Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. uri icon

Overview

abstract

  • Active smoking in stable COPD subjects significantly increased eosinophil accumulation in the distal airspaces, but not in sputum or peripheral blood. Our findings support the need to investigate this cell-type as a potential driver of COPD symptomatology and progression.

publication date

  • September 12, 2017

Research

keywords

  • Eosinophilia
  • Pulmonary Alveoli
  • Pulmonary Disease, Chronic Obstructive
  • Smokers

Identity

PubMed Central ID

  • PMC5758424

Scopus Document Identifier

  • 85030867243

Digital Object Identifier (DOI)

  • 10.1016/j.jaci.2017.07.039

PubMed ID

  • 28916185

Additional Document Info

volume

  • 141

issue

  • 1