Intrinsically germanium-69-labeled iron oxide nanoparticles: synthesis and in-vivo dual-modality PET/MR imaging. Academic Article uri icon

Overview

abstract

  • Intrinsically germanium-69-labeled super-paramagnetic iron oxide nanoparticles are synthesized via a newly developed, fast and highly specific chelator-free approach. The biodistribution pattern and the feasibility of (69) Ge-SPION@PEG for in vivo dual-modality positron emission tomography/magnetic resonance (PET/MR) imaging and lymph-node mapping are investigated, which represents the first example of the successful utilization of a (69) Ge-based agent for PET/MR imaging.

publication date

  • June 18, 2014

Research

keywords

  • Germanium
  • Magnetic Resonance Imaging
  • Magnetite Nanoparticles
  • Multimodal Imaging
  • Positron-Emission Tomography
  • Radioisotopes
  • Whole Body Imaging

Identity

PubMed Central ID

  • PMC4127144

Scopus Document Identifier

  • 84905825940

Digital Object Identifier (DOI)

  • 10.1002/adma.201401372

PubMed ID

  • 24944166

Additional Document Info

volume

  • 26

issue

  • 30