ProCope--protein complex prediction and evaluation. Academic Article uri icon

Overview

abstract

  • SUMMARY: Recent advances in high-throughput technology have increased the quantity of available data on protein complexes and stimulated the development of many new prediction methods. In this article, we present ProCope, a Java software suite for the prediction and evaluation of protein complexes from affinity purification experiments which integrates the major methods for calculating interaction scores and predicting protein complexes published over the last years. Methods can be accessed via a graphical user interface, command line tools and a Java API. Using ProCope, existing algorithms can be applied quickly and reproducibly on new experimental results, individual steps of the different algorithms can be combined in new and innovative ways and new methods can be implemented and integrated in the existing prediction framework. AVAILABILITY: Source code and executables are available at http://www.bio.ifi.lmu.de/Complexes/ProCope/.

publication date

  • July 17, 2008

Research

keywords

  • Multiprotein Complexes
  • Software

Identity

Scopus Document Identifier

  • 51749116241

Digital Object Identifier (DOI)

  • 10.1093/bioinformatics/btn376

PubMed ID

  • 18635566

Additional Document Info

volume

  • 24

issue

  • 18