Time-dependent diffusivity and kurtosis in phantoms and patients with head and neck cancer. Academic Article uri icon

Overview

abstract

  • PURPOSE: To assess the reliability of measuring diffusivity, diffusional kurtosis, and cellular-interstitial water exchange time with long diffusion times (100-800 ms) using stimulated-echo DWI. METHODS: D RESULTS: D CONCLUSIONS: Based on two well-established diffusion phantoms, we found that time-dependent diffusion MRI measurements can provide stable diffusion and kurtosis values over a wide range of diffusion times and across multiple MRI systems. Moreover, estimation of cellular-interstitial water exchange time can be achieved using the Kärger model for the metastatic lymph nodes in patients with head and neck cancer.

publication date

  • October 11, 2022

Research

keywords

  • Diffusion Magnetic Resonance Imaging
  • Head and Neck Neoplasms

Identity

Scopus Document Identifier

  • 85139486604

Digital Object Identifier (DOI)

  • 10.1002/mrm.29457

PubMed ID

  • 36219464