Pediatric Gliomatosis Cerebri: A Review of 15 Years. Review uri icon

Overview

abstract

  • Gliomatosis cerebri is a rare glial tumor that carries a poor prognosis. Seen in both adults and children, gliomatosis cerebri appears to differ in these populations as with adult versus pediatric glioblastoma. We present 10 children who either presented to the Weill Cornell Medical College or enrolled in the institution's Gliomatosis Cerebri International Registry alongside a cohort of 89 pediatric patients reported in the literature between 2000 and 2014. Age ranged from 4 months to 21 years, with a male to female ratio of 1.71. Median overall survival for patients in the registry cohort was 17 months (n = 10) and for the historic cohort was 13 months (n = 52). Overall survival was analyzed for the combined cohort and was significantly longer when presenting at age ≥ 10 (20 vs 10 months), for boys (18 vs 11 months), and with low-grade pathology (26.5 vs 12 months) but did not vary significantly by treatment approach.

publication date

  • August 3, 2015

Research

keywords

  • Brain Neoplasms
  • Neoplasms, Neuroepithelial

Identity

Scopus Document Identifier

  • 84957866470

Digital Object Identifier (DOI)

  • 10.1177/0883073815596612

PubMed ID

  • 26239491

Additional Document Info

volume

  • 31

issue

  • 3