Engineering of radiolabeled iron oxide nanoparticles for dual-modality imaging. Review uri icon

Overview

abstract

  • Over the last decade, radiolabeled iron oxide nanoparticles have been developed as promising contrast agents for dual-modality positron emission tomography/magnetic resonance imaging (PET/MRI) or single-photon emission computed tomography/magnetic resonance imaging (SPECT/MRI). The combination of PET (or SPECT) with MRI can offer synergistic advantages for noninvasive, sensitive, high-resolution, and quantitative imaging, which is suitable for early detection of various diseases such as cancer. Here, we summarize the recent advances on radiolabeled iron oxide nanoparticles for dual-modality imaging, through the use of a variety of PET (and SPECT) isotopes by using both chelator-based and chelator-free radiolabeling techniques. WIREs Nanomed Nanobiotechnol 2016, 8:619-630. doi: 10.1002/wnan.1386.

publication date

  • December 22, 2015

Research

keywords

  • Image Processing, Computer-Assisted
  • Magnetite Nanoparticles

Identity

PubMed Central ID

  • PMC4911308

Scopus Document Identifier

  • 84975042193

Digital Object Identifier (DOI)

  • 10.1002/wnan.1386

PubMed ID

  • 26692551

Additional Document Info

volume

  • 8

issue

  • 4