Hypoxia Conditioning as a Promising Therapeutic Target in Parkinson's Disease? Academic Article uri icon

Overview

abstract

  • Several lines of research point to a key role of low oxygen supply (hypoxia) in Parkinson's disease pathogenesis. Although severe hypoxia is detrimental for the brain, physiological adaptations to mild hypoxia are neuroprotective. Herein we discuss, how neuroprotective effects can be induced by hypoxia conditioning and how related approaches have the potential to be harnessed as therapeutic strategies in Parkinson's disease. © 2021 International Parkinson and Movement Disorder Society.

publication date

  • February 27, 2021

Research

keywords

  • Hypoxia
  • Parkinson Disease

Identity

Scopus Document Identifier

  • 85101801016

Digital Object Identifier (DOI)

  • 10.1002/mds.28544

PubMed ID

  • 33638916

Additional Document Info

volume

  • 36

issue

  • 4