Manifestations of systemic lupus erythematosus in female patients with polysomy X: Possible roles of chromosome X. uri icon

Overview

abstract

  • Clinical manifestations of systemic lupus erythematosus (SLE) in female patients with polysomy X have been less characterized as compared to those in male patients. Here, we describe a 28-year-old woman with trisomy X (47,XXX) who developed SLE. She had polyarthritis, hemolytic anemia, and was positive for anti-nuclear and anti-dsDNA antibodies. We discuss the common SLE manifestations with female polysomy X and the possible link between the development of SLE and the presence of extra X-chromosomes.

publication date

  • July 12, 2016

Research

keywords

  • Lupus Erythematosus, Systemic
  • Sex Chromosome Disorders of Sex Development

Identity

Scopus Document Identifier

  • 84978160582

Digital Object Identifier (DOI)

  • 10.1080/14397595.2016.1205800

PubMed ID

  • 27401488

Additional Document Info

volume

  • 29

issue

  • 1