Successful treatment of a mycophenolate mofetil-refractory proliferative lupus nephritis with Belimumab in a 19-year-old woman. uri icon

Overview

abstract

  • We report the case of a 19-year-old woman with progressive proliferative lupus nephritis (LN) class III after induction and maintenance therapy with mycophenolate mofetil (MMF). Despite a satisfying clinical improvement proteinuria progressed under this medication. We treated the patient with additional belimumab after discussing other options. Following treatment with belimumab, proteinuria rapidly improved to almost normal levels and clinical remission lasted. Belimumab might hold promise for this indication.

publication date

  • September 6, 2013

Research

keywords

  • Antibodies, Monoclonal, Humanized
  • Immunosuppressive Agents
  • Lupus Nephritis

Identity

Scopus Document Identifier

  • 84887912448

Digital Object Identifier (DOI)

  • 10.1177/0961203313504145

PubMed ID

  • 24014569

Additional Document Info

volume

  • 22

issue

  • 14