Chen, Feng

Publications

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selected publications

Ultrasmall Folate Receptor Alpha Targeted Enzymatically Cleavable Silica Nanoparticle Drug Conjugates Augment Penetration and Therapeutic Efficacy in Models of Cancer. ACS nano. 2022 Academic Article GET IT
Times cited: 1
Engineered Ultrasmall Nanoparticle Drug-Immune Conjugates with "Hit and Run" Tumor Delivery to Eradicate Gastric Cancer. Advanced therapeutics. 2022 Academic Article GET IT
Ultrasmall Nanoparticle Delivery of Doxorubicin Improves Therapeutic Index for High-Grade Glioma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2022 Academic Article GET IT
Times cited: 12
The Effect of Abnormal Regional Homogeneity and Spontaneous Low-Frequency Brain Activity on Lower Cognitive Ability: A Cross-Sectional Study on Postoperative Children With Tetralogy of Fallot. Frontiers in neuroscience. 2022 Academic Article GET IT
Times cited: 3
Causal structural covariance network revealing atrophy progression in Alzheimer's disease continuum. Human brain mapping. 2021 Academic Article GET IT
Times cited: 30
CT texture analysis for the presurgical prediction of superior mesenteric-portal vein invasion in pancreatic ductal adenocarcinoma: comparison with CT imaging features. Clinical radiology. 2021 Academic Article GET IT
Times cited: 7
Molecular Engineering of Ultrasmall Silica Nanoparticle-Drug Conjugates as Lung Cancer Therapeutics. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020 Academic Article GET IT
Times cited: 20
Targeted melanoma radiotherapy using ultrasmall ¹⁷⁷Lu-labeled α-melanocyte stimulating hormone-functionalized core-shell silica nanoparticles. Biomaterials. 2020 Academic Article GET IT
Times cited: 46
A Genomic Profile of Local Immunity in the Melanoma Microenvironment Following Treatment with α Particle-Emitting Ultrasmall Silica Nanoparticles. Cancer biotherapy & radiopharmaceuticals. 2020 Academic Article GET IT
Times cited: 17
Molecular phenotyping and image-guided surgical treatment of melanoma using spectrally distinct ultrasmall core-shell silica nanoparticles. Science advances. 2019 Academic Article GET IT
Times cited: 42
Ultrasmall Renally Clearable Silica Nanoparticles Target Prostate Cancer. ACS applied materials & interfaces. 2019 Academic Article GET IT
Times cited: 33
Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019 Academic Article GET IT
Times cited: 69
Correction: Camptothecin suppresses NRF2-ARE activity and sensitises hepatocellular carcinoma cells to anticancer drugs. 2019 GET IT
Times cited: 3
Ultrasmall targeted nanoparticles with engineered antibody fragments for imaging detection of HER2-overexpressing breast cancer. Nature communications. 2018 Academic Article GET IT
Times cited: 149
In Vivo Tumor-Targeted Dual-Modality PET/Optical Imaging with a Yolk/Shell-Structured Silica Nanosystem. Nano-micro letters. 2018 Academic Article GET IT
Times cited: 36
General synthesis of silica-based yolk/shell hybrid nanomaterials and in vivo tumor vasculature targeting. Nano research. 2018 Academic Article GET IT
Times cited: 28
Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy. Biomaterials. 2018 Academic Article GET IT
Times cited: 134
Melanocortin-1 Receptor-Targeting Ultrasmall Silica Nanoparticles for Dual-Modality Human Melanoma Imaging. ACS applied materials & interfaces. 2018 Academic Article GET IT
Times cited: 41
Activatable Hybrid Nanotheranostics for Tetramodal Imaging and Synergistic Photothermal/Photodynamic Therapy. Advanced materials (Deerfield Beach, Fla.). 2017 Academic Article GET IT
Times cited: 172
Cancer-Targeting Ultrasmall Silica Nanoparticles for Clinical Translation: Physicochemical Structure and Biological Property Correlations. Chemistry of materials : a publication of the American Chemical Society. 2017 Academic Article GET IT
Times cited: 61
Target-or-Clear Zirconium-89 Labeled Silica Nanoparticles for Enhanced Cancer-Directed Uptake in Melanoma: A Comparison of Radiolabeling Strategies. Chemistry of materials : a publication of the American Chemical Society. 2017 Academic Article GET IT
Times cited: 63
Intrinsic radiolabeling of Titanium-45 using mesoporous silica nanoparticles. Acta pharmacologica Sinica. 2017 Academic Article GET IT
Times cited: 46
Intrinsic and Stable Conjugation of Thiolated Mesoporous Silica Nanoparticles with Radioarsenic. ACS applied materials & interfaces. 2017 Academic Article GET IT
Times cited: 39
Chelator-Free Radiolabeling of Nanographene: Breaking the Stereotype of Chelation. Angewandte Chemie (International ed. in English). 2017 Academic Article GET IT
Times cited: 63
Intrinsically ⁸⁹Zr-labeled Gd₂O₂S:Eu nanophosphors with high in vivo stability for dual-modality imaging. American journal of translational research. 2016 Academic Article GET IT
Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth. Nature nanotechnology. 2016 Academic Article GET IT
Times cited: 516
Positron emission tomography and nanotechnology: A dynamic duo for cancer theranostics. Advanced drug delivery reviews. 2016 Review GET IT
Times cited: 162
Biocompatibility and in vivo operation of implantable mesoporous PVDF-based nanogenerators. Nano energy. 2016 Academic Article GET IT
Times cited: 162
Engineering Intrinsically Zirconium-89 Radiolabeled Self-Destructing Mesoporous Silica Nanostructures for In Vivo Biodistribution and Tumor Targeting Studies. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2016 Academic Article GET IT
Times cited: 68
Re-assessing the enhanced permeability and retention effect in peripheral arterial disease using radiolabeled long circulating nanoparticles. Biomaterials. 2016 Academic Article GET IT
Times cited: 65
Long circulating reduced graphene oxide-iron oxide nanoparticles for efficient tumor targeting and multimodality imaging. Nanoscale. 2016 Academic Article GET IT
Times cited: 65
Intrinsically Zirconium-89 Labeled Gd2 O2 S:Eu Nanoprobes for In Vivo Positron Emission Tomography and Gamma-Ray-Induced Radioluminescence Imaging. Small (Weinheim an der Bergstrasse, Germany). 2016 Academic Article GET IT
Times cited: 30
Dynamic Positron Emission Tomography Imaging of Renal Clearable Gold Nanoparticles. Small (Weinheim an der Bergstrasse, Germany). 2016 Academic Article GET IT
Times cited: 71
Scintillating Nanoparticles as Energy Mediators for Enhanced Photodynamic Therapy. ACS nano. 2016 Review GET IT
Times cited: 313
Engineering of radiolabeled iron oxide nanoparticles for dual-modality imaging. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. 2015 Review GET IT
Times cited: 49
High Yield Production and Radiochemical Isolation of Isotopically Pure Arsenic-72 and Novel Radioarsenic Labeling Strategies for the Development of Theranostic Radiopharmaceuticals. Bioconjugate chemistry. 2015 Academic Article GET IT
Times cited: 37
Chelator-Free Labeling of Layered Double Hydroxide Nanoparticles for in Vivo PET Imaging. Scientific reports. 2015 Academic Article GET IT
Times cited: 55
Biodegradable and Renal Clearable Inorganic Nanoparticles. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2015 Academic Article GET IT
Times cited: 234
A porphyrin-PEG polymer with rapid renal clearance. Biomaterials. 2015 Academic Article GET IT
Times cited: 62
In Vivo Integrity and Biological Fate of Chelator-Free Zirconium-89-Labeled Mesoporous Silica Nanoparticles. ACS nano. 2015 Academic Article GET IT
Times cited: 132
In Vivo Tumor Vasculature Targeting of CuS@MSN Based Theranostic Nanomedicine. ACS nano. 2015 Academic Article GET IT
Times cited: 166
Gray matter abnormalities associated with betel quid dependence: a voxel-based morphometry study. American journal of translational research. 2015 Academic Article GET IT
Hexamodal imaging with porphyrin-phospholipid-coated upconversion nanoparticles. Advanced materials (Deerfield Beach, Fla.). 2015 Academic Article GET IT
Times cited: 190
Editorial: Image-Guided Drug Delivery: State of the Art. Current drug targets. 2015 Editorial Article GET IT
Highlights from the latest articles in nano-oncology. Nanomedicine (London, England). 2015 Academic Article GET IT
Highlights from the latest articles in nanomedicine for deep tumor imaging and phototherapy. Nanomedicine (London, England). 2015 Comment GET IT
Hollow mesoporous silica nanoparticles for tumor vasculature targeting and PET image-guided drug delivery. Nanomedicine (London, England). 2015 Academic Article GET IT
Times cited: 81
Nanomedicine for targeted photothermal cancer therapy: where are we now?. Nanomedicine (London, England). 2015 Editorial Article GET IT
Times cited: 119
Theranostic nanoparticles. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2014 Review GET IT
Times cited: 261
VEGFR targeting leads to significantly enhanced tumor uptake of nanographene oxide in vivo. Biomaterials. 2014 Academic Article GET IT
Times cited: 68
VEGF₁₂₁-conjugated mesoporous silica nanoparticle: a tumor targeted drug delivery system. ACS applied materials & interfaces. 2014 Academic Article GET IT
Times cited: 130
Surface engineering of graphene-based nanomaterials for biomedical applications. Bioconjugate chemistry. 2014 Review GET IT
Times cited: 121
A smart upconversion-based mesoporous silica nanotheranostic system for synergetic chemo-/radio-/photodynamic therapy and simultaneous MR/UCL imaging. Biomaterials. 2014 Academic Article GET IT
Times cited: 245
New radiotracers for imaging of vascular targets in angiogenesis-related diseases. Advanced drug delivery reviews. 2014 Review GET IT
Times cited: 49
Intrinsically radiolabeled nanoparticles: an emerging paradigm. Small (Weinheim an der Bergstrasse, Germany). 2014 Academic Article GET IT
Times cited: 108
In vivo tumor vasculature targeted PET/NIRF imaging with TRC105(Fab)-conjugated, dual-labeled mesoporous silica nanoparticles. Molecular pharmaceutics. 2014 Academic Article GET IT
Times cited: 99
Intrinsically germanium-69-labeled iron oxide nanoparticles: synthesis and in-vivo dual-modality PET/MR imaging. Advanced materials (Deerfield Beach, Fla.). 2014 Academic Article GET IT
Times cited: 150
Engineering of hollow mesoporous silica nanoparticles for remarkably enhanced tumor active targeting efficacy. Scientific reports. 2014 Academic Article GET IT
Times cited: 210
Tumor vasculature targeting: a generally applicable approach for functionalized nanomaterials. Small (Weinheim an der Bergstrasse, Germany). 2014 Academic Article GET IT
Times cited: 78
Biomedical applications of functionalized hollow mesoporous silica nanoparticles: focusing on molecular imaging. Nanomedicine (London, England). 2013 Review GET IT
Times cited: 92
Chelator-free synthesis of a dual-modality PET/MRI agent. Angewandte Chemie (International ed. in English). 2013 Academic Article GET IT
Times cited: 113
In vivo tumor targeting and image-guided drug delivery with antibody-conjugated, radiolabeled mesoporous silica nanoparticles. ACS nano. 2013 Academic Article GET IT
Times cited: 328
Pharmacokinetic issues of imaging with nanoparticles: focusing on carbon nanotubes and quantum dots. Molecular imaging and biology. 2013 Review GET IT
Times cited: 24
Synthesis and biomedical applications of copper sulfide nanoparticles: from sensors to theranostics. Small (Weinheim an der Bergstrasse, Germany). 2013 Review GET IT
Times cited: 427
Molecular MRI of VEGFR-2 reveals intra-tumor and inter-tumor heterogeneity. American journal of nuclear medicine and molecular imaging. 2013 Academic Article GET IT

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Research

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Funding awarded

Targeting Inflammatory Pathways in Breast Cancer Brain Metastases for the Treatment of Edema and Radiation Necrosis Using Anti-VEGF Ultrasmall Particle Therapy awarded by United States Department of Defense Co-Investigator 2025 - 2027

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Background

education and training

Ph.D., Chinese Academy of Sciences, Shanghai (China) 2012
B.S., Nanjing University of Science and Technology (China) 2007

Contact

full name

Feng Chen

primary email

fec4008@med.cornell.edu

VIVO Weill Cornell Medical College

Feng Chen Instructor of Materials Physics in Radiology

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email