mechanisms of neutrophil accumulation in the lungs of patients with idiopathic pulmonary fibrosis.
The Journal of clinical investigation.
1981
Academic Article
GET IT
Times cited: 150 - Pulmonary asbestosis and idiopathic pulmonary fibrosis: pathogenetic parallels. Chest. 1981 Academic Article GET IT
-
Pulmonary connective tissue and environmental lung disease.
Chest.
1981
Academic Article
GET IT
Times cited: 4 -
Hereditary emphysema in the tight-skin (Tsk/+) mouse.
The American review of respiratory disease.
1981
Academic Article
GET IT
Times cited: 56 -
Elastin fragments attract macrophage precursors to diseased sites in pulmonary emphysema.
Science (New York, N.Y.).
1981
Academic Article
GET IT
Times cited: 161 -
Regulation of collagen production by the beta-adrenergic system.
The Journal of clinical investigation.
1981
Academic Article
GET IT
Times cited: 79 -
Characterization of the inflammatory and immune effector cells in the lung parenchyma of patients with interstitial lung disease.
The American review of respiratory disease.
1981
Academic Article
GET IT
Times cited: 165 -
Gallium-67 scanning to stage the alveolitis of sarcoidosis: correlation with clinical studies, pulmonary function studies, and bronchoalveolar lavage.
The American review of respiratory disease.
1981
Academic Article
GET IT
Times cited: 111 -
Procollagen production and procollagen messenger RNA levels and activity in human lung fibroblasts during periods of rapid and stationary growth.
The Journal of biological chemistry.
1981
Academic Article
GET IT
Times cited: 59 -
Interstitial lung disease: current concepts of pathogenesis, staging and therapy.
The American journal of medicine.
1981
Information Resource
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Times cited: 335 -
Pulmonary Langerhans' cells in patients with fibrotic lung disorders.
Laboratory investigation; a journal of technical methods and pathology.
1981
Academic Article
GET IT
Times cited: 53 -
Developmental regulation of elastin synthesis.
Connective tissue research.
1981
Academic Article
GET IT
Times cited: 7 -
Mechanisms of hypergammaglobulinemia in pulmonary sarcoidosis. Site of increased antibody production and role of T lymphocytes.
The Journal of clinical investigation.
1981
Academic Article
GET IT
Times cited: 167 -
Clinical significance of pulmonary function tests. Pulmonary function testing in interstitial pulmonary disease. What does it tell us?.
Chest.
1980
Academic Article
GET IT
Times cited: 90 - Functional correlates of lung involvement in Wegener's granulomatosis. Use of pulmonary function tests in staging and follow-up. The American journal of medicine. 1980 Academic Article GET IT
-
Human alveolar macrophage-derived chemotactic factor for neutrophils. Stimuli and partial characterization.
The Journal of clinical investigation.
1980
Academic Article
GET IT
Times cited: 145 -
Human neutrophil elastase functions as a type III collagen "collagenase".
Biochemical and biophysical research communications.
1980
Academic Article
GET IT
Times cited: 88 -
Secondary structures for splice junctions in eukaryotic and viral messenger RNA precursors.
Nucleic acids research.
1980
Academic Article
GET IT
Times cited: 10 -
Collagen concentration and rates of synthesis in idiopathic pulmonary fibrosis.
The American review of respiratory disease.
1980
Academic Article
GET IT
Times cited: 65 -
Regulation of the production of secretory proteins: intracellular degradation of newly synthesized "defective" collagen.
Proceedings of the National Academy of Sciences of the United States of America.
1980
Academic Article
GET IT
Times cited: 151 - Danazol-induced augmentation of serum alpha 1-antitrypsin levels in individuals with marked deficiency of this antiprotease. The Journal of clinical investigation. 1980 Academic Article GET IT
-
Subplasmalemmal linear densities in cells of the mononuclear phagocyte system in lung.
The American journal of pathology.
1980
Academic Article
GET IT
Times cited: 29 -
Control of collagen production by human diploid lung fibroblasts.
The Journal of biological chemistry.
1980
Academic Article
GET IT
Times cited: 107 -
Chronic airflow obstruction in Fabry's disease.
The American journal of medicine.
1980
Academic Article
GET IT
Times cited: 51 -
Structural organization of a 17 KB segment of the alpha 2 collagen gene: evaluation by R loop mapping.
Nucleic acids research.
1980
Academic Article
GET IT
Times cited: 16 -
Effect of cyclic AMP on the intracellular degradation of newly synthesized collagen.
The Journal of biological chemistry.
1980
Academic Article
GET IT
Times cited: 139 -
Isolation and characterization of a 15-kilobase genomic sequence coding for part of the Pro alpha 2 chain of sheep type I collagen.
The Journal of biological chemistry.
1980
Academic Article
GET IT
Times cited: 16 -
Regulation of the release of alveolar macrophage-derived neutrophil chemotactic factor.
The American review of respiratory disease.
1980
Academic Article
GET IT
Times cited: 56 - Maintenance of granuloma formation in pulmonary sarcoidosis by T lymphocytes within the lung. The New England journal of medicine. 1980 Academic Article GET IT
-
Radionuclide cinepneumography: flow-volume imaging of the respiratory cycle.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1980
Academic Article
GET IT
Times cited: 12 -
Danazol-induced elevation of serum alpha 1-antitrypsin in individuals with severe deficiency of this antiprotease.
Chest.
1980
Academic Article
GET IT
Times cited: 1 -
Mechanism by which cigarette smoke attracts polymorphonuclear leukocytes to lung.
Chest.
1980
Academic Article
GET IT
Times cited: 28 -
Evaluation of the protease-antiprotease theory of human destructive lung disease.
Bulletin europeen de physiopathologie respiratoire.
1980
Academic Article
GET IT
Times cited: 65 -
Opportunities for the specific therapy of destructive lung disease.
Bulletin europeen de physiopathologie respiratoire.
1980
Academic Article
GET IT
Times cited: 2 -
The tight-skin mouse: an animal model of inherited emphysema.
Bulletin europeen de physiopathologie respiratoire.
1980
Academic Article
GET IT
Times cited: 4 -
Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans.
Science (New York, N.Y.).
1979
Academic Article
GET IT
Times cited: 252 -
Flexible fiberoptic bronchoscopy of the rhesus monkey (Macaca mulatta).
Laboratory animal science.
1979
Academic Article
GET IT
Times cited: 5 -
Acute hypersensitivity pneumonitis: serial changes in lung lymphocyte subopulations after exposure to antigen.
The American review of respiratory disease.
1979
Academic Article
GET IT
Times cited: 33 - Collagenase in the lower respiratory tract of patients with idiopathic pulmonary fibrosis. The New England journal of medicine. 1979 Academic Article GET IT
-
Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse.
The American review of respiratory disease.
1979
Academic Article
GET IT
Times cited: 346 -
Inflammatory and immune processes in the human lung in health and disease: evaluation by bronchoalveolar lavage.
The American journal of pathology.
1979
Academic Article
GET IT
Times cited: 666 -
Anchoring fibrils in the normal canine respiratory system.
The American review of respiratory disease.
1979
Academic Article
GET IT
Times cited: 21 -
Localization of the immune response in sarcoidosis.
The American review of respiratory disease.
1979
Academic Article
GET IT
Times cited: 109 -
Ultrastructure of pulmonary mast cells in patients with fibrotic lung disorders.
Laboratory investigation; a journal of technical methods and pathology.
1979
Academic Article
GET IT
Times cited: 202 -
Synthesis and degradation of collagen by skin fibroblasts from controls and from patients with osteogenesis imperfecta.
FEBS letters.
1979
Academic Article
GET IT
Times cited: 23 -
Procollagen alpha2 mRNA is significantly different from procollagen alpha1(I) mRNA in size or secondary structure.
Biochemical and biophysical research communications.
1979
Academic Article
GET IT
Times cited: 11 -
Morphologic-physiologic correlates of the severity of fibrosis and degree of cellularity in idiopathic pulmonary fibrosis.
The Journal of clinical investigation.
1979
Academic Article
GET IT
Times cited: 179 -
Destruction of a major extracellular adhesive glycoprotein (fibronectin) of human fibroblasts by neutral proteases from polymorphonuclear leukocyte granules.
Laboratory investigation; a journal of technical methods and pathology.
1979
Academic Article
GET IT
Times cited: 79 -
Comparison of the alveolitis of sarcoidosis and idiopathic pulmonary fibrosis.
Chest.
1979
Academic Article
GET IT
Times cited: 8 -
Nuclear inclusions in alveolar epithelium of patients with fibrotic lung disorders.
The American journal of pathology.
1979
Academic Article
GET IT
Times cited: 27 -
Pathogenetic studies in idiopathic pulmonary fibrosis. Control of neutrophil migration by immune complexes.
Chest.
1979
Academic Article
GET IT
Times cited: 10 - Bronchoalveolar lavage in interstitial lung disease. Annals of internal medicine. 1978 Academic Article GET IT
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Anchoring fibrils. A new connective tissue structure in fibrotic lung disease.
The American journal of pathology.
1978
Academic Article
GET IT
Times cited: 28 -
Gallium-67 citrate scanning in the staging of idiopathic pulmonary fibrosis: Correlation and physiologic and morphologic features and bronchoalveolar lavage.
The American review of respiratory disease.
1978
Academic Article
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Times cited: 99 -
Distribution of HLA antigens in idiopathic pulmonary fibrosis.
The American review of respiratory disease.
1978
Academic Article
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Times cited: 23 -
Degradation of newly synthesized collagen.
The Journal of biological chemistry.
1978
Academic Article
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Times cited: 177 -
Association in normal human fibroblasts of elevated levels of adenosine 3':5'-monophosphate with a selective decrease in collagen production.
The Journal of biological chemistry.
1978
Academic Article
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Times cited: 77 -
Cells, collagen and idiopathic pulmonary fibrosis.
Lung.
1978
Academic Article
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Times cited: 47 -
Metabolic fate of the major cell surface protein of normal human fibroblasts.
Biochemical and biophysical research communications.
1977
Academic Article
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Times cited: 46 -
Small airways in idiopathic pulmonary fibrosis. Comparison of morphologic and physiologic observations.
The Journal of clinical investigation.
1977
Academic Article
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Times cited: 111 -
Granulocyte collagenase: selective digestion of type I relative to type III collagen.
Proceedings of the National Academy of Sciences of the United States of America.
1977
Academic Article
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Times cited: 159 -
Thermodynamic resolution of the iron-sulfur centers of the succinic dehydrogenase of Rhodopseudomonas sphaeroides.
Archives of biochemistry and biophysics.
1977
Academic Article
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Times cited: 30 -
Alveolar multiplication in the contralateral lung after unilateral pneumonectomy in the rabbit.
The American review of respiratory disease.
1977
Academic Article
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Times cited: 44 - Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis. The Journal of clinical investigation. 1977 Academic Article GET IT
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Activation of alveolar macrophage collagenase by a neutral protease secreted by the same cell.
Nature.
1976
Academic Article
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Times cited: 44 - Idiopathic pulmonary fibrosis. Clinical, histologic, radiographic, physiologic, scintigraphic, cytologic, and biochemical aspects. Annals of internal medicine. 1976 Information Resource GET IT
- Pathogenic mechanisms in pulmonary fibrosis: collagen-induced migration inhibition factor production and cytotoxicity mediated by lymphocytes. The Journal of clinical investigation. 1976 Academic Article GET IT
-
Collagenase from rabbit pulmonary alveolar macrophages.
Biochemical and biophysical research communications.
1976
Academic Article
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Times cited: 42 -
Biochemical approaches to the investigation of fibrotic lung disease.
Chest.
1976
Academic Article
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Times cited: 7 -
Diffuse fibrotic lung disease: a correlative study.
Chest.
1976
Academic Article
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Times cited: 11 -
Lung collagen heterogeneity. Synthesis of type I and type III collagen by rabbit and human lung cells in culture.
The Journal of clinical investigation.
1976
Academic Article
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Times cited: 44 -
Content and synthesis of glycosaminoglycans in the developing lung.
The Journal of clinical investigation.
1975
Academic Article
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Times cited: 47 -
The connective tissue of lung.
The American review of respiratory disease.
1975
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Times cited: 154 -
Characterization of cell-free synthesis of collagen by lung polysomes in a heterologous system.
The Journal of biological chemistry.
1975
Academic Article
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Times cited: 15 -
Collagen in the human lung. Quantitation of rates of synthesis and partial characterization of composition.
The Journal of clinical investigation.
1975
Academic Article
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Times cited: 59 -
Lung growth after unilateral pneumonectomy: quantitation of collagen synthesis and content.
The American review of respiratory disease.
1975
Academic Article
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Times cited: 54 -
Collagen in the lung: development of a technology applicable to human lung disease.
Chest.
1975
Academic Article
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Times cited: 2 -
Lung collagen: definition, diversity and development.
Federation proceedings.
1974
Information Resource
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Times cited: 27 -
Lung collagen heterogeneity.
Proceedings of the National Academy of Sciences of the United States of America.
1974
Academic Article
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Times cited: 37 -
Lung collagen composition and synthesis. Characterization and changes with age.
The Journal of biological chemistry.
1974
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Times cited: 113 -
Initiation of globin synthesis: assays.
Methods in enzymology.
1974
Academic Article
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Times cited: 61 -
Paper electrophoresis and chromatography of oligopeptides with N-terminal methionine.
Analytical biochemistry.
1973
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Times cited: 6 -
Initiation of globin synthesis in beta-thalassemia.
The New England journal of medicine.
1973
Academic Article
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Times cited: 9 -
Isolation of protein synthesis initiation factors from rabbit liver.
The Journal of biological chemistry.
1973
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Times cited: 41 -
Initiation of globin synthesis. Preparation and use of reticulocyte ribosomes retaining initiation region messenger ribonucleic acid fragments.
The Journal of biological chemistry.
1972
Academic Article
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Times cited: 27 - Initiation of globin synthesis. FEBS letters. 1972 Academic Article GET IT
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Initiation of hemoglobin synthesis: comparison of model reactions that use artificial templates with those using natural messenger RNA.
Proceedings of the National Academy of Sciences of the United States of America.
1972
Academic Article
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Times cited: 24 -
Requirement for GTP in the initiation process on reticulocyte ribosomes and ribosomal subunits.
Proceedings of the National Academy of Sciences of the United States of America.
1971
Academic Article
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Times cited: 34 -
Initial dipeptide formation in hemoglobin biosynthesis.
Proceedings of the National Academy of Sciences of the United States of America.
1971
Academic Article
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Times cited: 33 -
Effects of nephrectomy and ureteral occlusion on extracellular fluid measurements during shock.
Surgery, gynecology & obstetrics.
1970
Academic Article
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Times cited: 3 -
Cushing's syndrome caused by a metyrapone responsive adrenocortical adenoma.
The Journal of clinical endocrinology and metabolism.
1970
Academic Article
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Times cited: 8 -
Kinetics of monovalent and divalent anion distribution in hemorrhagic hypotension and hypoxemia.
Annals of surgery.
1969
Academic Article
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Times cited: 2 -
Influence of hemorrhagic hypotension on measurements of the extracellular fluid volume.
Surgery, gynecology & obstetrics.
1969
Academic Article
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Times cited: 17