Cross-cultural Validation of the 5-Factor Structure of Negative Symptoms in Schizophrenia. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: Negative symptoms are currently viewed as having a 2-dimensional structure, with factors reflecting diminished expression (EXP) and motivation and pleasure (MAP). However, several factor-analytic studies suggest that the consensus around a 2-dimensional model is premature. The current study investigated and cross-culturally validated the factorial structure of BNSS-rated negative symptoms across a range of cultures and languages. METHOD: Participants included individuals diagnosed with a psychotic disorder who had been rated on the Brief Negative Symptom Scale (BNSS) from 5 cross-cultural samples, with a total N = 1691. First, exploratory factor analysis was used to extract up to 6 factors from the data. Next, confirmatory factor analysis evaluated the fit of 5 models: (1) a 1-factor model, 2) a 2-factor model with factors of MAP and EXP, 3) a 3-factor model with inner world, external, and alogia factors; 4) a 5-factor model with separate factors for blunted affect, alogia, anhedonia, avolition, and asociality, and 5) a hierarchical model with 2 second-order factors reflecting EXP and MAP, as well as 5 first-order factors reflecting the 5 aforementioned domains. RESULTS: Models with 4 factors or less were mediocre fits to the data. The 5-factor, 6-factor, and the hierarchical second-order 5-factor models provided excellent fit with an edge to the 5-factor model. The 5-factor structure demonstrated invariance across study samples. CONCLUSIONS: Findings support the validity of the 5-factor structure of BNSS-rated negative symptoms across diverse cultures and languages. These findings have important implications for the diagnosis, assessment, and treatment of negative symptoms.

authors

  • Ahmed, Anthony O.
  • Kirkpatrick, Brian
  • Galderisi, Silvana
  • Mucci, Armida
  • Rossi, Alessandro
  • Bertolino, Alessandro
  • Rocca, Paola
  • Maj, Mario
  • Kaiser, Stefan
  • Bischof, Martin
  • Hartmann-Riemer, Matthias N
  • Kirschner, Matthias
  • Schneider, Karoline
  • Garcia-Portilla, Maria Paz
  • Mane, Anna
  • Bernardo, Miguel
  • Fernandez-Egea, Emilio
  • Jiefeng, Cui
  • Jing, Yao
  • Shuping, Tan
  • Gold, James M
  • Allen, Daniel N
  • Strauss, Gregory P

publication date

  • March 7, 2019

Research

keywords

  • Psychiatric Status Rating Scales
  • Psychotic Disorders
  • Schizophrenia

Identity

PubMed Central ID

  • PMC6403061

Scopus Document Identifier

  • 85062605317

Digital Object Identifier (DOI)

  • 10.1093/schbul/sby050

PubMed ID

  • 29912473

Additional Document Info

volume

  • 45

issue

  • 2