Telomerase Therapy to Reverse Cardiovascular Senescence. Review uri icon

Overview

abstract

  • Cellular senescence of endothelial cells plays an important role in the development of vascular lesions that ultimately lead to an atherosclerotic plaque. This review focuses on the age-related changes of endothelial and vascular smooth muscle cells that contribute to vascular disease and discusses potential new targets that could rejuvenate the vascular system and thereby prevent or delay atherosclerosis.

publication date

  • January 1, 2015

Research

keywords

  • Atherosclerosis
  • Cellular Senescence
  • Endothelial Cells
  • Endothelium, Vascular
  • Genetic Therapy
  • Regeneration
  • Telomerase

Identity

PubMed Central ID

  • PMC4666424

Scopus Document Identifier

  • 84979274339

Digital Object Identifier (DOI)

  • 10.14797/mdcj-11-3-172

PubMed ID

  • 26634025

Additional Document Info

volume

  • 11

issue

  • 3