The Journal of allergy and clinical immunology

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Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration. 2024
Accelerated cell-mediated immune reactions in penicillin allergy. 1993
Acquired deficiency of the inhibitor of the first component of complement: report of five additional cases with commentary on the syndrome. 1985
Vernix caseosa reveals mechanistic clues linking maternal obesity to atopic dermatitis pathogenesis.. 153. 2023
Post-Transplant Late Complications Increase Over Time for Patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) Landmark Study. 2023
High plasma IL-6 levels may enhance the adverse effects of mouse allergen exposure in urban schools on asthma morbidity in children. 2023
Single-cell transcriptomics suggest distinct upstream drivers of IL-17A/F in hidradenitis versus psoriasis.. 152. 2023
The diagnosis of severe combined immunodeficiency (SCID): The Primary Immune Deficiency Treatment Consortium (PIDTC) 2022 Definitions.. 151. 2022
The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions.. 151. 2022
Aberrant T-cell exhaustion in severe combined immunodeficiency survivors with poor T-cell reconstitution after transplantation.. 151. 2022
Molecular and clinical effects of selective tyrosine kinase 2 inhibition with deucravacitinib in psoriasis. 2021
Pustular psoriasis: Molecular pathways and effects of spesolimab in generalized pustular psoriasis. 2021
Genetic errors of immunity distinguish pediatric nonmalignant lymphoproliferative disorders.. 149. 2021
Therapeutic options for CTLA-4 insufficiency.. 149. 2021
High inflammation in hidradenitis suppurativa extends to perilesional skin and can be subdivided by lipocalin-2 expression. 2021
Single-cell transcriptomics applied to emigrating cells from psoriasis elucidate pathogenic versus regulatory immune cell subsets. 2021
Epithelialized tunnels are a source of inflammation in hidradenitis suppurativa.. 147. 2021
The molecular features of normal and atopic dermatitis skin in infants, children, adolescents, and adults.. 148. 2021
Bone morphogenetic protein signaling regulates skin inflammation via modulating dendritic cell function.. 147. 2020
Mild atopic dermatitis lacks systemic inflammation and shows reduced nonlesional skin abnormalities.. 147. 2020
Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis.. 147. 2020
Obesity may enhance the adverse effects of NO₂ exposure in urban schools on asthma symptoms in children.. 146. 2020
Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis.. 145. 2020
Short-term transcriptional response to IL-17 receptor-A antagonism in the treatment of psoriasis.. 145. 2019
Evolution of pathologic T-cell subsets in patients with atopic dermatitis from infancy to adulthood.. 145. 2019
Phase 2B randomized study of nemolizumab in adults with moderate-to-severe atopic dermatitis and severe pruritus.. 145. 2019
Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis.. 144. 2019
Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis.. 144. 2019
IL-17A inhibition by secukinumab induces early clinical, histopathologic, and molecular resolution of psoriasis.. 144. 2019
The skin as an immune organ: Tolerance versus effector responses and applications to food allergy and hypersensitivity reactions.. 144. 2019
Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.. 144. 2019
Psoriatic skin molecular and histopathologic profiles after treatment with risankizumab versus ustekinumab.. 143. 2018
Blood endotyping distinguishes the profile of vitiligo from that of other inflammatory and autoimmune skin diseases.. 143. 2018
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis.. 143. 2018
Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab.. 143. 2018
Ichthyosis molecular fingerprinting shows profound T_H17 skewing and a unique barrier genomic signature.. 143. 2018
Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects.. 142. 2018
Early-onset pediatric atopic dermatitis is characterized by T_H2/T_H17/T_H22-centered inflammation and lipid alterations.. 141. 2018
Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase-induced inflammation.. 142. 2017
Staged development of long-lived T-cell receptor αβ T_H17 resident memory T-cell population to Candida albicans after skin infection.. 142. 2017
Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.. 141. 2017
Serum IgG and risk of exacerbations and hospitalizations in chronic obstructive pulmonary disease.. 140. 2017
Basophil-derived IL-4 promotes epicutaneous antigen sensitization concomitant with the development of food allergy.. 141. 2017
Regulated in development and DNA damage responses 1 (REDD1) links stress with IL-1β-mediated familial Mediterranean fever attack through autophagy-driven neutrophil extracellular traps.. 140. 2017
Alterations in B-cell subsets in pediatric patients with early atopic dermatitis.. 140. 2016
Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling.. 139. 2016
An IL-17-dominant immune profile is shared across the major orphan forms of ichthyosis.. 139. 2016
Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders.. 139. 2016
Anti-hIgE gene therapy of peanut-induced anaphylaxis in a humanized murine model of peanut allergy.. 138. 2016
Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus.. 139. 2016
Tofacitinib attenuates pathologic immune pathways in patients with psoriasis: A randomized phase 2 study.. 137. 2016
A mild topical steroid leads to progressive anti-inflammatory effects in the skin of patients with moderate-to-severe atopic dermatitis.. 138. 2016
The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases.. 137. 2015
Expansion of inflammatory innate lymphoid cells in patients with common variable immune deficiency.. 137. 2015
Diverse activation and differentiation of multiple B-cell subsets in patients with atopic dermatitis but not in patients with psoriasis.. 137. 2015
Petrolatum: Barrier repair and antimicrobial responses underlying this "inert" moisturizer.. 137. 2015
The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization.. 136. 2015
Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing.. 136. 2015
Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)(+) TH2/TH1 cell imbalance, whereas adults acquire CLA(+) TH22/TC22 cell subsets.. 136. 2015
RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications.. 135. 2015
Anti-IL-23A mAb BI 655066 for treatment of moderate-to-severe psoriasis: Safety, efficacy, pharmacokinetics, and biomarker results of a single-rising-dose, randomized, double-blind, placebo-controlled trial.. 136. 2015
Severe atopic dermatitis is characterized by selective expansion of circulating TH2/TC2 and TH22/TC22, but not TH17/TC17, cells within the skin-homing T-cell population.. 136. 2015
Patients with atopic dermatitis have attenuated and distinct contact hypersensitivity responses to common allergens in skin.. 135. 2015
Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.. 135. 2015
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis.. 134. 2014
Fatal anaphylaxis in the United States, 1999-2010: temporal patterns and demographic associations.. 134. 2014
Comparison of US emergency department acute asthma care quality: 1997-2001 and 2011-2012.. 135. 2014
Dry roasting enhances peanut-induced allergic sensitization across mucosal and cutaneous routes in mice.. 134. 2014
Risk factors for severe anaphylaxis in patients receiving anaphylaxis treatment in US emergency departments and hospitals.. 134. 2014
Clinical features and resolution of food protein-induced enterocolitis syndrome: 10-year experience.. 134. 2014
Cyclosporine in patients with atopic dermatitis modulates activated inflammatory pathways and reverses epidermal pathology.. 133. 2014
Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response.. 134. 2014
Guselkumab (an IL-23-specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis.. 133. 2014
Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis.. 133. 2014
Establishing diagnostic criteria for severe combined immunodeficiency disease (SCID), leaky SCID, and Omenn syndrome: the Primary Immune Deficiency Treatment Consortium experience.. 133. 2013
Primary Immune Deficiency Treatment Consortium (PIDTC) report.. 133. 2013
Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis.. 132. 2013
Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis.. 130. 2012
IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis.. 130. 2012
Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response.. 128. 2011
Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets.. 128. 2011
Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities.. 127. 2011
Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis.. 125. 2010
Regional and racial disparities in asthma hospitalizations in Mississippi.. 125. 2010
Voluntarily reported unintentional injections from epinephrine auto-injectors.. 125. 2010
Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis.. 124. 2009
Improving cellular therapy for primary immune deficiency diseases: recognition, diagnosis, and management.. 124. 2009
Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes.. 124. 2009
Mutation of tyrosine 145 of lymphocyte cytosolic protein 2 protects mice from anaphylaxis and arthritis.. 124. 2009
Anaphylaxis in the community: learning from the survivors.. 124. 2009
IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells.. 123. 2009
Sesame Allergy: Role of Specific IgE and Skin Prick Testing in Predicting Food Challenge Results.. 123. 2009
Improving asthma self-efficacy: developing and testing a pilot community-based asthma intervention for African American adults.. 123. 2009
Quality of care for acute asthma in 63 US emergency departments.. 123. 2008
Allogeneic hematopoietic cell transplantation for primary immune deficiency diseases: current status and critical needs.. 122. 2008
Onset of symptomatic effect of mometasone furoate nasal spray in the treatment of nasal polyposis.. 121. 2008
Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: clinical and immunologic outcomes in heterozygotes.. 120. 2007
Regional differences in EpiPen prescriptions in the United States: the potential role of vitamin D.. 120. 2007
Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis.. 119. 2007
Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility.. 118. 2006
Efficacy and safety of mometasone furoate nasal spray in nasal polyposis.. 116. 2005
Multicenter study of emergency department visits for insect sting allergies.. 116. 2005
Serum nutrient markers and skin prick testing using data from the Third National Health and Nutrition Examination Survey.. 114. 2004
Multicenter study of emergency department visits for food allergies.. 113. 2004
Histamine and tryptase levels in patients with acute allergic reactions: An emergency department-based study.. 106. 2000
Therapeutic efficacy of an anti-IL-5 monoclonal antibody delivered into the respiratory tract in a murine model of asthma.. 104. 1999
Chronic sinusitis: risk factors for extensive disease.. 100. 1997
Nebulized salbutamol with and without ipratropium bromide in the treatment of acute asthma.. 100. 1997
Decreased nasal goblet cells in patients reporting topical corticosteroid use.. 99. 1997
Polymorphism in transporter antigen peptides gene (TAP1) associated with atopy in Tunisians.. 99. 1997
A localized vaginal allergic response in women with recurrent vaginitis.. 81. 1988
Hereditary angioedema: a decade of management with stanozolol.. 80. 1987
IgE-mediated hypersensitivity in human heart tissue: histamine release and functional changes.. 77. 1986
Underestimation of specific immunoglobulin E by microtiter plate enzyme-linked immunosorbent assays.. 76. 1985
Kinin formation in hereditary angioedema plasma: evidence against kinin derivation from C2 and in support of "spontaneous" formation of bradykinin.. 72. 1983
Continuing medical education. This continuing medical education self-assessment program is sponsored by the American Academy of Allergy and Immunology and supported by a grant-in-aid from Fisons Corporation.. 71. 1983
Reduction of interference by specific IgG with a modified microtiter solid-phase radioimmunoassay to measure honeybee venom IgE.. 71. 1983
A quantitative enzyme-linked immunosorbent assay for honeybee venom-specific immunoglobulin G.. 70. 1982
Clinical and biochemical effects of stanozolol therapy for hereditary angioedema.. 68. 1981
Microtiter solid-phase radioimmunoassay for specific immunoglobulin E.. 67. 1981
Clinical and biochemical effects of impeded androgen (oxymetholone) therapy of hereditary angioedema.. 64. 1979
Response to corticosteroids in chronic bronchitis.. 62. 1978
Tranexamic acid: preoperative prophylactic therapy for patients with hereditary angioneurotic edema.. 60. 1977
Reply.. 138. 2016
Reply: To PMID 25748064.. 136. 2015
Trends in pediatric emergency department visits for food-induced anaphylaxis.. 126. 2010
Atopic dermatitis keratinocytes exhibit normal T(H)17 cytokine responses.. 125. 2010
17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry.. 124. 2009
Analysis of insect-sting study.. 96. 1995
Emapalumab as bridge to hematopoietic cell transplant for STAT1 gain-of-function mutations. 2023
Jakinibs for the treatment of immune dysregulation in patients with gain-of-function signal transducer and activator of transcription 1 (STAT1) or STAT3 mutations. 2018
Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. 2017
Atopic dermatitis endotypes and implications for targeted therapeutics. 2019
Psoriasis pathogenesis and the development of novel targeted immune therapies. 2017
Novel concepts of prevention and treatment of atopic dermatitis through barrier and immune manipulations with implications for the atopic march. 2017
Basophils and allergic inflammation. 2013
Proximal signaling events in Fc epsilon RI-mediated mast cell activation. 2007
Mechanisms of nutrient modulation of the immune response. 2005
21. Immunohematologic disorders. 2003
Epithelial-neuronal-immune cell interactions: implications for immunity, inflammation, and tissue homeostasis at mucosal sites. 2024
Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases. 2023
Chronic obstructive pulmonary disease subpopulations and phenotyping. 2018

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