Heterogeneity of embryonic and adult stem cells. Review uri icon

Overview

abstract

  • New studies suggest that stem cells of embryonic, neural, and hematopoietic origin are heterogeneous, with cells moving between two or more metastable states. These cell states show a bias in their differentiation potential and correlate with specific patterns of transcription factor expression and chromatin modifications.

publication date

  • November 6, 2008

Research

keywords

  • Adult Stem Cells
  • Cell Lineage
  • Embryonic Stem Cells
  • Epigenesis, Genetic
  • Gene Expression Regulation, Developmental
  • Hematopoietic Stem Cells

Identity

Scopus Document Identifier

  • 54949110207

Digital Object Identifier (DOI)

  • 10.1016/j.stem.2008.10.007

PubMed ID

  • 18983963

Additional Document Info

volume

  • 3

issue

  • 5