A New Caged-Glutamine Derivative as a Tool To Control the Assembly of Glutamine-Containing Amyloidogenic Peptides. Academic Article uri icon

Overview

abstract

  • We present the design, synthesis, and characterization of a novel photocaged glutamine derivative (modified on the side chain of glutamine), and describe its use in enhancing peptide stability and solubility. Our results demonstrate that this approach can be used to develop molecular switches to control the folding and β-sheet formation of amyloidogenic peptides.

publication date

  • November 25, 2016

Research

keywords

  • Amyloid beta-Peptides
  • Glutamine

Identity

Scopus Document Identifier

  • 85005896302

Digital Object Identifier (DOI)

  • 10.1002/cbic.201600474

PubMed ID

  • 27788286

Additional Document Info

volume

  • 17

issue

  • 24