Innovations in Neuro-Oncology. Academic Article uri icon

Overview

abstract

  • Although outcomes for many brain tumors, especially glioblastomas, remain poor, there have been significant advances in clinical and scientific understanding of neuro-oncologic disease. Tumor molecular profiling has become a critical component of clinical practice, allowing more accurate pathologic diagnosis and enhanced clarity of the pathogenesis of both primary and metastatic brain tumors. The development of cerebral organoids carries exciting potential to provide representative models of tumor growth and potential drug efficacy, while new radiology techniques continue to improve clinical decision making. New adaptive trial platforms have been developed to rapidly test therapies and biomarkers with good scientific rationale. Lastly, growth and development of neuro-oncology clinical care teams aim to further improve patients' outcomes and symptoms, especially at the end of life.

publication date

  • July 1, 2021

Research

keywords

  • Brain Neoplasms
  • Medical Oncology
  • Molecular Biology
  • Neurology

Identity

Scopus Document Identifier

  • 85109091987

Digital Object Identifier (DOI)

  • 10.1016/j.wneu.2021.02.093

PubMed ID

  • 34243672

Additional Document Info

volume

  • 151