Production of high titre human interferon-gamma in primed leukocyte cultures. Academic Article uri icon

Overview

abstract

  • Con A-stimulated leukocytes previously treated with IFN-alpha (1500 IU/ml for 4 h) were very suitable for the production of IFN-gamma with a high titre even under large-scale conditions. The properties of the IFN produced under such conditions were identical to those of IFN-gamma. The IFN-gamma produced in primed cultures showed two peaks of antiviral activity corresponding to molecular weights of 51 000 and 23 000 daltons.

publication date

  • January 1, 1985

Research

keywords

  • Interferon-gamma
  • Leukocytes

Identity

Scopus Document Identifier

  • 0022240516

PubMed ID

  • 3012931

Additional Document Info

volume

  • 32

issue

  • 4