publication venue for
- An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study- Identified Diabetes Genes and Drug Discovery. 2024
- Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection. 2024
- Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies. 2024
- Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration. 2024
- Sham surgery for the trialing of cell-based therapies to the CNS may not be necessary.. 31. 2024
- SARS-CoV-2 infection causes dopaminergic neuron senescence. 2024
- A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS. 2023
- SON is an essential m6A target for hematopoietic stem cell fate.. 30. 2023
- Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity.. 30. 2023
- Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths. 2023
- Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy.. 30. 2023
- hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease.. 30. 2023
- A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.. 29. 2022
- Lymphatics act as a signaling hub to regulate intestinal stem cell activity.. 29. 2022
- An injury-responsive Rac-to-Rho GTPase switch drives activation of muscle stem cells through rapid cytoskeletal remodeling.. 29. 2022
- Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction. 2022
- SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. 2021
- Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression.. 28. 2021
- Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma.. 28. 2021
- Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use.. 28. 2021
- Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01.. 28. 2021
- A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes.. 27. 2020
- A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.. 27. 2020
- Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer.. 26. 2020
- Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation.. 25. 2019
- Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs.. 25. 2019
- Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.. 22. 2017
- Injury Activates Transient Olfactory Stem Cell States with Diverse Lineage Capacities.. 21. 2017
- Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.. 21. 2017
- A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages.. 21. 2017
- Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1.. 21. 2017
- Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes.. 21. 2017
- High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.. 21. 2017
- Deconstructing Olfactory Stem Cell Trajectories at Single-Cell Resolution.. 20. 2017
- Single-Cell 5-Formylcytosine Landscapes of Mammalian Early Embryos and ESCs at Single-Base Resolution.. 20. 2017
- Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.. 20. 2017
- Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development.. 20. 2017
- An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery.. 19. 2016
- Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells.. 19. 2016
- Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming.. 18. 2016
- A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.. 18. 2016
- Functional Connectivity under Optogenetic Control Allows Modeling of Human Neuromuscular Disease.. 18. 2015
- Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells.. 17. 2015
- Stem Cells and Aging: What's Next?. 16. 2015
- The long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells.. 16. 2015
- Human embryonic stem cell-derived oligodendrocyte progenitors remyelinate the brain and rescue behavioral deficits following radiation.. 16. 2015
- F-class cells: new routes and destinations for induced pluripotency.. 16. 2015
- Histone variant H2A.X deposition pattern serves as a functional epigenetic mark for distinguishing the developmental potentials of iPSCs.. 15. 2014
- Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells.. 15. 2014
- Human iPSC-based modeling of late-onset disease via progerin-induced aging.. 13. 2013
- Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics.. 13. 2013
- KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.. 12. 2013
- Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.. 12. 2013
- A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.. 12. 2013
- Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells.. 12. 2013
- Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo.. 12. 2013
- Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected].. 12. 2013
- MEF promotes stemness in the pathogenesis of gliomas.. 11. 2012
- Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system.. 11. 2012
- Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways.. 11. 2012
- Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.. 11. 2012
- The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development.. 11. 2012
- Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.. 9. 2011
- Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice.. 9. 2011
- miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells.. 8. 2011
- Signaling through BMPR-IA regulates quiescence and long-term activity of neural stem cells in the adult hippocampus.. 7. 2010
- Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.. 6. 2010
- Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.. 6. 2010
- Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease.. 5. 2009
- FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis.. 5. 2009
- SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma.. 4. 2009
- Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.. 4. 2009
- Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells.. 4. 2009
- PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells.. 4. 2009
- Hair follicle stem cells are specified and function in early skin morphogenesis.. 3. 2008
- Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse.. 2. 2008
- The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells.. 2. 2008
- Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse.. 2. 2008
- The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway.. 1. 2007
- Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution.. 1. 2007
- Shaping the Pluripotent Genome: Switches, Borders, and Loops.. 22. 2018
- Fishing for a WNT-PGE2 link: beta-catenin is caught in the stem cell net-work.. 4. 2009
- New readers and writers of RNA modifications unique to leukemia stem cells. 2023
- Expanding the precision oncology toolkit with micro-organospheres for early cancer diagnosis. 2022
- Human biliary epithelial cells for regenerative medicine. 2022
- Plasticity in Motion: Shape-Shifting Lgr5-Cells Initiate Colorectal Cancer Metastasis. 2020
- Evaluation of Stuart et al.: Distinct Molecular Trajectories Converge to Induce Naive Pluripotency. 2019
- Tolerance induction by allogeneic hematopoietic stem cells. 2011
- Does N-cadherin regulate interaction of hematopoietic stem cells with their niches? 2007
- Benefits of utilizing gene-modified iPSCs for clinical applications. 2010
- Tumor-initiating cells are rare in many human tumors. 2010
- New cell sources for T cell engineering and adoptive immunotherapy. 2015
- The potential of stem cells as an in vitro source of red blood cells for transfusion. 2012
- TET family proteins and their role in stem cell differentiation and transformation. 2011
- Human pluripotent-stem-cell-derived organoids for drug discovery and evaluation. 2023
- Constructing and Deconstructing Cancers using Human Pluripotent Stem Cells and Organoids. 2018
- Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies. 2018
- Heterogeneity of embryonic and adult stem cells. 2008