Apoptotic Caspases: A Double-Edged Sword in Radiation-Induced Immunogenicity. Article uri icon

Overview

abstract

  • In a recent study in Oncoimmunology, Rodriguez-Ruiz et al. demonstrate that the apoptotic executioner caspase 3 (CASP3) attenuates antitumor immune responses induced by radiation therapy (RT) by inhibiting the release of cytosolic DNA. CASP3 stands out as a promising target for the development of novel strategies to improve anticancer responses driven by RT.

publication date

  • October 14, 2019

Research

keywords

  • Apoptosis
  • Caspase 3
  • Neoplasms

Identity

Scopus Document Identifier

  • 85073500351

Digital Object Identifier (DOI)

  • 10.1016/j.tcb.2019.09.001

PubMed ID

  • 31623928

Additional Document Info

volume

  • 29

issue

  • 11