Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung. Review uri icon

Overview

abstract

  • Maintenance of epithelial barrier function in the skin, respiratory tract and intestine is critical to limit exposure to commensal and pathogenic microbes and to maintain tissue homeostasis. Innate lymphoid cells (ILCs) are a recently recognized innate immune cell population that plays critical roles in host defense, regulation of inflammation and promotion of wound healing and tissue repair at barrier surfaces. In this review we discuss recent advances in the understanding of how ILC populations in the respiratory tract impact allergic airway inflammation and lung epithelial repair.

publication date

  • April 20, 2012

Research

keywords

  • Asthma
  • Immunity, Innate
  • Lymphocytes

Identity

PubMed Central ID

  • PMC3383398

Scopus Document Identifier

  • 84862688241

Digital Object Identifier (DOI)

  • 10.1016/j.coi.2012.03.012

PubMed ID

  • 22521139

Additional Document Info

volume

  • 24

issue

  • 3